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The map label for this gene is livG [H]

Identifier: 55980664

GI number: 55980664

Start: 657419

End: 657835

Strand: Reverse

Name: livG [H]

Synonym: TTHA0695

Alternate gene names: 55980664

Gene position: 657835-657419 (Counterclockwise)

Preceding gene: 55980666

Following gene: 55980663

Centisome position: 35.56

GC content: 68.82

Gene sequence:

>417_bases
ATGGCGAGGAGGACGAGCCTCAGCCCCAAGGGCCAGCCCCGGACGAGGCTTAGCGCCCTTTCCACCTCAAAGGCGGGGAG
CTCCGGAGCCAGGGCCTTGGCCTCGGAGCTCACCCTCCTCGAGGACAAGCGTCTGGAGCTCGCCCGCGCCCTGGCCACGA
GGCCCAAGGTCCTCCTTTTGGACGAGGTCATGGCGGGGCTTCGGCCCAAGGAGGCCCAGGAGGCGGTGGAGATGATCCGG
AGGATCCGAAATAGCGGGGTCTCCATCCTCTTCATTGAGCACCTGATGCCCGTGGTCAAGGCCCTGGCCGACCGGGTGGT
GGTCCTGGACCACGGGGAGAAGATCGCCGAGGGCGCCTACGAGGAGGTGGCCCGGGAGGAGCGGGTGCGGGAGGCCTACC
TGGGGAGGCGGGCATGA

Upstream 100 bases:

>100_bases
GGAGGCCCGGTCCAGGACCTCCTTGGGCAGGGCCTGCCCCAGGTAGGCGAGAAGCCCCTCGGCGCTCTCCAGGGCGAGCT
CGGGCCTCAGGCCCTTGCGC

Downstream 100 bases:

>100_bases
GGCTGGAGGTCCAGGCCCTGGAAACCGGCTACGGCAAGGCCCAGGTCCTCTTCGGCGTGGACCTGGAGGTGGAAGCAGGG
GAGCTCGTGGCCCTCCTCGG

Product: amino acid ABC transporter ATP-binding protein

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein G [H]

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MARRTSLSPKGQPRTRLSALSTSKAGSSGARALASELTLLEDKRLELARALATRPKVLLLDEVMAGLRPKEAQEAVEMIR
RIRNSGVSILFIEHLMPVVKALADRVVVLDHGEKIAEGAYEEVAREERVREAYLGRRA

Sequences:

>Translated_138_residues
MARRTSLSPKGQPRTRLSALSTSKAGSSGARALASELTLLEDKRLELARALATRPKVLLLDEVMAGLRPKEAQEAVEMIR
RIRNSGVSILFIEHLMPVVKALADRVVVLDHGEKIAEGAYEEVAREERVREAYLGRRA
>Mature_137_residues
ARRTSLSPKGQPRTRLSALSTSKAGSSGARALASELTLLEDKRLELARALATRPKVLLLDEVMAGLRPKEAQEAVEMIRR
IRNSGVSILFIEHLMPVVKALADRVVVLDHGEKIAEGAYEEVAREERVREAYLGRRA

Specific function: Component of the leucine-specific transport system [H]

COG id: COG0411

COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1789864, Length=103, Percent_Identity=42.7184466019417, Blast_Score=87, Evalue=4e-19,
Organism=Escherichia coli, GI1789593, Length=104, Percent_Identity=34.6153846153846, Blast_Score=70, Evalue=5e-14,
Organism=Escherichia coli, GI1786398, Length=117, Percent_Identity=35.042735042735, Blast_Score=66, Evalue=8e-13,
Organism=Escherichia coli, GI1789672, Length=110, Percent_Identity=29.0909090909091, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=95, Percent_Identity=35.7894736842105, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 15242; Mature: 15111

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRTSLSPKGQPRTRLSALSTSKAGSSGARALASELTLLEDKRLELARALATRPKVLLL
CCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DEVMAGLRPKEAQEAVEMIRRIRNSGVSILFIEHLMPVVKALADRVVVLDHGEKIAEGAY
HHHHHCCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
EEVAREERVREAYLGRRA
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARRTSLSPKGQPRTRLSALSTSKAGSSGARALASELTLLEDKRLELARALATRPKVLLL
CCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
DEVMAGLRPKEAQEAVEMIRRIRNSGVSILFIEHLMPVVKALADRVVVLDHGEKIAEGAY
HHHHHCCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHCCEEEEECCCHHHHHHH
EEVAREERVREAYLGRRA
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]