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The map label for this gene is paaK [H]

Identifier: 55980480

GI number: 55980480

Start: 475498

End: 476640

Strand: Reverse

Name: paaK [H]

Synonym: TTHA0511

Alternate gene names: 55980480

Gene position: 476640-475498 (Counterclockwise)

Preceding gene: 55980481

Following gene: 55980479

Centisome position: 25.77

GC content: 69.12

Gene sequence:

>1143_bases
GTGGATGTGGACCGGCTTGCGAGGTTCAGAGAAGTGGTGGCCAAGGCGAAGGCCCACCCCGTCTACCGGGAGAAGCTCCG
CGACGTGGACCCGGAGAAGCTCACCCTAAAGGACCTCTCCTCCCTCCCCCCCACCACCCGGGAGGAGTGGCTCGCCTACC
TCGGGGAAAACCCCAAGCCCCCGGAAGGGGCGAGCCTCATGCACCTCACCCCAAGCCCCGTCCTGGGCTGGATGCCCGAG
TACCTCTCCCAGGAGGACCTCCACTACCAGGCCGAGGCCCTGGCGGCGCACTACAGAAGGCTCGGCCTCGTGGGCAAGAA
GGTGCTTGTGGCCTTCAGCTACCACGTCTTCGCGGGGGGGTGGCTCTTCCACCAGGCCCTTTGGCGGGCGGGGAACCTGG
TCTTTCCCCACGGGCCCGGGGAGGCGAAGCGGGTGGCGGAGCTCGGGGAGCGCTACGGCTTTGACGTCCTCGTCACCAAC
CCCTCCTTCGCCCTGAAGGTGGCCCAGGCGGGAGGGCGCTTCCCCTTGCTCCTTGCCGGGGGGGAGCCCTTCACCTCCGT
GCCGGGCTTCAGGGAGCGGGTGGAGGAGGCCCTGGGGGGCGTGGCCCTGGACGCCTACGGCACCAGCGAGCTCGGCATCG
TGGCCGGGGAGCGGCCCGAAAAGGACGGGCTCTGGGAGATCCCGGAGATGGCCGTCCTCGAGGTCCTGGACCCCGAGACC
TTAAGGCCCGTGGCGGACGGGGAAAAGGGGGAGCTCGTGGTCACCGCCTTAAGCCGCACCCTCATGCCCATGGTGCGCTT
CCGCACCGGGGACCTGGCGGTGGCGGAAAGGCGGGAGGGCCTCACGGTGCTTCCCCGCGGGGTCTTCGGCCGCACGGACC
AGATGGTGAAGGTGAAGGGGGTCAAGCTCTACCCCACGGAGCTCGCCCCCGTCCTGGCGGGGTTTGGCCTGGACCCCAAG
GGCTTCCAGGTGGTGGTGGAGAGGAAGCTGGAAGGCACCGACAAGCTCGTCCTCCGCCTCAAGGCGGAAAAGGTCCCCCC
CGGCCTCTTTGAGGCCATCCAGAAGGCCACGGGGCTCAAGGTGGACGAGGTGGAGCTGGTGGAAACCCTGGAAGGGGGCC
TCCTGGTGGACCGCCGCTTCTGA

Upstream 100 bases:

>100_bases
GGGTCTTCACCGCGCCCCTGGAGGAGGTCCTGAAGCGGGTGGTGCCCCTCTAACGCCAAGCCCCCGCCCGAAGGGTATAA
TCCCACCCAAGCCGAAGGAG

Downstream 100 bases:

>100_bases
AGGGCCCCGGGGGCTCCCGAAGGCGGCGGGGAAAGCGGACATGACCCCTCTGGAAGCTTTCCAGATCCTTGATCTGCGGG
TGGGGCGGGTCCTCCGGGCG

Product: phenylaceate-CoA ligase/coenzyme F390 synthetase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MDVDRLARFREVVAKAKAHPVYREKLRDVDPEKLTLKDLSSLPPTTREEWLAYLGENPKPPEGASLMHLTPSPVLGWMPE
YLSQEDLHYQAEALAAHYRRLGLVGKKVLVAFSYHVFAGGWLFHQALWRAGNLVFPHGPGEAKRVAELGERYGFDVLVTN
PSFALKVAQAGGRFPLLLAGGEPFTSVPGFRERVEEALGGVALDAYGTSELGIVAGERPEKDGLWEIPEMAVLEVLDPET
LRPVADGEKGELVVTALSRTLMPMVRFRTGDLAVAERREGLTVLPRGVFGRTDQMVKVKGVKLYPTELAPVLAGFGLDPK
GFQVVVERKLEGTDKLVLRLKAEKVPPGLFEAIQKATGLKVDEVELVETLEGGLLVDRRF

Sequences:

>Translated_380_residues
MDVDRLARFREVVAKAKAHPVYREKLRDVDPEKLTLKDLSSLPPTTREEWLAYLGENPKPPEGASLMHLTPSPVLGWMPE
YLSQEDLHYQAEALAAHYRRLGLVGKKVLVAFSYHVFAGGWLFHQALWRAGNLVFPHGPGEAKRVAELGERYGFDVLVTN
PSFALKVAQAGGRFPLLLAGGEPFTSVPGFRERVEEALGGVALDAYGTSELGIVAGERPEKDGLWEIPEMAVLEVLDPET
LRPVADGEKGELVVTALSRTLMPMVRFRTGDLAVAERREGLTVLPRGVFGRTDQMVKVKGVKLYPTELAPVLAGFGLDPK
GFQVVVERKLEGTDKLVLRLKAEKVPPGLFEAIQKATGLKVDEVELVETLEGGLLVDRRF
>Mature_380_residues
MDVDRLARFREVVAKAKAHPVYREKLRDVDPEKLTLKDLSSLPPTTREEWLAYLGENPKPPEGASLMHLTPSPVLGWMPE
YLSQEDLHYQAEALAAHYRRLGLVGKKVLVAFSYHVFAGGWLFHQALWRAGNLVFPHGPGEAKRVAELGERYGFDVLVTN
PSFALKVAQAGGRFPLLLAGGEPFTSVPGFRERVEEALGGVALDAYGTSELGIVAGERPEKDGLWEIPEMAVLEVLDPET
LRPVADGEKGELVVTALSRTLMPMVRFRTGDLAVAERREGLTVLPRGVFGRTDQMVKVKGVKLYPTELAPVLAGFGLDPK
GFQVVVERKLEGTDKLVLRLKAEKVPPGLFEAIQKATGLKVDEVELVETLEGGLLVDRRF

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=342, Percent_Identity=28.3625730994152, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 41859; Mature: 41859

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVDRLARFREVVAKAKAHPVYREKLRDVDPEKLTLKDLSSLPPTTREEWLAYLGENPKP
CCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEHHHHHCCCCCCHHHHHHHHCCCCCC
PEGASLMHLTPSPVLGWMPEYLSQEDLHYQAEALAAHYRRLGLVGKKVLVAFSYHVFAGG
CCCCEEEEECCCCHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLFHQALWRAGNLVFPHGPGEAKRVAELGERYGFDVLVTNPSFALKVAQAGGRFPLLLAG
HHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEEC
GEPFTSVPGFRERVEEALGGVALDAYGTSELGIVAGERPEKDGLWEIPEMAVLEVLDPET
CCCCCCCCCHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCHH
LRPVADGEKGELVVTALSRTLMPMVRFRTGDLAVAERREGLTVLPRGVFGRTDQMVKVKG
CCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEECCCCCCCCCCEEEEEC
VKLYPTELAPVLAGFGLDPKGFQVVVERKLEGTDKLVLRLKAEKVPPGLFEAIQKATGLK
EEECCHHHHHHHHCCCCCCCCCEEEEEHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
VDEVELVETLEGGLLVDRRF
CHHHHHHHHHCCCEEEECCC
>Mature Secondary Structure
MDVDRLARFREVVAKAKAHPVYREKLRDVDPEKLTLKDLSSLPPTTREEWLAYLGENPKP
CCHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEHHHHHCCCCCCHHHHHHHHCCCCCC
PEGASLMHLTPSPVLGWMPEYLSQEDLHYQAEALAAHYRRLGLVGKKVLVAFSYHVFAGG
CCCCEEEEECCCCHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLFHQALWRAGNLVFPHGPGEAKRVAELGERYGFDVLVTNPSFALKVAQAGGRFPLLLAG
HHHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCCEEEEEEC
GEPFTSVPGFRERVEEALGGVALDAYGTSELGIVAGERPEKDGLWEIPEMAVLEVLDPET
CCCCCCCCCHHHHHHHHHCCEEEECCCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCHH
LRPVADGEKGELVVTALSRTLMPMVRFRTGDLAVAERREGLTVLPRGVFGRTDQMVKVKG
CCCCCCCCCCCEEHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEECCCCCCCCCCEEEEEC
VKLYPTELAPVLAGFGLDPKGFQVVVERKLEGTDKLVLRLKAEKVPPGLFEAIQKATGLK
EEECCHHHHHHHHCCCCCCCCCEEEEEHHCCCCCEEEEEEECCCCCCHHHHHHHHHHCCC
VDEVELVETLEGGLLVDRRF
CHHHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]