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The map label for this gene is speH [H]

Identifier: 55981426

GI number: 55981426

Start: 1384513

End: 1384956

Strand: Direct

Name: speH [H]

Synonym: TTHA1457

Alternate gene names: 55981426

Gene position: 1384513-1384956 (Clockwise)

Preceding gene: 55981421

Following gene: 55981427

Centisome position: 74.85

GC content: 63.51

Gene sequence:

>444_bases
GTGGTCTTGGTGGAACTCTTCGGCTTCGGTCCTCACCTGATGGTGGACGGCTACGAGGCGAACCCCGATCGCCTGCGGGA
CGCGGAGCTCATCCGCCGGGTTCTCAACGAGCTCCCTGAGGAGATGGAGATGACCAAGGTCCTTCCCCCCTTCGTCTACA
GCTACGGGCCCGGGGGCGAGGACGGGGTGACCGGCGTGGTCATCATCGCCGAAAGCCACATCGCCATCCACACCTTCCCC
AAGAAGCGCTTCCTTTCCGTGGACATCTTCTCCTGCAAGGCCTTTGACATGGCGAAGGCCCTGAAGAAGCTCGCCGAGGT
CTTTGAGATCCGGCGCTACGAGACCTACATGATCAACCGGGGCAAGGAGTTCCCCAAGGACCCCGAGCTCGCCCGCCAGA
TCGTCCTGGGCGAGCGGGAGTACCTGGAAGCCCGGGTGGGCTGA

Upstream 100 bases:

>100_bases
GGCTTTCCCGCTCTCCGACGGGGTCTTGACAGGGGGGGGAGGGGGGGGCATAATGGGGGGCGTGCCGTAGGGGGGATACC
CCGGGGGGCACGGAAAGGAG

Downstream 100 bases:

>100_bases
AGCCGCCCTCCTCTGGTCCCGGGAGCCCCCCGGGGCCTTTCATGTTTCCTTCATGCGCCTTCCCTAGCTTGAGGAGTGGA
GGCGTCTATGATGCGGAACG

Product: S-adenosylmethionine decarboxylase proenzyme

Products: NA

Alternate protein names: AdoMetDC; SAMDC [H]

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MVLVELFGFGPHLMVDGYEANPDRLRDAELIRRVLNELPEEMEMTKVLPPFVYSYGPGGEDGVTGVVIIAESHIAIHTFP
KKRFLSVDIFSCKAFDMAKALKKLAEVFEIRRYETYMINRGKEFPKDPELARQIVLGEREYLEARVG

Sequences:

>Translated_147_residues
MVLVELFGFGPHLMVDGYEANPDRLRDAELIRRVLNELPEEMEMTKVLPPFVYSYGPGGEDGVTGVVIIAESHIAIHTFP
KKRFLSVDIFSCKAFDMAKALKKLAEVFEIRRYETYMINRGKEFPKDPELARQIVLGEREYLEARVG
>Mature_147_residues
MVLVELFGFGPHLMVDGYEANPDRLRDAELIRRVLNELPEEMEMTKVLPPFVYSYGPGGEDGVTGVVIIAESHIAIHTFP
KKRFLSVDIFSCKAFDMAKALKKLAEVFEIRRYETYMINRGKEFPKDPELARQIVLGEREYLEARVG

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine [H]

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003826
- InterPro:   IPR016067
- InterPro:   IPR017716 [H]

Pfam domain/function: PF02675 AdoMet_dc [H]

EC number: =4.1.1.50 [H]

Molecular weight: Translated: 16823; Mature: 16823

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVELFGFGPHLMVDGYEANPDRLRDAELIRRVLNELPEEMEMTKVLPPFVYSYGPGGE
CEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHCCCCCCCC
DGVTGVVIIAESHIAIHTFPKKRFLSVDIFSCKAFDMAKALKKLAEVFEIRRYETYMINR
CCCEEEEEEECCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECC
GKEFPKDPELARQIVLGEREYLEARVG
CCCCCCCHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MVLVELFGFGPHLMVDGYEANPDRLRDAELIRRVLNELPEEMEMTKVLPPFVYSYGPGGE
CEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCCHHCCCCCCCC
DGVTGVVIIAESHIAIHTFPKKRFLSVDIFSCKAFDMAKALKKLAEVFEIRRYETYMINR
CCCEEEEEEECCCEEEEECCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEECC
GKEFPKDPELARQIVLGEREYLEARVG
CCCCCCCHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA