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The map label for this gene is xerD [H]

Identifier: 55980943

GI number: 55980943

Start: 917491

End: 918432

Strand: Reverse

Name: xerD [H]

Synonym: TTHA0974

Alternate gene names: 55980943

Gene position: 918432-917491 (Counterclockwise)

Preceding gene: 55980944

Following gene: 55980942

Centisome position: 49.65

GC content: 70.59

Gene sequence:

>942_bases
ATGTATAATGCCCCCATGCCGGAAGGCCCCGCAGCCCACGTGATCTGGAAAACCATCGGCCTCAAACGGCCCGAGAAGGC
CCTTTGGCCCCTCGCCCCCTACGCCGAGTACCTCCTCCTGGAGCGGGGCTACTCCCCAAGGGGGGTGCGCCGCTACCTCC
AGGACCTCGCCTTCTGGTTCCGCTTCCTCGAGGCGGAGGGCCTCTCCCCAAGCCCCGAGGCGGTGCGGGCCCTTCTCCTT
AGGGAGCGCTGGGCCCCAAGGCGCGTCCAGGGGTTCCTGGCCGCCCTGAGGAGCTACTACCGCTACCTGCGGGAGGTGAA
GGGCGAGGCGGCCTCGGACCCCACGGAGGGGATCGGCCGGCCCAAGGCCGGGAGGCGGCTTCCCCTGCACCCGGGCCCCG
AGGAGCTCAAGCGCTTCCTCGAGGCCTTCCGCGAGGAGAAGGAGGCGGCCCTCCTCGAGGCCCTGGCCCGCTTCCTCTAC
GGCACGGGCCTCCGCATCTCCGAGGCCCTCTCCCTGAAGGGGCGGAACGTGGTCCTCGAGGGAGGAAGCCCCGTGGCGGT
GCGGGTGGTGGGCAAGGGGAACAAGGAAAGGCTCGTGCCGCTCTCCAAGACGGCCCGGGAGGTCCTGGAGGCCTTGGGAC
GGCCGCAGGGAAATGTGAACATATTCACTTTCTCGCAGGGGCGGCGCAAAGGCCACGTCCCCTCGGCCCGCTGGGTGGAG
GCCAAGTTCCGGGAGGCCGCCCTCAGGGCGGGCCTGGACCCCAGGCGCTTCACCCCCCACAAGCTCCGCCACGCCTACGC
CACCCTCCTCGTGGAGCGGGGCGTGGAGCTGGACGCGGTAAAGGACCTCCTGGGGCACGAGTCCATCGCCACCACCCAGA
TCTACCTCCACGCCTCCCGGGAGCGCCTTCGGGAGGCGGCCTCGAGGCTCCCCGAGCTCTGA

Upstream 100 bases:

>100_bases
GGGCCGGGTCCGCCTCTTCCACCCAAAGACGGGGAAGGCCCTCGCCTGAGGGCGGATTTTCCTCCGGCCCCCCTATCTTC
GCGAAAGGTACATTTCGCGC

Downstream 100 bases:

>100_bases
ACCCCGCCCCAAGCGGGCTTGGGCCGGCGTGGAGGTTCCGCCAGGGTGGCGGGGACACTTGACCCTTCGCCCAGGTTGTG
CGAAACTAACAAACGACCGT

Product: integrase/recombinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MYNAPMPEGPAAHVIWKTIGLKRPEKALWPLAPYAEYLLLERGYSPRGVRRYLQDLAFWFRFLEAEGLSPSPEAVRALLL
RERWAPRRVQGFLAALRSYYRYLREVKGEAASDPTEGIGRPKAGRRLPLHPGPEELKRFLEAFREEKEAALLEALARFLY
GTGLRISEALSLKGRNVVLEGGSPVAVRVVGKGNKERLVPLSKTAREVLEALGRPQGNVNIFTFSQGRRKGHVPSARWVE
AKFREAALRAGLDPRRFTPHKLRHAYATLLVERGVELDAVKDLLGHESIATTQIYLHASRERLREAASRLPEL

Sequences:

>Translated_313_residues
MYNAPMPEGPAAHVIWKTIGLKRPEKALWPLAPYAEYLLLERGYSPRGVRRYLQDLAFWFRFLEAEGLSPSPEAVRALLL
RERWAPRRVQGFLAALRSYYRYLREVKGEAASDPTEGIGRPKAGRRLPLHPGPEELKRFLEAFREEKEAALLEALARFLY
GTGLRISEALSLKGRNVVLEGGSPVAVRVVGKGNKERLVPLSKTAREVLEALGRPQGNVNIFTFSQGRRKGHVPSARWVE
AKFREAALRAGLDPRRFTPHKLRHAYATLLVERGVELDAVKDLLGHESIATTQIYLHASRERLREAASRLPEL
>Mature_313_residues
MYNAPMPEGPAAHVIWKTIGLKRPEKALWPLAPYAEYLLLERGYSPRGVRRYLQDLAFWFRFLEAEGLSPSPEAVRALLL
RERWAPRRVQGFLAALRSYYRYLREVKGEAASDPTEGIGRPKAGRRLPLHPGPEELKRFLEAFREEKEAALLEALARFLY
GTGLRISEALSLKGRNVVLEGGSPVAVRVVGKGNKERLVPLSKTAREVLEALGRPQGNVNIFTFSQGRRKGHVPSARWVE
AKFREAALRAGLDPRRFTPHKLRHAYATLLVERGVELDAVKDLLGHESIATTQIYLHASRERLREAASRLPEL

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=285, Percent_Identity=34.0350877192982, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790244, Length=283, Percent_Identity=32.5088339222615, Blast_Score=120, Evalue=8e-29,
Organism=Escherichia coli, GI1786748, Length=186, Percent_Identity=27.9569892473118, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35365; Mature: 35365

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYNAPMPEGPAAHVIWKTIGLKRPEKALWPLAPYAEYLLLERGYSPRGVRRYLQDLAFWF
CCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RFLEAEGLSPSPEAVRALLLRERWAPRRVQGFLAALRSYYRYLREVKGEAASDPTEGIGR
HHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
PKAGRRLPLHPGPEELKRFLEAFREEKEAALLEALARFLYGTGLRISEALSLKGRNVVLE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEE
GGSPVAVRVVGKGNKERLVPLSKTAREVLEALGRPQGNVNIFTFSQGRRKGHVPSARWVE
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHH
AKFREAALRAGLDPRRFTPHKLRHAYATLLVERGVELDAVKDLLGHESIATTQIYLHASR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHEEHHHH
ERLREAASRLPEL
HHHHHHHHHCCCC
>Mature Secondary Structure
MYNAPMPEGPAAHVIWKTIGLKRPEKALWPLAPYAEYLLLERGYSPRGVRRYLQDLAFWF
CCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RFLEAEGLSPSPEAVRALLLRERWAPRRVQGFLAALRSYYRYLREVKGEAASDPTEGIGR
HHHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCC
PKAGRRLPLHPGPEELKRFLEAFREEKEAALLEALARFLYGTGLRISEALSLKGRNVVLE
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEEE
GGSPVAVRVVGKGNKERLVPLSKTAREVLEALGRPQGNVNIFTFSQGRRKGHVPSARWVE
CCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHH
AKFREAALRAGLDPRRFTPHKLRHAYATLLVERGVELDAVKDLLGHESIATTQIYLHASR
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHEEHHHH
ERLREAASRLPEL
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]