BacMap

Definition	Thermus thermophilus HB8 chromosome, complete genome.
Accession	NC_006461
Length	1,849,742

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The map label for this gene is dnaJ2

Identifier: 55981458

GI number: 55981458

Start: 1415715

End: 1416557

Strand: Reverse

Name: dnaJ2

Synonym: TTHA1489

Alternate gene names: 55981458

Gene position: 1416557-1415715 (Counterclockwise)

Preceding gene: 55981459

Following gene: 55981457

Centisome position: 76.58

GC content: 70.82

Gene sequence:

>843_bases
ATGGCGGCCAAGAAGGACTACTACGCCATCCTCGGGGTGCCGAGAAACGCCACCCAGGAGGAGATCAAGCGGGCCTACAA
GCGCCTGGCCCGCCAGTACCACCCGGACGTCAACAAAAGCCCCGAGGCGGAGGAGAAGTTCAAGGAGATCAACGAGGCCT
ACGCCGTCCTCTCCGACCCCGAGAAGCGCCGGATCTACGACACCTACGGCACCACCGAGGCCCCGCCCCCGCCGCCTCCC
GGGGGGTACGATTTCTCCGGGTTTGACGTGGAGGACTTCTCCGAGTTCTTCCAGGAGCTCTTCGGCCCCGGCCTCTTCGG
CGGCTTCGGGCGGCGGAGCCGCAAGGGGCGGGACCTCAGGGCCGAGCTGCCCCTCACCCTGGAGGAGGCCTTCCACGGCG
GGGAGAGGGTGGTGGAGGTGGCGGGTAGGCGCGTTTCCGTCCGCATCCCGCCCGGGGTGCGGGAGGGGAGCGTGATCCGG
GTCCCGGGGATGGGGGGGCAGGGGAACCCCCCTGGGGACCTCCTCCTCGTGGTGCGCCTCCTTCCCCACCCCGTCTTCCG
CCTCGAGGGCCAGGACCTCTACGCCACCCTGGACGTCCCCGCCCCCATCGCCGTGGTGGGGGGGAAGGTGCGGGCCATGA
CCCTGGAGGGCCCCGTGGAGGTCGCCGTCCCCCCAAGGACCCAGGCGGGGAGGAAGCTCCGGCTTAAGGGCAAGGGCTTC
CCCGGGCCCGCGGGCCGGGGCGACCTCTACCTGGAGGTGCGGATCACCATCCCCGAGCGCCTCACCCCCGAGGAAGAGGC
CCTCTGGAAGAAGCTCGCGGAGGCCTACTATGCTCGCGCGTAG

Upstream 100 bases:

>100_bases
GGTCTTCCAGCGGGGCTTCCGCATGGGCGAGGCCCTGGTGCGCCCGGCCCGGGTGGCCGTGGGCGAGGAGAAGCGGGAAG
AGGCGGACCTGGAGTAGCCT

Downstream 100 bases:

>100_bases
CGGTTGGCTTTCCCTCGAGGCCCTCTCCGAGTACGGCCTTTCCCTGGCGGCCGTGCGGGCCTACGTGGAGATCGGCTTCG
TGGAGCCTTTGGAGGTGGGC

Product: chaperone protein DnaJ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MAAKKDYYAILGVPRNATQEEIKRAYKRLARQYHPDVNKSPEAEEKFKEINEAYAVLSDPEKRRIYDTYGTTEAPPPPPP
GGYDFSGFDVEDFSEFFQELFGPGLFGGFGRRSRKGRDLRAELPLTLEEAFHGGERVVEVAGRRVSVRIPPGVREGSVIR
VPGMGGQGNPPGDLLLVVRLLPHPVFRLEGQDLYATLDVPAPIAVVGGKVRAMTLEGPVEVAVPPRTQAGRKLRLKGKGF
PGPAGRGDLYLEVRITIPERLTPEEEALWKKLAEAYYARA

Sequences:

>Translated_280_residues
MAAKKDYYAILGVPRNATQEEIKRAYKRLARQYHPDVNKSPEAEEKFKEINEAYAVLSDPEKRRIYDTYGTTEAPPPPPP
GGYDFSGFDVEDFSEFFQELFGPGLFGGFGRRSRKGRDLRAELPLTLEEAFHGGERVVEVAGRRVSVRIPPGVREGSVIR
VPGMGGQGNPPGDLLLVVRLLPHPVFRLEGQDLYATLDVPAPIAVVGGKVRAMTLEGPVEVAVPPRTQAGRKLRLKGKGF
PGPAGRGDLYLEVRITIPERLTPEEEALWKKLAEAYYARA
>Mature_279_residues
AAKKDYYAILGVPRNATQEEIKRAYKRLARQYHPDVNKSPEAEEKFKEINEAYAVLSDPEKRRIYDTYGTTEAPPPPPPG
GYDFSGFDVEDFSEFFQELFGPGLFGGFGRRSRKGRDLRAELPLTLEEAFHGGERVVEVAGRRVSVRIPPGVREGSVIRV
PGMGGQGNPPGDLLLVVRLLPHPVFRLEGQDLYATLDVPAPIAVVGGKVRAMTLEGPVEVAVPPRTQAGRKLRLKGKGFP
GPAGRGDLYLEVRITIPERLTPEEEALWKKLAEAYYARA

Specific function: Does not influence ATP binding or hydrolysis nor ADP release. Exerts influence on the interaction of dnaK with substrates; in the presence of dafA, dnaJ inhibits substrate binding, and substrate already bound to dnaK is displaced by dnaJ and dafA

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI201862587, Length=342, Percent_Identity=32.4561403508772, Blast_Score=141, Evalue=8e-34,
Organism=Homo sapiens, GI201862518, Length=342, Percent_Identity=32.4561403508772, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI56549115, Length=342, Percent_Identity=32.4561403508772, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI5453690, Length=324, Percent_Identity=32.7160493827161, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI6631085, Length=337, Percent_Identity=28.7833827893175, Blast_Score=134, Evalue=8e-32,
Organism=Homo sapiens, GI39204547, Length=315, Percent_Identity=31.1111111111111, Blast_Score=128, Evalue=5e-30,
Organism=Homo sapiens, GI7706495, Length=331, Percent_Identity=30.2114803625378, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI205360838, Length=110, Percent_Identity=49.0909090909091, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI205360840, Length=110, Percent_Identity=49.0909090909091, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI4504511, Length=171, Percent_Identity=38.0116959064327, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI194328760, Length=171, Percent_Identity=36.2573099415205, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI9558755, Length=121, Percent_Identity=45.4545454545455, Blast_Score=95, Evalue=7e-20,
Organism=Homo sapiens, GI194328758, Length=171, Percent_Identity=36.2573099415205, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI194306642, Length=105, Percent_Identity=48.5714285714286, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI194306640, Length=105, Percent_Identity=48.5714285714286, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI72534740, Length=116, Percent_Identity=40.5172413793103, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI56687498, Length=65, Percent_Identity=58.4615384615385, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI45504382, Length=65, Percent_Identity=55.3846153846154, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI47777312, Length=115, Percent_Identity=46.9565217391304, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI27151736, Length=107, Percent_Identity=47.6635514018692, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI22749377, Length=115, Percent_Identity=44.3478260869565, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI5031741, Length=69, Percent_Identity=56.5217391304348, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI88501736, Length=107, Percent_Identity=47.6635514018692, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4885495, Length=66, Percent_Identity=57.5757575757576, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI21553335, Length=68, Percent_Identity=57.3529411764706, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI17388799, Length=66, Percent_Identity=57.5757575757576, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI29126218, Length=65, Percent_Identity=55.3846153846154, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI217035105, Length=71, Percent_Identity=50.7042253521127, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI23503241, Length=104, Percent_Identity=40.3846153846154, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI68077168, Length=67, Percent_Identity=50.7462686567164, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI68077166, Length=67, Percent_Identity=50.7462686567164, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI24308127, Length=71, Percent_Identity=43.6619718309859, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1787235, Length=290, Percent_Identity=37.5862068965517, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1786197, Length=262, Percent_Identity=36.2595419847328, Blast_Score=121, Evalue=7e-29,
Organism=Caenorhabditis elegans, GI17534355, Length=321, Percent_Identity=31.4641744548287, Blast_Score=137, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17553098, Length=340, Percent_Identity=30.5882352941176, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17553096, Length=340, Percent_Identity=30.5882352941176, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI212645553, Length=321, Percent_Identity=29.595015576324, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17554644, Length=89, Percent_Identity=47.1910112359551, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17568643, Length=67, Percent_Identity=58.2089552238806, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17538236, Length=114, Percent_Identity=39.4736842105263, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI115532476, Length=71, Percent_Identity=50.7042253521127, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507263, Length=67, Percent_Identity=47.7611940298507, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17554900, Length=85, Percent_Identity=36.4705882352941, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17563890, Length=63, Percent_Identity=53.968253968254, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115532378, Length=71, Percent_Identity=43.6619718309859, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324265, Length=259, Percent_Identity=32.8185328185328, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6323870, Length=67, Percent_Identity=58.2089552238806, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323813, Length=67, Percent_Identity=55.2238805970149, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6322194, Length=110, Percent_Identity=40.9090909090909, Blast_Score=76, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6320888, Length=103, Percent_Identity=43.6893203883495, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323119, Length=156, Percent_Identity=33.974358974359, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324321, Length=70, Percent_Identity=47.1428571428571, Blast_Score=69, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6321094, Length=160, Percent_Identity=27.5, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324103, Length=87, Percent_Identity=41.3793103448276, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322388, Length=70, Percent_Identity=47.1428571428571, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6324252, Length=74, Percent_Identity=43.2432432432432, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI85726398, Length=351, Percent_Identity=30.4843304843305, Blast_Score=141, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24658562, Length=332, Percent_Identity=30.421686746988, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24658555, Length=332, Percent_Identity=30.421686746988, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI18858081, Length=343, Percent_Identity=28.2798833819242, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45549272, Length=69, Percent_Identity=62.3188405797101, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI45552813, Length=69, Percent_Identity=62.3188405797101, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI20129487, Length=145, Percent_Identity=42.0689655172414, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24584014, Length=145, Percent_Identity=42.0689655172414, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI45552811, Length=69, Percent_Identity=62.3188405797101, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24668492, Length=66, Percent_Identity=56.0606060606061, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641698, Length=64, Percent_Identity=60.9375, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24641696, Length=64, Percent_Identity=60.9375, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21358273, Length=70, Percent_Identity=57.1428571428571, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654066, Length=115, Percent_Identity=40.8695652173913, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654070, Length=115, Percent_Identity=40.8695652173913, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654068, Length=115, Percent_Identity=40.8695652173913, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24654072, Length=115, Percent_Identity=40.8695652173913, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17737735, Length=65, Percent_Identity=52.3076923076923, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28574723, Length=65, Percent_Identity=52.3076923076923, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI19920464, Length=69, Percent_Identity=50.7246376811594, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24668523, Length=65, Percent_Identity=52.3076923076923, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI161077138, Length=68, Percent_Identity=54.4117647058823, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646562, Length=70, Percent_Identity=54.2857142857143, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646560, Length=70, Percent_Identity=54.2857142857143, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646558, Length=70, Percent_Identity=54.2857142857143, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24646556, Length=70, Percent_Identity=54.2857142857143, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357547, Length=70, Percent_Identity=54.2857142857143, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17648033, Length=119, Percent_Identity=39.4957983193277, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24584630, Length=117, Percent_Identity=40.1709401709402, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI21357687, Length=64, Percent_Identity=50, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24643995, Length=63, Percent_Identity=49.2063492063492, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21355911, Length=83, Percent_Identity=43.3734939759036, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19922238, Length=70, Percent_Identity=44.2857142857143, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651436, Length=67, Percent_Identity=47.7611940298507, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24651439, Length=70, Percent_Identity=45.7142857142857, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21358311, Length=67, Percent_Identity=47.7611940298507, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DNAJ2_THET8 (Q56237)

Other databases:

- EMBL:   L57504
- EMBL:   Y07826
- EMBL:   D84222
- EMBL:   AB012390
- EMBL:   AB032368
- EMBL:   AP008226
- RefSeq:   YP_144755.1
- ProteinModelPortal:   Q56237
- STRING:   Q56237
- GeneID:   3170135
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA1489
- NMPDR:   fig|300852.3.peg.1801
- eggNOG:   COG2214
- HOGENOM:   HBG635315
- OMA:   GAERSIS
- ProtClustDB:   PRK14299
- BioCyc:   TTHE300852:TTHA1489-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01152
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- Gene3D:   G3DSA:1.10.287.110
- PANTHER:   PTHR11821
- PRINTS:   PR00625
- SMART:   SM00271

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; SSF46565 DnaJ_N; SSF49493 HSP40_DnaJ_pep

EC number: NA

Molecular weight: Translated: 30979; Mature: 30848

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKKDYYAILGVPRNATQEEIKRAYKRLARQYHPDVNKSPEAEEKFKEINEAYAVLSDP
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
EKRRIYDTYGTTEAPPPPPPGGYDFSGFDVEDFSEFFQELFGPGLFGGFGRRSRKGRDLR
HHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
AELPLTLEEAFHGGERVVEVAGRRVSVRIPPGVREGSVIRVPGMGGQGNPPGDLLLVVRL
ECCCEEHHHHHCCHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHH
LPHPVFRLEGQDLYATLDVPAPIAVVGGKVRAMTLEGPVEVAVPPRTQAGRKLRLKGKGF
HCCCEEEECCCCEEEEECCCCCEEEECCEEEEEEECCCEEEEECCCCCCCCEEEEECCCC
PGPAGRGDLYLEVRITIPERLTPEEEALWKKLAEAYYARA
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AAKKDYYAILGVPRNATQEEIKRAYKRLARQYHPDVNKSPEAEEKFKEINEAYAVLSDP
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCC
EKRRIYDTYGTTEAPPPPPPGGYDFSGFDVEDFSEFFQELFGPGLFGGFGRRSRKGRDLR
HHHEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCE
AELPLTLEEAFHGGERVVEVAGRRVSVRIPPGVREGSVIRVPGMGGQGNPPGDLLLVVRL
ECCCEEHHHHHCCHHHHHHHCCCEEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHH
LPHPVFRLEGQDLYATLDVPAPIAVVGGKVRAMTLEGPVEVAVPPRTQAGRKLRLKGKGF
HCCCEEEECCCCEEEEECCCCCEEEECCEEEEEEECCCEEEEECCCCCCCCEEEEECCCC
PGPAGRGDLYLEVRITIPERLTPEEEALWKKLAEAYYARA
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9349721; 9276481; 10092456