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The map label for this gene is sdaAA [H]

Identifier: 55980998

GI number: 55980998

Start: 979221

End: 980075

Strand: Reverse

Name: sdaAA [H]

Synonym: TTHA1029

Alternate gene names: 55980998

Gene position: 980075-979221 (Counterclockwise)

Preceding gene: 55981000

Following gene: 55980989

Centisome position: 52.98

GC content: 71.93

Gene sequence:

>855_bases
ATGCCCCTTACCCTGAACCAGCTGGCCGAGCTTTCCGGCCGGGCCTCGGAGCACGTGCTCGCAGAGGAGGTGGAGGAAAC
GGGGACGCCTGCGGAGGAGATCCTGGCGCGCCTAAGGGAGCGCCTCGCCGTGATGCGGGACTCGGTGCGGCGGGGCCTCG
CTTCCGATGCCCCCAGCGTGGCGGGCCTGGTGGGGAAGAACGCCAAGACCCTCTGGGAGGCCCCTGACCCCCTGCAAGAC
CCCCTTCTCAAGCGGGTACAGGCCTACGCCATGGCCGTGAACGAGGAGAACGCCCGCATGGGGCGGATCGTGGCCGCCCC
CACGGCGGGGAGCGCGGGGACGCTTCCCGGGGCCCTTCTGGGCGTGGCGGACCACCTGGGGATCCCCGACGAGGAGCTCC
TCATGCCCTTGGTCCTCGCTGGGGGGGTGGCGAAGATGATCGGCCGGGTGATCCACATCGCCGGGGCGAGCGGGGGATGC
CAGGCCGAGATCGGCTCCAGCGCCGCCATGGCCGCGGCGGCCGTCACCGAGCTTTTAGGCGGCACCCCGGAGGCCTGCGC
CCACGCGGCGGCTTTGGCCCTGCAGAACACCCTGGGCTTGGTCTGCGACCCCGTGGGGGGGTTCGTGGAGGTGCCCTGCG
TGATGCGGAACGGCTTCTACGCCGTCCACGCGGTGAGCGCCGCCTCCATGGCCCTTGCGGGGATCCGGAGCGTGATCCCG
CCCGACGAGGTGGTCCTGGCCATGGCGGGCATCGGCCGCCTCCTCCCCCTGGAGCTCAAGGAAACCGGCCTGGGGGGCTT
GGCGGACACCCCCACAGGCCGGAGGCTGGCGGAAGAGGCGCTGAAGAAGACGTAG

Upstream 100 bases:

>100_bases
CGCCTCGAGGGCCGCCTTGAGCCCCAGGCGGAAGAGGGGGTGGTCGTCCGCCACAAGGAGGCGCACGCTTCCATCCTAAG
CCCCGGCGTATACTTAGGGC

Downstream 100 bases:

>100_bases
CCCTACTCCTCGCCTTTGGCGATGGGCACCCCCACCAGGTTGCCCCACTCGGTCCAGGAGCCGTCGTAGTTCTTCACGTG
GGGGTAGCCCAGGAGGTACT

Product: L-serine dehydratase subunit alpha

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MPLTLNQLAELSGRASEHVLAEEVEETGTPAEEILARLRERLAVMRDSVRRGLASDAPSVAGLVGKNAKTLWEAPDPLQD
PLLKRVQAYAMAVNEENARMGRIVAAPTAGSAGTLPGALLGVADHLGIPDEELLMPLVLAGGVAKMIGRVIHIAGASGGC
QAEIGSSAAMAAAAVTELLGGTPEACAHAAALALQNTLGLVCDPVGGFVEVPCVMRNGFYAVHAVSAASMALAGIRSVIP
PDEVVLAMAGIGRLLPLELKETGLGGLADTPTGRRLAEEALKKT

Sequences:

>Translated_284_residues
MPLTLNQLAELSGRASEHVLAEEVEETGTPAEEILARLRERLAVMRDSVRRGLASDAPSVAGLVGKNAKTLWEAPDPLQD
PLLKRVQAYAMAVNEENARMGRIVAAPTAGSAGTLPGALLGVADHLGIPDEELLMPLVLAGGVAKMIGRVIHIAGASGGC
QAEIGSSAAMAAAAVTELLGGTPEACAHAAALALQNTLGLVCDPVGGFVEVPCVMRNGFYAVHAVSAASMALAGIRSVIP
PDEVVLAMAGIGRLLPLELKETGLGGLADTPTGRRLAEEALKKT
>Mature_283_residues
PLTLNQLAELSGRASEHVLAEEVEETGTPAEEILARLRERLAVMRDSVRRGLASDAPSVAGLVGKNAKTLWEAPDPLQDP
LLKRVQAYAMAVNEENARMGRIVAAPTAGSAGTLPGALLGVADHLGIPDEELLMPLVLAGGVAKMIGRVIHIAGASGGCQ
AEIGSSAAMAAAAVTELLGGTPEACAHAAALALQNTLGLVCDPVGGFVEVPCVMRNGFYAVHAVSAASMALAGIRSVIPP
DEVVLAMAGIGRLLPLELKETGLGGLADTPTGRRLAEEALKKT

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=248, Percent_Identity=37.9032258064516, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1788116, Length=198, Percent_Identity=40.4040404040404, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789161, Length=256, Percent_Identity=36.328125, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005130
- InterPro:   IPR004642 [H]

Pfam domain/function: PF03313 SDH_alpha [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 29035; Mature: 28904

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLTLNQLAELSGRASEHVLAEEVEETGTPAEEILARLRERLAVMRDSVRRGLASDAPSV
CCCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
AGLVGKNAKTLWEAPDPLQDPLLKRVQAYAMAVNEENARMGRIVAAPTAGSAGTLPGALL
HHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCHHHH
GVADHLGIPDEELLMPLVLAGGVAKMIGRVIHIAGASGGCQAEIGSSAAMAAAAVTELLG
HHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHC
GTPEACAHAAALALQNTLGLVCDPVGGFVEVPCVMRNGFYAVHAVSAASMALAGIRSVIP
CCHHHHHHHHHHHHHHHHHHEECCCCCCEECCHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PDEVVLAMAGIGRLLPLELKETGLGGLADTPTGRRLAEEALKKT
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
PLTLNQLAELSGRASEHVLAEEVEETGTPAEEILARLRERLAVMRDSVRRGLASDAPSV
CCCHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
AGLVGKNAKTLWEAPDPLQDPLLKRVQAYAMAVNEENARMGRIVAAPTAGSAGTLPGALL
HHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEEECCCCCCCCCCCHHHH
GVADHLGIPDEELLMPLVLAGGVAKMIGRVIHIAGASGGCQAEIGSSAAMAAAAVTELLG
HHHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHHHHHHHHHC
GTPEACAHAAALALQNTLGLVCDPVGGFVEVPCVMRNGFYAVHAVSAASMALAGIRSVIP
CCHHHHHHHHHHHHHHHHHHEECCCCCCEECCHHHHCCCHHHHHHHHHHHHHHHHHHCCC
PDEVVLAMAGIGRLLPLELKETGLGGLADTPTGRRLAEEALKKT
HHHHHHHHHHCCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]