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The map label for this gene is lutB [H]

Identifier: 55981335

GI number: 55981335

Start: 1303431

End: 1304819

Strand: Direct

Name: lutB [H]

Synonym: TTHA1366

Alternate gene names: 55981335

Gene position: 1303431-1304819 (Clockwise)

Preceding gene: 55981334

Following gene: 55981336

Centisome position: 70.47

GC content: 69.69

Gene sequence:

>1389_bases
ATGCGGGCTAAGGCGAAGCTCTACCCCAAGGAAGCGGCAAGGCTCATCCGGGAAAAGCCCGGGGTGCGGGAGGCGGTCAC
CGGGGCCACCCTCCACTTTGAAAGGAACCGCCTCAAGGCCTACGCCGAGGTCCCCATTGAGGCGTGGCGGGAACGGGCCA
AGGCGGTGAAGGACCACGTCCTCACCCACCTGGACCACTACCTGGAGCTCGCGGAAAGGCGCCTTCGGGAAAACGGCGTC
CAGGTGCACTGGGCCGAGACCCCGGAGGACGCCCACCGGGTCTTAAGGGAGGTGGTGGCCCGGCACGGGGTGAAGCGGGC
GGTGAAGGCCAAGAGCATGCTCACCGAGGAGCTCGGGGTGAACCCCCTCCTCGAGGCCCTGGGGGTGGAGGTCTACGAGA
CGGACCTCGGGGAGTACCTGATCCAGCTTCTGGGCGAGCCCCCGAGCCACATCGTGGGCCCCGCCATCCACCTCTCCTTG
GAGGAGATCCAGAGGCTCTTCCACCAGCGCTTCGGCACCCCTTTGGACGCCCCCCCTGAGGCCCTGGCCCAGGTGGCCCG
CAAGGTGCTACGGGAGGCCTTCCTCACCGCCGAGCTCGGCATCAGCGGGGCCAACTTCCTGGTGGCGGAAACCGGCACCC
TGGCCCTCATGGAGAACGAGGGGAACATAAGGCTTTCCACCTCCCTCCCCAGGGTCCACGTGGCCTTCGTGGGGATAGAG
AAGCTTCTTCCCCGCTTCGCCGACCTCGCCCTCTTCCTCCCCCTCGCCGCCCGGGCGGCCACGGGGCAGCGCCTTTCCAC
CTTCGTCTCCCTCATCCAGGGCCCCGCCAGGGAGGGGGAGGAGGGCCCCCTGGAGGTCCACGTGGTCCTGGTGGACCACG
GGCGCACCGCCCTCCTCCATGACCCCGAGGCCTGGGAGACCCTGAGGTGCCTCCGCTGCGGGGCCTGCCTCAACGCCTGC
CCCGTCTACCGCCAGACCGGGGGGCACCCCTACGGCTACGTCTACTCCGGCCCCATCGGGGCGGTCCTGGACCCCGGGCT
CCTCACCCTGGAGGAGGCCTACCCCCTGCCCTACGCCTCCACCCTCTGCGGGGCCTGCCTGGAGGCCTGCCCGGTGAAGA
TCCCCATCCCCAAGCTCCTCCTCACCTGGCGGCACCGGGCGGTGGAGGAGGGCCTCACCCCCTCGTGGGAGCACGGGGCC
ATGCGGGCCTTCCGCAAGGTCATGGAAAGCCCCGCCCTCTACCGCCTCTTCTCCAAGGGCTTAAGGGGCCTTCCCCTCCC
CCAGGACCTCCTCCCCCTCCTTAAGGCCTGGACGGAGGGCAGGGGCCCCCTGAAGCCAAGCCCCAAGCCCTTCCACGAGC
TCTGGAAGGAGGTGGAGCGTGGAGGCTAG

Upstream 100 bases:

>100_bases
TCCACGGACGCGGGCTGCCTCCTCCACCTCGCGGGGCGCCTGGGCAAGAAGGGCGAGAACCTCAGGGTGGCCCCCCTCGC
CACCCTGCTCTGGGAGGCGT

Downstream 100 bases:

>100_bases
GACCAGGATCCTCGCCCGGGTGCAGCGGGCCCTAAAGGAGCGCCCCAAGGCCCTCCTCCCCGAGCACCCCCACACCCCCC
TTCACGAGGACCCCGTGGAC

Product: iron-sulfur protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MRAKAKLYPKEAARLIREKPGVREAVTGATLHFERNRLKAYAEVPIEAWRERAKAVKDHVLTHLDHYLELAERRLRENGV
QVHWAETPEDAHRVLREVVARHGVKRAVKAKSMLTEELGVNPLLEALGVEVYETDLGEYLIQLLGEPPSHIVGPAIHLSL
EEIQRLFHQRFGTPLDAPPEALAQVARKVLREAFLTAELGISGANFLVAETGTLALMENEGNIRLSTSLPRVHVAFVGIE
KLLPRFADLALFLPLAARAATGQRLSTFVSLIQGPAREGEEGPLEVHVVLVDHGRTALLHDPEAWETLRCLRCGACLNAC
PVYRQTGGHPYGYVYSGPIGAVLDPGLLTLEEAYPLPYASTLCGACLEACPVKIPIPKLLLTWRHRAVEEGLTPSWEHGA
MRAFRKVMESPALYRLFSKGLRGLPLPQDLLPLLKAWTEGRGPLKPSPKPFHELWKEVERGG

Sequences:

>Translated_462_residues
MRAKAKLYPKEAARLIREKPGVREAVTGATLHFERNRLKAYAEVPIEAWRERAKAVKDHVLTHLDHYLELAERRLRENGV
QVHWAETPEDAHRVLREVVARHGVKRAVKAKSMLTEELGVNPLLEALGVEVYETDLGEYLIQLLGEPPSHIVGPAIHLSL
EEIQRLFHQRFGTPLDAPPEALAQVARKVLREAFLTAELGISGANFLVAETGTLALMENEGNIRLSTSLPRVHVAFVGIE
KLLPRFADLALFLPLAARAATGQRLSTFVSLIQGPAREGEEGPLEVHVVLVDHGRTALLHDPEAWETLRCLRCGACLNAC
PVYRQTGGHPYGYVYSGPIGAVLDPGLLTLEEAYPLPYASTLCGACLEACPVKIPIPKLLLTWRHRAVEEGLTPSWEHGA
MRAFRKVMESPALYRLFSKGLRGLPLPQDLLPLLKAWTEGRGPLKPSPKPFHELWKEVERGG
>Mature_462_residues
MRAKAKLYPKEAARLIREKPGVREAVTGATLHFERNRLKAYAEVPIEAWRERAKAVKDHVLTHLDHYLELAERRLRENGV
QVHWAETPEDAHRVLREVVARHGVKRAVKAKSMLTEELGVNPLLEALGVEVYETDLGEYLIQLLGEPPSHIVGPAIHLSL
EEIQRLFHQRFGTPLDAPPEALAQVARKVLREAFLTAELGISGANFLVAETGTLALMENEGNIRLSTSLPRVHVAFVGIE
KLLPRFADLALFLPLAARAATGQRLSTFVSLIQGPAREGEEGPLEVHVVLVDHGRTALLHDPEAWETLRCLRCGACLNAC
PVYRQTGGHPYGYVYSGPIGAVLDPGLLTLEEAYPLPYASTLCGACLEACPVKIPIPKLLLTWRHRAVEEGLTPSWEHGA
MRAFRKVMESPALYRLFSKGLRGLPLPQDLLPLLKAWTEGRGPLKPSPKPFHELWKEVERGG

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=401, Percent_Identity=44.6384039900249, Blast_Score=365, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 51276; Mature: 51276

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAKAKLYPKEAARLIREKPGVREAVTGATLHFERNRLKAYAEVPIEAWRERAKAVKDHV
CCCCCCCCHHHHHHHHHHCCCHHHHHCCHHEEEHHHHHHHHHHCCHHHHHHHHHHHHHHH
LTHLDHYLELAERRLRENGVQVHWAETPEDAHRVLREVVARHGVKRAVKAKSMLTEELGV
HHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPLLEALGVEVYETDLGEYLIQLLGEPPSHIVGPAIHLSLEEIQRLFHQRFGTPLDAPPE
CHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHH
ALAQVARKVLREAFLTAELGISGANFLVAETGTLALMENEGNIRLSTSLPRVHVAFVGIE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCEEEECCCCCHHHHHHHHH
KLLPRFADLALFLPLAARAATGQRLSTFVSLIQGPAREGEEGPLEVHVVLVDHGRTALLH
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCEEEEC
DPEAWETLRCLRCGACLNACPVYRQTGGHPYGYVYSGPIGAVLDPGLLTLEEAYPLPYAS
CCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCCHHCCCCEEHHHCCCCCHHH
TLCGACLEACPVKIPIPKLLLTWRHRAVEEGLTPSWEHGAMRAFRKVMESPALYRLFSKG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHC
LRGLPLPQDLLPLLKAWTEGRGPLKPSPKPFHELWKEVERGG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MRAKAKLYPKEAARLIREKPGVREAVTGATLHFERNRLKAYAEVPIEAWRERAKAVKDHV
CCCCCCCCHHHHHHHHHHCCCHHHHHCCHHEEEHHHHHHHHHHCCHHHHHHHHHHHHHHH
LTHLDHYLELAERRLRENGVQVHWAETPEDAHRVLREVVARHGVKRAVKAKSMLTEELGV
HHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPLLEALGVEVYETDLGEYLIQLLGEPPSHIVGPAIHLSLEEIQRLFHQRFGTPLDAPPE
CHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHH
ALAQVARKVLREAFLTAELGISGANFLVAETGTLALMENEGNIRLSTSLPRVHVAFVGIE
HHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCEEEEEECCCCEEEECCCCCHHHHHHHHH
KLLPRFADLALFLPLAARAATGQRLSTFVSLIQGPAREGEEGPLEVHVVLVDHGRTALLH
HHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCEEEEC
DPEAWETLRCLRCGACLNACPVYRQTGGHPYGYVYSGPIGAVLDPGLLTLEEAYPLPYAS
CCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCCHHCCCCEEHHHCCCCCHHH
TLCGACLEACPVKIPIPKLLLTWRHRAVEEGLTPSWEHGAMRAFRKVMESPALYRLFSKG
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCHHHHHHHHHC
LRGLPLPQDLLPLLKAWTEGRGPLKPSPKPFHELWKEVERGG
CCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA