The gene/protein map for NC_007519 is currently unavailable.
Definition Thermus thermophilus HB8 chromosome, complete genome.
Accession NC_006461
Length 1,849,742

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The map label for this gene is atpB

Identifier: 55981241

GI number: 55981241

Start: 1213415

End: 1214851

Strand: Reverse

Name: atpB

Synonym: TTHA1272

Alternate gene names: 55981241

Gene position: 1214851-1213415 (Counterclockwise)

Preceding gene: 55981242

Following gene: 55981240

Centisome position: 65.68

GC content: 65.83

Gene sequence:

>1437_bases
ATGGACCTTCTGAAGAAGGAGTACACGGGCATCACCTACATCTCGGGGCCTCTTCTCTTCGTGGAGAACGCCAAGGACCT
GGCCTACGGGGCCATCGTGGACATCAAGGACGGCACGGGCCGGGTCCGCGGCGGCCAGGTGATTGAGGTCTCCGAGGAGT
ACGCCGTCATCCAGGTGTTTGAGGAAACCACTGGGCTGGACCTGGCCACGACCAGCGTGAGCCTGGTGGAGGACGTGGCC
CGGCTTGGGGTCTCCAAGGAGATGCTGGGCCGCCGCTTCAACGGCATCGGCAAGCCCATAGACGGCCTGCCGCCCATCAC
CCCGGAGAAGCGGCTCCCCATCACCGGCCTTCCCTTAAACCCCGTGGCCCGGAGGAAGCCGGAGCAGTTCATCCAGACGG
GCATCTCCACCATTGACGTGATGAACACCCTGGTCCGGGGGCAGAAGCTTCCCATCTTCTCCGGCTCGGGGCTTCCCGCC
AACGAGATCGCCGCCCAGATCGCCCGCCAGGCCACGGTGCGCCCCGACCTCTCCGGGGAGGGGGAGAAGGAGGAGCCCTT
CGCCGTGGTCTTCGCCGCCATGGGGATCACGCAGCGGGAGCTCTCCTACTTCATCCAGGAGTTTGAGCGCACCGGGGCCC
TGAGCCGCTCCGTCCTCTTCCTGAACAAGGCGGACGACCCCACCATTGAGCGCATCCTCACCCCCCGCATGGCCCTCACC
GTGGCCGAGTACCTGGCCTTTGAGCACGACTACCACGTCCTCGTCATCCTCACGGACATGACCAACTACTGCGAGGCCTT
GCGGGAGATCGGGGCCGCCCGCGAGGAGATCCCGGGCCGCCGCGGTTACCCCGGCTACATGTACACCGACCTGGCCACCA
TCTACGAGCGCGCCGGGGTGGTGGAGGGGAAGAAGGGGAGCGTGACCCAGATCCCCATCCTCTCCATGCCCGACGACGAC
CGCACCCACCCCATCCCCGACCTCACGGGCTACATCACCGAGGGGCAGATCCAGCTCTCCCGGGAGCTCCACCGCAAGGG
CATCTACCCGCCCATTGACCCCTTGCCCTCCCTCTCCCGGCTCATGAACAACGGCGTGGGCAAGGGCAAGACCCGGGAGG
ACCACAAGCAGGTCTCCGACCAGCTCTACTCCGCCTACGCCAACGGGGTGGACATCCGGAAGCTCGTGGCCATCATCGGC
GAGGACGCCCTCACGGAGAACGACCGCCGTTACCTCCAGTTCGCCGACGCCTTTGAACGGTTCTTCATCAACCAGGGGCA
GCAGAACCGCTCCATTGAGGAGAGCCTGCAGATCGCCTGGGCCCTCCTCTCCATGCTGCCCCAGGGCGAGCTCAAGCGCA
TCTCCAAGGACCACATCGGCAAGTACTACGGCCAGAAGCTGGAGGAGATCTGGGGCGCGCCCCAGGCCCTGGACTAA

Upstream 100 bases:

>100_bases
CGCGCCCGCTACGTGAGCGAGGAGGAGTTCCCCGCCTACTTTGAGGAGGCCATGAAGGAGATCCAGGGGGCCTTCAAGGC
CCTGGCCTAAAGGGGGAGAG

Downstream 100 bases:

>100_bases
GGGAGGGTAGATGAGCCAGGTGAGCCCCACCCGGATGAACCTTCTGCAGAGGCGGGGGCAGCTCCGCCTGGCGCAGAAGG
GGGTGGACCTCCTCAAGAAG

Product: V-type ATP synthase subunit B

Products: ATP; H+; H2O [C]

Alternate protein names: V-ATPase subunit B

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MDLLKKEYTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVFEETTGLDLATTSVSLVEDVA
RLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLNPVARRKPEQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPA
NEIAAQIARQATVRPDLSGEGEKEEPFAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALT
VAEYLAFEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGVVEGKKGSVTQIPILSMPDDD
RTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSRLMNNGVGKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIG
EDALTENDRRYLQFADAFERFFINQGQQNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYYGQKLEEIWGAPQALD

Sequences:

>Translated_478_residues
MDLLKKEYTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVFEETTGLDLATTSVSLVEDVA
RLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLNPVARRKPEQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPA
NEIAAQIARQATVRPDLSGEGEKEEPFAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALT
VAEYLAFEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGVVEGKKGSVTQIPILSMPDDD
RTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSRLMNNGVGKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIG
EDALTENDRRYLQFADAFERFFINQGQQNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYYGQKLEEIWGAPQALD
>Mature_478_residues
MDLLKKEYTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVFEETTGLDLATTSVSLVEDVA
RLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLNPVARRKPEQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPA
NEIAAQIARQATVRPDLSGEGEKEEPFAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALT
VAEYLAFEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGVVEGKKGSVTQIPILSMPDDD
RTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSRLMNNGVGKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIG
EDALTENDRRYLQFADAFERFFINQGQQNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYYGQKLEEIWGAPQALD

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit

COG id: COG1156

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit B

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI19913428, Length=458, Percent_Identity=55.8951965065502, Blast_Score=517, Evalue=1e-146,
Organism=Homo sapiens, GI19913426, Length=461, Percent_Identity=54.880694143167, Blast_Score=513, Evalue=1e-145,
Organism=Homo sapiens, GI32189394, Length=349, Percent_Identity=28.3667621776504, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI50345984, Length=470, Percent_Identity=25.1063829787234, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4757810, Length=470, Percent_Identity=25.1063829787234, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI19913424, Length=323, Percent_Identity=22.6006191950464, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1788251, Length=284, Percent_Identity=34.1549295774648, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1790170, Length=408, Percent_Identity=25.2450980392157, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1790172, Length=389, Percent_Identity=25.9640102827763, Blast_Score=107, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17510931, Length=463, Percent_Identity=56.1555075593952, Blast_Score=524, Evalue=1e-149,
Organism=Caenorhabditis elegans, GI17570191, Length=457, Percent_Identity=56.2363238512035, Blast_Score=522, Evalue=1e-148,
Organism=Caenorhabditis elegans, GI25144756, Length=394, Percent_Identity=26.6497461928934, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71988080, Length=472, Percent_Identity=24.1525423728814, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988063, Length=472, Percent_Identity=24.1525423728814, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71988074, Length=455, Percent_Identity=23.956043956044, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17565854, Length=253, Percent_Identity=25.6916996047431, Blast_Score=81, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6319603, Length=458, Percent_Identity=55.4585152838428, Blast_Score=516, Evalue=1e-147,
Organism=Saccharomyces cerevisiae, GI6322581, Length=344, Percent_Identity=28.7790697674419, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6319370, Length=372, Percent_Identity=26.6129032258064, Blast_Score=100, Evalue=7e-22,
Organism=Saccharomyces cerevisiae, GI6320016, Length=274, Percent_Identity=25.9124087591241, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281361666, Length=459, Percent_Identity=55.9912854030501, Blast_Score=526, Evalue=1e-149,
Organism=Drosophila melanogaster, GI24646341, Length=459, Percent_Identity=55.9912854030501, Blast_Score=526, Evalue=1e-149,
Organism=Drosophila melanogaster, GI17136796, Length=459, Percent_Identity=55.9912854030501, Blast_Score=526, Evalue=1e-149,
Organism=Drosophila melanogaster, GI24638766, Length=349, Percent_Identity=28.080229226361, Blast_Score=127, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28574560, Length=355, Percent_Identity=26.1971830985915, Blast_Score=111, Evalue=8e-25,
Organism=Drosophila melanogaster, GI24658560, Length=484, Percent_Identity=24.3801652892562, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI20129479, Length=260, Percent_Identity=26.1538461538462, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583992, Length=252, Percent_Identity=25, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24583988, Length=252, Percent_Identity=24.6031746031746, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583986, Length=252, Percent_Identity=24.6031746031746, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583984, Length=252, Percent_Identity=24.6031746031746, Blast_Score=79, Evalue=6e-15,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): VATB_THET2 (Q72J73)

Other databases:

- EMBL:   AE017221
- RefSeq:   YP_004877.1
- ProteinModelPortal:   Q72J73
- SMR:   Q72J73
- STRING:   Q72J73
- GeneID:   2775518
- GenomeReviews:   AE017221_GR
- eggNOG:   COG1156
- HOGENOM:   HBG565875
- OMA:   RQAKVRG
- PhylomeDB:   Q72J73
- ProtClustDB:   PRK04196
- BioCyc:   TTHE262724:TT_C0906-MONOMER
- HAMAP:   MF_00310
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022879

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C

EC number: 3.6.3.14 [C]

Molecular weight: Translated: 53160; Mature: 53160

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MDLLKKEYTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVF
CCCHHHHCCCEEEECCCEEEEECCCCCEEEEEEEECCCCCCCCCCEEEEECCCEEEEEEE
EETTGLDLATTSVSLVEDVARLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLN
HHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PVARRKPEQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPANEIAAQIARQATVRPDLSGE
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCC
GEKEEPFAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALT
CCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCHHHHHH
VAEYLAFEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGV
HHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
VEGKKGSVTQIPILSMPDDDRTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSR
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCCHHHHH
LMNNGVGKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIGEDALTENDRRYLQFADAFER
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHH
FFINQGQQNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYYGQKLEEIWGAPQALD
HHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDLLKKEYTGITYISGPLLFVENAKDLAYGAIVDIKDGTGRVRGGQVIEVSEEYAVIQVF
CCCHHHHCCCEEEECCCEEEEECCCCCEEEEEEEECCCCCCCCCCEEEEECCCEEEEEEE
EETTGLDLATTSVSLVEDVARLGVSKEMLGRRFNGIGKPIDGLPPITPEKRLPITGLPLN
HHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
PVARRKPEQFIQTGISTIDVMNTLVRGQKLPIFSGSGLPANEIAAQIARQATVRPDLSGE
HHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCCCCCCCCC
GEKEEPFAVVFAAMGITQRELSYFIQEFERTGALSRSVLFLNKADDPTIERILTPRMALT
CCCCCCCEEHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHCHHHHHH
VAEYLAFEHDYHVLVILTDMTNYCEALREIGAAREEIPGRRGYPGYMYTDLATIYERAGV
HHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCC
VEGKKGSVTQIPILSMPDDDRTHPIPDLTGYITEGQIQLSRELHRKGIYPPIDPLPSLSR
CCCCCCCEEEEEEEECCCCCCCCCCCCCCCCEECCHHHHHHHHHHCCCCCCCCCCHHHHH
LMNNGVGKGKTREDHKQVSDQLYSAYANGVDIRKLVAIIGEDALTENDRRYLQFADAFER
HHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCCHHHHHHHHHHHH
FFINQGQQNRSIEESLQIAWALLSMLPQGELKRISKDHIGKYYGQKLEEIWGAPQALD
HHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Borate; Diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ADP; H+; Phosphate [C]

Specific reaction: ADP + (4) H+ + Phosphate <==> ATP + (3) H+ + H2O [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines various reactions catalyzed by ATPase, analogs; Oligomycin; Quercetin; Trialkyl tinderivatives; Venturicidin [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA