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The map label for this gene is ffh [H]

Identifier: 55981005

GI number: 55981005

Start: 983018

End: 984322

Strand: Reverse

Name: ffh [H]

Synonym: TTHA1036

Alternate gene names: 55981005

Gene position: 984322-983018 (Counterclockwise)

Preceding gene: 55981006

Following gene: 55981004

Centisome position: 53.21

GC content: 70.57

Gene sequence:

>1305_bases
ATGTTCCAGCAGCTAGCCGCACGACTCCAGGAGGCCATTGACCGGCTCAGGGGCCGGGGCCGGATCACGGAGGAGGACCT
GAAGGGGACCCTCCGGGAGATCCGCCGCGCCCTCATTGAGGCCGACGTGAACCTGGAGGTGGCCCGGGCCTTCGTGGAGG
AGGTGCGGGAGCGGGCTTTGGGGCGGAAGGTCCTGGAGAGCCTGACCCCGGCCGAGGTGGTCCTGGCCACGGTCTACGAG
GCCCTGAAGGAGGCCCTGGGCGGGGAGCCCAAGCACCCCCAGCTCAAGGACCGGAACGTCTGGTTCCTCGTGGGGCTCCA
GGGGTCGGGGAAGACCACCACCGCCGCCAAGCTCGCCCTCTACTACAAGGGGAAGGGGCGGCGTCCCCTCCTGGTGGCGG
CGGACACCCAGCGCCCGGCGGCGCGGGAGCAGCTCCGCGTCCTGGGGGAGAAGGTGGGGGTGCCGGTCCTCGAGGTCCAG
GACGGGGAAAGCCCCGAGTCCATCCGGCGGCGGGTGGAGGAGCGGGCCCGCCTGGAGGTGCGGGACCTCGTCCTGGTGGA
CACCGCCGGCCGCCTCCAGATTGACGAGCGCCTCATGGAGGAGCTCGTGCGCCTCAAGGCGGCGCTGCGCCCCGACGAGG
TCCTCCTCGTCCTGGACGCCATGACGGGCCAGGAGGCCCTCTCCGTGGCCCAGGCCTTTGACGAGCGGGTGGGGGTCACG
GGCCTCGTCCTCACCAAGCTGGACGGGGACGCCCGGGGCGGGGCCGCCCTCTCCGCGCGGCGGGTCACGGGCAAGCCCAT
CTACTTCGCCGGGGTTTCCGAGCGGCCGGAGGGCTTGGAGCCCTTCTACCCCGACCGCCTCGCGGGCAGGATCCTCGGCA
TGGGGGACGTGGCCACCCTGGCGGAAAAGGTGCGCCAGGCGGGCCTCGAGGCCGAGGCGCCCAAGTCCGCCAAGGAGCTC
ACCCTGGAGGACTTCCTCAAGCAGATGCAAAACCTCAAGCGGCTGGGTTCCTTCTCCGAGCTCCTAAAGCTTCTTCCCGG
GGTGGGCCGGGCCCTGCCCCAGGGGTTCCAGGTGGACGAGCGGGCCTTCAAGCGCCTGGAGGCCATCGTCCTCTCCATGA
CCCCGGAGGAGCGCAAGGACCCCCGGATCCTCAACGCCTCCCGCAGGCGGCGCATCGCCAAAGGAAGCGGCACCACGGTT
CAGGAGGTCAACCGGCTGGTCAAGGCCTTTGAGGAAACCAAGGCCCTGATGAAGTCCCTGGAGCGCCGCAAGGGCCGGGG
ACTCATGGGAATGTTCAGGAGGTAA

Upstream 100 bases:

>100_bases
TAGCCCTCGAGGCCCGGTAAACACATCAGAAAAATTGCGGTTGACACGCTCAACCCCCTTGGTCTATCCTGGACCCCGGC
CTTAAGGGCCGGGGAGCCAT

Downstream 100 bases:

>100_bases
GCGCATGGTCAAGATCCGTCTGGCTCGGTTCGGTTCCAAGCACAACCCCCACTACCGCATCGTGGTCACCGACGCCCGCA
GGAAGCGGGACGGCAAGTAC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MFQQLAARLQEAIDRLRGRGRITEEDLKGTLREIRRALIEADVNLEVARAFVEEVRERALGRKVLESLTPAEVVLATVYE
ALKEALGGEPKHPQLKDRNVWFLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQRPAAREQLRVLGEKVGVPVLEVQ
DGESPESIRRRVEERARLEVRDLVLVDTAGRLQIDERLMEELVRLKAALRPDEVLLVLDAMTGQEALSVAQAFDERVGVT
GLVLTKLDGDARGGAALSARRVTGKPIYFAGVSERPEGLEPFYPDRLAGRILGMGDVATLAEKVRQAGLEAEAPKSAKEL
TLEDFLKQMQNLKRLGSFSELLKLLPGVGRALPQGFQVDERAFKRLEAIVLSMTPEERKDPRILNASRRRRIAKGSGTTV
QEVNRLVKAFEETKALMKSLERRKGRGLMGMFRR

Sequences:

>Translated_434_residues
MFQQLAARLQEAIDRLRGRGRITEEDLKGTLREIRRALIEADVNLEVARAFVEEVRERALGRKVLESLTPAEVVLATVYE
ALKEALGGEPKHPQLKDRNVWFLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQRPAAREQLRVLGEKVGVPVLEVQ
DGESPESIRRRVEERARLEVRDLVLVDTAGRLQIDERLMEELVRLKAALRPDEVLLVLDAMTGQEALSVAQAFDERVGVT
GLVLTKLDGDARGGAALSARRVTGKPIYFAGVSERPEGLEPFYPDRLAGRILGMGDVATLAEKVRQAGLEAEAPKSAKEL
TLEDFLKQMQNLKRLGSFSELLKLLPGVGRALPQGFQVDERAFKRLEAIVLSMTPEERKDPRILNASRRRRIAKGSGTTV
QEVNRLVKAFEETKALMKSLERRKGRGLMGMFRR
>Mature_434_residues
MFQQLAARLQEAIDRLRGRGRITEEDLKGTLREIRRALIEADVNLEVARAFVEEVRERALGRKVLESLTPAEVVLATVYE
ALKEALGGEPKHPQLKDRNVWFLVGLQGSGKTTTAAKLALYYKGKGRRPLLVAADTQRPAAREQLRVLGEKVGVPVLEVQ
DGESPESIRRRVEERARLEVRDLVLVDTAGRLQIDERLMEELVRLKAALRPDEVLLVLDAMTGQEALSVAQAFDERVGVT
GLVLTKLDGDARGGAALSARRVTGKPIYFAGVSERPEGLEPFYPDRLAGRILGMGDVATLAEKVRQAGLEAEAPKSAKEL
TLEDFLKQMQNLKRLGSFSELLKLLPGVGRALPQGFQVDERAFKRLEAIVLSMTPEERKDPRILNASRRRRIAKGSGTTV
QEVNRLVKAFEETKALMKSLERRKGRGLMGMFRR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=447, Percent_Identity=32.2147651006711, Blast_Score=228, Evalue=8e-60,
Organism=Homo sapiens, GI226371618, Length=352, Percent_Identity=34.0909090909091, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI89061728, Length=137, Percent_Identity=38.6861313868613, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI23308697, Length=297, Percent_Identity=31.3131313131313, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI295424842, Length=297, Percent_Identity=31.3131313131313, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1788963, Length=425, Percent_Identity=46.1176470588235, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1789874, Length=255, Percent_Identity=39.6078431372549, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=434, Percent_Identity=32.0276497695853, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI193206261, Length=291, Percent_Identity=32.6460481099656, Blast_Score=108, Evalue=5e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=425, Percent_Identity=32.2352941176471, Blast_Score=213, Evalue=6e-56,
Organism=Saccharomyces cerevisiae, GI6320498, Length=301, Percent_Identity=27.906976744186, Blast_Score=90, Evalue=6e-19,
Organism=Drosophila melanogaster, GI17647949, Length=443, Percent_Identity=31.6027088036117, Blast_Score=212, Evalue=3e-55,
Organism=Drosophila melanogaster, GI24641198, Length=282, Percent_Identity=29.4326241134752, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 48292; Mature: 48292

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQQLAARLQEAIDRLRGRGRITEEDLKGTLREIRRALIEADVNLEVARAFVEEVRERAL
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GRKVLESLTPAEVVLATVYEALKEALGGEPKHPQLKDRNVWFLVGLQGSGKTTTAAKLAL
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHEEEE
YYKGKGRRPLLVAADTQRPAAREQLRVLGEKVGVPVLEVQDGESPESIRRRVEERARLEV
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHH
RDLVLVDTAGRLQIDERLMEELVRLKAALRPDEVLLVLDAMTGQEALSVAQAFDERVGVT
HHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
GLVLTKLDGDARGGAALSARRVTGKPIYFAGVSERPEGLEPFYPDRLAGRILGMGDVATL
EEEEEECCCCCCCCCHHEECCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHH
AEKVRQAGLEAEAPKSAKELTLEDFLKQMQNLKRLGSFSELLKLLPGVGRALPQGFQVDE
HHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHH
RAFKRLEAIVLSMTPEERKDPRILNASRRRRIAKGSGTTVQEVNRLVKAFEETKALMKSL
HHHHHHHHHHHHCCCCCCCCCCHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ERRKGRGLMGMFRR
HHHCCCCHHHHCCC
>Mature Secondary Structure
MFQQLAARLQEAIDRLRGRGRITEEDLKGTLREIRRALIEADVNLEVARAFVEEVRERAL
CHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
GRKVLESLTPAEVVLATVYEALKEALGGEPKHPQLKDRNVWFLVGLQGSGKTTTAAKLAL
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCHHHHEEEE
YYKGKGRRPLLVAADTQRPAAREQLRVLGEKVGVPVLEVQDGESPESIRRRVEERARLEV
EEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHH
RDLVLVDTAGRLQIDERLMEELVRLKAALRPDEVLLVLDAMTGQEALSVAQAFDERVGVT
HHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCC
GLVLTKLDGDARGGAALSARRVTGKPIYFAGVSERPEGLEPFYPDRLAGRILGMGDVATL
EEEEEECCCCCCCCCHHEECCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHCCCCHHHHH
AEKVRQAGLEAEAPKSAKELTLEDFLKQMQNLKRLGSFSELLKLLPGVGRALPQGFQVDE
HHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHH
RAFKRLEAIVLSMTPEERKDPRILNASRRRRIAKGSGTTVQEVNRLVKAFEETKALMKSL
HHHHHHHHHHHHCCCCCCCCCCHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
ERRKGRGLMGMFRR
HHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9002524; 9695947; 10426959 [H]