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The map label for this gene is rsmB [H]

Identifier: 55980820

GI number: 55980820

Start: 813740

End: 814936

Strand: Direct

Name: rsmB [H]

Synonym: TTHA0851

Alternate gene names: 55980820

Gene position: 813740-814936 (Clockwise)

Preceding gene: 55980819

Following gene: 55980821

Centisome position: 43.99

GC content: 73.27

Gene sequence:

>1197_bases
TTGAGGGCCGGGACGCCTCGAGCCCTGGCGGTGGCCGTCCTCCTCGAGGTGGATCGGGGAGGGCGGGCCCAGCTTCTCCT
GGACCGCGCCCTGAGGCGGTCCCCCTGGCCCGAGCGGGACCGGGCCTACGCCACCTTCCTGGTCTACGGGGCCCTCCGCC
GCCTCCGCCTTCTGGACCACCTCCTCGCCCCCCTCTTGCCCCGGCCCGAGGGCCTGCCCCCCGAGGTGCGCTGGATCCTC
CGCCTGGGGGCCCTGGAGTGGCTTGAGGGCAAGCCGGACCACGCCCGGGTGAGCCCCTGGGTGGAGGAGGCGAAGCGCCG
CTACCCGGGCCTCGCCGGGCTGGTGAACGCCGTTTTGCGGCGTCTTGCCCCTAGGGAGGCCCCGGAGTGCGTGCGCCTTT
CCCTCCCCGACTGGCTCTGCGAGGCCTGGCGGGGCTTCTTCGGGGACGTGGCCTTCGCCGAGGGCTTCAACGAGCCCGCC
CCCCTCTTCGTCACCGCCTACCGGGAGGTGGACCTAAGGCCCGGCCCCGTCCCCGGGAGCTACCTTTGGGAAGGCCCCAA
GACCGACTTTTCCGCCCTCGGCCTCCAGCCGCAAAACCCCGCCTCCCTCTTCGCGGCCAAGCTCCTCGAGGCCCGCCCTG
GGGAGCGGGTGCTGGACCTCTGCGGCGGGGCCGGGCTCAAGGCCTTCTACCTCGCCGCCCAGGGGGCGGAGGTGGTCTCC
TACGACCTAAACCGCAGGCGGCAGGAGGCGGGGGCGAGGACGGCGCGGCGGCTTGGCCTTTGGGTCCACTACCGCACCCA
GGACCTGACCCGGCCCGTGCCCGAGCGGGCGAAGAAGGTCCTCCTGGACGCCCCCTGCACCGGGACCGGCACCTTCCGCG
CCCACCCCGAGCTCCGCTACCGCCTAAGCCCCGAGGACCCTGCCCGCATGGCCGCCCTCCAGCTCCAGCTCCTGGAGACG
GCGGCCCAGGCCACGGAGGAAGGGGGGGTTCTCGTCTACAGCGTCTGCACCCTGACGGAGGAGGAGGGGGAAGGGGTGGT
GCGGGCCTTCCTGGCGCGCCACCCTGAGTTCCGCCCCGAGCCCGTCCAACCCCCCTTCCCCGTCCTCGCCCGGGGGCTTG
GGGTCTACGTGGACCCGAGGGGAGGGCTGGACGGCTTCTACTACGCCAAGCTGCGGAGGGTAAACTCTCAGGCATGA

Upstream 100 bases:

>100_bases
ACCTGGACCTGGTGGTGAAGCCCGCCTTCGTCAAGCTGGAGCTGGAGAACGAGGAGCGGACCGCCCTGAAGTTCAGCATC
AAGGCCCACCCCCTGGAAAC

Downstream 100 bases:

>100_bases
GGCTGGCCTTCGTGGGTCTCGGCAAGATGGGCCGGAGCATCCTCAAGGGGGCTCTGGAGCGGGGCTTCTTGCGCCCGGAG
GAGGTGGGGGTCTTGGGGCG

Product: RNA methyltransferase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRAGTPRALAVAVLLEVDRGGRAQLLLDRALRRSPWPERDRAYATFLVYGALRRLRLLDHLLAPLLPRPEGLPPEVRWIL
RLGALEWLEGKPDHARVSPWVEEAKRRYPGLAGLVNAVLRRLAPREAPECVRLSLPDWLCEAWRGFFGDVAFAEGFNEPA
PLFVTAYREVDLRPGPVPGSYLWEGPKTDFSALGLQPQNPASLFAAKLLEARPGERVLDLCGGAGLKAFYLAAQGAEVVS
YDLNRRRQEAGARTARRLGLWVHYRTQDLTRPVPERAKKVLLDAPCTGTGTFRAHPELRYRLSPEDPARMAALQLQLLET
AAQATEEGGVLVYSVCTLTEEEGEGVVRAFLARHPEFRPEPVQPPFPVLARGLGVYVDPRGGLDGFYYAKLRRVNSQA

Sequences:

>Translated_398_residues
MRAGTPRALAVAVLLEVDRGGRAQLLLDRALRRSPWPERDRAYATFLVYGALRRLRLLDHLLAPLLPRPEGLPPEVRWIL
RLGALEWLEGKPDHARVSPWVEEAKRRYPGLAGLVNAVLRRLAPREAPECVRLSLPDWLCEAWRGFFGDVAFAEGFNEPA
PLFVTAYREVDLRPGPVPGSYLWEGPKTDFSALGLQPQNPASLFAAKLLEARPGERVLDLCGGAGLKAFYLAAQGAEVVS
YDLNRRRQEAGARTARRLGLWVHYRTQDLTRPVPERAKKVLLDAPCTGTGTFRAHPELRYRLSPEDPARMAALQLQLLET
AAQATEEGGVLVYSVCTLTEEEGEGVVRAFLARHPEFRPEPVQPPFPVLARGLGVYVDPRGGLDGFYYAKLRRVNSQA
>Mature_398_residues
MRAGTPRALAVAVLLEVDRGGRAQLLLDRALRRSPWPERDRAYATFLVYGALRRLRLLDHLLAPLLPRPEGLPPEVRWIL
RLGALEWLEGKPDHARVSPWVEEAKRRYPGLAGLVNAVLRRLAPREAPECVRLSLPDWLCEAWRGFFGDVAFAEGFNEPA
PLFVTAYREVDLRPGPVPGSYLWEGPKTDFSALGLQPQNPASLFAAKLLEARPGERVLDLCGGAGLKAFYLAAQGAEVVS
YDLNRRRQEAGARTARRLGLWVHYRTQDLTRPVPERAKKVLLDAPCTGTGTFRAHPELRYRLSPEDPARMAALQLQLLET
AAQATEEGGVLVYSVCTLTEEEGEGVVRAFLARHPEFRPEPVQPPFPVLARGLGVYVDPRGGLDGFYYAKLRRVNSQA

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=187, Percent_Identity=33.1550802139037, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI76150625, Length=186, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI76150623, Length=186, Percent_Identity=30.1075268817204, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI11545785, Length=181, Percent_Identity=30.939226519337, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI2367212, Length=401, Percent_Identity=26.4339152119701, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI87081985, Length=206, Percent_Identity=29.6116504854369, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17536757, Length=250, Percent_Identity=27.2, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324268, Length=224, Percent_Identity=25.8928571428571, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI22024126, Length=267, Percent_Identity=28.4644194756554, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24668781, Length=188, Percent_Identity=29.2553191489362, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355201, Length=185, Percent_Identity=25.9459459459459, Blast_Score=69, Evalue=7e-12,
Organism=Drosophila melanogaster, GI21356513, Length=194, Percent_Identity=28.8659793814433, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 44313; Mature: 44313

Theoretical pI: Translated: 9.43; Mature: 9.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGTPRALAVAVLLEVDRGGRAQLLLDRALRRSPWPERDRAYATFLVYGALRRLRLLDH
CCCCCCHHHHEEHHEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLAPLLPRPEGLPPEVRWILRLGALEWLEGKPDHARVSPWVEEAKRRYPGLAGLVNAVLR
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
RLAPREAPECVRLSLPDWLCEAWRGFFGDVAFAEGFNEPAPLFVTAYREVDLRPGPVPGS
HHCCCCCCCCEEECCCHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC
YLWEGPKTDFSALGLQPQNPASLFAAKLLEARPGERVLDLCGGAGLKAFYLAAQGAEVVS
CCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHEEECCCCHHHH
YDLNRRRQEAGARTARRLGLWVHYRTQDLTRPVPERAKKVLLDAPCTGTGTFRAHPELRY
HHHHHHHHHHHHHHHHHHHEEEEECCHHHCCCHHHHHHHHEEECCCCCCCCEEECCCEEE
RLSPEDPARMAALQLQLLETAAQATEEGGVLVYSVCTLTEEEGEGVVRAFLARHPEFRPE
EECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCC
PVQPPFPVLARGLGVYVDPRGGLDGFYYAKLRRVNSQA
CCCCCHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MRAGTPRALAVAVLLEVDRGGRAQLLLDRALRRSPWPERDRAYATFLVYGALRRLRLLDH
CCCCCCHHHHEEHHEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LLAPLLPRPEGLPPEVRWILRLGALEWLEGKPDHARVSPWVEEAKRRYPGLAGLVNAVLR
HHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
RLAPREAPECVRLSLPDWLCEAWRGFFGDVAFAEGFNEPAPLFVTAYREVDLRPGPVPGS
HHCCCCCCCCEEECCCHHHHHHHHHHHCCHHHHCCCCCCCCEEEEEEEECCCCCCCCCCC
YLWEGPKTDFSALGLQPQNPASLFAAKLLEARPGERVLDLCGGAGLKAFYLAAQGAEVVS
CCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHEEECCCCHHHH
YDLNRRRQEAGARTARRLGLWVHYRTQDLTRPVPERAKKVLLDAPCTGTGTFRAHPELRY
HHHHHHHHHHHHHHHHHHHEEEEECCHHHCCCHHHHHHHHEEECCCCCCCCEEECCCEEE
RLSPEDPARMAALQLQLLETAAQATEEGGVLVYSVCTLTEEEGEGVVRAFLARHPEFRPE
EECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCCCCC
PVQPPFPVLARGLGVYVDPRGGLDGFYYAKLRRVNSQA
CCCCCHHHHHCCCCEEECCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]