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The map label for this gene is speB1 [H]

Identifier: 55981098

GI number: 55981098

Start: 1072006

End: 1072887

Strand: Reverse

Name: speB1 [H]

Synonym: TTHA1129

Alternate gene names: 55981098

Gene position: 1072887-1072006 (Counterclockwise)

Preceding gene: 55981099

Following gene: 55981097

Centisome position: 58.0

GC content: 69.27

Gene sequence:

>882_bases
ATGCGCCTCGTCTTCGGCGAAAAGGACACCCCTTACGAGGAGGCGCGGGTCGTCGTCCTGCCCGTGCCCTACGACCTCTC
CCTCTCCTTCCTCCCGGGGGCCCGGAGGGGCCCCGAGGCCATCCTCCTGGCGAGCCGCGAGCTTGAGCCCTTTCTTTTGG
AGCTCGGCGCCGCCCCCGAGGAGGTGGGGATCCACGCGGCCGAGCCCGTGCCCTGGGTGGCGGGGATGGCCGAGGAAAGC
CACCGCCTGATCCGGGAGGAGGCCCTAAGGCACCTCCGGGCGGGGAAGTGGGTGGTGGCCCTGGGCGGGGACCACTCCGT
CACCCACCCCCTGGTCCAGGCCCACCGGGAGGCCCTGGGGGATTTTTCCCTCCTTCACGTGGACGCCCACGCCGACCTCT
ACCCGGAGTGGCAGGGCTCGGTCTACTCCCACGCAAGCCCCTTCTACCGCCTCCTCACGGAGGGGTTTCCCCTGGTCCAG
GTGGGGATCCGGGCCATGGACCGAGACTCCCTGCGCTTGGCCCGAAAAAAGGGCGTGGCCCTCTTTCCCGCCCACCGGAT
CCACCGGGAGGGGCTTCCCCTGGACGAGATCCTTAGGGCCCTGGGGAAGCGGGTCTACATCAGCCTGGACTTTGACGCCC
TGGACCCCTCCCTCATGCCCAGCGTGGGCACGCCCCTTCCCGGGGGGCTTTCCTACCGCCAGGTGGTGGACCTCCTCGAG
GCCGTCTTCCGCGAGAAGGAGGTGGTGGGGATGGACTTCGTGGAGCTCTCCCCGAACGGCCAGTTCCACGCCGAGATGAC
CGCGGCCCAGCTCGTCTACCACGCCATCGGCCTGAAAGGGCTTCAGGCGGGCTGGCTTTCCCGGGAGGTGGACCACATTT
AG

Upstream 100 bases:

>100_bases
CGAGCACATCCGCGTCCGGGACTTTGAGCGGGGGGTGCAGGCCCTCCTGCGCCTCTTGGAGCTTTTCTTCCTGGGCCGGT
AGGCCTTACCCTCTTGGCGT

Downstream 100 bases:

>100_bases
CCCGAGGGGTTTCCCCTTAGCCTGGGGGCATGCGCCTCGGGCTTTGGCTTTCCTTCCTCCTCCTCCCGGCCCTGGCCCAG
GTCCTCACCCTCCCTGACCT

Product: agmatinase SpeB

Products: NA

Alternate protein names: Agmatine ureohydrolase 1; AUH 1 [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MRLVFGEKDTPYEEARVVVLPVPYDLSLSFLPGARRGPEAILLASRELEPFLLELGAAPEEVGIHAAEPVPWVAGMAEES
HRLIREEALRHLRAGKWVVALGGDHSVTHPLVQAHREALGDFSLLHVDAHADLYPEWQGSVYSHASPFYRLLTEGFPLVQ
VGIRAMDRDSLRLARKKGVALFPAHRIHREGLPLDEILRALGKRVYISLDFDALDPSLMPSVGTPLPGGLSYRQVVDLLE
AVFREKEVVGMDFVELSPNGQFHAEMTAAQLVYHAIGLKGLQAGWLSREVDHI

Sequences:

>Translated_293_residues
MRLVFGEKDTPYEEARVVVLPVPYDLSLSFLPGARRGPEAILLASRELEPFLLELGAAPEEVGIHAAEPVPWVAGMAEES
HRLIREEALRHLRAGKWVVALGGDHSVTHPLVQAHREALGDFSLLHVDAHADLYPEWQGSVYSHASPFYRLLTEGFPLVQ
VGIRAMDRDSLRLARKKGVALFPAHRIHREGLPLDEILRALGKRVYISLDFDALDPSLMPSVGTPLPGGLSYRQVVDLLE
AVFREKEVVGMDFVELSPNGQFHAEMTAAQLVYHAIGLKGLQAGWLSREVDHI
>Mature_293_residues
MRLVFGEKDTPYEEARVVVLPVPYDLSLSFLPGARRGPEAILLASRELEPFLLELGAAPEEVGIHAAEPVPWVAGMAEES
HRLIREEALRHLRAGKWVVALGGDHSVTHPLVQAHREALGDFSLLHVDAHADLYPEWQGSVYSHASPFYRLLTEGFPLVQ
VGIRAMDRDSLRLARKKGVALFPAHRIHREGLPLDEILRALGKRVYISLDFDALDPSLMPSVGTPLPGGLSYRQVVDLLE
AVFREKEVVGMDFVELSPNGQFHAEMTAAQLVYHAIGLKGLQAGWLSREVDHI

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=267, Percent_Identity=33.7078651685393, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI10947139, Length=227, Percent_Identity=29.0748898678414, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4502215, Length=265, Percent_Identity=27.5471698113208, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1789306, Length=263, Percent_Identity=31.1787072243346, Blast_Score=119, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325146, Length=218, Percent_Identity=25.2293577981651, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24638886, Length=205, Percent_Identity=29.2682926829268, Blast_Score=81, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 32484; Mature: 32484

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLVFGEKDTPYEEARVVVLPVPYDLSLSFLPGARRGPEAILLASRELEPFLLELGAAPE
CEEEECCCCCCHHHCEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHCCCHH
EVGIHAAEPVPWVAGMAEESHRLIREEALRHLRAGKWVVALGGDHSVTHPLVQAHREALG
HCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHC
DFSLLHVDAHADLYPEWQGSVYSHASPFYRLLTEGFPLVQVGIRAMDRDSLRLARKKGVA
CEEEEEEECCCCCCCCCCCCCHHCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCE
LFPAHRIHREGLPLDEILRALGKRVYISLDFDALDPSLMPSVGTPLPGGLSYRQVVDLLE
EECHHHHHHCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AVFREKEVVGMDFVELSPNGQFHAEMTAAQLVYHAIGLKGLQAGWLSREVDHI
HHHHCCHHCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLVFGEKDTPYEEARVVVLPVPYDLSLSFLPGARRGPEAILLASRELEPFLLELGAAPE
CEEEECCCCCCHHHCEEEEEECCCCCEEEECCCCCCCCCEEEEECCCCCHHHHHHCCCHH
EVGIHAAEPVPWVAGMAEESHRLIREEALRHLRAGKWVVALGGDHSVTHPLVQAHREALG
HCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHC
DFSLLHVDAHADLYPEWQGSVYSHASPFYRLLTEGFPLVQVGIRAMDRDSLRLARKKGVA
CEEEEEEECCCCCCCCCCCCCHHCCHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHCCCE
LFPAHRIHREGLPLDEILRALGKRVYISLDFDALDPSLMPSVGTPLPGGLSYRQVVDLLE
EECHHHHHHCCCCHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
AVFREKEVVGMDFVELSPNGQFHAEMTAAQLVYHAIGLKGLQAGWLSREVDHI
HHHHCCHHCCCEEEEECCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]