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The map label for this gene is mraY [H]

Identifier: 55981050

GI number: 55981050

Start: 1027965

End: 1028822

Strand: Direct

Name: mraY [H]

Synonym: TTHA1081

Alternate gene names: 55981050

Gene position: 1027965-1028822 (Clockwise)

Preceding gene: 55981049

Following gene: 55981051

Centisome position: 55.57

GC content: 72.03

Gene sequence:

>858_bases
ATGGTCCTAGCCACCGCCCTTCTTCTCGCCTGGGTCCTCACGGCCTTCTGGATCGCCCTGGCCCCCGGCCTGGGCCTGGG
AAAGCGGGTCCGCGCCGAGGGCCCTGAGGCCCACCTCGCCAAGGCGGGCACCCCCAGCATGGGCGGGGTGGCCTTCCTCC
TGGCCGCGGCCCTGGCCTACGGGCTTCACGGGGGGGACGCCTTCAGGGGGCTTTGGCTCCTCGGCCTCGGCTTCGCCCTC
CTCGGGGCGGTGGACGACCTGGCGGGAAGCCGCCTGAGGCCCCTCAGGGCCCGGGAGAAGCTCCTCGCCCAGGGGGTCAT
GGGCCTCGTCTTCGCCCTCTGGGCCTCGAGGCTCGTGAACTACACCCCCTGGCCCTGGCTGGACGTCCTCCTCATCCTCC
TCGCCGTGGTGGGGGCGGCCAACGCCTTCAACTTCACCGACGGCCTGGACGGCCTCCTCGCCTCGGTGACCGCCGTGATC
CTCCTGCCCTTCTACCCCTACCCCCTGGCCCAGGCCCTACTGGGCGGGGTGCTGGGCTTCCTCTGGCACAACGCCCCCCG
GGCCAAGGTCTTCATGGGGGACACGGGGAGCCAGGCCTTGGGGGCCATGGTGGCGGGGCTCTTCGTCCTCACGGGGAAGC
TCTGGCTCCTGCCCCTCGCCGCCATCGTCCCCGTGGTGGAGGTGCTCTCGGTGGTGGCCCAGGTGGCCTACTTCCGGCGC
ACGGGGCGGCGCCTCCTCCGCATGAGCCCCCTCCACCACCACTTTGAGCTCCTCGGCTGGGACGAGGCCAAGATCGTCTT
CCGCTTCGCCGTGGTCACCGCCTTGGCCGTGGCCCTGGCCTTCGGAGGTGGGGGATGA

Upstream 100 bases:

>100_bases
CCGGCCTCACCCCCCTGGGCCCGGCGGAGGACCTCGCCGCCTGGGAGGACTCCCTCTACCTGAGCCCCGGGGAACGGACC
CTGCGCTGCGGGGAGGTGCC

Downstream 100 bases:

>100_bases
GGCTCGTCTACGGCCTGGGACGGAGCGGCCTCGGCGTCCTCCGCTTCCTGAGGAAACGGGGGCTTCCCGCCCGCTTCTAC
GACGACCGCCCCCGGGAAGA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MVLATALLLAWVLTAFWIALAPGLGLGKRVRAEGPEAHLAKAGTPSMGGVAFLLAAALAYGLHGGDAFRGLWLLGLGFAL
LGAVDDLAGSRLRPLRAREKLLAQGVMGLVFALWASRLVNYTPWPWLDVLLILLAVVGAANAFNFTDGLDGLLASVTAVI
LLPFYPYPLAQALLGGVLGFLWHNAPRAKVFMGDTGSQALGAMVAGLFVLTGKLWLLPLAAIVPVVEVLSVVAQVAYFRR
TGRRLLRMSPLHHHFELLGWDEAKIVFRFAVVTALAVALAFGGGG

Sequences:

>Translated_285_residues
MVLATALLLAWVLTAFWIALAPGLGLGKRVRAEGPEAHLAKAGTPSMGGVAFLLAAALAYGLHGGDAFRGLWLLGLGFAL
LGAVDDLAGSRLRPLRAREKLLAQGVMGLVFALWASRLVNYTPWPWLDVLLILLAVVGAANAFNFTDGLDGLLASVTAVI
LLPFYPYPLAQALLGGVLGFLWHNAPRAKVFMGDTGSQALGAMVAGLFVLTGKLWLLPLAAIVPVVEVLSVVAQVAYFRR
TGRRLLRMSPLHHHFELLGWDEAKIVFRFAVVTALAVALAFGGGG
>Mature_285_residues
MVLATALLLAWVLTAFWIALAPGLGLGKRVRAEGPEAHLAKAGTPSMGGVAFLLAAALAYGLHGGDAFRGLWLLGLGFAL
LGAVDDLAGSRLRPLRAREKLLAQGVMGLVFALWASRLVNYTPWPWLDVLLILLAVVGAANAFNFTDGLDGLLASVTAVI
LLPFYPYPLAQALLGGVLGFLWHNAPRAKVFMGDTGSQALGAMVAGLFVLTGKLWLLPLAAIVPVVEVLSVVAQVAYFRR
TGRRLLRMSPLHHHFELLGWDEAKIVFRFAVVTALAVALAFGGGG

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=323, Percent_Identity=34.3653250773994, Blast_Score=137, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 30135; Mature: 30135

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: PS01347 MRAY_1 ; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLATALLLAWVLTAFWIALAPGLGLGKRVRAEGPEAHLAKAGTPSMGGVAFLLAAALAY
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHH
GLHGGDAFRGLWLLGLGFALLGAVDDLAGSRLRPLRAREKLLAQGVMGLVFALWASRLVN
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
YTPWPWLDVLLILLAVVGAANAFNFTDGLDGLLASVTAVILLPFYPYPLAQALLGGVLGF
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LWHNAPRAKVFMGDTGSQALGAMVAGLFVLTGKLWLLPLAAIVPVVEVLSVVAQVAYFRR
HHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGRRLLRMSPLHHHFELLGWDEAKIVFRFAVVTALAVALAFGGGG
HHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVLATALLLAWVLTAFWIALAPGLGLGKRVRAEGPEAHLAKAGTPSMGGVAFLLAAALAY
CHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCHHHHHCCCCCCCCHHHHHHHHHHHH
GLHGGDAFRGLWLLGLGFALLGAVDDLAGSRLRPLRAREKLLAQGVMGLVFALWASRLVN
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
YTPWPWLDVLLILLAVVGAANAFNFTDGLDGLLASVTAVILLPFYPYPLAQALLGGVLGF
CCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
LWHNAPRAKVFMGDTGSQALGAMVAGLFVLTGKLWLLPLAAIVPVVEVLSVVAQVAYFRR
HHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGRRLLRMSPLHHHFELLGWDEAKIVFRFAVVTALAVALAFGGGG
HHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA