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The map label for this gene is secD [H]

Identifier: 55980666

GI number: 55980666

Start: 659783

End: 661990

Strand: Reverse

Name: secD [H]

Synonym: TTHA0697

Alternate gene names: 55980666

Gene position: 661990-659783 (Counterclockwise)

Preceding gene: 55980667

Following gene: 55980664

Centisome position: 35.79

GC content: 68.16

Gene sequence:

>2208_bases
ATGAACCGGAAAAACCTCACCAGCCTGTTCCTGCTCGGCGTGTTTCTTCTCGCCCTCCTCTTCGTATGGAAGCCCTGGGC
CCCCGAGGAGCCCAAGGTCCGCCTGGGCCTGGACCTGAAGGGGGGTCTGAGGATCGTCCTCGAGGCCGACGTGGAGAACC
CCACCCTGGACGACCTGGAGAAGGCCAGGACCGTCCTGGAGAACCGGATCAACGCCCTCGGCGTGGCCGAGCCCCTCATC
CAGATCCAGGGGCAGAAGCGGATCGTGGTGGAGCTCCCCGGCCTCTCCCAGGCCGACCAGGACCGCGCCCTCAAGCTCAT
TGGGCAGAGGGCGGTCCTGGAGTTCCGCATCGTCAAGGAGGGGGCCACGGGCACCACCGTGGCCCAGATCAACCAGGCCC
TCCGGGAGAACCCCAGGCTCAACCGGGAGGAGCTGGAGAAGGACCTGATCAAGCCGGAGGACCTCGGCCCGCCCCTCCTC
ACCGGGGCGGACCTGGCCGACGCCCGGGCGGTCTTTGACCAGTTCGGCCGTCCCCAGGTCTCCCTCACCTTCACCCCGGA
AGGGGCGAAGAAGTTTGAGGAGGTCACCCGGCAGAACATCGGCAAGCGGCTCGCCATCGTCCTGGACGGCCGGGTCTACA
CCGCCCCCGTGATCCGCCAGGCCATCACCGGAGGCCAGGCGGTCATAGAGGGGCTTTCCAGCGTGGAGGAGGCGAGCGAG
ATCGCCCTCGTCCTGCGCTCGGGCTCCCTGCCGGTCCCCCTCAAGGTGGCGGAGATCCGGGCCATCGGCCCCACCCTGGG
CCAGGACGCCATCCAGGCGGGGATCCGCTCCGCCCTCATCGGCACCCTGGCCATCTTCCTCCTCATCTTCGCCTACTACG
GCCCCCACCTGGGGCTCGTGGCCTCCTTGGGCCTCCTCTACACCTCGGCCCTCATCCTGGGCCTCCTCTCGGGCCTCGGG
GCCACCCTGACCCTCCCCGGCATCGCCGGCCTCGTCCTCACCCTGGGGGCGGCGGTGGACGGCAACGTCCTCTCCTTTGA
GCGCATCAAGGAGGAGCTCAGGGCCGGGAAGAAGCTCCGCCAGGCCATCCCCGAGGGCTTCCGCCACTCCACCCTCACCA
TCATGGACGTGAACATCGCCCACCTCCTGGCGGCGGCCGCCCTCTACCAGTACGCCACCGGGCCGGTGCGGGGCTTCGCC
GTGATCCTGGCCATCGGCGTGGTGGCCAGCGTCTTCTCCAACCTCGTCTTCAGCCGCCACCTCCTGGAGCGCCTGGCCGA
CCGGGGCGAGATCCGCCCCCCCATGTGGCTCGTGGACCCGCGGTTCAACTTCATGGGCCCCGCCCGCTACGTCACGGCGG
CCACCCTCCTCCTCGCCGCTTTGGCGGCGGGCGTGGTCTTCGCCAAGGGCTTCAACTACTCCATTGACTTCACCGGGGGG
ACAGCCTACACCCTGCGGGCCGAGCCCAACGTGGAGGTGGAGACGCTGAGGCGTTTCCTCGAGGAGAAGGGCTTCCCCGG
CAAGGAGGCGGTGATCACCCAGGTCCAGGCCCCCACGGCGGCCTACCGGGAGTTTCTGGTGAAGCTCCCGCCCCTTTCCG
ACGAGAGGCGGCTTGAGCTGGAACGGCTTTTCGCCTCCGAGCTCAAGGCCACGGTCCTGGCCTCGGAGACCGTGGGGCCG
GCCATCGGGGAGGAGCTGAGGCGCAACGCGGTGATGGCGGTCCTGGTGGGGCTTGGCCTCATCCTCCTCTACGTGGCCTT
CCGCTTTGACTGGACCTTCGGCGTGGCCAGCATCCTGGCCGTGGCCCACGACGTGGCCATCGTGGCCGGGATGTACAGCC
TCCTGGGCCTGGAGTTCTCCATCCCCACCATCGCCGCCCTCCTCACCATCGTGGGCTACTCCATCAACGACTCCATCGTG
GTCTCGGACCGCATCCGGGAGAACCAGAAGCTCCTCCGGCACCTGCCCTACGCCGAGCTCGTCAACCGCTCCATCAACCA
GACCCTCTCCCGCACGGTGATGACGAGCCTCACCACCCTCCTTCCCATCCTCGCCCTCCTCTTCCTGGGAGGGAGCGTCC
TCAGGGACTTCGCCCTGGCCATCTTCGTGGGCATCTTCGTGGGAACCTACAGCTCCATCTACGTGGTGAGCGCCTTGGTG
GTGGCCTGGAAAAACCGCAGGAAGGCCCAAGAGGCCAGCAAGGCCTAG

Upstream 100 bases:

>100_bases
GGAAGGGGGTTAGGCGCCTCTCCCCGCGGAACGTCTTGCGGCAAAGGCGGCAAAAGGCATTAGGGACCACGGCGCGTGAC
GCGCACCCAAGGGGAAGCGC

Downstream 100 bases:

>100_bases
TCCCCTTCCAGCTCCGCCTCCGCCACAAGGCGGAGGCGGAGCCCTTTTTCGTAGAGCGCCGTCCCCCGGAGGCGGCCCAA
AGCCGCCTCGTCCAGGGGGT

Product: bifunctional preprotein translocase subunit SecD/SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 735; Mature: 735

Protein sequence:

>735_residues
MNRKNLTSLFLLGVFLLALLFVWKPWAPEEPKVRLGLDLKGGLRIVLEADVENPTLDDLEKARTVLENRINALGVAEPLI
QIQGQKRIVVELPGLSQADQDRALKLIGQRAVLEFRIVKEGATGTTVAQINQALRENPRLNREELEKDLIKPEDLGPPLL
TGADLADARAVFDQFGRPQVSLTFTPEGAKKFEEVTRQNIGKRLAIVLDGRVYTAPVIRQAITGGQAVIEGLSSVEEASE
IALVLRSGSLPVPLKVAEIRAIGPTLGQDAIQAGIRSALIGTLAIFLLIFAYYGPHLGLVASLGLLYTSALILGLLSGLG
ATLTLPGIAGLVLTLGAAVDGNVLSFERIKEELRAGKKLRQAIPEGFRHSTLTIMDVNIAHLLAAAALYQYATGPVRGFA
VILAIGVVASVFSNLVFSRHLLERLADRGEIRPPMWLVDPRFNFMGPARYVTAATLLLAALAAGVVFAKGFNYSIDFTGG
TAYTLRAEPNVEVETLRRFLEEKGFPGKEAVITQVQAPTAAYREFLVKLPPLSDERRLELERLFASELKATVLASETVGP
AIGEELRRNAVMAVLVGLGLILLYVAFRFDWTFGVASILAVAHDVAIVAGMYSLLGLEFSIPTIAALLTIVGYSINDSIV
VSDRIRENQKLLRHLPYAELVNRSINQTLSRTVMTSLTTLLPILALLFLGGSVLRDFALAIFVGIFVGTYSSIYVVSALV
VAWKNRRKAQEASKA

Sequences:

>Translated_735_residues
MNRKNLTSLFLLGVFLLALLFVWKPWAPEEPKVRLGLDLKGGLRIVLEADVENPTLDDLEKARTVLENRINALGVAEPLI
QIQGQKRIVVELPGLSQADQDRALKLIGQRAVLEFRIVKEGATGTTVAQINQALRENPRLNREELEKDLIKPEDLGPPLL
TGADLADARAVFDQFGRPQVSLTFTPEGAKKFEEVTRQNIGKRLAIVLDGRVYTAPVIRQAITGGQAVIEGLSSVEEASE
IALVLRSGSLPVPLKVAEIRAIGPTLGQDAIQAGIRSALIGTLAIFLLIFAYYGPHLGLVASLGLLYTSALILGLLSGLG
ATLTLPGIAGLVLTLGAAVDGNVLSFERIKEELRAGKKLRQAIPEGFRHSTLTIMDVNIAHLLAAAALYQYATGPVRGFA
VILAIGVVASVFSNLVFSRHLLERLADRGEIRPPMWLVDPRFNFMGPARYVTAATLLLAALAAGVVFAKGFNYSIDFTGG
TAYTLRAEPNVEVETLRRFLEEKGFPGKEAVITQVQAPTAAYREFLVKLPPLSDERRLELERLFASELKATVLASETVGP
AIGEELRRNAVMAVLVGLGLILLYVAFRFDWTFGVASILAVAHDVAIVAGMYSLLGLEFSIPTIAALLTIVGYSINDSIV
VSDRIRENQKLLRHLPYAELVNRSINQTLSRTVMTSLTTLLPILALLFLGGSVLRDFALAIFVGIFVGTYSSIYVVSALV
VAWKNRRKAQEASKA
>Mature_735_residues
MNRKNLTSLFLLGVFLLALLFVWKPWAPEEPKVRLGLDLKGGLRIVLEADVENPTLDDLEKARTVLENRINALGVAEPLI
QIQGQKRIVVELPGLSQADQDRALKLIGQRAVLEFRIVKEGATGTTVAQINQALRENPRLNREELEKDLIKPEDLGPPLL
TGADLADARAVFDQFGRPQVSLTFTPEGAKKFEEVTRQNIGKRLAIVLDGRVYTAPVIRQAITGGQAVIEGLSSVEEASE
IALVLRSGSLPVPLKVAEIRAIGPTLGQDAIQAGIRSALIGTLAIFLLIFAYYGPHLGLVASLGLLYTSALILGLLSGLG
ATLTLPGIAGLVLTLGAAVDGNVLSFERIKEELRAGKKLRQAIPEGFRHSTLTIMDVNIAHLLAAAALYQYATGPVRGFA
VILAIGVVASVFSNLVFSRHLLERLADRGEIRPPMWLVDPRFNFMGPARYVTAATLLLAALAAGVVFAKGFNYSIDFTGG
TAYTLRAEPNVEVETLRRFLEEKGFPGKEAVITQVQAPTAAYREFLVKLPPLSDERRLELERLFASELKATVLASETVGP
AIGEELRRNAVMAVLVGLGLILLYVAFRFDWTFGVASILAVAHDVAIVAGMYSLLGLEFSIPTIAALLTIVGYSINDSIV
VSDRIRENQKLLRHLPYAELVNRSINQTLSRTVMTSLTTLLPILALLFLGGSVLRDFALAIFVGIFVGTYSSIYVVSALV
VAWKNRRKAQEASKA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=388, Percent_Identity=37.6288659793814, Blast_Score=227, Evalue=3e-60,
Organism=Escherichia coli, GI1786610, Length=297, Percent_Identity=38.047138047138, Blast_Score=188, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 79679; Mature: 79679

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKNLTSLFLLGVFLLALLFVWKPWAPEEPKVRLGLDLKGGLRIVLEADVENPTLDDLE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHH
KARTVLENRINALGVAEPLIQIQGQKRIVVELPGLSQADQDRALKLIGQRAVLEFRIVKE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEC
GATGTTVAQINQALRENPRLNREELEKDLIKPEDLGPPLLTGADLADARAVFDQFGRPQV
CCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
SLTFTPEGAKKFEEVTRQNIGKRLAIVLDGRVYTAPVIRQAITGGQAVIEGLSSVEEASE
EEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IALVLRSGSLPVPLKVAEIRAIGPTLGQDAIQAGIRSALIGTLAIFLLIFAYYGPHLGLV
HHHHEECCCCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ASLGLLYTSALILGLLSGLGATLTLPGIAGLVLTLGAAVDGNVLSFERIKEELRAGKKLR
HHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QAIPEGFRHSTLTIMDVNIAHLLAAAALYQYATGPVRGFAVILAIGVVASVFSNLVFSRH
HHCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLERLADRGEIRPPMWLVDPRFNFMGPARYVTAATLLLAALAAGVVFAKGFNYSIDFTGG
HHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
TAYTLRAEPNVEVETLRRFLEEKGFPGKEAVITQVQAPTAAYREFLVKLPPLSDERRLEL
EEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHH
ERLFASELKATVLASETVGPAIGEELRRNAVMAVLVGLGLILLYVAFRFDWTFGVASILA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHDVAIVAGMYSLLGLEFSIPTIAALLTIVGYSINDSIVVSDRIRENQKLLRHLPYAEL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCHHHH
VNRSINQTLSRTVMTSLTTLLPILALLFLGGSVLRDFALAIFVGIFVGTYSSIYVVSALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAWKNRRKAQEASKA
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRKNLTSLFLLGVFLLALLFVWKPWAPEEPKVRLGLDLKGGLRIVLEADVENPTLDDLE
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEEECCCCCCHHHHH
KARTVLENRINALGVAEPLIQIQGQKRIVVELPGLSQADQDRALKLIGQRAVLEFRIVKE
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHEEEEEEC
GATGTTVAQINQALRENPRLNREELEKDLIKPEDLGPPLLTGADLADARAVFDQFGRPQV
CCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEE
SLTFTPEGAKKFEEVTRQNIGKRLAIVLDGRVYTAPVIRQAITGGQAVIEGLSSVEEASE
EEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHH
IALVLRSGSLPVPLKVAEIRAIGPTLGQDAIQAGIRSALIGTLAIFLLIFAYYGPHLGLV
HHHHEECCCCCCCEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ASLGLLYTSALILGLLSGLGATLTLPGIAGLVLTLGAAVDGNVLSFERIKEELRAGKKLR
HHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QAIPEGFRHSTLTIMDVNIAHLLAAAALYQYATGPVRGFAVILAIGVVASVFSNLVFSRH
HHCCCCCCCCEEEEEECHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LLERLADRGEIRPPMWLVDPRFNFMGPARYVTAATLLLAALAAGVVFAKGFNYSIDFTGG
HHHHHHHCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
TAYTLRAEPNVEVETLRRFLEEKGFPGKEAVITQVQAPTAAYREFLVKLPPLSDERRLEL
EEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHH
ERLFASELKATVLASETVGPAIGEELRRNAVMAVLVGLGLILLYVAFRFDWTFGVASILA
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAHDVAIVAGMYSLLGLEFSIPTIAALLTIVGYSINDSIVVSDRIRENQKLLRHLPYAEL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHCCHHHH
VNRSINQTLSRTVMTSLTTLLPILALLFLGGSVLRDFALAIFVGIFVGTYSSIYVVSALV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAWKNRRKAQEASKA
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9826342 [H]