Click here to switch to the map view.

The map label for this gene is accB [H]

Identifier: 55981093

GI number: 55981093

Start: 1068866

End: 1069363

Strand: Reverse

Name: accB [H]

Synonym: TTHA1124

Alternate gene names: 55981093

Gene position: 1069363-1068866 (Counterclockwise)

Preceding gene: 55981094

Following gene: 55981092

Centisome position: 57.81

GC content: 70.28

Gene sequence:

>498_bases
ATGACGCCGAAGGAGCTGAAGCAGATCCTGCAAGCCTTGGTGGAGCACGGGGTGAACGAGCTCACCCTGGAGACCCCGGA
CTACAAGCTCACCGTGCGGCGGGGCGGGGAGGTGCAGGTGGTGGGCGTCCCCCAGGTCCAGGCCCCCGTGCTTGTGCCCC
CCCCGGAGGTGCCGGCCCCGCCCCCGCCCGCGCCGGCGGCCCCGGCGGCGGAGCCCCAGCCCCAGGCCAAGGCGGAGCCC
CAGGACGACTGCCCGGGGTGCGTGGAGGTCCGGGCCCCCATCGTGGGCACCTTCTACCGGGCTCCGGCCCCGGACGCTCC
TCCCTACGTGAAGGAGGGGGACCGGGTGGAGAAGGGGCAGGTCCTCTGCATCATTGAGGCCATGAAGCTCATGAACGAGA
TCGAGTCCGAGGTCTCGGGGATCGTCAAGAAGATCCTGGTGGAGAACGGGGAGCCGGTGGAGTACGGCCAGCCCCTCTTC
CTTATCCAGCCGGTATGA

Upstream 100 bases:

>100_bases
GCCTAGGCCGCCTGGGGGGCCGCCCCCTCTACGGGATTTTGATGCGGTGCAGAAATCCGTAAGGGGTGTATGGGGTAAGC
TTTTCCCGCGAGGTGCACCG

Downstream 100 bases:

>100_bases
AGAAGGTCCTGATCGCCAACCGGGGTGAGATCGCCTTAAGGATCATCCGGGCGGCCCGGGAGCTCGGGATCAAGACGGTG
GTGGCCCACTCCACCGCCGA

Product: acetyl-CoA carboxylase, biotin carboxyl carrier protein

Products: Malonyl-CoA; malonyl-CoA; phosphate; ADP [C]

Alternate protein names: BCCP [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTPKELKQILQALVEHGVNELTLETPDYKLTVRRGGEVQVVGVPQVQAPVLVPPPEVPAPPPPAPAAPAAEPQPQAKAEP
QDDCPGCVEVRAPIVGTFYRAPAPDAPPYVKEGDRVEKGQVLCIIEAMKLMNEIESEVSGIVKKILVENGEPVEYGQPLF
LIQPV

Sequences:

>Translated_165_residues
MTPKELKQILQALVEHGVNELTLETPDYKLTVRRGGEVQVVGVPQVQAPVLVPPPEVPAPPPPAPAAPAAEPQPQAKAEP
QDDCPGCVEVRAPIVGTFYRAPAPDAPPYVKEGDRVEKGQVLCIIEAMKLMNEIESEVSGIVKKILVENGEPVEYGQPLF
LIQPV
>Mature_164_residues
TPKELKQILQALVEHGVNELTLETPDYKLTVRRGGEVQVVGVPQVQAPVLVPPPEVPAPPPPAPAAPAAEPQPQAKAEPQ
DDCPGCVEVRAPIVGTFYRAPAPDAPPYVKEGDRVEKGQVLCIIEAMKLMNEIESEVSGIVKKILVENGEPVEYGQPLFL
IQPV

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0511

COG function: function code I; Biotin carboxyl carrier protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotinyl-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789653, Length=166, Percent_Identity=37.3493975903614, Blast_Score=109, Evalue=8e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001249
- InterPro:   IPR001882
- InterPro:   IPR000089
- InterPro:   IPR011053 [H]

Pfam domain/function: PF00364 Biotin_lipoyl [H]

EC number: NA

Molecular weight: Translated: 17734; Mature: 17603

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPKELKQILQALVEHGVNELTLETPDYKLTVRRGGEVQVVGVPQVQAPVLVPPPEVPAP
CCHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEEECCCCCCCEEECCCCCCCC
PPPAPAAPAAEPQPQAKAEPQDDCPGCVEVRAPIVGTFYRAPAPDAPPYVKEGDRVEKGQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEHEECCCCCCCCCCCCCCCCCCCCC
VLCIIEAMKLMNEIESEVSGIVKKILVENGEPVEYGQPLFLIQPV
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TPKELKQILQALVEHGVNELTLETPDYKLTVRRGGEVQVVGVPQVQAPVLVPPPEVPAP
CHHHHHHHHHHHHHCCCCEEEEECCCEEEEEECCCEEEEEECCCCCCCEEECCCCCCCC
PPPAPAAPAAEPQPQAKAEPQDDCPGCVEVRAPIVGTFYRAPAPDAPPYVKEGDRVEKGQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEHEECCCCCCCCCCCCCCCCCCCCC
VLCIIEAMKLMNEIESEVSGIVKKILVENGEPVEYGQPLFLIQPV
EEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; HCO3-; Proton; acetyl-CoA; ATP [C]

Specific reaction: acetyl-CoA = malonyl-CoA HCO3- + Proton + acetyl-CoA + ATP = malonyl-CoA + phosphate + ADP [C]

General reaction: Ligases; Forming Carbon-Carbon Bonds; acetyl-CoA carboxylase Reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8102363; 11759840 [H]