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The map label for this gene is ymxG [H]

Identifier: 55981233

GI number: 55981233

Start: 1204902

End: 1206122

Strand: Reverse

Name: ymxG [H]

Synonym: TTHA1264

Alternate gene names: 55981233

Gene position: 1206122-1204902 (Counterclockwise)

Preceding gene: 55981234

Following gene: 55981232

Centisome position: 65.2

GC content: 69.53

Gene sequence:

>1221_bases
ATGTTTAGGGAAGCCGAGCTGAGGAACGGCCTTCGGGTCATCGCCGAGGTGGTTCCGGGGGCGCGGAGCGTGGCCCTGGG
CTACTTCGTGAAGACGGGGGCCCGGGACGAGACCAAGGAGGAGAGCGGGGTGAGCCACTTCCTGGAGCACATGGTCTTCA
AGGGCCCCGAGGACATGGACGCCCTCGCCGTGAACCGGGCCTTTGACCGGATGGGGGCCCAGTACAACGCCTTCACCTCC
GAGGAGGCCACCGTCTACTACGGGGCGGTCCTCCCCGAGTTCGCCTACGACCTCCTCGGCCTCTTCGCCAAGCTCCTCCG
CCCCGCCCTCCGGGAGGAGGACTTCCAGACGGAGAAGCTGGTGATCCTGGAGGAGATCGCCCGCTACCAGGACCGCCCGG
GCTTCATGGCCTACGAGTGGGCCCGCGCCCGCTTCTTCCAGGGGCACCCCTTGGGGAATAGCGTCCTGGGGACGCGGGAG
AGCATCACCGCCCTCACCCGGGAAGGGATGGCGGCCTACCACCGGAGGCGCTACCTGCCCAAGAACATGGTCCTCGCCGC
CACAGGGCGGGTGGACTTTGACCGCCTCCTCGCCGAGGCCGAGCGCCTCACCGAGGCCTGGCCCGAGGGCGAGGCGGAAA
GGGCCTACCCGCCCTTAACGCCTGCCTTCGGGGTGGAGGAGCGCCCCTACGAGAAGGCCCGGGCCCTCTACCTGGTGGCC
CTCTTCCCGGGGGTCGCCTACCAGGAGGAGGCCCGCTTCCCCGGCCAGGTCCTCGCCCACCTCCTGGGGGAGGAGGGCTC
GGGCCGGCTCCACTTCGCCCTGGTGGACAAAGGCCTCGCCGAGGTGGCCTCCTTCGGCCTCGAGGAGGCCGACCGGGCCG
GGACCTTCCACGCCTACGTCCAGGCGGACCCCGCCCGGAAGGGGGAGGTCCTGGCCGTCCTCCAGGAGGAGCTTGACCGC
CTCGGGCGGGAGGGGGTGGGAGAGGAGGAGGTGGAACGGGCCAAGACCCCCCTCGCCACGGGCCTCGTCTTCGCCGGGGA
AACCCCCATGCAGCGGCTTTTCCACCTGGGGATGGAGTACCTCTACACCGGGCGCTACCTCTCCTTGGAGGAGGTGAAGG
CCAGGGTCCAAAGGGTCACGTCCCGGGAGGTGAACGCCCTTTTGGAGCGGGGCTTCCTGGAGAAGGGGCTTTACTACCTG
GTCCTTCCCCATGGAGCCTAG

Upstream 100 bases:

>100_bases
GAGGCCGCCATTGAGGGGACGAGCCTCGAGGCGGTGAACGCTTTCCTCAGGGCCCACCCCTACCGGGACCCCTGGGTGGG
GCTTTTGGGGGAGGTGGAGG

Downstream 100 bases:

>100_bases
GGCCTTAGGCGCGGCCCTCCTCACCCTCCTCTTCTGGGCCAGCGCCTTCGCCGCGATCCGCGCGGGGCTTGAGGGCCTAG
AGCCCGGCCACCTCGTCCTC

Product: zinc protease

Products: NA

Alternate protein names: ORFP [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MFREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDALAVNRAFDRMGAQYNAFTS
EEATVYYGAVLPEFAYDLLGLFAKLLRPALREEDFQTEKLVILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRE
SITALTREGMAAYHRRRYLPKNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLTPAFGVEERPYEKARALYLVA
LFPGVAYQEEARFPGQVLAHLLGEEGSGRLHFALVDKGLAEVASFGLEEADRAGTFHAYVQADPARKGEVLAVLQEELDR
LGREGVGEEEVERAKTPLATGLVFAGETPMQRLFHLGMEYLYTGRYLSLEEVKARVQRVTSREVNALLERGFLEKGLYYL
VLPHGA

Sequences:

>Translated_406_residues
MFREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDALAVNRAFDRMGAQYNAFTS
EEATVYYGAVLPEFAYDLLGLFAKLLRPALREEDFQTEKLVILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRE
SITALTREGMAAYHRRRYLPKNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLTPAFGVEERPYEKARALYLVA
LFPGVAYQEEARFPGQVLAHLLGEEGSGRLHFALVDKGLAEVASFGLEEADRAGTFHAYVQADPARKGEVLAVLQEELDR
LGREGVGEEEVERAKTPLATGLVFAGETPMQRLFHLGMEYLYTGRYLSLEEVKARVQRVTSREVNALLERGFLEKGLYYL
VLPHGA
>Mature_406_residues
MFREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMDALAVNRAFDRMGAQYNAFTS
EEATVYYGAVLPEFAYDLLGLFAKLLRPALREEDFQTEKLVILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRE
SITALTREGMAAYHRRRYLPKNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLTPAFGVEERPYEKARALYLVA
LFPGVAYQEEARFPGQVLAHLLGEEGSGRLHFALVDKGLAEVASFGLEEADRAGTFHAYVQADPARKGEVLAVLQEELDR
LGREGVGEEEVERAKTPLATGLVFAGETPMQRLFHLGMEYLYTGRYLSLEEVKARVQRVTSREVNALLERGFLEKGLYYL
VLPHGA

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=411, Percent_Identity=29.4403892944039, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI94538354, Length=405, Percent_Identity=28.641975308642, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI24308013, Length=374, Percent_Identity=23.7967914438503, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI155969707, Length=376, Percent_Identity=24.2021276595745, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787770, Length=402, Percent_Identity=24.1293532338308, Blast_Score=72, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71999683, Length=403, Percent_Identity=27.7915632754342, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17553678, Length=412, Percent_Identity=27.1844660194175, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32566665, Length=330, Percent_Identity=25.1515151515152, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25146566, Length=330, Percent_Identity=25.1515151515152, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71994338, Length=330, Percent_Identity=25.1515151515152, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI25146563, Length=330, Percent_Identity=25.1515151515152, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323192, Length=406, Percent_Identity=27.3399014778325, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6321813, Length=424, Percent_Identity=22.6415094339623, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323421, Length=323, Percent_Identity=25.077399380805, Blast_Score=76, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21357875, Length=394, Percent_Identity=29.1878172588832, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI24646943, Length=394, Percent_Identity=29.1878172588832, Blast_Score=135, Evalue=7e-32,
Organism=Drosophila melanogaster, GI19921772, Length=421, Percent_Identity=23.2779097387173, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 45579; Mature: 45579

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMD
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
ALAVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLLRPALREEDFQTEKL
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITALTREGMAAYHRRRYLP
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLTPAFGVEERPYEKARALYLVA
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHEEHHH
LFPGVAYQEEARFPGQVLAHLLGEEGSGRLHFALVDKGLAEVASFGLEEADRAGTFHAYV
HCCCCCCHHHCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCHHHHHCCCCEEEEE
QADPARKGEVLAVLQEELDRLGREGVGEEEVERAKTPLATGLVFAGETPMQRLFHLGMEY
ECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHCEEECCCCHHHHHHHHHHHH
LYTGRYLSLEEVKARVQRVTSREVNALLERGFLEKGLYYLVLPHGA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
>Mature Secondary Structure
MFREAELRNGLRVIAEVVPGARSVALGYFVKTGARDETKEESGVSHFLEHMVFKGPEDMD
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCHH
ALAVNRAFDRMGAQYNAFTSEEATVYYGAVLPEFAYDLLGLFAKLLRPALREEDFQTEKL
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
VILEEIARYQDRPGFMAYEWARARFFQGHPLGNSVLGTRESITALTREGMAAYHRRRYLP
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
KNMVLAATGRVDFDRLLAEAERLTEAWPEGEAERAYPPLTPAFGVEERPYEKARALYLVA
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHEEHHH
LFPGVAYQEEARFPGQVLAHLLGEEGSGRLHFALVDKGLAEVASFGLEEADRAGTFHAYV
HCCCCCCHHHCCCCHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHCHHHHHCCCCEEEEE
QADPARKGEVLAVLQEELDRLGREGVGEEEVERAKTPLATGLVFAGETPMQRLFHLGMEY
ECCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHCEEECCCCHHHHHHHHHHHH
LYTGRYLSLEEVKARVQRVTSREVNALLERGFLEKGLYYLVLPHGA
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 8098035 [H]