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The map label for this gene is tagO [H]

Identifier: 55981282

GI number: 55981282

Start: 1251405

End: 1252505

Strand: Direct

Name: tagO [H]

Synonym: TTHA1313

Alternate gene names: 55981282

Gene position: 1251405-1252505 (Clockwise)

Preceding gene: 55981281

Following gene: 55981283

Centisome position: 67.65

GC content: 68.94

Gene sequence:

>1101_bases
ATGGCACCAAGTGACCTGCTGGAGTTCCTCCACCGCCTGGGCGTGGCCAACCCCTACGGGCGGGGCTGGCTCACCGTCCT
CCTCGTCTTTTTCCTGGCCCTCCTCTTCACCTGGCGCTTCCTGCCCCACGTGCGCCGCTTCGCCCTGAAGGTGGGCTGGG
CCGACCTGCCCAACGAGCGCAGGCTCAACCGGGAGCCCCTCCCCAACGCCGGGGGGCTCGCCCTCTACGCCGGGGTGGTG
CTCGCCCTGGTGGTGGCGGCCTTCCTCCGGCCCATCCTGGTGGAGCAGGTGCTCATCCAGGTCCTCGCCATCCTCCTGGG
GGGAGCCTGGCTCGTGCTTGTGGGCTTCATTGACGACCAGTTCGGCCTTCCTCCCCTCTTCCGCCTCTTCGTCCAGACGC
TTTCCGCCCTCCTCCTCGTGGCCGTGGGGGTGCGGTTTGAGGCCGCCTTCGGCACCCCCTTGGACCCCGCCTTGGGACTC
TTCCTCACCTGGCTTTGGGTCGTGGGCATCACCAATGCCCTCAACCTCATGGACGGCCTGGACGGCCTCGCCGGGGGGAT
CGCCTTCATCAGCGCCATGAGCCTCCTCTTCGTCTCCGCCCAGTTCCCCTACTGGGCGGCAGGGACGCTGGTGCTTTCCG
CCCTGGCGGGGGCCTCCTTGGGCTTCCTCCGGCACAACCTCCACCCAAGCCGCATCATCCTGGGGGACGCGGGGGCCTAC
TTCCTGGGCTACACCTTGGCCGCCACCGCCCTCCTCGGCAACCTCAAGCTCACCACCTTCCTGGGCCTCCTCCCCCCGGC
GCTCTTCCTCCTCCTCCCCATCCTGGACACCACCCAGGTGGTGGTGCGGAGGCTCCTCAGGGGGCAGAACCCCCTCTCCA
CCCCCGGCAAGGACCACATCCACCACCGCCTCCTGGCCCGGGGGCTTTCCCAAAGGCGGGTGGCCTTCCTCCTCTGGGGG
GCGGCCCTCCTCTTCAACCTCCTCGCCATGGTCTACCTGGGAATGCCCTGGGAGGCCATCCTGACGAGCCTTCTCGCCAC
CGCCCTGGGCCTCGCCTGGGTCACCTACCGGAGGCTTAGGGCGCTATGGAGGGGGGAATGA

Upstream 100 bases:

>100_bases
GACCACCCCGACACCGAGGTGGTGGTGGCGGCCATAGACGAGCGCCTCAACGACCACGGCTACATCGTCCCCGGCCTCGG
CGACGCCGGGGACCGGATCT

Downstream 100 bases:

>100_bases
AACGCGTGGTCCTCGCCTTCGGCACGCGGCCCGAGGCCACCAAGATGGCCCCCGTGTACCTGGCCCTCAGGGGGATCCCG
GGCCTGAAGCCCCTCGTCCT

Product: hypothetical protein

Products: UMP; Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MAPSDLLEFLHRLGVANPYGRGWLTVLLVFFLALLFTWRFLPHVRRFALKVGWADLPNERRLNREPLPNAGGLALYAGVV
LALVVAAFLRPILVEQVLIQVLAILLGGAWLVLVGFIDDQFGLPPLFRLFVQTLSALLLVAVGVRFEAAFGTPLDPALGL
FLTWLWVVGITNALNLMDGLDGLAGGIAFISAMSLLFVSAQFPYWAAGTLVLSALAGASLGFLRHNLHPSRIILGDAGAY
FLGYTLAATALLGNLKLTTFLGLLPPALFLLLPILDTTQVVVRRLLRGQNPLSTPGKDHIHHRLLARGLSQRRVAFLLWG
AALLFNLLAMVYLGMPWEAILTSLLATALGLAWVTYRRLRALWRGE

Sequences:

>Translated_366_residues
MAPSDLLEFLHRLGVANPYGRGWLTVLLVFFLALLFTWRFLPHVRRFALKVGWADLPNERRLNREPLPNAGGLALYAGVV
LALVVAAFLRPILVEQVLIQVLAILLGGAWLVLVGFIDDQFGLPPLFRLFVQTLSALLLVAVGVRFEAAFGTPLDPALGL
FLTWLWVVGITNALNLMDGLDGLAGGIAFISAMSLLFVSAQFPYWAAGTLVLSALAGASLGFLRHNLHPSRIILGDAGAY
FLGYTLAATALLGNLKLTTFLGLLPPALFLLLPILDTTQVVVRRLLRGQNPLSTPGKDHIHHRLLARGLSQRRVAFLLWG
AALLFNLLAMVYLGMPWEAILTSLLATALGLAWVTYRRLRALWRGE
>Mature_365_residues
APSDLLEFLHRLGVANPYGRGWLTVLLVFFLALLFTWRFLPHVRRFALKVGWADLPNERRLNREPLPNAGGLALYAGVVL
ALVVAAFLRPILVEQVLIQVLAILLGGAWLVLVGFIDDQFGLPPLFRLFVQTLSALLLVAVGVRFEAAFGTPLDPALGLF
LTWLWVVGITNALNLMDGLDGLAGGIAFISAMSLLFVSAQFPYWAAGTLVLSALAGASLGFLRHNLHPSRIILGDAGAYF
LGYTLAATALLGNLKLTTFLGLLPPALFLLLPILDTTQVVVRRLLRGQNPLSTPGKDHIHHRLLARGLSQRRVAFLLWGA
ALLFNLLAMVYLGMPWEAILTSLLATALGLAWVTYRRLRALWRGE

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

Organism=Homo sapiens, GI42794009, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1790218, Length=289, Percent_Identity=27.681660899654, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786275, Length=352, Percent_Identity=27.8409090909091, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 40018; Mature: 39887

Theoretical pI: Translated: 11.04; Mature: 11.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPSDLLEFLHRLGVANPYGRGWLTVLLVFFLALLFTWRFLPHVRRFALKVGWADLPNER
CCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RLNREPLPNAGGLALYAGVVLALVVAAFLRPILVEQVLIQVLAILLGGAWLVLVGFIDDQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
FGLPPLFRLFVQTLSALLLVAVGVRFEAAFGTPLDPALGLFLTWLWVVGITNALNLMDGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DGLAGGIAFISAMSLLFVSAQFPYWAAGTLVLSALAGASLGFLRHNLHPSRIILGDAGAY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
FLGYTLAATALLGNLKLTTFLGLLPPALFLLLPILDTTQVVVRRLLRGQNPLSTPGKDHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHH
HHRLLARGLSQRRVAFLLWGAALLFNLLAMVYLGMPWEAILTSLLATALGLAWVTYRRLR
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALWRGE
HHHCCC
>Mature Secondary Structure 
APSDLLEFLHRLGVANPYGRGWLTVLLVFFLALLFTWRFLPHVRRFALKVGWADLPNER
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
RLNREPLPNAGGLALYAGVVLALVVAAFLRPILVEQVLIQVLAILLGGAWLVLVGFIDDQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCC
FGLPPLFRLFVQTLSALLLVAVGVRFEAAFGTPLDPALGLFLTWLWVVGITNALNLMDGL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DGLAGGIAFISAMSLLFVSAQFPYWAAGTLVLSALAGASLGFLRHNLHPSRIILGDAGAY
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHH
FLGYTLAATALLGNLKLTTFLGLLPPALFLLLPILDTTQVVVRRLLRGQNPLSTPGKDHI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCHHHH
HHRLLARGLSQRRVAFLLWGAALLFNLLAMVYLGMPWEAILTSLLATALGLAWVTYRRLR
HHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ALWRGE
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-N-Acetyl-D-Glucosamine; Undecaprenyl Phosphate [C]

Specific reaction: UDP-N-Acetyl-D-Glucosamine + Undecaprenyl Phosphate = UMP + Undecaprenyl N-Acetyl-Alpha-D-Glucosaminyl Pyrophosphate. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]