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The map label for this gene is rsmC [H]

Identifier: 55980502

GI number: 55980502

Start: 495541

End: 496668

Strand: Reverse

Name: rsmC [H]

Synonym: TTHA0533

Alternate gene names: 55980502

Gene position: 496668-495541 (Counterclockwise)

Preceding gene: 55980505

Following gene: 55980501

Centisome position: 26.85

GC content: 70.83

Gene sequence:

>1128_bases
GTGAGCCTGACGCGGGAAGCCTACCACCGCCTCACCCCCCTTCCCCACCCCGGGGGCCGGCTCTTCATCAAGCCCGGGGC
CCGGGGGTACCGGGACCCGGTCCACGACCTCCTGCAGAAGACGGTGGAGCCCTTCGGCGAGCGGGCCCTGGACCTGAACC
CCGGGGTGGGCTGGGGAAGCCTCCCCTTGGAGGGGAGGATGGCGGTGGAGCGGCTGGAGACCTCCCGGGCCGCCTTCCGC
TGCCTCACGGCGAGCGGCCTCCAGGCCCGGCTCGCCCTTCCCTGGGAGGCGGCGGCGGGAGCATACGACCTCGTGGTCCT
GGCCCTCCCCGCCGGGAGAGGGACGGCCTATGTCCAGGCGAGCCTCGTGGCCGCGGCCCGGGCCCTCCGGATGGGAGGAC
GGCTCTACCTCGCCGGGGACAAGAACAAGGGGTTTGAGCGCTACTTCAAGGAGGCCCGGGCCCTTCTGGGCTACGGCGTG
GTGGTGCGGCGGGAGGGGCCCTACCGGGTGGCCCTCCTGGAGAAGGAGAAGGAGGCCCCGCCCCTCCCCTCCCTCTGGCG
GGCCTTTTCCGCCCGCATCCTGGGGGCGGAGTACACCTTCCACCACCTCCCCGGGGTCTTCTCGGCGGGGAAGGTGGACC
CGGCCTCCCTGCTCCTCCTCGAGGCCCTGCAGGAACGCCTGGGGCCCGAGGGGGTCCGCGGCCGGCAGGTCCTGGACCTG
GGGGCGGGCTATGGGGCCCTGACCCTGCCCCTCGCCCGGATGGGGGCGGAGGTGGTGGGGGTGGAGGACGACCTGGCCTC
CGTCCTCTCCCTGCAAAAGGGCCTCGAGGCCAACGCCCTGAAGGCCCAGGCCCTCCACTCCGACGTGGACGAGGCCTTGA
CAGAAGAGGCCCGGTTTGACATCATAGTTACGAACCCCCCCTTTCACGTGGGGGGTGCGGTCATTCTGGATGTGGCCCAG
GCGTTCGTGAACGTGGCGGCGGCCCGGCTCAGGCCGGGTGGCGTGTTTTTCCTCGTGTCCAACCCGTTCCTGAAGTACGA
GCCTTTGCTGGAGGAGAAGTTCGGCGCCTTCCAGACCCTCAAGGTGGCCGAATACAAGGTCCTGTTCGCGGAAAAGCGAG
GGAGGTGA

Upstream 100 bases:

>100_bases
CCAGGGCCACGCTTCCCTCCTTCCCCGCCCCCCCGGGCGGTTTGAAAGAGAATGTTAGCACATTTGCCCCCTCCGCCCAA
GGCCCTTATCCTGGGAGGAC

Downstream 100 bases:

>100_bases
GCCTTGAAGAAGAGCAAGCGCAAGAACGCCCAGGCCCAGGAGGCCCAGGAGACCGAGGTCCTGGTCCAGGAGGAGGCGGA
GGAACTCCCCGAGTTCCCCG

Product: ribosomal RNA small subunit methyltransferase

Products: NA

Alternate protein names: 16S rRNA m2G1207 methyltransferase; rRNA (guanine-N(2)-)-methyltransferase rsmC [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MSLTREAYHRLTPLPHPGGRLFIKPGARGYRDPVHDLLQKTVEPFGERALDLNPGVGWGSLPLEGRMAVERLETSRAAFR
CLTASGLQARLALPWEAAAGAYDLVVLALPAGRGTAYVQASLVAAARALRMGGRLYLAGDKNKGFERYFKEARALLGYGV
VVRREGPYRVALLEKEKEAPPLPSLWRAFSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERLGPEGVRGRQVLDL
GAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEALTEEARFDIIVTNPPFHVGGAVILDVAQ
AFVNVAAARLRPGGVFFLVSNPFLKYEPLLEEKFGAFQTLKVAEYKVLFAEKRGR

Sequences:

>Translated_375_residues
MSLTREAYHRLTPLPHPGGRLFIKPGARGYRDPVHDLLQKTVEPFGERALDLNPGVGWGSLPLEGRMAVERLETSRAAFR
CLTASGLQARLALPWEAAAGAYDLVVLALPAGRGTAYVQASLVAAARALRMGGRLYLAGDKNKGFERYFKEARALLGYGV
VVRREGPYRVALLEKEKEAPPLPSLWRAFSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERLGPEGVRGRQVLDL
GAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEALTEEARFDIIVTNPPFHVGGAVILDVAQ
AFVNVAAARLRPGGVFFLVSNPFLKYEPLLEEKFGAFQTLKVAEYKVLFAEKRGR
>Mature_374_residues
SLTREAYHRLTPLPHPGGRLFIKPGARGYRDPVHDLLQKTVEPFGERALDLNPGVGWGSLPLEGRMAVERLETSRAAFRC
LTASGLQARLALPWEAAAGAYDLVVLALPAGRGTAYVQASLVAAARALRMGGRLYLAGDKNKGFERYFKEARALLGYGVV
VRREGPYRVALLEKEKEAPPLPSLWRAFSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERLGPEGVRGRQVLDLG
AGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEALTEEARFDIIVTNPPFHVGGAVILDVAQA
FVNVAAARLRPGGVFFLVSNPFLKYEPLLEEKFGAFQTLKVAEYKVLFAEKRGR

Specific function: Specifically methylates the guanosine in position 1207 of 16S rRNA in the 30S particle [H]

COG id: COG2813

COG function: function code J; 16S RNA G1207 methylase RsmC

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmC family [H]

Homologues:

Organism=Escherichia coli, GI1790830, Length=291, Percent_Identity=28.8659793814433, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI87082206, Length=202, Percent_Identity=29.7029702970297, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR013675
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS; PF08468 MTS_N [H]

EC number: =2.1.1.172 [H]

Molecular weight: Translated: 40657; Mature: 40525

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS01131 RRNA_A_DIMETH ; PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTREAYHRLTPLPHPGGRLFIKPGARGYRDPVHDLLQKTVEPFGERALDLNPGVGWGS
CCCCHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCC
LPLEGRMAVERLETSRAAFRCLTASGLQARLALPWEAAAGAYDLVVLALPAGRGTAYVQA
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCEEEEEEEECCCCCCHHHHH
SLVAAARALRMGGRLYLAGDKNKGFERYFKEARALLGYGVVVRREGPYRVALLEKEKEAP
HHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCEEEEEEECCCCCC
PLPSLWRAFSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERLGPEGVRGRQVLDL
CCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
GAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEALTEEARFD
CCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEE
IIVTNPPFHVGGAVILDVAQAFVNVAAARLRPGGVFFLVSNPFLKYEPLLEEKFGAFQTL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCHHEE
KVAEYKVLFAEKRGR
EHHHEEEEEECCCCC
>Mature Secondary Structure 
SLTREAYHRLTPLPHPGGRLFIKPGARGYRDPVHDLLQKTVEPFGERALDLNPGVGWGS
CCCHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCCCC
LPLEGRMAVERLETSRAAFRCLTASGLQARLALPWEAAAGAYDLVVLALPAGRGTAYVQA
CCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCEEEEEEEECCCCCCHHHHH
SLVAAARALRMGGRLYLAGDKNKGFERYFKEARALLGYGVVVRREGPYRVALLEKEKEAP
HHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHCCEEEECCCCEEEEEEECCCCCC
PLPSLWRAFSARILGAEYTFHHLPGVFSAGKVDPASLLLLEALQERLGPEGVRGRQVLDL
CCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
GAGYGALTLPLARMGAEVVGVEDDLASVLSLQKGLEANALKAQALHSDVDEALTEEARFD
CCCCCHHHHHHHHCCCEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEE
IIVTNPPFHVGGAVILDVAQAFVNVAAARLRPGGVFFLVSNPFLKYEPLLEEKFGAFQTL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHCCCHHEE
KVAEYKVLFAEKRGR
EHHHEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA