Click here to switch to the map view.

The map label for this gene is ttuD [H]

Identifier: 55980469

GI number: 55980469

Start: 464959

End: 466179

Strand: Reverse

Name: ttuD [H]

Synonym: TTHA0500

Alternate gene names: 55980469

Gene position: 466179-464959 (Counterclockwise)

Preceding gene: 55980470

Following gene: 55980468

Centisome position: 25.2

GC content: 70.68

Gene sequence:

>1221_bases
GTGGAAGCCCTCCTGAAGGAAGCCTTCCTCGAGGCCCTGAAGGCCACGGACCCCTACCGCCTCACGGCAAAACACCTCCC
CCCTTGGCGGCCGGACCTCGTCCTGGCGGTGGGGAAGGCGGCGGCCCCCATGCTCCAGGCCGCCCTGGACCGCTACGGAG
AGGTCCCCTACCACCTCACCCTGCCCAAGGGGCAAAAGGCCCCTGGGCTCAAGGCGGTCTTCGCCCGCCACCCCGTCCCC
GACGAGGAGAGCGTCCGGGCGGCCGAGGAGGTCCTCGGCCTCCTCCAGGGCCTTTCCCCGAGGGCACGGGTCTTGGCCCT
CCTCTCGGGCGGGGGAAGCGCCCTGTGGTGCGCCCCTTTGGGGATCTCCCTGGAGGAGAAGCGGGCCCTCACCGAGGCCC
TCCTCAAAAGCGGGGCGAGCATCCACGAGATGAACGCCGTGCGCAAGCACCTCTCCCAGATCAAAGGGGGAAGAGCCCTC
CTCGCCACCAGGGCGAAGGTCCACGTCCTCCTCCTCTCCGACGTGCCGGGGGACGACCCCTCGGTCATCGCCTCGGGCCC
CTTCCACCCGGACCCCACCACCTACGCCGAGGCCCTCGCCCTGTTGGACCGCTACGGCCTCGCCTTCCCCGGGGCCCGGG
CCGTCCTCCGGCAGGGGGTGGAAGGGCGCCTCCCCGAGACCCTAAAGCCCCAAGACCCCGCCCTAAGGCGCCTCGCCTGG
CGCCTCGTGGGGACGAACCTCCACCTCCTCCGGGCGGCGCAAAGGTTCTTGCGGGCCCGGGGTTTCCGGGCGGCGGTCCT
CTCCGACCGCTTCGGGGGGGAGGCGAGGGCCCTCGCCCGCTTCCACGCCGAGCTCATAGAGGCCATCCGCGCCCACGGGG
TGCCTTTTAGGAAGCCCCTCTTCCTCCTCTCCGGAGGGGAGGCCCAGGTGCGGGTGGTGGGAAGGGGAAGGGGCGGGCGG
AACCTGGAGTTCCTCCTCGCCCTCTACGCCCACCTCAAAACCCCCCTCTACGCCCTCGCCGCAGACTCCGACGGCCTGGA
CGGAAATAGCGGCGCCGCCGGGGCCCTCCTCACCCCGGCGGTGTGGGAAAAGGGCCTAGACCCCAGGCCCTTCCTGGAGG
AAAACGACAGCCTCGGCTTCTTCCAGGAGGCGGGAACCCTTCTTAAAACCGGCCCCACGGGGACCAACCTCAACGACTTC
CGCCTCCTCCTTGTAGACTGA

Upstream 100 bases:

>100_bases
CCGGGCTCAACTTTGGGGACTGCCTGAGCTACGCCCTGGCCCGGGTGGAGGGGGAACCCCTCCTCTACAAGGGCCAGGGC
TTTGACCGGACGGACCTGGC

Downstream 100 bases:

>100_bases
GGGGGTGGAGTACCCGGAGCTTGCCCCGGTCCTCGAGGCCATCCTCAAGACCGTCCCGGCGCAAAAGGTCATCCTCTTCG
GCAGCCGGGCGCGGGGGGAA

Product: glycerate dehydrogenase/hydroxypyruvate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MEALLKEAFLEALKATDPYRLTAKHLPPWRPDLVLAVGKAAAPMLQAALDRYGEVPYHLTLPKGQKAPGLKAVFARHPVP
DEESVRAAEEVLGLLQGLSPRARVLALLSGGGSALWCAPLGISLEEKRALTEALLKSGASIHEMNAVRKHLSQIKGGRAL
LATRAKVHVLLLSDVPGDDPSVIASGPFHPDPTTYAEALALLDRYGLAFPGARAVLRQGVEGRLPETLKPQDPALRRLAW
RLVGTNLHLLRAAQRFLRARGFRAAVLSDRFGGEARALARFHAELIEAIRAHGVPFRKPLFLLSGGEAQVRVVGRGRGGR
NLEFLLALYAHLKTPLYALAADSDGLDGNSGAAGALLTPAVWEKGLDPRPFLEENDSLGFFQEAGTLLKTGPTGTNLNDF
RLLLVD

Sequences:

>Translated_406_residues
MEALLKEAFLEALKATDPYRLTAKHLPPWRPDLVLAVGKAAAPMLQAALDRYGEVPYHLTLPKGQKAPGLKAVFARHPVP
DEESVRAAEEVLGLLQGLSPRARVLALLSGGGSALWCAPLGISLEEKRALTEALLKSGASIHEMNAVRKHLSQIKGGRAL
LATRAKVHVLLLSDVPGDDPSVIASGPFHPDPTTYAEALALLDRYGLAFPGARAVLRQGVEGRLPETLKPQDPALRRLAW
RLVGTNLHLLRAAQRFLRARGFRAAVLSDRFGGEARALARFHAELIEAIRAHGVPFRKPLFLLSGGEAQVRVVGRGRGGR
NLEFLLALYAHLKTPLYALAADSDGLDGNSGAAGALLTPAVWEKGLDPRPFLEENDSLGFFQEAGTLLKTGPTGTNLNDF
RLLLVD
>Mature_406_residues
MEALLKEAFLEALKATDPYRLTAKHLPPWRPDLVLAVGKAAAPMLQAALDRYGEVPYHLTLPKGQKAPGLKAVFARHPVP
DEESVRAAEEVLGLLQGLSPRARVLALLSGGGSALWCAPLGISLEEKRALTEALLKSGASIHEMNAVRKHLSQIKGGRAL
LATRAKVHVLLLSDVPGDDPSVIASGPFHPDPTTYAEALALLDRYGLAFPGARAVLRQGVEGRLPETLKPQDPALRRLAW
RLVGTNLHLLRAAQRFLRARGFRAAVLSDRFGGEARALARFHAELIEAIRAHGVPFRKPLFLLSGGEAQVRVVGRGRGGR
NLEFLLALYAHLKTPLYALAADSDGLDGNSGAAGALLTPAVWEKGLDPRPFLEENDSLGFFQEAGTLLKTGPTGTNLNDF
RLLLVD

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=443, Percent_Identity=34.9887133182844, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI193205461, Length=415, Percent_Identity=30.3614457831325, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI19920578, Length=399, Percent_Identity=32.0802005012531, Blast_Score=124, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 43700; Mature: 43700

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALLKEAFLEALKATDPYRLTAKHLPPWRPDLVLAVGKAAAPMLQAALDRYGEVPYHLT
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEE
LPKGQKAPGLKAVFARHPVPDEESVRAAEEVLGLLQGLSPRARVLALLSGGGSALWCAPL
CCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCEEEEEEC
GISLEEKRALTEALLKSGASIHEMNAVRKHLSQIKGGRALLATRAKVHVLLLSDVPGDDP
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEECCCCCCC
SVIASGPFHPDPTTYAEALALLDRYGLAFPGARAVLRQGVEGRLPETLKPQDPALRRLAW
CEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
RLVGTNLHLLRAAQRFLRARGFRAAVLSDRFGGEARALARFHAELIEAIRAHGVPFRKPL
HHHCCCHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
FLLSGGEAQVRVVGRGRGGRNLEFLLALYAHLKTPLYALAADSDGLDGNSGAAGALLTPA
EEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHH
VWEKGLDPRPFLEENDSLGFFQEAGTLLKTGPTGTNLNDFRLLLVD
HHHCCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MEALLKEAFLEALKATDPYRLTAKHLPPWRPDLVLAVGKAAAPMLQAALDRYGEVPYHLT
CHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCEEEE
LPKGQKAPGLKAVFARHPVPDEESVRAAEEVLGLLQGLSPRARVLALLSGGGSALWCAPL
CCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHEEEEEECCCCEEEEEEC
GISLEEKRALTEALLKSGASIHEMNAVRKHLSQIKGGRALLATRAKVHVLLLSDVPGDDP
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCEEEEEEEECCCCCCC
SVIASGPFHPDPTTYAEALALLDRYGLAFPGARAVLRQGVEGRLPETLKPQDPALRRLAW
CEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
RLVGTNLHLLRAAQRFLRARGFRAAVLSDRFGGEARALARFHAELIEAIRAHGVPFRKPL
HHHCCCHHHHHHHHHHHHHCCCCEEHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCE
FLLSGGEAQVRVVGRGRGGRNLEFLLALYAHLKTPLYALAADSDGLDGNSGAAGALLTPA
EEEECCCEEEEEEECCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCHH
VWEKGLDPRPFLEENDSLGFFQEAGTLLKTGPTGTNLNDFRLLLVD
HHHCCCCCCCCCCCCCCCCHHHHCCCEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]