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The map label for this gene is ppc

Identifier: 55980595

GI number: 55980595

Start: 596552

End: 599128

Strand: Direct

Name: ppc

Synonym: TTHA0626

Alternate gene names: 55980595

Gene position: 596552-599128 (Clockwise)

Preceding gene: 55980594

Following gene: 55980597

Centisome position: 32.25

GC content: 72.6

Gene sequence:

>2577_bases
GTGAGCCAGGACCCCTTCGCCCTCCTTAAGGCCGAGGTGGACCTCCTCGGCCGCCTCCTCGGGGAGGCCATCCGGACCCT
CTCCGGGGAGCGCTTCTTCGCCCTGGTGGAGGAGGTGCGGGCCCTCGCCAAGGCCCGCCGCCAGGGGGACGAGGCGGCGG
GAGAGGCGCTTCTGGCCCGGGTGGAGGGGCTTTCCACCGAGGAGGCCGAGGCCTTGGTGCGGGCCTTCACCCACTACTTC
CACCTGGTGAACCTGGCGGAGGAGCGGCACCGGGTGCGGGTGAACCGCCTAAGGGCCCAGGCCGAGACCCTGGAAAGCCC
CAGGCCCGAGGGCTTCCTGGCCCTGGCCAAGGCGCTTAAGGAGCGGGGGCTTTCCCTGGAGGAGGCCGAGGCCCACCTGA
ACCGCCTGGAGCTCCTCCTCACCTTCACCGCCCACCCCACGGAGACCCGGCGCCGCACCCTGCGCCACCACCTCGAGGCC
CTGCAGAGGGAGCTGGAGGCGGGGGATAGGGAAAGGCTCGCCGCCCGGGTGGCCCTCCTCTACGGCACGGAGGAGGTGCG
CAAGGCCCGCCCCACGGTGGAGGACGAGATCAAGGGGGGGCTTTACTACCTGCCCACCACCCTGTGGGAGGCCGTGCCCC
GGGTGGTGGCGGGCCTCGAGGCCGCCCTGGAGAGGGTCTACGGGCGAAGGCCCCGCCTGAAAAGCCCCGTGCGCTTTAGG
AGCTGGATCGGCGGCGACCGGGACGGCAACCCCTTCGTCACCCCCGAGGTCACCGCCTTCGCCGGGCGCTACGCCCGGGA
GGTGGCCCGGAGGCGGTTTCTGGAGGCCCTCGAGGACCTCGTGCGCGACCTCTCCCTGGCCGAGGCCCGCGTTCCCGTCC
CCCGGGAGGTGCGGGAGAGGGGAGAGGGGGTGGAGCGCTTCATGGGGGAGCCCTACCGCCGCTACTTCGCCGCCCTGTAC
CGGGCCTTGGAGCGGGAGGAGGCCACCACGGAAGGGCTTCTCGCCGCCCTGAAGGCGGCGGAGCGGGGGCTTAGGGAGGT
GGGGCTTGGCCGGGTGGCGGAGGCCTTCTTGGACCCCTTGGAGGCCCGCCTTTCCGCCTTCGGCCTGGAGCTCGCCCCCC
TGGACCTCAGGGAGGAGTCGGGGAGGCTCCTCGAGGCCGCGGCCGAGCTCCTCCGGGTGGGCGGGGTCCACCCCGACTTC
CTCGCCCTTCCCCAGGAGGAGCGGGAGCGCCTCCTCACCGAGGAGCTCAAGACCGCCCGCCCCCTCCTCCCCGTGGGGGA
GGCCCCGGAGGGGGAGGCCCTAAGGGTGGCCCTGGGGGCCCTGAAGGCCTGGCGGGACAAGGGGGCCCACGTGGTCTCCA
TGACCCATCACCCGGAGGACCTCCTCGCCGTCTTCCTCCTCGCCCGGGAGGTGGGGCTCTACCGCCCCGGCCGGCCCCTG
CCCTTTGACGTGGTCCCCCTCTTTGAGACCCTGGAGGACCTGAGGCGGGCCCCCGGGGTGCTCCGCCGCCTTTTGGAGAA
CCCCGTCTTCCTGGCCCACGCCCGGGGGCGGGGCGGGGTGGAGGTGATGATCGGCTACTCCGACTCCAACAAGGACGCGG
GCTTCCTCATGGCCAACCTCGCCCTCTACGAGGCCCAGGAGGCCTTAAGCCGGGTGGGGGAGGAGGTGGGGCTTCCCGTC
TACTTCTTCCACGGCCGGGGGACCTCCACGGCGAGGGGTGGGGGCCCCGCGGGCCGGGCCATCGCGAGCCTCCCGCCCCG
GAGCGTGGGGCGGAGGATCCGCCTCACGGAGCAGGGGGAGGCCCTGGCGGACCGGTACAGCCACCCCGACCTCGCCGTGC
GCCACCTGGAGCAGATGCTGTACCACTTCGCCCTGGCGGCCCTGGGCCCCGGCCAGGAGCCCGAGGCGCGCTGGCGGGAG
GCCCTGGCCCAGGCGGCGGAGGAGAGCACCCGCCGCTACCGCGCCCTCCTCCAGGAGGAGGGGTTCTTTGACTTCTTTGA
GGCCTTCACCCCCATCCGGGAGATCGGGGAGCTTCCCATCGCCAGCCGCCCCGTGTACCGCCGGGGGCGGGTGCGGGACA
TCCGGGACCTCCGGGCCATCCCTTGGGTCATGGCCTGGACCCAGGTCCGGGTTCTCCTGCCCGGCTGGTACGGCCTCTCC
GCTCTGGAAGAGCTTCCTTTGGACCTTCTCCGGGAGATGTACCGGGGCTGGCCCTTCTTCGCCTCCACCCTGGAGGCCGC
GGCCATGGCCCTCGCCAAGGCGGATATGGGGGTGGCCCGCCTCTATCTGCGCCTGGTCCCCGAGCCCCTGCGGTTCTTCT
ACCGCCGGCTCGCCGAGGAACACGCCCGCACCGTGGCCCTTTTGGAGGCCGTCTTCCAGGCCCCCCTCCTCCACAACCAG
AGGACCCTGGAGCGGCAGATCCGGCTCCGTAACCCCTACGTGGACCCCATCAACATCGTCCAGGTGGAGCTTCTCCGCCG
CTATCGGGCTCCCGGGGGCAAGGAGGACGAGGCCCTGAGGCGGGCCCTTCTCCTCTCCATCCTGGGCGTGGCGGCGGGCC
TCAGGAACGCGGGTTGA

Upstream 100 bases:

>100_bases
CCTTCCGCGCCGCCCAAGGCAAGGCCCGCTTCCACGCCACGGAGCTCGTCTTTGAAGGGGGGAGGCCCGTGGCCATAAGC
CCCTACGTCTGGGAGGAGCC

Downstream 100 bases:

>100_bases
AAACGTCTGCTGGGTTGCCGGCCTAAGGCTTGGGGGCTGCTCCAAGCCGAAGCTCGGTTTGGGGTACCTGCCGTTTTTCT
TCTGGGGCCGGCTCAGGTCT

Product: phosphoenolpyruvate carboxylase

Products: NA

Alternate protein names: PEPC; PEPCase

Number of amino acids: Translated: 858; Mature: 857

Protein sequence:

>858_residues
MSQDPFALLKAEVDLLGRLLGEAIRTLSGERFFALVEEVRALAKARRQGDEAAGEALLARVEGLSTEEAEALVRAFTHYF
HLVNLAEERHRVRVNRLRAQAETLESPRPEGFLALAKALKERGLSLEEAEAHLNRLELLLTFTAHPTETRRRTLRHHLEA
LQRELEAGDRERLAARVALLYGTEEVRKARPTVEDEIKGGLYYLPTTLWEAVPRVVAGLEAALERVYGRRPRLKSPVRFR
SWIGGDRDGNPFVTPEVTAFAGRYAREVARRRFLEALEDLVRDLSLAEARVPVPREVRERGEGVERFMGEPYRRYFAALY
RALEREEATTEGLLAALKAAERGLREVGLGRVAEAFLDPLEARLSAFGLELAPLDLREESGRLLEAAAELLRVGGVHPDF
LALPQEERERLLTEELKTARPLLPVGEAPEGEALRVALGALKAWRDKGAHVVSMTHHPEDLLAVFLLAREVGLYRPGRPL
PFDVVPLFETLEDLRRAPGVLRRLLENPVFLAHARGRGGVEVMIGYSDSNKDAGFLMANLALYEAQEALSRVGEEVGLPV
YFFHGRGTSTARGGGPAGRAIASLPPRSVGRRIRLTEQGEALADRYSHPDLAVRHLEQMLYHFALAALGPGQEPEARWRE
ALAQAAEESTRRYRALLQEEGFFDFFEAFTPIREIGELPIASRPVYRRGRVRDIRDLRAIPWVMAWTQVRVLLPGWYGLS
ALEELPLDLLREMYRGWPFFASTLEAAAMALAKADMGVARLYLRLVPEPLRFFYRRLAEEHARTVALLEAVFQAPLLHNQ
RTLERQIRLRNPYVDPINIVQVELLRRYRAPGGKEDEALRRALLLSILGVAAGLRNAG

Sequences:

>Translated_858_residues
MSQDPFALLKAEVDLLGRLLGEAIRTLSGERFFALVEEVRALAKARRQGDEAAGEALLARVEGLSTEEAEALVRAFTHYF
HLVNLAEERHRVRVNRLRAQAETLESPRPEGFLALAKALKERGLSLEEAEAHLNRLELLLTFTAHPTETRRRTLRHHLEA
LQRELEAGDRERLAARVALLYGTEEVRKARPTVEDEIKGGLYYLPTTLWEAVPRVVAGLEAALERVYGRRPRLKSPVRFR
SWIGGDRDGNPFVTPEVTAFAGRYAREVARRRFLEALEDLVRDLSLAEARVPVPREVRERGEGVERFMGEPYRRYFAALY
RALEREEATTEGLLAALKAAERGLREVGLGRVAEAFLDPLEARLSAFGLELAPLDLREESGRLLEAAAELLRVGGVHPDF
LALPQEERERLLTEELKTARPLLPVGEAPEGEALRVALGALKAWRDKGAHVVSMTHHPEDLLAVFLLAREVGLYRPGRPL
PFDVVPLFETLEDLRRAPGVLRRLLENPVFLAHARGRGGVEVMIGYSDSNKDAGFLMANLALYEAQEALSRVGEEVGLPV
YFFHGRGTSTARGGGPAGRAIASLPPRSVGRRIRLTEQGEALADRYSHPDLAVRHLEQMLYHFALAALGPGQEPEARWRE
ALAQAAEESTRRYRALLQEEGFFDFFEAFTPIREIGELPIASRPVYRRGRVRDIRDLRAIPWVMAWTQVRVLLPGWYGLS
ALEELPLDLLREMYRGWPFFASTLEAAAMALAKADMGVARLYLRLVPEPLRFFYRRLAEEHARTVALLEAVFQAPLLHNQ
RTLERQIRLRNPYVDPINIVQVELLRRYRAPGGKEDEALRRALLLSILGVAAGLRNAG
>Mature_857_residues
SQDPFALLKAEVDLLGRLLGEAIRTLSGERFFALVEEVRALAKARRQGDEAAGEALLARVEGLSTEEAEALVRAFTHYFH
LVNLAEERHRVRVNRLRAQAETLESPRPEGFLALAKALKERGLSLEEAEAHLNRLELLLTFTAHPTETRRRTLRHHLEAL
QRELEAGDRERLAARVALLYGTEEVRKARPTVEDEIKGGLYYLPTTLWEAVPRVVAGLEAALERVYGRRPRLKSPVRFRS
WIGGDRDGNPFVTPEVTAFAGRYAREVARRRFLEALEDLVRDLSLAEARVPVPREVRERGEGVERFMGEPYRRYFAALYR
ALEREEATTEGLLAALKAAERGLREVGLGRVAEAFLDPLEARLSAFGLELAPLDLREESGRLLEAAAELLRVGGVHPDFL
ALPQEERERLLTEELKTARPLLPVGEAPEGEALRVALGALKAWRDKGAHVVSMTHHPEDLLAVFLLAREVGLYRPGRPLP
FDVVPLFETLEDLRRAPGVLRRLLENPVFLAHARGRGGVEVMIGYSDSNKDAGFLMANLALYEAQEALSRVGEEVGLPVY
FFHGRGTSTARGGGPAGRAIASLPPRSVGRRIRLTEQGEALADRYSHPDLAVRHLEQMLYHFALAALGPGQEPEARWREA
LAQAAEESTRRYRALLQEEGFFDFFEAFTPIREIGELPIASRPVYRRGRVRDIRDLRAIPWVMAWTQVRVLLPGWYGLSA
LEELPLDLLREMYRGWPFFASTLEAAAMALAKADMGVARLYLRLVPEPLRFFYRRLAEEHARTVALLEAVFQAPLLHNQR
TLERQIRLRNPYVDPINIVQVELLRRYRAPGGKEDEALRRALLLSILGVAAGLRNAG

Specific function: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle

COG id: COG2352

COG function: function code C; Phosphoenolpyruvate carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PEPCase type 1 family

Homologues:

Organism=Escherichia coli, GI1790393, Length=907, Percent_Identity=36.2734288864388, Blast_Score=438, Evalue=1e-124,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): CAPP_THET2 (Q72L05)

Other databases:

- EMBL:   AE017221
- RefSeq:   YP_004235.1
- ProteinModelPortal:   Q72L05
- SMR:   Q72L05
- STRING:   Q72L05
- GeneID:   2774951
- GenomeReviews:   AE017221_GR
- eggNOG:   COG2352
- HOGENOM:   HBG351035
- OMA:   AIPWVFG
- PhylomeDB:   Q72L05
- ProtClustDB:   CLSK2761883
- BioCyc:   TTHE262724:TT_C0260-MONOMER
- HAMAP:   MF_00595
- InterPro:   IPR021135
- InterPro:   IPR018129
- InterPro:   IPR022805
- InterPro:   IPR015813
- PRINTS:   PR00150

Pfam domain/function: PF00311 PEPcase; SSF51621 Pyrv/PenolPyrv_Kinase_cat

EC number: =4.1.1.31

Molecular weight: Translated: 96535; Mature: 96404

Theoretical pI: Translated: 8.07; Mature: 8.07

Prosite motif: PS00781 PEPCASE_1; PS00393 PEPCASE_2

Important sites: ACT_SITE 145-145 ACT_SITE 531-531

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQDPFALLKAEVDLLGRLLGEAIRTLSGERFFALVEEVRALAKARRQGDEAAGEALLAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VEGLSTEEAEALVRAFTHYFHLVNLAEERHRVRVNRLRAQAETLESPRPEGFLALAKALK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ERGLSLEEAEAHLNRLELLLTFTAHPTETRRRTLRHHLEALQRELEAGDRERLAARVALL
HCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGTEEVRKARPTVEDEIKGGLYYLPTTLWEAVPRVVAGLEAALERVYGRRPRLKSPVRFR
HCCHHHHHCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
SWIGGDRDGNPFVTPEVTAFAGRYAREVARRRFLEALEDLVRDLSLAEARVPVPREVRER
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GEGVERFMGEPYRRYFAALYRALEREEATTEGLLAALKAAERGLREVGLGRVAEAFLDPL
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARLSAFGLELAPLDLREESGRLLEAAAELLRVGGVHPDFLALPQEERERLLTEELKTAR
HHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHCC
PLLPVGEAPEGEALRVALGALKAWRDKGAHVVSMTHHPEDLLAVFLLAREVGLYRPGRPL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCC
PFDVVPLFETLEDLRRAPGVLRRLLENPVFLAHARGRGGVEVMIGYSDSNKDAGFLMANL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHH
ALYEAQEALSRVGEEVGLPVYFFHGRGTSTARGGGPAGRAIASLPPRSVGRRIRLTEQGE
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHCCCCHHHCCEEEECCCCH
ALADRYSHPDLAVRHLEQMLYHFALAALGPGQEPEARWREALAQAAEESTRRYRALLQEE
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFFDFFEAFTPIREIGELPIASRPVYRRGRVRDIRDLRAIPWVMAWTQVRVLLPGWYGLS
CHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ALEELPLDLLREMYRGWPFFASTLEAAAMALAKADMGVARLYLRLVPEPLRFFYRRLAEE
HHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
HARTVALLEAVFQAPLLHNQRTLERQIRLRNPYVDPINIVQVELLRRYRAPGGKEDEALR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RALLLSILGVAAGLRNAG
HHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SQDPFALLKAEVDLLGRLLGEAIRTLSGERFFALVEEVRALAKARRQGDEAAGEALLAR
CCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VEGLSTEEAEALVRAFTHYFHLVNLAEERHRVRVNRLRAQAETLESPRPEGFLALAKALK
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
ERGLSLEEAEAHLNRLELLLTFTAHPTETRRRTLRHHLEALQRELEAGDRERLAARVALL
HCCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGTEEVRKARPTVEDEIKGGLYYLPTTLWEAVPRVVAGLEAALERVYGRRPRLKSPVRFR
HCCHHHHHCCCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
SWIGGDRDGNPFVTPEVTAFAGRYAREVARRRFLEALEDLVRDLSLAEARVPVPREVRER
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
GEGVERFMGEPYRRYFAALYRALEREEATTEGLLAALKAAERGLREVGLGRVAEAFLDPL
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EARLSAFGLELAPLDLREESGRLLEAAAELLRVGGVHPDFLALPQEERERLLTEELKTAR
HHHHHHHCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHCC
PLLPVGEAPEGEALRVALGALKAWRDKGAHVVSMTHHPEDLLAVFLLAREVGLYRPGRPL
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCC
PFDVVPLFETLEDLRRAPGVLRRLLENPVFLAHARGRGGVEVMIGYSDSNKDAGFLMANL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEEECCCCCCCHHHHHHH
ALYEAQEALSRVGEEVGLPVYFFHGRGTSTARGGGPAGRAIASLPPRSVGRRIRLTEQGE
HHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCHHHCCCCHHHCCEEEECCCCH
ALADRYSHPDLAVRHLEQMLYHFALAALGPGQEPEARWREALAQAAEESTRRYRALLQEE
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GFFDFFEAFTPIREIGELPIASRPVYRRGRVRDIRDLRAIPWVMAWTQVRVLLPGWYGLS
CHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ALEELPLDLLREMYRGWPFFASTLEAAAMALAKADMGVARLYLRLVPEPLRFFYRRLAEE
HHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
HARTVALLEAVFQAPLLHNQRTLERQIRLRNPYVDPINIVQVELLRRYRAPGGKEDEALR
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHH
RALLLSILGVAAGLRNAG
HHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA