Click here to switch to the map view.

The map label for this gene is udk

Identifier: 55980547

GI number: 55980547

Start: 546344

End: 546979

Strand: Reverse

Name: udk

Synonym: TTHA0578

Alternate gene names: 55980547

Gene position: 546979-546344 (Counterclockwise)

Preceding gene: 55980548

Following gene: 55980546

Centisome position: 29.57

GC content: 69.81

Gene sequence:

>636_bases
GTGAGCGCGCCCAAGCCCTTCGTCATCGGGATCGCCGGGGGAACGGCGAGCGGCAAGACCACCCTCGCCCAGGCCCTGGC
CCGGACCCTGGGGGAGCGGGTCGCCCTCCTCCCCATGGACCACTACTACAAGGACCTGGGCCACCTCCCCCTGGAGGAGC
GCCTCCGGGTGAACTACGACCACCCGGACGCCTTTGACCTCGCCCTCTACCTGGAGCACGCCCAGGCCCTCCTCCGGGGC
CTTCCCGTGGAGATGCCCGTCTACGACTTCCGGGCCTACACCCGAAGCCCCAGAAGAACGCCGGTCCGGCCCGCCCCCGT
GGTGATCCTGGAAGGCATCCTGGTCCTCTACCCCAAGGAGCTCCGGGACCTCATGGACCTCAAGGTCTTCGTGGACGCCG
ACGCCGACGAGCGCTTCATCCGCAGGCTCAAGCGGGACGTCCTGGAAAGGGGCAGGAGCCTGGAAGGGGTGGTGGCCCAG
TACCTGGAGCAGGTCAAGCCCATGCACCTCCACTTCGTGGAGCCCACCAAGCGGTACGCCGACGTGATCGTGCCCAGGGG
CGGCCAGAACCCCGTGGCCCTGGAGATGCTCGCGGCCAAGGCCCTCGCCCGCCTGGCCCGGATGGGGGCAGCGTGA

Upstream 100 bases:

>100_bases
ACAAGACCATCGGCCACGCCCAGGAGCGGGCGGCCGTGGCCCGCTAGGGCCCGAGGGGAATGGGGGCGGGGGCTTCCCCC
CGCCCCTTTATCATGGAGGG

Downstream 100 bases:

>100_bases
GGGCCCTCCTCCACCTCCTCCTCGTCCTCGCCCTCCTCCCCTCCCTCCTCGCCCTCGCGCCGAGGCTCCGCGCCCAGGCC
CCGGGGCCCGTGGCCCTGGT

Product: uridine kinase

Products: NA

Alternate protein names: Cytidine monophosphokinase; Uridine monophosphokinase

Number of amino acids: Translated: 211; Mature: 210

Protein sequence:

>211_residues
MSAPKPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYDHPDAFDLALYLEHAQALLRG
LPVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKELRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQ
YLEQVKPMHLHFVEPTKRYADVIVPRGGQNPVALEMLAAKALARLARMGAA

Sequences:

>Translated_211_residues
MSAPKPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYDHPDAFDLALYLEHAQALLRG
LPVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKELRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQ
YLEQVKPMHLHFVEPTKRYADVIVPRGGQNPVALEMLAAKALARLARMGAA
>Mature_210_residues
SAPKPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYDHPDAFDLALYLEHAQALLRGL
PVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKELRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQY
LEQVKPMHLHFVEPTKRYADVIVPRGGQNPVALEMLAAKALARLARMGAA

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uridine kinase family

Homologues:

Organism=Homo sapiens, GI18699734, Length=206, Percent_Identity=43.2038834951456, Blast_Score=181, Evalue=3e-46,
Organism=Homo sapiens, GI57863312, Length=206, Percent_Identity=41.747572815534, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI301129207, Length=206, Percent_Identity=41.747572815534, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI13899253, Length=203, Percent_Identity=44.8275862068966, Blast_Score=171, Evalue=5e-43,
Organism=Homo sapiens, GI209863022, Length=150, Percent_Identity=42.6666666666667, Blast_Score=122, Evalue=3e-28,
Organism=Escherichia coli, GI87082034, Length=203, Percent_Identity=49.7536945812808, Blast_Score=209, Evalue=8e-56,
Organism=Caenorhabditis elegans, GI17539894, Length=211, Percent_Identity=43.1279620853081, Blast_Score=179, Evalue=9e-46,
Organism=Caenorhabditis elegans, GI17539892, Length=211, Percent_Identity=43.1279620853081, Blast_Score=179, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI71981181, Length=207, Percent_Identity=36.7149758454106, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6324339, Length=194, Percent_Identity=36.0824742268041, Blast_Score=121, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6320223, Length=191, Percent_Identity=25.6544502617801, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28573516, Length=208, Percent_Identity=45.1923076923077, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28573514, Length=208, Percent_Identity=45.1923076923077, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28573512, Length=208, Percent_Identity=45.1923076923077, Blast_Score=182, Evalue=1e-46,
Organism=Drosophila melanogaster, GI45550449, Length=208, Percent_Identity=45.1923076923077, Blast_Score=182, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24649624, Length=220, Percent_Identity=40.9090909090909, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI221458995, Length=206, Percent_Identity=42.2330097087379, Blast_Score=168, Evalue=3e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URK_THET2 (Q72L53)

Other databases:

- EMBL:   AE017221
- RefSeq:   YP_004185.1
- HSSP:   Q9BZX2
- ProteinModelPortal:   Q72L53
- STRING:   Q72L53
- GeneID:   2774557
- GenomeReviews:   AE017221_GR
- eggNOG:   COG0572
- HOGENOM:   HBG527126
- OMA:   NQFVEPT
- PhylomeDB:   Q72L53
- ProtClustDB:   PRK05480
- BioCyc:   TTHE262724:TT_C0210-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00551
- InterPro:   IPR003593
- InterPro:   IPR006083
- InterPro:   IPR000764
- PANTHER:   PTHR10285:SF6
- PRINTS:   PR00988
- SMART:   SM00382
- TIGRFAMs:   TIGR00235

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.48

Molecular weight: Translated: 23674; Mature: 23543

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPKPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYD
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHCCCCHHHHHEECCC
HPDAFDLALYLEHAQALLRGLPVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKE
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHH
LRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQYLEQVKPMHLHFVEPTKRYA
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECHHHHHH
DVIVPRGGQNPVALEMLAAKALARLARMGAA
HEECCCCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAPKPFVIGIAGGTASGKTTLAQALARTLGERVALLPMDHYYKDLGHLPLEERLRVNYD
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHEEECCHHHHHHHHCCCCHHHHHEECCC
HPDAFDLALYLEHAQALLRGLPVEMPVYDFRAYTRSPRRTPVRPAPVVILEGILVLYPKE
CCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCHH
LRDLMDLKVFVDADADERFIRRLKRDVLERGRSLEGVVAQYLEQVKPMHLHFVEPTKRYA
HHHHHHHHHEEECCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEEECHHHHHH
DVIVPRGGQNPVALEMLAAKALARLARMGAA
HEECCCCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA