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The map label for this gene is pbpG [H]

Identifier: 55981152

GI number: 55981152

Start: 1128875

End: 1130962

Strand: Reverse

Name: pbpG [H]

Synonym: TTHA1183

Alternate gene names: 55981152

Gene position: 1130962-1128875 (Counterclockwise)

Preceding gene: 55981153

Following gene: 55981151

Centisome position: 61.14

GC content: 71.84

Gene sequence:

>2088_bases
GTGGCCGTGCGGCTTGCGCGGTTACTCCTCTGGGGCCTTTGGGGGGCGGTTTTGGGCGGGGCGGGGGCGTTGGGGTATTT
GGTCTACGCCTACACCCGGGACCTGCCCGACCTCTCCGCCTTTGAGAGGCTCCGGCTCACCGCCACCACCACCCTCTACG
CCCGGGACGGCTCCACCCTCGCCCTCCTCGCCAGCGTGGAGGACGGGCGGGCCATCAACCGGAGCCTGGTCCGCCTCTCT
GAGGTCTCGCCCGCGGCCCTCGCCGCCATCGTCTTCTCCGAGGACCGGCGCTTCTACAGCCACTACGGCGTGGATCCCGT
GCGCCTTCTCGGGGCCCTGTACGCGGTGCTCACCGGGGACCTCCAGGGGGGGAGCACCGTCACCACCCAGGTCATCAAGA
ACACCCTCCTCAAGGAGCTCGCCCAGGCCCGCACCCTGGAGCGCAAGGTGAAGGAGTGGGTCCTGGCCCTGGAGCTGGAG
AGGCGCTACACCAAGGCGGAGATCCTGGAGATGTACCTCAACGTGGTCCCCTGGGGGGGGAACGCCGTGGGCATCCGGGC
CGCCGCCGAGGCCTACTTCGGCAAGGACCCCGCGGCCTTGACCCTCGCCGAGGGGCTCTATTTGGCGAGCCTCATCCCCG
CGCCCAACGCCCGCTACCAGGACCTCGAGGGGGTGCGCCGCCGCATGCGCCGGGTCCTGGACGAGATGGTCCGGGAGGGC
TGGATTACGGAGGCCCTGGCGGAGCGGGCCTGGAAGGAGCCGCTTAAGCCCAGGGGCTGGGAGGTGCGCTACGACGAGGA
GGGCAACCTTCTGGAGGCCCGCCTGGTGGACCCGGAGGCCCGCATCCTCCGCTCCGTGGACTACCGCCTCGCCCCCCACT
TCGTCCTCGAGGTGCGGCGCTTCCTGGAGGAGCGCTTCGGCAAGGAGAAGGTCTACGGGGAGGGGGGGCTTAAGGTCTAC
ACCACCCTGGACCCGAGGATGCAGGAGGCCGCGGAGAAGGCGGCCCGGGCGGCCCGGCTTCCCGAGGGGGCGGACCTCGC
CATCGTGGGCCTGGACCCGGAGACGGGGGAGGTCTTGGCCATGGTGGGCGGGGTGCGCCGGGAGAACGACGAGTACAACC
GGGCGACCCGGGCCCTGAGAAACCCGGGGAGCGCGGTCAAGCCCTTCGTCTACGCCGCCGCCCTGGAGGCGGGCTGGACC
CAGGTGACCCTGGTGCCCGACCGGCCCATGGAGTTCAAGGACCCGAGCCAGCCTGGGGGCGTCTGGCGGCCCAAGAACTT
CTCCGGCACCTTCCTGAACCGGGAGATCACGGTGCGCTACGCCCTGGACCTTTCCCTCAACCTCCCCGCCGTCTACACCG
CCCAGGCGGTGGGCCTGGACCGGGTGGCGGCGAAGCTCGCCCAGGCGGGGTTCGCGGTGCGCTACGCCGTCCCCGCCATC
GCCATCGGGGGGGCCTCCATTACCCCTGTGGACCTGGCCGCGGCCTACGCTGCCTTCGTCAACGGCGGCTACCGGGTGGC
CCCCCTCCTGGTCCTGCGGGTGGAGGACCAGGAGGGCCGGGTCCTGTACCAGGCCACCCCCCACAGGACGCGGCTCTTCA
GCCCGGAGGTGGCCTACCAGGGTTGGGACCTCCTCAAGGGGTACGTCTACGACCTGGGGGAGAAGGGCCTCGCCAAGGGG
GCCAGGATCCCGGGGCGGGTGGTGGGGGGGAAGACGGGCACCACCAACGAGGCCCGGGACCTCTGGTTCGCCGGGGTGAC
CCGGGGGCTTTCCGCCGTGGTCTGGGTGGGGCGGGACGACAACCGGCCCCTCAGGATGGGGGGGAGGGAGCCCAGTAGCT
CCGTGGTCAACCCCCCCATCTGGCGGGACTTCGTGGCCGAGGCCCTAAAGGGGCGCCCTGGGGGCGACTTCCCTCCCCCT
TCGGGGCTTGTGCCCGTGCGGGTGGACCTGGAGACCGGCCTGCCGAGCGAGAAGGGGGTGGTGGTCTACGTGCCCGAGGG
CAAGGTGCCCTCGGGGAGGCCCCCGGAGGAAAGCCCCGCCTTGCCCCTTCCCCTCCCCCTCCTCACGCCCCCGGGGGGCG
GGCTTTAG

Upstream 100 bases:

>100_bases
ACCACGGCGGAGGTCGTCCGGGTCCAGGCCATGGAGAAGCCCCTGACCCGCGAGAAGCTCTACCGCTTTTTGGGCCTGGC
GTAGGGGTTTGGGTAAACTG

Downstream 100 bases:

>100_bases
GAGGTCTTGCGTGGAGCGGGTGAGGATCGTCCTGGTGGAGCCCCAGGAGCCGATGAACCTGGGGGCGGTGGCCCGGGCCA
TGCGGAACTTCGGGCTTTCC

Product: penicillin-binding protein 1B

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 695; Mature: 694

Protein sequence:

>695_residues
MAVRLARLLLWGLWGAVLGGAGALGYLVYAYTRDLPDLSAFERLRLTATTTLYARDGSTLALLASVEDGRAINRSLVRLS
EVSPAALAAIVFSEDRRFYSHYGVDPVRLLGALYAVLTGDLQGGSTVTTQVIKNTLLKELAQARTLERKVKEWVLALELE
RRYTKAEILEMYLNVVPWGGNAVGIRAAAEAYFGKDPAALTLAEGLYLASLIPAPNARYQDLEGVRRRMRRVLDEMVREG
WITEALAERAWKEPLKPRGWEVRYDEEGNLLEARLVDPEARILRSVDYRLAPHFVLEVRRFLEERFGKEKVYGEGGLKVY
TTLDPRMQEAAEKAARAARLPEGADLAIVGLDPETGEVLAMVGGVRRENDEYNRATRALRNPGSAVKPFVYAAALEAGWT
QVTLVPDRPMEFKDPSQPGGVWRPKNFSGTFLNREITVRYALDLSLNLPAVYTAQAVGLDRVAAKLAQAGFAVRYAVPAI
AIGGASITPVDLAAAYAAFVNGGYRVAPLLVLRVEDQEGRVLYQATPHRTRLFSPEVAYQGWDLLKGYVYDLGEKGLAKG
ARIPGRVVGGKTGTTNEARDLWFAGVTRGLSAVVWVGRDDNRPLRMGGREPSSSVVNPPIWRDFVAEALKGRPGGDFPPP
SGLVPVRVDLETGLPSEKGVVVYVPEGKVPSGRPPEESPALPLPLPLLTPPGGGL

Sequences:

>Translated_695_residues
MAVRLARLLLWGLWGAVLGGAGALGYLVYAYTRDLPDLSAFERLRLTATTTLYARDGSTLALLASVEDGRAINRSLVRLS
EVSPAALAAIVFSEDRRFYSHYGVDPVRLLGALYAVLTGDLQGGSTVTTQVIKNTLLKELAQARTLERKVKEWVLALELE
RRYTKAEILEMYLNVVPWGGNAVGIRAAAEAYFGKDPAALTLAEGLYLASLIPAPNARYQDLEGVRRRMRRVLDEMVREG
WITEALAERAWKEPLKPRGWEVRYDEEGNLLEARLVDPEARILRSVDYRLAPHFVLEVRRFLEERFGKEKVYGEGGLKVY
TTLDPRMQEAAEKAARAARLPEGADLAIVGLDPETGEVLAMVGGVRRENDEYNRATRALRNPGSAVKPFVYAAALEAGWT
QVTLVPDRPMEFKDPSQPGGVWRPKNFSGTFLNREITVRYALDLSLNLPAVYTAQAVGLDRVAAKLAQAGFAVRYAVPAI
AIGGASITPVDLAAAYAAFVNGGYRVAPLLVLRVEDQEGRVLYQATPHRTRLFSPEVAYQGWDLLKGYVYDLGEKGLAKG
ARIPGRVVGGKTGTTNEARDLWFAGVTRGLSAVVWVGRDDNRPLRMGGREPSSSVVNPPIWRDFVAEALKGRPGGDFPPP
SGLVPVRVDLETGLPSEKGVVVYVPEGKVPSGRPPEESPALPLPLPLLTPPGGGL
>Mature_694_residues
AVRLARLLLWGLWGAVLGGAGALGYLVYAYTRDLPDLSAFERLRLTATTTLYARDGSTLALLASVEDGRAINRSLVRLSE
VSPAALAAIVFSEDRRFYSHYGVDPVRLLGALYAVLTGDLQGGSTVTTQVIKNTLLKELAQARTLERKVKEWVLALELER
RYTKAEILEMYLNVVPWGGNAVGIRAAAEAYFGKDPAALTLAEGLYLASLIPAPNARYQDLEGVRRRMRRVLDEMVREGW
ITEALAERAWKEPLKPRGWEVRYDEEGNLLEARLVDPEARILRSVDYRLAPHFVLEVRRFLEERFGKEKVYGEGGLKVYT
TLDPRMQEAAEKAARAARLPEGADLAIVGLDPETGEVLAMVGGVRRENDEYNRATRALRNPGSAVKPFVYAAALEAGWTQ
VTLVPDRPMEFKDPSQPGGVWRPKNFSGTFLNREITVRYALDLSLNLPAVYTAQAVGLDRVAAKLAQAGFAVRYAVPAIA
IGGASITPVDLAAAYAAFVNGGYRVAPLLVLRVEDQEGRVLYQATPHRTRLFSPEVAYQGWDLLKGYVYDLGEKGLAKGA
RIPGRVVGGKTGTTNEARDLWFAGVTRGLSAVVWVGRDDNRPLRMGGREPSSSVVNPPIWRDFVAEALKGRPGGDFPPPS
GLVPVRVDLETGLPSEKGVVVYVPEGKVPSGRPPEESPALPLPLPLLTPPGGGL

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=626, Percent_Identity=30.3514376996805, Blast_Score=203, Evalue=3e-53,
Organism=Escherichia coli, GI1788867, Length=568, Percent_Identity=32.5704225352113, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI87082258, Length=327, Percent_Identity=35.474006116208, Blast_Score=145, Evalue=7e-36,
Organism=Escherichia coli, GI1789601, Length=168, Percent_Identity=32.1428571428571, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 75910; Mature: 75779

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVRLARLLLWGLWGAVLGGAGALGYLVYAYTRDLPDLSAFERLRLTATTTLYARDGSTL
CHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHEEEEEEEEEEEECCCEE
ALLASVEDGRAINRSLVRLSEVSPAALAAIVFSEDRRFYSHYGVDPVRLLGALYAVLTGD
EEEEECCCCHHHHHHHHHHHCCCHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHCC
LQGGSTVTTQVIKNTLLKELAQARTLERKVKEWVLALELERRYTKAEILEMYLNVVPWGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NAVGIRAAAEAYFGKDPAALTLAEGLYLASLIPAPNARYQDLEGVRRRMRRVLDEMVREG
CEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
WITEALAERAWKEPLKPRGWEVRYDEEGNLLEARLVDPEARILRSVDYRLAPHFVLEVRR
HHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHCHHHHHHHHH
FLEERFGKEKVYGEGGLKVYTTLDPRMQEAAEKAARAARLPEGADLAIVGLDPETGEVLA
HHHHHCCCCEEECCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
MVGGVRRENDEYNRATRALRNPGSAVKPFVYAAALEAGWTQVTLVPDRPMEFKDPSQPGG
HHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
VWRPKNFSGTFLNREITVRYALDLSLNLPAVYTAQAVGLDRVAAKLAQAGFAVRYAVPAI
CCCCCCCCCCEECCEEEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCEE
AIGGASITPVDLAAAYAAFVNGGYRVAPLLVLRVEDQEGRVLYQATPHRTRLFSPEVAYQ
EECCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCEEEEECCCCCEECCCHHHHC
GWDLLKGYVYDLGEKGLAKGARIPGRVVGGKTGTTNEARDLWFAGVTRGLSAVVWVGRDD
CHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCC
NRPLRMGGREPSSSVVNPPIWRDFVAEALKGRPGGDFPPPSGLVPVRVDLETGLPSEKGV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCE
VVYVPEGKVPSGRPPEESPALPLPLPLLTPPGGGL
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AVRLARLLLWGLWGAVLGGAGALGYLVYAYTRDLPDLSAFERLRLTATTTLYARDGSTL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHEEEEEEEEEEEECCCEE
ALLASVEDGRAINRSLVRLSEVSPAALAAIVFSEDRRFYSHYGVDPVRLLGALYAVLTGD
EEEEECCCCHHHHHHHHHHHCCCHHHHEEEEECCCCHHHHHCCCCHHHHHHHHHHHHHCC
LQGGSTVTTQVIKNTLLKELAQARTLERKVKEWVLALELERRYTKAEILEMYLNVVPWGG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NAVGIRAAAEAYFGKDPAALTLAEGLYLASLIPAPNARYQDLEGVRRRMRRVLDEMVREG
CEEEHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
WITEALAERAWKEPLKPRGWEVRYDEEGNLLEARLVDPEARILRSVDYRLAPHFVLEVRR
HHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHCHHHHHHHHH
FLEERFGKEKVYGEGGLKVYTTLDPRMQEAAEKAARAARLPEGADLAIVGLDPETGEVLA
HHHHHCCCCEEECCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHH
MVGGVRRENDEYNRATRALRNPGSAVKPFVYAAALEAGWTQVTLVPDRPMEFKDPSQPGG
HHCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCC
VWRPKNFSGTFLNREITVRYALDLSLNLPAVYTAQAVGLDRVAAKLAQAGFAVRYAVPAI
CCCCCCCCCCEECCEEEEEEEEEEEECCCCEEHHHHHHHHHHHHHHHHCCCEEEEECCEE
AIGGASITPVDLAAAYAAFVNGGYRVAPLLVLRVEDQEGRVLYQATPHRTRLFSPEVAYQ
EECCCCCCHHHHHHHHHHHHCCCEEEEEEEEEEEECCCCCEEEEECCCCCEECCCHHHHC
GWDLLKGYVYDLGEKGLAKGARIPGRVVGGKTGTTNEARDLWFAGVTRGLSAVVWVGRDD
CHHHHHHHHHHCCCHHHHCCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCEEEEEEECCC
NRPLRMGGREPSSSVVNPPIWRDFVAEALKGRPGGDFPPPSGLVPVRVDLETGLPSEKGV
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCCE
VVYVPEGKVPSGRPPEESPALPLPLPLLTPPGGGL
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]