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The map label for this gene is 55981252

Identifier: 55981252

GI number: 55981252

Start: 1222960

End: 1223634

Strand: Direct

Name: 55981252

Synonym: TTHA1283

Alternate gene names: NA

Gene position: 1222960-1223634 (Clockwise)

Preceding gene: 55981251

Following gene: 55981253

Centisome position: 66.12

GC content: 67.26

Gene sequence:

>675_bases
ATGGTGGAGGTTCGGTATCTCGGCCACTCGGCGGTCCTCCTCACGGACGGCAAGACGCGGATCGTCATAGACCCCTTCCT
CACCGGAAACCCCATGGCCGCCCTCGGGGTGGGGGAGGTCCAGGCGGACCTCATCCTGGTCACCCACGCCCACGGGGACC
ACTTCGGGGACAGCGTGGCCCTCTCCAAGAAGGGAGGCGTGGTGGTCTCCACCTTTGAGATCGCCACCTACGCCGAGAAG
CACGGGGCGAAGAGCGTCCCCATGAACCTGGGGGGCACCTACCGCTTTGAGGGCGGCTGGCTCAAGTGGGTGCCCGCCTG
GCACTCCAGTAGCTTCCCCGACGGCACCTACGGTGGCATGCCCATGGGCGTGGTGGTGGAGCTTGGGGGCAAGCGCATCT
ACCACGCCGGGGACACCGCCCTCTTCTCCGACATGCGCCTCATCGGGGAGATGGGCCTGGACCTCGCCCTCCTCCCCATC
GGCGACCACTTCACCATGGGCCCCGAGGACGCCCTGAAGGCCCTGGAGCTCCTCAGGCCCAAGAAGGTGGTGCCCATCCA
CTACAACACCTTCCCCCCCATCCGCCAAGACGGGGAGGCCTTCGCCCAACGGGCCAGGGAGAAGGGCGTGGAGGGGCATG
CCCTAAAGCCGGGAGAGGTTCTCCGCCTTGACTAG

Upstream 100 bases:

>100_bases
CAGGATCTTGGAGGCCCTCTTCGCCAAGGCCCTGGAGGAAAGCCTTCCCGCGGGAGCGCGGCCTCCGTTATAGTGGGCCT
GAAGAAGCAGGAGGTGGCGT

Downstream 100 bases:

>100_bases
GAGGGACTTCCGGCTGGAGATGCTTTTGGGCCTGGGCCAGACGGCCCAGGTCCACCTGGCCCGGGCCCCCGACGGGACGC
GGGTGGCCCTGAAGATCCCG

Product: metal-dependent hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MVEVRYLGHSAVLLTDGKTRIVIDPFLTGNPMAALGVGEVQADLILVTHAHGDHFGDSVALSKKGGVVVSTFEIATYAEK
HGAKSVPMNLGGTYRFEGGWLKWVPAWHSSSFPDGTYGGMPMGVVVELGGKRIYHAGDTALFSDMRLIGEMGLDLALLPI
GDHFTMGPEDALKALELLRPKKVVPIHYNTFPPIRQDGEAFAQRAREKGVEGHALKPGEVLRLD

Sequences:

>Translated_224_residues
MVEVRYLGHSAVLLTDGKTRIVIDPFLTGNPMAALGVGEVQADLILVTHAHGDHFGDSVALSKKGGVVVSTFEIATYAEK
HGAKSVPMNLGGTYRFEGGWLKWVPAWHSSSFPDGTYGGMPMGVVVELGGKRIYHAGDTALFSDMRLIGEMGLDLALLPI
GDHFTMGPEDALKALELLRPKKVVPIHYNTFPPIRQDGEAFAQRAREKGVEGHALKPGEVLRLD
>Mature_224_residues
MVEVRYLGHSAVLLTDGKTRIVIDPFLTGNPMAALGVGEVQADLILVTHAHGDHFGDSVALSKKGGVVVSTFEIATYAEK
HGAKSVPMNLGGTYRFEGGWLKWVPAWHSSSFPDGTYGGMPMGVVVELGGKRIYHAGDTALFSDMRLIGEMGLDLALLPI
GDHFTMGPEDALKALELLRPKKVVPIHYNTFPPIRQDGEAFAQRAREKGVEGHALKPGEVLRLD

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0173 family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1283_THET8 (Q5SIT1)

Other databases:

- EMBL:   AP008226
- RefSeq:   YP_144549.1
- ProteinModelPortal:   Q5SIT1
- STRING:   Q5SIT1
- GeneID:   3169078
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA1283
- eggNOG:   COG2220
- HOGENOM:   HBG741314
- OMA:   VILLTHG
- ProtClustDB:   PRK00685
- BioCyc:   TTHE300852:TTHA1283-MONOMER
- HAMAP:   MF_00457
- InterPro:   IPR001279
- InterPro:   IPR022877
- SMART:   SM00849

Pfam domain/function: PF00753 Lactamase_B

EC number: NA

Molecular weight: Translated: 24183; Mature: 24183

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEVRYLGHSAVLLTDGKTRIVIDPFLTGNPMAALGVGEVQADLILVTHAHGDHFGDSVA
CEEEEEECCEEEEEECCCEEEEECCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCEEE
LSKKGGVVVSTFEIATYAEKHGAKSVPMNLGGTYRFEGGWLKWVPAWHSSSFPDGTYGGM
EECCCCEEEEEEEEEHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCC
PMGVVVELGGKRIYHAGDTALFSDMRLIGEMGLDLALLPIGDHFTMGPEDALKALELLRP
CEEEEEEECCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
KKVVPIHYNTFPPIRQDGEAFAQRAREKGVEGHALKPGEVLRLD
CEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MVEVRYLGHSAVLLTDGKTRIVIDPFLTGNPMAALGVGEVQADLILVTHAHGDHFGDSVA
CEEEEEECCEEEEEECCCEEEEECCCCCCCCEEEEECCCEEEEEEEEEECCCCCCCCEEE
LSKKGGVVVSTFEIATYAEKHGAKSVPMNLGGTYRFEGGWLKWVPAWHSSSFPDGTYGGM
EECCCCEEEEEEEEEHHHHHCCCCCCCCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCC
PMGVVVELGGKRIYHAGDTALFSDMRLIGEMGLDLALLPIGDHFTMGPEDALKALELLRP
CEEEEEEECCCEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHCC
KKVVPIHYNTFPPIRQDGEAFAQRAREKGVEGHALKPGEVLRLD
CEEEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA