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The map label for this gene is glnS [H]

Identifier: 55980518

GI number: 55980518

Start: 511785

End: 513431

Strand: Reverse

Name: glnS [H]

Synonym: TTHA0549

Alternate gene names: 55980518

Gene position: 513431-511785 (Counterclockwise)

Preceding gene: 55980519

Following gene: 55980515

Centisome position: 27.76

GC content: 65.76

Gene sequence:

>1647_bases
ATGGGCCTTGTCCCCGAGTGCTTCATCACCGAGCTCGTGGAGCGGGACCTCAAGGAGGGGAAGTACGCCAAGCTCGTCAC
CCGCTTCCCCCCGGAGCCCAACGGCTACCTCCACATCGGCCACGCCCGGAGCATCGTTTTGAACTTCGGCCTCGCCCAGG
ACTACGGCGGGGAGTGCAACCTGCGCTTTGACGACACCAACCCCGAGACGGAGAAGGAGGAGTACGCCCGGGCCATTGAG
GAGGACGTGCGCTGGCTGGGCTTCCGGCCCACCCGGGTCCTCTACGCCTCGGACTACTTTGAGACCATGTACCAATGCGC
CCTGGTCCTCATCCAGGAGGGCAAGGCCTACGTGGACGACCTCCCGGAGGAGGAGATGAGCGAGCTTCGGGCCCAGGGAA
AGCCAAGCCCCTACCGGGAGCGGAGCGTGGAGGAGAACCTGGAGCTCTTTGAGAGGATGCGCCGGGGGGAGTTCCCCACG
GGAAGCCGGGTCTTAAGGGCCAAGATTGACCCCGCCCACCCCAACTTCAAGCTCCGCGACCCCGTGCTCTACCGCATCGT
CCACGCCCCCCACTACCACGTTGGGGACCGGTGGGTCATCTACCCCATGTACGACTTCGCCCACCCCCTGGAGGACTTCA
TCGAGGGGGTCACCCACTCCCTCTGCACCCTGGAGTTTGAGAACAACCGCACCGTCTACGACTGGGTCATTGAGAACCTC
AAGGGGAAGTGTGGGCTTCCCACCTCCCCCAGGCCCCACCAGTACGAGTTCGCCCGGCTGGACTTAAGCCACACCGTGCT
CTCCAAGAGGAAGCTCATCAAGCTGGTGGAAGGGGGGTACGTCTCGGGCTGGGACGACCCCAGGCTCCCCACCCTGAGGG
GCCTGAGGCGGAGGGGGGTGAGGCCCGAGGCCATCGTGGAGTTCGTGCGCAAGACGGGGATCTCCAGGAACGAGGCCCAG
ATAGAGATGGACCTCTTTGAGGAGGTGGTGCGGGACGACCTGAACCCCATCGCCCCCAGGGTCTTGGGCGTGGTGGACCC
CCTGAAGGTGGTCCTCACCAACTACGAGGGGGAGGAGTGGATAGAGGCCCCCTACTGGCCCCGGGACATCCCCAAGGAGG
GGACGAGGCCCCTTCCCTTCTCCCCGGAGCTCTACATTGAGCGCACGGACTTCAGCCTCAACCCCCCTAAAGGTTGGAAG
CGCCTCGCCCCAGGGCAGAGGGTGCGCCTGAGGCACGCCTACGTCATAGAGCTTGAGGACGTGGTGGAAGAGGGGGGCGA
GGTGAGGCTCCTCAAGGCCCGGATCGTCCCCGGCACCCTGGGGGCGAACCCCGAGGACGGGGTCAGGCCCAAGGGGGTGA
TCCACTGGGTCTCCGCCCGCCACGCCCTCCCCGTGGAGTTTAGGCTCTACGGCAGGCTCTTCCGCACCAAGGACCCGGAG
GAGGGGGGGGACTTCCTGCAAAACCTCAACCCCGAGGCCCTTGTGGTGAAGCGGGGCTTCATTGAGCCGAGCGTGGCCCA
GGACCCCGAGGACACCCGCTACCAGCTGGAGCGCCTGGGCTACTTCTGGCGGGACCCCGTGGACTCGAGGCCCGAGGCCC
TGGTGATGAACCGCATCGTGCCCCTAAAAGAGGGGTATAGGGTCTGA

Upstream 100 bases:

>100_bases
GCCCTCGCCAACGCCTGGGTGCGGGAGACCGGGGACCTGAAGGAGGGCATCCGGGCCTTCTTTGAGAAGCGGCCCCCCAG
GTTCTGAGTAGACTCTCCTT

Downstream 100 bases:

>100_bases
CCCCGGTCGCCCACTCGGCCGTCACCGGACATCCCCGCCAGGGCTTTTTGCCAGGGTCCCCAGGCCGGCCTTGGCCGGCC
TGGGGTGGCTTTAAAGCCCC

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 548; Mature: 547

Protein sequence:

>548_residues
MGLVPECFITELVERDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRFDDTNPETEKEEYARAIE
EDVRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDDLPEEEMSELRAQGKPSPYRERSVEENLELFERMRRGEFPT
GSRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYHVGDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENL
KGKCGLPTSPRPHQYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGVRPEAIVEFVRKTGISRNEAQ
IEMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEGEEWIEAPYWPRDIPKEGTRPLPFSPELYIERTDFSLNPPKGWK
RLAPGQRVRLRHAYVIELEDVVEEGGEVRLLKARIVPGTLGANPEDGVRPKGVIHWVSARHALPVEFRLYGRLFRTKDPE
EGGDFLQNLNPEALVVKRGFIEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIVPLKEGYRV

Sequences:

>Translated_548_residues
MGLVPECFITELVERDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRFDDTNPETEKEEYARAIE
EDVRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDDLPEEEMSELRAQGKPSPYRERSVEENLELFERMRRGEFPT
GSRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYHVGDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENL
KGKCGLPTSPRPHQYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGVRPEAIVEFVRKTGISRNEAQ
IEMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEGEEWIEAPYWPRDIPKEGTRPLPFSPELYIERTDFSLNPPKGWK
RLAPGQRVRLRHAYVIELEDVVEEGGEVRLLKARIVPGTLGANPEDGVRPKGVIHWVSARHALPVEFRLYGRLFRTKDPE
EGGDFLQNLNPEALVVKRGFIEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIVPLKEGYRV
>Mature_547_residues
GLVPECFITELVERDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRFDDTNPETEKEEYARAIEE
DVRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDDLPEEEMSELRAQGKPSPYRERSVEENLELFERMRRGEFPTG
SRVLRAKIDPAHPNFKLRDPVLYRIVHAPHYHVGDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENLK
GKCGLPTSPRPHQYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGVRPEAIVEFVRKTGISRNEAQI
EMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEGEEWIEAPYWPRDIPKEGTRPLPFSPELYIERTDFSLNPPKGWKR
LAPGQRVRLRHAYVIELEDVVEEGGEVRLLKARIVPGTLGANPEDGVRPKGVIHWVSARHALPVEFRLYGRLFRTKDPEE
GGDFLQNLNPEALVVKRGFIEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIVPLKEGYRV

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=528, Percent_Identity=46.4015151515151, Blast_Score=417, Evalue=1e-116,
Organism=Homo sapiens, GI62241042, Length=514, Percent_Identity=35.408560311284, Blast_Score=296, Evalue=3e-80,
Organism=Escherichia coli, GI1786895, Length=549, Percent_Identity=51.5482695810565, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI1788743, Length=108, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17543332, Length=537, Percent_Identity=41.7132216014898, Blast_Score=400, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17511007, Length=511, Percent_Identity=32.2896281800391, Blast_Score=257, Evalue=9e-69,
Organism=Saccharomyces cerevisiae, GI6324742, Length=569, Percent_Identity=39.1915641476274, Blast_Score=373, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321192, Length=529, Percent_Identity=37.2400756143667, Blast_Score=313, Evalue=4e-86,
Organism=Drosophila melanogaster, GI17864488, Length=548, Percent_Identity=41.7883211678832, Blast_Score=404, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24649466, Length=377, Percent_Identity=39.5225464190981, Blast_Score=266, Evalue=3e-71,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 63470; Mature: 63339

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLVPECFITELVERDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECN
CCCCHHHHHHHHHHHHHHCCCCEEHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCCEEE
LRFDDTNPETEKEEYARAIEEDVRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDD
EEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHC
LPEEEMSELRAQGKPSPYRERSVEENLELFERMRRGEFPTGSRVLRAKIDPAHPNFKLRD
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEECC
PVLYRIVHAPHYHVGDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENL
CCEEHEECCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHC
KGKCGLPTSPRPHQYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGV
CCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHCCC
RPEAIVEFVRKTGISRNEAQIEMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEGEEW
CHHHHHHHHHHHCCCCCHHHEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
IEAPYWPRDIPKEGTRPLPFSPELYIERTDFSLNPPKGWKRLAPGQRVRLRHAYVIELED
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCEEEEEEEEEEEEHH
VVEEGGEVRLLKARIVPGTLGANPEDGVRPKGVIHWVSARHALPVEFRLYGRLFRTKDPE
HHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCC
EGGDFLQNLNPEALVVKRGFIEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIV
CHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHHCCC
PLKEGYRV
CCCCCCCC
>Mature Secondary Structure 
GLVPECFITELVERDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECN
CCCHHHHHHHHHHHHHHCCCCEEHHCCCCCCCCCEEEECCCEEEEEECCCCCCCCCEEE
LRFDDTNPETEKEEYARAIEEDVRWLGFRPTRVLYASDYFETMYQCALVLIQEGKAYVDD
EEECCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHC
LPEEEMSELRAQGKPSPYRERSVEENLELFERMRRGEFPTGSRVLRAKIDPAHPNFKLRD
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCEECC
PVLYRIVHAPHYHVGDRWVIYPMYDFAHPLEDFIEGVTHSLCTLEFENNRTVYDWVIENL
CCEEHEECCCCEECCCEEEEEECHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHC
KGKCGLPTSPRPHQYEFARLDLSHTVLSKRKLIKLVEGGYVSGWDDPRLPTLRGLRRRGV
CCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHCCC
RPEAIVEFVRKTGISRNEAQIEMDLFEEVVRDDLNPIAPRVLGVVDPLKVVLTNYEGEEW
CHHHHHHHHHHHCCCCCHHHEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHH
IEAPYWPRDIPKEGTRPLPFSPELYIERTDFSLNPPKGWKRLAPGQRVRLRHAYVIELED
CCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCHHHCCCCCEEEEEEEEEEEEHH
VVEEGGEVRLLKARIVPGTLGANPEDGVRPKGVIHWVSARHALPVEFRLYGRLFRTKDPE
HHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCC
EGGDFLQNLNPEALVVKRGFIEPSVAQDPEDTRYQLERLGYFWRDPVDSRPEALVMNRIV
CHHHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCCCCHHHHHHCCC
PLKEGYRV
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA