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The map label for this gene is estB [H]

Identifier: 55980721

GI number: 55980721

Start: 718549

End: 719715

Strand: Direct

Name: estB [H]

Synonym: TTHA0752

Alternate gene names: 55980721

Gene position: 718549-719715 (Clockwise)

Preceding gene: 55980720

Following gene: 55980724

Centisome position: 38.85

GC content: 70.87

Gene sequence:

>1167_bases
ATGAACCTAAGGAGGCTTGACGCCTACTTCCGGCGCCTGGTGGAGGAGGGCCTCCTCCCCGGGGCCGTGGTCCTCGTGGC
CCGGGGTGGGGAGGTGGTCTTCCAGGGGGTCTACGGGTACCTGGACCCGGGGCGGGGGCTTCCCATGCGGGAGGACGCCC
TCTTCCGCCTCTACTCCATGACCAAGCCCTGGGTCTCCGCCCTGGCCCTGAGCTTCGTGGAGGAGGGGACCCTCTCCCTC
CTGGACCCCGTGGAGAAGTACCTGCCGGAGTTTTCCGGGCTCCGGGTGGGGCGGGAGGTGGGGGAGGGGATCGTCTACGA
GCCCCTGAAGCGCCCCCTCACCGTCTACGACCTCCTCCGCCACACCGCGGGGCTCACCTACGGGGTCTTCTTCCGCTCCC
CGGTGAAGGGGCTTTACCTCGAGGCCGGGGTGGACCGGTTTGACCTGAGCCGGGAGGTCTTTTTGGAGCGCCTCGCCGCG
CTGCCTTTGCGCTTCCAGCCCGGGGAGACCTTTGAGTACGGCCTCGCCACCGACCTCCTCGGCCACCTCCTGGAGGCTTT
GGCGGGGCGGAGCCTGGCGGAGCTTTTGGAGGAACGGCTTTTCCGCCCCCTGGGCATGAGGGACTCGGGCTTCCAGGCCA
AGGACCCCGCCCGGCTGGCCCAGCCCTTCCCCAAGGACCCGGAGACGGGCCATAGCCTCCGCCTCCTCCCGGTGGAAACC
CCCCCGCCCCGGTACGCCGGGGGGATGGGGGGCGTGGGCACCGCGGCGGACTACCTCGCCTTCCTCGAGGCCCTTCGCCT
GGGGCGGGGCGCGCTTTCCCCCACCATGGCGGGTTTCATGGTCCAGGACCACCTGGGAAGCCTCTACCCCGAGGCCCTCA
AGCGGGGGCCCGAGTACCTCCCCGGGCCCGGGTACAGCTTCGGCCTCGGGGTGGCGGTGCGGGTGGAGCCCATGGGCTAC
TCCCCGGGCGCCTTAGGGGAGTGGACCTGGGCGGGCTTCGGCGGGACCTTCTTCTTCGTGGACCCCCTCCAGGAGATCAC
CGCCCTCTACCTCGCCCAGGCCCCGAACCTCCTCTCCGTCCTGGAGCCGGAGAAGGCCCTCCACTCCCGGCTTGGGGCCA
GGCTCCAGCACGCCTTCCGCACCCTGGTCTACCTGGGCCTGGAGTGA

Upstream 100 bases:

>100_bases
TTTTGGGCTTCTTCGTGAAGTGGCTTCTGCCCTTGGCGCTTCTCCTCCTCGCCCTCTGGCTCCTCCTGAGCCCGAAGAGG
CCCGTTCCTGAGGGGTGGTG

Downstream 100 bases:

>100_bases
AGGAGGTCTTGGACCCTCTCCAGGGCAAGGGGGATGTCCTCGTCCATGAGGTCCCGGTGGGTCACGAACCGCACCCTTCC
CCCCACGCGCCCCGCGAGCA

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLRRLDAYFRRLVEEGLLPGAVVLVARGGEVVFQGVYGYLDPGRGLPMREDALFRLYSMTKPWVSALALSFVEEGTLSL
LDPVEKYLPEFSGLRVGREVGEGIVYEPLKRPLTVYDLLRHTAGLTYGVFFRSPVKGLYLEAGVDRFDLSREVFLERLAA
LPLRFQPGETFEYGLATDLLGHLLEALAGRSLAELLEERLFRPLGMRDSGFQAKDPARLAQPFPKDPETGHSLRLLPVET
PPPRYAGGMGGVGTAADYLAFLEALRLGRGALSPTMAGFMVQDHLGSLYPEALKRGPEYLPGPGYSFGLGVAVRVEPMGY
SPGALGEWTWAGFGGTFFFVDPLQEITALYLAQAPNLLSVLEPEKALHSRLGARLQHAFRTLVYLGLE

Sequences:

>Translated_388_residues
MNLRRLDAYFRRLVEEGLLPGAVVLVARGGEVVFQGVYGYLDPGRGLPMREDALFRLYSMTKPWVSALALSFVEEGTLSL
LDPVEKYLPEFSGLRVGREVGEGIVYEPLKRPLTVYDLLRHTAGLTYGVFFRSPVKGLYLEAGVDRFDLSREVFLERLAA
LPLRFQPGETFEYGLATDLLGHLLEALAGRSLAELLEERLFRPLGMRDSGFQAKDPARLAQPFPKDPETGHSLRLLPVET
PPPRYAGGMGGVGTAADYLAFLEALRLGRGALSPTMAGFMVQDHLGSLYPEALKRGPEYLPGPGYSFGLGVAVRVEPMGY
SPGALGEWTWAGFGGTFFFVDPLQEITALYLAQAPNLLSVLEPEKALHSRLGARLQHAFRTLVYLGLE
>Mature_388_residues
MNLRRLDAYFRRLVEEGLLPGAVVLVARGGEVVFQGVYGYLDPGRGLPMREDALFRLYSMTKPWVSALALSFVEEGTLSL
LDPVEKYLPEFSGLRVGREVGEGIVYEPLKRPLTVYDLLRHTAGLTYGVFFRSPVKGLYLEAGVDRFDLSREVFLERLAA
LPLRFQPGETFEYGLATDLLGHLLEALAGRSLAELLEERLFRPLGMRDSGFQAKDPARLAQPFPKDPETGHSLRLLPVET
PPPRYAGGMGGVGTAADYLAFLEALRLGRGALSPTMAGFMVQDHLGSLYPEALKRGPEYLPGPGYSFGLGVAVRVEPMGY
SPGALGEWTWAGFGGTFFFVDPLQEITALYLAQAPNLLSVLEPEKALHSRLGARLQHAFRTLVYLGLE

Specific function: Acts on short-chain (C4-C6) fatty acid esters and triglycerides, including tertiary alcohol esters. Activity on p- nitrophenyl esters is generally higher than on o-nitrophenyl esters. Lacks beta-lactamase activity; it hydrolyzes the ester bond of cephalos

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17550934, Length=254, Percent_Identity=24.4094488188976, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 42708; Mature: 42708

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRRLDAYFRRLVEEGLLPGAVVLVARGGEVVFQGVYGYLDPGRGLPMREDALFRLYSM
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHCCCCCCCCCCCHHHHHHHHHH
TKPWVSALALSFVEEGTLSLLDPVEKYLPEFSGLRVGREVGEGIVYEPLKRPLTVYDLLR
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHCCCCCHHHHHCCHHHHHHHH
HTAGLTYGVFFRSPVKGLYLEAGVDRFDLSREVFLERLAALPLRFQPGETFEYGLATDLL
HHCCCEEEHHHHCCCCHHHHHCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
GHLLEALAGRSLAELLEERLFRPLGMRDSGFQAKDPARLAQPFPKDPETGHSLRLLPVET
HHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCC
PPPRYAGGMGGVGTAADYLAFLEALRLGRGALSPTMAGFMVQDHLGSLYPEALKRGPEYL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCC
PGPGYSFGLGVAVRVEPMGYSPGALGEWTWAGFGGTFFFVDPLQEITALYLAQAPNLLSV
CCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHCCCCHHHH
LEPEKALHSRLGARLQHAFRTLVYLGLE
CCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLRRLDAYFRRLVEEGLLPGAVVLVARGGEVVFQGVYGYLDPGRGLPMREDALFRLYSM
CCHHHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEHHHHCCCCCCCCCCCHHHHHHHHHH
TKPWVSALALSFVEEGTLSLLDPVEKYLPEFSGLRVGREVGEGIVYEPLKRPLTVYDLLR
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHCCHHHHHHCCCCCHHHHHCCHHHHHHHH
HTAGLTYGVFFRSPVKGLYLEAGVDRFDLSREVFLERLAALPLRFQPGETFEYGLATDLL
HHCCCEEEHHHHCCCCHHHHHCCCCHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHH
GHLLEALAGRSLAELLEERLFRPLGMRDSGFQAKDPARLAQPFPKDPETGHSLRLLPVET
HHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCEEEEECCC
PPPRYAGGMGGVGTAADYLAFLEALRLGRGALSPTMAGFMVQDHLGSLYPEALKRGPEYL
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCC
PGPGYSFGLGVAVRVEPMGYSPGALGEWTWAGFGGTFFFVDPLQEITALYLAQAPNLLSV
CCCCCCCCCEEEEEEEECCCCCCCCCCCEEECCCCEEEEECHHHHHHHHHHHCCCCHHHH
LEPEKALHSRLGARLQHAFRTLVYLGLE
CCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11472796; 11847270 [H]