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The map label for this gene is prsA [H]

Identifier: 55980571

GI number: 55980571

Start: 569416

End: 570429

Strand: Direct

Name: prsA [H]

Synonym: TTHA0602

Alternate gene names: 55980571

Gene position: 569416-570429 (Clockwise)

Preceding gene: 55980566

Following gene: 55980576

Centisome position: 30.78

GC content: 74.65

Gene sequence:

>1014_bases
ATGAACCACACGGGGGGCCTCGGGGTGGGCTCGCCCCGGGCGGCCCGGAGGATGAGGTCGTTCACGAGGTCCATGCTAGC
ATGGGGCATGCGCGCGTTTCTTTTGGCCCTGACCTTGCTCCTCGTCCCCATGGCCCTGGCCCAGGGGGAGGTGGTGGCCC
AGGTGGGCCCCGAGGCGATCACCCGGGAAGCCTTTGAGCTCCGCTACGGCCTCTTCGTGCGGAGCGCCCTGGCCCAGCTC
GGCCTGCCCGACACGGAGGAGGCCCGGGCCCTCCTCGCCGCCTACCGGCCGGCCTTCCTCGAGGCCCTGGCCCGGGAAAA
GGCCCTCCTCCAGCGGGCCCGGGAGGAGGGGCTCTACCCGGACCCCGCCGCCGTTGAGGCCCGGGTCCACGCCCTGAAGG
AGGCCTTCCCCGAGGAGGAGGCCCTGGAGGAGGCGCTCCGCCAGGCGGGGGTCCCGGGGCTTGAGGCCTACCGCAGGCTC
GTGGCCGAGGCCATGGCCCTCGAGGCCCTGGAGGCCCGGTACCGCTCCCGGATCGCCGTCTCCCGGGCGGCCCTCAAGGC
CCTTTGGCTCCTCTCCCCGGAGTACCGCCACCCCACCCTCTACTGCGCCCGGCACCTCCTCGTCCCCACCCGGGAGGAGG
TGGAGGAGGCCCGCCTGCGGCTTGCCCGTGGGGAGGCCTTCGCCGAGGTGGCCCGGGCGGTCTCCCAGGACCCGGGCTCC
AGGGAGGAGGGCGGGGACCTGGGGTGCGCCCCCGAGGGCACCTACGTCCCCGCCTTTGAGGAGGCCCTCGTGCGCCTCCG
GCCCGGGGAGGTCTCGGGCCCCGTGCGGACGGAGTTCGGCTACCACCTGATCCTCCTGGAGCGGGTGGTCCCTCCGGGCC
GCTACCCCTTGGAGGAGGTGGCCCCGCTTCTGGAGAAGGAGGTGGCGGACCGGGCCTGGGAGCGGCTCGAGGAGGCCCTG
GTCCGGGCCGTGCCCGTGCGCCTCTACCCCGAGCGCCTAGAGGCGGAGGAGTAG

Upstream 100 bases:

>100_bases
GGTCACCTCGGCGCAGACCTCGGGGTTTTGCACGATCTCGGGGAGGGTGTAGCGCTCGCGGAGCTTCCGGTAGGCCTTCT
GGTAGCGCCCGGCCTGGCGC

Downstream 100 bases:

>100_bases
GGCCTCGTCCCCGGTGGGGGCCTGGGCCAGGAGGAGGGCCTCCCCGGGGGCGTAGATCCCGCTTCGCCCCTGGAAGCCAA
GGCCCGCCACCTCCCCGTTC

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNHTGGLGVGSPRAARRMRSFTRSMLAWGMRAFLLALTLLLVPMALAQGEVVAQVGPEAITREAFELRYGLFVRSALAQL
GLPDTEEARALLAAYRPAFLEALAREKALLQRAREEGLYPDPAAVEARVHALKEAFPEEEALEEALRQAGVPGLEAYRRL
VAEAMALEALEARYRSRIAVSRAALKALWLLSPEYRHPTLYCARHLLVPTREEVEEARLRLARGEAFAEVARAVSQDPGS
REEGGDLGCAPEGTYVPAFEEALVRLRPGEVSGPVRTEFGYHLILLERVVPPGRYPLEEVAPLLEKEVADRAWERLEEAL
VRAVPVRLYPERLEAEE

Sequences:

>Translated_337_residues
MNHTGGLGVGSPRAARRMRSFTRSMLAWGMRAFLLALTLLLVPMALAQGEVVAQVGPEAITREAFELRYGLFVRSALAQL
GLPDTEEARALLAAYRPAFLEALAREKALLQRAREEGLYPDPAAVEARVHALKEAFPEEEALEEALRQAGVPGLEAYRRL
VAEAMALEALEARYRSRIAVSRAALKALWLLSPEYRHPTLYCARHLLVPTREEVEEARLRLARGEAFAEVARAVSQDPGS
REEGGDLGCAPEGTYVPAFEEALVRLRPGEVSGPVRTEFGYHLILLERVVPPGRYPLEEVAPLLEKEVADRAWERLEEAL
VRAVPVRLYPERLEAEE
>Mature_337_residues
MNHTGGLGVGSPRAARRMRSFTRSMLAWGMRAFLLALTLLLVPMALAQGEVVAQVGPEAITREAFELRYGLFVRSALAQL
GLPDTEEARALLAAYRPAFLEALAREKALLQRAREEGLYPDPAAVEARVHALKEAFPEEEALEEALRQAGVPGLEAYRRL
VAEAMALEALEARYRSRIAVSRAALKALWLLSPEYRHPTLYCARHLLVPTREEVEEARLRLARGEAFAEVARAVSQDPGS
REEGGDLGCAPEGTYVPAFEEALVRLRPGEVSGPVRTEFGYHLILLERVVPPGRYPLEEVAPLLEKEVADRAWERLEEAL
VRAVPVRLYPERLEAEE

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=95, Percent_Identity=43.1578947368421, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 37417; Mature: 37417

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHTGGLGVGSPRAARRMRSFTRSMLAWGMRAFLLALTLLLVPMALAQGEVVAQVGPEAI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHH
TREAFELRYGLFVRSALAQLGLPDTEEARALLAAYRPAFLEALAREKALLQRAREEGLYP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPAAVEARVHALKEAFPEEEALEEALRQAGVPGLEAYRRLVAEAMALEALEARYRSRIAV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAALKALWLLSPEYRHPTLYCARHLLVPTREEVEEARLRLARGEAFAEVARAVSQDPGS
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
REEGGDLGCAPEGTYVPAFEEALVRLRPGEVSGPVRTEFGYHLILLERVVPPGRYPLEEV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCHHHH
APLLEKEVADRAWERLEEALVRAVPVRLYPERLEAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC
>Mature Secondary Structure
MNHTGGLGVGSPRAARRMRSFTRSMLAWGMRAFLLALTLLLVPMALAQGEVVAQVGPEAI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCHHHH
TREAFELRYGLFVRSALAQLGLPDTEEARALLAAYRPAFLEALAREKALLQRAREEGLYP
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPAAVEARVHALKEAFPEEEALEEALRQAGVPGLEAYRRLVAEAMALEALEARYRSRIAV
CHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRAALKALWLLSPEYRHPTLYCARHLLVPTREEVEEARLRLARGEAFAEVARAVSQDPGS
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
REEGGDLGCAPEGTYVPAFEEALVRLRPGEVSGPVRTEFGYHLILLERVVPPGRYPLEEV
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHCCCCCCCHHHH
APLLEKEVADRAWERLEEALVRAVPVRLYPERLEAEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA