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The map label for this gene is 55981118

Identifier: 55981118

GI number: 55981118

Start: 1094657

End: 1095316

Strand: Direct

Name: 55981118

Synonym: TTHA1149

Alternate gene names: NA

Gene position: 1094657-1095316 (Clockwise)

Preceding gene: 55981117

Following gene: 55981121

Centisome position: 59.18

GC content: 71.67

Gene sequence:

>660_bases
ATGGACAGGGAAGCCTTCGTCCAAACCCTGACCGCCTGCCGCCTCTGCCCCAGGCTCGTGGCCTGGCGGGAGGAGGTCGT
GGGGAGAAAGCGGGCCTTCCGGGGCGAGCCCTACTGGGCGAGGCCGGTTCCGGGCTTTGGCGACCCCGAGGCCAGGATCC
TCCTCTTCGGCCTCGCCCCCGGGGCCCACGGCTCCAACCGCACGGGCCGCCCCTTCACCGGGGACGCCTCCGGGGCCTTC
CTCTACCCCTTGCTCCATGAGGCGGGCCTCTCCAGCAAGCCGGAAAGCCTTCCCGGGGACGACCTCAGGCTCTACGGGGT
CTACCTCACCGCGGCGGTGCGCTGCGCCCCGCCCAAGAACAAGCCCACCCCCGAGGAGCTCCGCGCCTGCGCCCGCTGGA
CGGAGGTGGAGCTCGGCCTCCTCCCCGAGGTGCGGGTCTACGTGGCCCTGGGGAGGATCGCCCTCGAGGCCCTCCTCGCC
CACTTCGGCCTGAGGAAGAGCGCCCACCCCTTCCGCCACGGGGCCCACTACCCCCTTCCCGGGGGAAGGCACCTCCTCGC
GAGCTACCACGTCTCCCGGCAGAACACCCAGACGGGCAGGCTCACCCGGGAGATGTTCCTGGAGGTCCTGATGGAGGCTA
AACGCCTCGCCGGGCTTTGA

Upstream 100 bases:

>100_bases
ACCCCACCCACACCCGGCGCGTCCTCTACCAGCACCTAAGGATGCTCTGGGAGAAGCAGGAGGAGAGGCCCAGGAAGAAG
CACGACAACATCCCCCTGTG

Downstream 100 bases:

>100_bases
GCCAGGAGAGGAGGTCCTCGTAGTCCAAGGTGTTGAGCACCCGCTCGGGGCCGATCCAGGCCCGTTGCGCCGTGCCCACG
GCGAGCTCCATGAAGCGGAG

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MDREAFVQTLTACRLCPRLVAWREEVVGRKRAFRGEPYWARPVPGFGDPEARILLFGLAPGAHGSNRTGRPFTGDASGAF
LYPLLHEAGLSSKPESLPGDDLRLYGVYLTAAVRCAPPKNKPTPEELRACARWTEVELGLLPEVRVYVALGRIALEALLA
HFGLRKSAHPFRHGAHYPLPGGRHLLASYHVSRQNTQTGRLTREMFLEVLMEAKRLAGL

Sequences:

>Translated_219_residues
MDREAFVQTLTACRLCPRLVAWREEVVGRKRAFRGEPYWARPVPGFGDPEARILLFGLAPGAHGSNRTGRPFTGDASGAF
LYPLLHEAGLSSKPESLPGDDLRLYGVYLTAAVRCAPPKNKPTPEELRACARWTEVELGLLPEVRVYVALGRIALEALLA
HFGLRKSAHPFRHGAHYPLPGGRHLLASYHVSRQNTQTGRLTREMFLEVLMEAKRLAGL
>Mature_219_residues
MDREAFVQTLTACRLCPRLVAWREEVVGRKRAFRGEPYWARPVPGFGDPEARILLFGLAPGAHGSNRTGRPFTGDASGAF
LYPLLHEAGLSSKPESLPGDDLRLYGVYLTAAVRCAPPKNKPTPEELRACARWTEVELGLLPEVRVYVALGRIALEALLA
HFGLRKSAHPFRHGAHYPLPGGRHLLASYHVSRQNTQTGRLTREMFLEVLMEAKRLAGL

Specific function: Unknown

COG id: COG1573

COG function: function code L; Uracil-DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML1105 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: NA

Molecular weight: Translated: 24286; Mature: 24286

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDREAFVQTLTACRLCPRLVAWREEVVGRKRAFRGEPYWARPVPGFGDPEARILLFGLAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCC
GAHGSNRTGRPFTGDASGAFLYPLLHEAGLSSKPESLPGDDLRLYGVYLTAAVRCAPPKN
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHEECCCCC
KPTPEELRACARWTEVELGLLPEVRVYVALGRIALEALLAHFGLRKSAHPFRHGAHYPLP
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCC
GGRHLLASYHVSRQNTQTGRLTREMFLEVLMEAKRLAGL
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDREAFVQTLTACRLCPRLVAWREEVVGRKRAFRGEPYWARPVPGFGDPEARILLFGLAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCC
GAHGSNRTGRPFTGDASGAFLYPLLHEAGLSSKPESLPGDDLRLYGVYLTAAVRCAPPKN
CCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHEECCCCC
KPTPEELRACARWTEVELGLLPEVRVYVALGRIALEALLAHFGLRKSAHPFRHGAHYPLP
CCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCC
GGRHLLASYHVSRQNTQTGRLTREMFLEVLMEAKRLAGL
CCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]