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The map label for this gene is resA [H]

Identifier: 55980809

GI number: 55980809

Start: 804892

End: 805683

Strand: Direct

Name: resA [H]

Synonym: TTHA0840

Alternate gene names: 55980809

Gene position: 804892-805683 (Clockwise)

Preceding gene: 55980808

Following gene: 55980817

Centisome position: 43.51

GC content: 68.18

Gene sequence:

>792_bases
ATGGACGCCCTTCAGGTGGGCCCCTTGGCCATCCCCTGGGTGAGGGTGCAGGTGGCCTTGGCCCTCCTCGCCCTGGTGGG
GGTGGCGGAGCTTTTTGCCCGCCGGGTGGACCGGAGGCTTTCCTCCTGGGGCCAGGGCGCCGTTTTTGTGGGCCTTCTGG
GGGCCAGGCTTGGCTTTGTCTTGGAGAACGCGTCGGTTTACGCCAAGGACCCCCTCGCCGTTCTCTACGTCTGGCAGGGG
GGGTTTGACCCCTGGTGGGGTATCTTGGCTGGAGGAGGGTATACGCTCATGGCCTTGCCCAAACACCTCTGGCGCTACGC
CCTGGGGGCGGCCCTGGCCGCGGCCCTGGTGGCGGGGGTCTTCCTCGTCCGCAAGGCCCCGGCCCAGGAGGCGCGCCTCC
CCGACCTAACCCTCACGACCCTTGGGGGGACGGAGGTACGCCTCAGCGATTTCCGGGGGAAGCCCCTGGTCCTCAACGCC
TGGGCCACCTGGTGCCCCCCCTGCCGCCGGGAGCTCCCCATGATGGTGCGCCTCGCTCAGGAGAACCCGGAGGTGCGCTT
CGCCTTTGTAAGCCAGGGGGAAGGCCCCCTGGTGGTGAAAAACTTTTTGGAGGAAAGGGGCCTTTCTCCCGAGTGGGTTC
TTCTGGACCCCGAGACCCGGCTTGCCCAGGCCTTGGGCATCCAGGGGCTTCCCACCACCTTCTTCTTTGACCGGGAGGGG
CGGCTCGTGGCCCGGCACCTGGGGGAGCTTTCCGAGGCCCTGCTTTTGGGCTACCTCCGGGTCCTCCGCTAG

Upstream 100 bases:

>100_bases
AGGCGGCGGAGTACCTGGCGCGGAAGGGCTACACGAACCTCTACAACGTGGAGGGCGGGGTGCTGGCCATAGCGCGGGCG
GGGTATCCCCTGGTCCGGTG

Downstream 100 bases:

>100_bases
GCGCCGGCGGAAAGGAGGGTTTCCTTCCCGCCCACCACCGTTTTGAGGTGGACGGGCCTGCCCCAGAGGCGGTGGAGGTT
CTCCAGCACCGCCTTGGTCT

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MDALQVGPLAIPWVRVQVALALLALVGVAELFARRVDRRLSSWGQGAVFVGLLGARLGFVLENASVYAKDPLAVLYVWQG
GFDPWWGILAGGGYTLMALPKHLWRYALGAALAAALVAGVFLVRKAPAQEARLPDLTLTTLGGTEVRLSDFRGKPLVLNA
WATWCPPCRRELPMMVRLAQENPEVRFAFVSQGEGPLVVKNFLEERGLSPEWVLLDPETRLAQALGIQGLPTTFFFDREG
RLVARHLGELSEALLLGYLRVLR

Sequences:

>Translated_263_residues
MDALQVGPLAIPWVRVQVALALLALVGVAELFARRVDRRLSSWGQGAVFVGLLGARLGFVLENASVYAKDPLAVLYVWQG
GFDPWWGILAGGGYTLMALPKHLWRYALGAALAAALVAGVFLVRKAPAQEARLPDLTLTTLGGTEVRLSDFRGKPLVLNA
WATWCPPCRRELPMMVRLAQENPEVRFAFVSQGEGPLVVKNFLEERGLSPEWVLLDPETRLAQALGIQGLPTTFFFDREG
RLVARHLGELSEALLLGYLRVLR
>Mature_263_residues
MDALQVGPLAIPWVRVQVALALLALVGVAELFARRVDRRLSSWGQGAVFVGLLGARLGFVLENASVYAKDPLAVLYVWQG
GFDPWWGILAGGGYTLMALPKHLWRYALGAALAAALVAGVFLVRKAPAQEARLPDLTLTTLGGTEVRLSDFRGKPLVLNA
WATWCPPCRRELPMMVRLAQENPEVRFAFVSQGEGPLVVKNFLEERGLSPEWVLLDPETRLAQALGIQGLPTTFFFDREG
RLVARHLGELSEALLLGYLRVLR

Specific function: Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c; following this reduction heme can be covalent

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein. Note=The thioredoxin-like motif is exposed on the outside of the membrane (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=100, Percent_Identity=34, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: NA

Molecular weight: Translated: 28892; Mature: 28892

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDALQVGPLAIPWVRVQVALALLALVGVAELFARRVDRRLSSWGQGAVFVGLLGARLGFV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LENASVYAKDPLAVLYVWQGGFDPWWGILAGGGYTLMALPKHLWRYALGAALAAALVAGV
EECCEEEECCCEEEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVRKAPAQEARLPDLTLTTLGGTEVRLSDFRGKPLVLNAWATWCPPCRRELPMMVRLAQ
HHHHCCCHHHCCCCCEEEEECCCCEEEEECCCCCCEEEECCHHCCCHHHHCCHHHHHHHC
ENPEVRFAFVSQGEGPLVVKNFLEERGLSPEWVLLDPETRLAQALGIQGLPTTFFFDREG
CCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCEEEECCCC
RLVARHLGELSEALLLGYLRVLR
CHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MDALQVGPLAIPWVRVQVALALLALVGVAELFARRVDRRLSSWGQGAVFVGLLGARLGFV
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
LENASVYAKDPLAVLYVWQGGFDPWWGILAGGGYTLMALPKHLWRYALGAALAAALVAGV
EECCEEEECCCEEEEEEEECCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FLVRKAPAQEARLPDLTLTTLGGTEVRLSDFRGKPLVLNAWATWCPPCRRELPMMVRLAQ
HHHHCCCHHHCCCCCEEEEECCCCEEEEECCCCCCEEEECCHHCCCHHHHCCHHHHHHHC
ENPEVRFAFVSQGEGPLVVKNFLEERGLSPEWVLLDPETRLAQALGIQGLPTTFFFDREG
CCCCEEEEEEECCCCCHHHHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCEEEECCCC
RLVARHLGELSEALLLGYLRVLR
CHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA