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The map label for this gene is minD [H]

Identifier: 55981212

GI number: 55981212

Start: 1178335

End: 1179138

Strand: Reverse

Name: minD [H]

Synonym: TTHA1243

Alternate gene names: 55981212

Gene position: 1179138-1178335 (Counterclockwise)

Preceding gene: 55981213

Following gene: 55981211

Centisome position: 63.75

GC content: 69.65

Gene sequence:

>804_bases
GTGAAGGCGCGAGCCATCGTGGTGACTTCCGGCAAGGGCGGGGTGGGGAAGACCACCACCACCGCCAACCTCGGCGCCGC
CTTGGCCAAGCTCGGGGAAAAGGTGGCCGTGGTGGACGTGGACGTGGGCCTCCGCAACCTGGACGTGGTCATGGGCCTCG
AGGGCCGGGTGGTCTTTGACCTGGTGGACGTCCTCGAGGGCCGGGCCAGGCTCCGGCAGGCCCTCATCCGGGACAAGCGG
GTGGAGAACCTCTTCCTCCTTCCCGCCTCCCAGACGAAGGACAAGGAGGCCCTGGACCCCGAGCGCTTCAAGGAGGTGGT
GCGGGCCCTCTTGGAGGAGGAGGGCTTTGACCGGGTGCTCATAGACTCCCCCGCCGGCATAGAGAAGGGCTTCCAGACGG
CGGCCGCTCCGGCGGAGGGGGCCTTGGTGGTGGTGAACCCCGAGGTCAGTAGCGTCCGCGACGCCGACCGGATCATCGGC
CTCCTGGAGGCCCGGGAGGTGCGGGAGAACTTCCTCGTCATCAACCGCCTGCGCCCCAGGATGGTGGCCCGGGGGGACAT
GCTCTCCGTGGAGGACGTGGTGGAGATCCTGGGCCTGAAGCCCATCGGCATCATCCCCGAGGACGAGCAGGTGATCGTCT
CCACCAACCAGGGGGAGCCCTTGGTCCTGAAGGGGACGGGCCCCGCCGCCCAGGCCTACATGGACACGGCGCGGCGCCTC
CGGGGCGAGGAGGTGCCCTTCCGCGCCCTCGAGGACGCCCAGGGCCTTCTCGGGGTGCTGAAGCGCCTCTTTGGGGGTCG
GTGA

Upstream 100 bases:

>100_bases
TGCCGCCTCGGGTAGAATATAGCCTCACGCCTAGGGGCAAGCGGGTCTTGGAGTTTCTGATGGAGCTGGACCGCGTGGTG
GAAACCCTGGAGGAGGTACG

Downstream 100 bases:

>100_bases
TGTGGTGGCGCAGGAGGAGCAAGGAGAAGGCCAAGGAAAGGCTCAAGCTCGTGCTGGCCTACGACCGGGCGCGGCTTTCC
CCGGGGATGGTGGAAAGCCT

Product: septum site-determining protein MinD

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MKARAIVVTSGKGGVGKTTTTANLGAALAKLGEKVAVVDVDVGLRNLDVVMGLEGRVVFDLVDVLEGRARLRQALIRDKR
VENLFLLPASQTKDKEALDPERFKEVVRALLEEEGFDRVLIDSPAGIEKGFQTAAAPAEGALVVVNPEVSSVRDADRIIG
LLEAREVRENFLVINRLRPRMVARGDMLSVEDVVEILGLKPIGIIPEDEQVIVSTNQGEPLVLKGTGPAAQAYMDTARRL
RGEEVPFRALEDAQGLLGVLKRLFGGR

Sequences:

>Translated_267_residues
MKARAIVVTSGKGGVGKTTTTANLGAALAKLGEKVAVVDVDVGLRNLDVVMGLEGRVVFDLVDVLEGRARLRQALIRDKR
VENLFLLPASQTKDKEALDPERFKEVVRALLEEEGFDRVLIDSPAGIEKGFQTAAAPAEGALVVVNPEVSSVRDADRIIG
LLEAREVRENFLVINRLRPRMVARGDMLSVEDVVEILGLKPIGIIPEDEQVIVSTNQGEPLVLKGTGPAAQAYMDTARRL
RGEEVPFRALEDAQGLLGVLKRLFGGR
>Mature_267_residues
MKARAIVVTSGKGGVGKTTTTANLGAALAKLGEKVAVVDVDVGLRNLDVVMGLEGRVVFDLVDVLEGRARLRQALIRDKR
VENLFLLPASQTKDKEALDPERFKEVVRALLEEEGFDRVLIDSPAGIEKGFQTAAAPAEGALVVVNPEVSSVRDADRIIG
LLEAREVRENFLVINRLRPRMVARGDMLSVEDVVEILGLKPIGIIPEDEQVIVSTNQGEPLVLKGTGPAAQAYMDTARRL
RGEEVPFRALEDAQGLLGVLKRLFGGR

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=272, Percent_Identity=53.3088235294118, Blast_Score=268, Evalue=3e-73,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 28891; Mature: 28891

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKARAIVVTSGKGGVGKTTTTANLGAALAKLGEKVAVVDVDVGLRNLDVVMGLEGRVVFD
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCEEEEECCCCCHHHH
LVDVLEGRARLRQALIRDKRVENLFLLPASQTKDKEALDPERFKEVVRALLEEEGFDRVL
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
IDSPAGIEKGFQTAAAPAEGALVVVNPEVSSVRDADRIIGLLEAREVRENFLVINRLRPR
ECCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCH
MVARGDMLSVEDVVEILGLKPIGIIPEDEQVIVSTNQGEPLVLKGTGPAAQAYMDTARRL
HHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
RGEEVPFRALEDAQGLLGVLKRLFGGR
CCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKARAIVVTSGKGGVGKTTTTANLGAALAKLGEKVAVVDVDVGLRNLDVVMGLEGRVVFD
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCCEEEEECCCCCHHHH
LVDVLEGRARLRQALIRDKRVENLFLLPASQTKDKEALDPERFKEVVRALLEEEGFDRVL
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
IDSPAGIEKGFQTAAAPAEGALVVVNPEVSSVRDADRIIGLLEAREVRENFLVINRLRPR
ECCCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEHHCCCCH
MVARGDMLSVEDVVEILGLKPIGIIPEDEQVIVSTNQGEPLVLKGTGPAAQAYMDTARRL
HHHCCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEECCCCHHHHHHHHHHHH
RGEEVPFRALEDAQGLLGVLKRLFGGR
CCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1400225; 8459776; 1400224; 9384377 [H]