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The map label for this gene is trkG [H]

Identifier: 55981142

GI number: 55981142

Start: 1118715

End: 1120187

Strand: Reverse

Name: trkG [H]

Synonym: TTHA1173

Alternate gene names: 55981142

Gene position: 1120187-1118715 (Counterclockwise)

Preceding gene: 55981143

Following gene: 55981141

Centisome position: 60.56

GC content: 69.86

Gene sequence:

>1473_bases
ATGAGGTCCTGGCTCCCTTCTTCCCGGAGTAAGGGGGCCCTGGAGGCCCTCCTCTACCTCCTCGGCCTCACCTTCCGGGG
CTTCGCCTTCGTCCACCTGGGCTTCGCCGCCTTGGCCCTGGTCCTGGGGGAGGAGGCCTGGGGCTTCCTGGGGGCGGCGG
CCTTGGGGTTTGCCCTGGGGTACCTCGGTACCTTCCGGGGCAGGCCCAAGGCCCAGCCCCAGCGGGCCGAGGTCTTCGCC
GGGGTGGCCCTCCTTTGGCTTCTTGTCCCGGTGCTCGGGGCGGTGCCCTACTGGATCTCGGGGGGGCTTGCCTTCCTGGA
CGCCCTCTTTGAGTCCATGTCGGGGTACACCGCCACCGGGGCCACGGTTCTGCAGGACTTCTCCTTAAGCCGAAGCCTCT
TCCTCTACCGGGGCTTCACCCAGTGGATGGGGGGGATCGGGATCGTGGTGCTTTTCCTCGCGGTCTTCCCCCAGCTCCAC
GTGGCGGGGCGCCAGGCCTTCTTCGCCGAGAGCACCGGGGTGGAGAAGGAGCGCCTCACCCCGAGGATCCGCCAGACGGC
CCAGGCGGTCCTCCTCCTCTACCTGGCCCTCACCGGGGCCGCCGCCTTGGGGTACGCCCTCGCCGGGGTGCCCCTCTTTG
AGGCGGTGGCCAACGCCTTGGCCACGGTCCCCGCCGGGGGGTTCAGCCCCAACCCCCAGAGCTTCGCCGGTTACCCGCCC
CTCGCCCAGTGGCTCGGGGTGGCCTTCATGTTCCTCGCCGGGGTGAACTTCCTCCTGCAGTACCGCCTCTTCTTCCGGGG
CGAGGTGGGGCCCCTTCTTCGGGACGCCGAGTTTCGCGCCTACGTCCTCGTGGTCCTGGCCGCGGGCCTCGCGCTTTCCG
GCTACCTCTACACCCACCACACCTACGACCTCGAGGCCAGCCTCCGCCACGCCTTCTTCCAGGTGATCTCCATCCTCACC
GGCACGGGCTTCGCCAGCGTGGACTTCGCGCAGTGGGTGGTCCCGGCCCAGGCCATCCTGGTCCTCCTCATGTTCGTGGG
GGGAAGCGCGGGCTCGGCGGCGGGGGGGATCAAGTTGGTGCGCTGGCTCGTCCTCTTCGGCTTCCTCCGCCGGGAGATCA
CCCGCACCCTCCACCCCCAGGCGGTCCTCCCCTTGCGCCTGGGGGGGCGGGTGCTCTCGGAGGAGGTCCTGCGGCAGGTC
TCCGTCTTCATCCTCCTCTACACCCTCCTCTTCGTCCTGGGGGCCGTGGCCCTGGCCTTTTTGGAAAAGGACTTTGTCGT
GGCCTTCACCGCCAGCGCCCAGGCCATCGGCAACATCGGCCCCGGCCTCGGCGAGGTGGGGCCCATGGGCTCCTACGCGG
GGCTTCACCCCCTCTCCAAGCTCCTCCTCGTGGGGCTCATGTGGGCGGGGCGGATTGAGGTGGTGCCCGTGGTCCTCCTC
CTGACCCCGGAGCTTTGGCGCAGGCTCCGCTGA

Upstream 100 bases:

>100_bases
GTGGCCCTGGAGCGGGACCACCGGATCTTCCTCTACGAGGAGGGGCTGGGGCTTCTCCCCGGGGACAGGCTCTACCTGGT
GGCGGCCCGCGAGGTGGCCG

Downstream 100 bases:

>100_bases
GTATAATCCGGAGCATGAACGTTCTCGGACGGATCACCGCCATGCCCGACCTCCCCGAGCCCCTGGAGGGGCTTAAGGAG
ATCGCCTACAACCTCTGGTG

Product: Trk system potassium uptake protein TrkG

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MRSWLPSSRSKGALEALLYLLGLTFRGFAFVHLGFAALALVLGEEAWGFLGAAALGFALGYLGTFRGRPKAQPQRAEVFA
GVALLWLLVPVLGAVPYWISGGLAFLDALFESMSGYTATGATVLQDFSLSRSLFLYRGFTQWMGGIGIVVLFLAVFPQLH
VAGRQAFFAESTGVEKERLTPRIRQTAQAVLLLYLALTGAAALGYALAGVPLFEAVANALATVPAGGFSPNPQSFAGYPP
LAQWLGVAFMFLAGVNFLLQYRLFFRGEVGPLLRDAEFRAYVLVVLAAGLALSGYLYTHHTYDLEASLRHAFFQVISILT
GTGFASVDFAQWVVPAQAILVLLMFVGGSAGSAAGGIKLVRWLVLFGFLRREITRTLHPQAVLPLRLGGRVLSEEVLRQV
SVFILLYTLLFVLGAVALAFLEKDFVVAFTASAQAIGNIGPGLGEVGPMGSYAGLHPLSKLLLVGLMWAGRIEVVPVVLL
LTPELWRRLR

Sequences:

>Translated_490_residues
MRSWLPSSRSKGALEALLYLLGLTFRGFAFVHLGFAALALVLGEEAWGFLGAAALGFALGYLGTFRGRPKAQPQRAEVFA
GVALLWLLVPVLGAVPYWISGGLAFLDALFESMSGYTATGATVLQDFSLSRSLFLYRGFTQWMGGIGIVVLFLAVFPQLH
VAGRQAFFAESTGVEKERLTPRIRQTAQAVLLLYLALTGAAALGYALAGVPLFEAVANALATVPAGGFSPNPQSFAGYPP
LAQWLGVAFMFLAGVNFLLQYRLFFRGEVGPLLRDAEFRAYVLVVLAAGLALSGYLYTHHTYDLEASLRHAFFQVISILT
GTGFASVDFAQWVVPAQAILVLLMFVGGSAGSAAGGIKLVRWLVLFGFLRREITRTLHPQAVLPLRLGGRVLSEEVLRQV
SVFILLYTLLFVLGAVALAFLEKDFVVAFTASAQAIGNIGPGLGEVGPMGSYAGLHPLSKLLLVGLMWAGRIEVVPVVLL
LTPELWRRLR
>Mature_490_residues
MRSWLPSSRSKGALEALLYLLGLTFRGFAFVHLGFAALALVLGEEAWGFLGAAALGFALGYLGTFRGRPKAQPQRAEVFA
GVALLWLLVPVLGAVPYWISGGLAFLDALFESMSGYTATGATVLQDFSLSRSLFLYRGFTQWMGGIGIVVLFLAVFPQLH
VAGRQAFFAESTGVEKERLTPRIRQTAQAVLLLYLALTGAAALGYALAGVPLFEAVANALATVPAGGFSPNPQSFAGYPP
LAQWLGVAFMFLAGVNFLLQYRLFFRGEVGPLLRDAEFRAYVLVVLAAGLALSGYLYTHHTYDLEASLRHAFFQVISILT
GTGFASVDFAQWVVPAQAILVLLMFVGGSAGSAAGGIKLVRWLVLFGFLRREITRTLHPQAVLPLRLGGRVLSEEVLRQV
SVFILLYTLLFVLGAVALAFLEKDFVVAFTASAQAIGNIGPGLGEVGPMGSYAGLHPLSKLLLVGLMWAGRIEVVPVVLL
LTPELWRRLR

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=429, Percent_Identity=36.3636363636364, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI48994987, Length=427, Percent_Identity=35.1288056206089, Blast_Score=210, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52716; Mature: 52716

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHCC
>Mature Secondary Structure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CCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]