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The map label for this gene is pheA [H]

Identifier: 55981073

GI number: 55981073

Start: 1051201

End: 1052043

Strand: Direct

Name: pheA [H]

Synonym: TTHA1104

Alternate gene names: 55981073

Gene position: 1051201-1052043 (Clockwise)

Preceding gene: 55981068

Following gene: 55981076

Centisome position: 56.83

GC content: 68.92

Gene sequence:

>843_bases
ATGGGAACCATGAGGATCGCCTTCCAGGGCACGGCGGGGGCCTACAGCGAGGAGGCCTTGCTCAAGGTCTTCCCCGAGGC
GAAGCCCGTGGGCTTTCCCACCTTTCACCAGGTCTTTGAGGCGGTGGAGGCGGGCGAGGCGGAGCTTGGGGTGGTGCCGG
TGGAGAACACCACGGCGGGGAGCATCAACCAGACCTACGACCTCCTCCTGGAGAGCGACCTCCACGTGGTGGGGGAGATC
GTCCACCGGGTGGAGCACTGCCTCCTCGCCCCCAAGGGCACAACGCTCAAGGACCTGCACGCGGTGAAGAGCCACCCCCA
GGCCCTGGCCCAGTGCGACGGCTTCCTCGCCCGGATGCGCCTCACCCCCATCCCCGTCTTTGACACCGCCGGGGCGGCCA
AGGAGCTCGCCGAGCACCCGGAGCCGGGCCTCGCCGCCATCGCCTCCAGGCGGGCGGCGGAGCTTTACGGCCTCGAGGTC
CTGGCGGAAAACATCGAGGACTACCCCCACAACTACACCCGCTTCTTCGTCATCGGGCACAAGGAGCCCCCGAGGGGCCA
GGGGCCCTACAAGACGAGCATCGTCTTCGCCGTCCGGCACCGGCCCGGGGGGCTTTTGGAGGCGCTTTCCGTCTTCGCCG
AGGCGGGGGTGAACCTCACCAAGCTGGAGTCCAGGCCCCGGAGGGACAAGCCCTTCAGCTACCTCTTCTACCTGGACCTG
GAGGGGCACCTGGAGGACCCCGGGCCCGCCCAGGCCCTCCTCCGCCTCCTCAGGCGGGTGGCCTTCCTCAAGGTCTTGGG
CTCCTACCCCGCCCACGCCAACGGGGGCGTTAGCGCACCTTAA

Upstream 100 bases:

>100_bases
GGCGGTTCCACGCCTCGGGCTCTTGGACTTCGGCAAGCTCCCACACCCCTCAAGCCTACATGGCCCGGACCCGGTCTTCC
AGAAGGCGGGCCCGTGTACC

Downstream 100 bases:

>100_bases
GCCCCCGCAGGAAGAGGTTCCGGTCCTCCGGAGGGGCGTAGAGGTCGTTGAGGAAGGCGAGGACGAGCACGCCCCGCCCC
GTGGTCCGGACCCGCACCTC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MGTMRIAFQGTAGAYSEEALLKVFPEAKPVGFPTFHQVFEAVEAGEAELGVVPVENTTAGSINQTYDLLLESDLHVVGEI
VHRVEHCLLAPKGTTLKDLHAVKSHPQALAQCDGFLARMRLTPIPVFDTAGAAKELAEHPEPGLAAIASRRAAELYGLEV
LAENIEDYPHNYTRFFVIGHKEPPRGQGPYKTSIVFAVRHRPGGLLEALSVFAEAGVNLTKLESRPRRDKPFSYLFYLDL
EGHLEDPGPAQALLRLLRRVAFLKVLGSYPAHANGGVSAP

Sequences:

>Translated_280_residues
MGTMRIAFQGTAGAYSEEALLKVFPEAKPVGFPTFHQVFEAVEAGEAELGVVPVENTTAGSINQTYDLLLESDLHVVGEI
VHRVEHCLLAPKGTTLKDLHAVKSHPQALAQCDGFLARMRLTPIPVFDTAGAAKELAEHPEPGLAAIASRRAAELYGLEV
LAENIEDYPHNYTRFFVIGHKEPPRGQGPYKTSIVFAVRHRPGGLLEALSVFAEAGVNLTKLESRPRRDKPFSYLFYLDL
EGHLEDPGPAQALLRLLRRVAFLKVLGSYPAHANGGVSAP
>Mature_279_residues
GTMRIAFQGTAGAYSEEALLKVFPEAKPVGFPTFHQVFEAVEAGEAELGVVPVENTTAGSINQTYDLLLESDLHVVGEIV
HRVEHCLLAPKGTTLKDLHAVKSHPQALAQCDGFLARMRLTPIPVFDTAGAAKELAEHPEPGLAAIASRRAAELYGLEVL
AENIEDYPHNYTRFFVIGHKEPPRGQGPYKTSIVFAVRHRPGGLLEALSVFAEAGVNLTKLESRPRRDKPFSYLFYLDLE
GHLEDPGPAQALLRLLRRVAFLKVLGSYPAHANGGVSAP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=274, Percent_Identity=39.051094890511, Blast_Score=177, Evalue=9e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30449; Mature: 30318

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTMRIAFQGTAGAYSEEALLKVFPEAKPVGFPTFHQVFEAVEAGEAELGVVPVENTTAG
CCCEEEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCC
SINQTYDLLLESDLHVVGEIVHRVEHCLLAPKGTTLKDLHAVKSHPQALAQCDGFLARMR
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHC
LTPIPVFDTAGAAKELAEHPEPGLAAIASRRAAELYGLEVLAENIEDYPHNYTRFFVIGH
CCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
KEPPRGQGPYKTSIVFAVRHRPGGLLEALSVFAEAGVNLTKLESRPRRDKPFSYLFYLDL
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEEE
EGHLEDPGPAQALLRLLRRVAFLKVLGSYPAHANGGVSAP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
GTMRIAFQGTAGAYSEEALLKVFPEAKPVGFPTFHQVFEAVEAGEAELGVVPVENTTAG
CCEEEEEECCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCC
SINQTYDLLLESDLHVVGEIVHRVEHCLLAPKGTTLKDLHAVKSHPQALAQCDGFLARMR
CCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHC
LTPIPVFDTAGAAKELAEHPEPGLAAIASRRAAELYGLEVLAENIEDYPHNYTRFFVIGH
CCCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEC
KEPPRGQGPYKTSIVFAVRHRPGGLLEALSVFAEAGVNLTKLESRPRRDKPFSYLFYLDL
CCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCEEEEEEEEE
EGHLEDPGPAQALLRLLRRVAFLKVLGSYPAHANGGVSAP
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]