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The map label for this gene is pld [H]

Identifier: 55981156

GI number: 55981156

Start: 1133761

End: 1134891

Strand: Direct

Name: pld [H]

Synonym: TTHA1187

Alternate gene names: 55981156

Gene position: 1133761-1134891 (Clockwise)

Preceding gene: 55981155

Following gene: 55981157

Centisome position: 61.29

GC content: 68.26

Gene sequence:

>1131_bases
TTGGCTACTAGGAGGCGCCGGGGCAGGAAGGCGATCGCCGGGCTTCCCGGCTACCTCCTCCTCCTGGTCCTCGTCCTGGT
CTGGCTCTTCCAAGAGCTCCGGCCGGGCCCCGCCCCGCCCGCCGAGACGGGAGAGGCCGAGGTCTACTTCATGCCGGAGG
AAGGGCCGAGGGCCAAGGCTCGCCTCCTCGCCCTCATGGACGGGGCCCGGGAAAGCCTGGAAGGAGCCTTCTACGAGTTC
CGCGACCTGGAGGTCGCCCAGGGCCTCCTCCGGGCCAAGGCGCGGGGGGTGAGGGTGCGGCTTTACGGGGAAAGCGACTA
CCGGGAGGACTTCCGCCGCTATTTGGTGGCGGCGAGCCTGGGCCAGAGGGAGGAGCCCCCGAGGGTCCGCTTCGCCGAGC
TCAAGGAGCGGGTCAGGCCCCTCTCCCTGGACTGCGAGGAGGTCGCGGGGATCCCCATCTGCTACGACGAGCGGGAAGGC
TTCATGCACCACAAGTTCCTGGTGGTGGACGGGAGGGCCGTCTGGACGGGGAGCACCAACATGACCTGGAACGCCTTCGC
CCGGAACAACGAGAACAGCCTCCTCCTCCCCTCCCCCACCCTGGCCCAGGGGTACGCGCGGGAGTTTGAGGCCCTCTTCG
GCGGACAGAAGGAAGGCCTCGGCCAGCCCGTGGCCTTCGCCCTGGAGGCGGTGGAGGGCGTGGCCTACTTCAGCCCAAGG
GGAGGGAGGCTCGCCCGGGAAGCCCTCCTGAAGCGGCTTTCCGAGGCCCAAAGGGAGGTCTTGGTGGCGGCCTTCGTCCT
CACGGACCGGGAACTGGTGGAAGCCCTTAAGGAAGCCCACGGCCGGGGTCTTTCCGTCCGGATCCTTTTGGAAAGGCGCA
ACCTGGGGGACAGCCGGGAGGAGGACCTCCTTAGGGCGGGCGTCCCCGTGCGCCAGGACGCCAACCCCTACACCATGCAC
CACAAGGTCATGGTCCTGGACGGCACCTACGTGGTCACCGGGAGCTACAACTTCTCCGTCCGGGCCCACGAGGTGAACAA
CGAGAACCTCCTCGTGCTCAAAAGCCCGAGCCTGGCGGAGCGCTACCGGAAGGAGGTGTTGCGGCTTTGGGAAGCGGGAA
GCCCCCTCTGA

Upstream 100 bases:

>100_bases
ATCCGGGACCGGGAGACCGCCCTGAGGATGCTGAAGGCCGGGGCGAGCCGCCTCGGGACCTCCAGCGGCGTGGCCCTGGT
GGCGGGGGAAGGGGGGACCC

Downstream 100 bases:

>100_bases
TCCTGGCCTCGGGAAGCCCCAGGCGGAAAGCCCTCCTCGAGGCCCTGGGCTACCCCATCCGGGTTGCGGTCCCCGGGGTG
GAGGAAGAGGGCCTCCCCCT

Product: hypothetical protein

Products: NA

Alternate protein names: PLD; Choline phosphatase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MATRRRRGRKAIAGLPGYLLLLVLVLVWLFQELRPGPAPPAETGEAEVYFMPEEGPRAKARLLALMDGARESLEGAFYEF
RDLEVAQGLLRAKARGVRVRLYGESDYREDFRRYLVAASLGQREEPPRVRFAELKERVRPLSLDCEEVAGIPICYDEREG
FMHHKFLVVDGRAVWTGSTNMTWNAFARNNENSLLLPSPTLAQGYAREFEALFGGQKEGLGQPVAFALEAVEGVAYFSPR
GGRLAREALLKRLSEAQREVLVAAFVLTDRELVEALKEAHGRGLSVRILLERRNLGDSREEDLLRAGVPVRQDANPYTMH
HKVMVLDGTYVVTGSYNFSVRAHEVNNENLLVLKSPSLAERYRKEVLRLWEAGSPL

Sequences:

>Translated_376_residues
MATRRRRGRKAIAGLPGYLLLLVLVLVWLFQELRPGPAPPAETGEAEVYFMPEEGPRAKARLLALMDGARESLEGAFYEF
RDLEVAQGLLRAKARGVRVRLYGESDYREDFRRYLVAASLGQREEPPRVRFAELKERVRPLSLDCEEVAGIPICYDEREG
FMHHKFLVVDGRAVWTGSTNMTWNAFARNNENSLLLPSPTLAQGYAREFEALFGGQKEGLGQPVAFALEAVEGVAYFSPR
GGRLAREALLKRLSEAQREVLVAAFVLTDRELVEALKEAHGRGLSVRILLERRNLGDSREEDLLRAGVPVRQDANPYTMH
HKVMVLDGTYVVTGSYNFSVRAHEVNNENLLVLKSPSLAERYRKEVLRLWEAGSPL
>Mature_375_residues
ATRRRRGRKAIAGLPGYLLLLVLVLVWLFQELRPGPAPPAETGEAEVYFMPEEGPRAKARLLALMDGARESLEGAFYEFR
DLEVAQGLLRAKARGVRVRLYGESDYREDFRRYLVAASLGQREEPPRVRFAELKERVRPLSLDCEEVAGIPICYDEREGF
MHHKFLVVDGRAVWTGSTNMTWNAFARNNENSLLLPSPTLAQGYAREFEALFGGQKEGLGQPVAFALEAVEGVAYFSPRG
GRLAREALLKRLSEAQREVLVAAFVLTDRELVEALKEAHGRGLSVRILLERRNLGDSREEDLLRAGVPVRQDANPYTMHH
KVMVLDGTYVVTGSYNFSVRAHEVNNENLLVLKSPSLAERYRKEVLRLWEAGSPL

Specific function: Could be a virulence factor [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PLD phosphodiesterase domain [H]

Homologues:

Organism=Homo sapiens, GI270265812, Length=116, Percent_Identity=31.0344827586207, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: NA

EC number: =3.1.4.4 [H]

Molecular weight: Translated: 42362; Mature: 42231

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATRRRRGRKAIAGLPGYLLLLVLVLVWLFQELRPGPAPPAETGEAEVYFMPEEGPRAKA
CCCCHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHH
RLLALMDGARESLEGAFYEFRDLEVAQGLLRAKARGVRVRLYGESDYREDFRRYLVAASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHC
GQREEPPRVRFAELKERVRPLSLDCEEVAGIPICYDEREGFMHHKFLVVDGRAVWTGSTN
CCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCEEEEEEEEECEEEEECCCC
MTWNAFARNNENSLLLPSPTLAQGYAREFEALFGGQKEGLGQPVAFALEAVEGVAYFSPR
CEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCC
GGRLAREALLKRLSEAQREVLVAAFVLTDRELVEALKEAHGRGLSVRILLERRNLGDSRE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHH
EDLLRAGVPVRQDANPYTMHHKVMVLDGTYVVTGSYNFSVRAHEVNNENLLVLKSPSLAE
HHHHHCCCCCCCCCCCEEEEEEEEEEECEEEEEECEEEEEEEEEECCCCEEEEECCHHHH
RYRKEVLRLWEAGSPL
HHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATRRRRGRKAIAGLPGYLLLLVLVLVWLFQELRPGPAPPAETGEAEVYFMPEEGPRAKA
CCCHHCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHH
RLLALMDGARESLEGAFYEFRDLEVAQGLLRAKARGVRVRLYGESDYREDFRRYLVAASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHC
GQREEPPRVRFAELKERVRPLSLDCEEVAGIPICYDEREGFMHHKFLVVDGRAVWTGSTN
CCCCCCCCCHHHHHHHHCCCCCCCHHHHCCCCEEECCCCCCEEEEEEEEECEEEEECCCC
MTWNAFARNNENSLLLPSPTLAQGYAREFEALFGGQKEGLGQPVAFALEAVEGVAYFSPR
CEEEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEECCC
GGRLAREALLKRLSEAQREVLVAAFVLTDRELVEALKEAHGRGLSVRILLERRNLGDSRE
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCHH
EDLLRAGVPVRQDANPYTMHHKVMVLDGTYVVTGSYNFSVRAHEVNNENLLVLKSPSLAE
HHHHHCCCCCCCCCCCEEEEEEEEEEECEEEEEECEEEEEEEEEECCCCEEEEECCHHHH
RYRKEVLRLWEAGSPL
HHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]