Click here to switch to the map view.

The map label for this gene is lysN [H]

Identifier: 55980380

GI number: 55980380

Start: 389901

End: 391094

Strand: Reverse

Name: lysN [H]

Synonym: TTHA0411

Alternate gene names: 55980380

Gene position: 391094-389901 (Counterclockwise)

Preceding gene: 55980381

Following gene: 55980375

Centisome position: 21.14

GC content: 69.26

Gene sequence:

>1194_bases
GTGAAACCGCTAAGCTGGTCCGAGGCGTTCGGTAAAAGCGCGGGAAGGATCCAGGCCTCCACCATCCGGGAGCTTCTCAA
GCTCACCCAGCGCCCCGGCATCCTGAGCTTCGCCGGGGGGCTCCCGGCCCCCGAGCTCTTCCCCAAGGAGGAGGCGGCGG
AGGCCGCGGCGCGGATCCTGCGGGAGAAGGGCGAGGTCGCCCTCCAGTACAGCCCCACCGAGGGCTACGCCCCCCTAAGG
GCCTTCGTGGCGGAGTGGATCGGCGTGCGCCCCGAGGAGGTCCTCATCACCACCGGGAGCCAGCAGGCCTTGGACCTCGT
GGGCAAGGTCTTCCTGGACGAGGGAAGCCCCGTGCTGCTGGAGGCCCCAAGCTACATGGGGGCCATCCAGGCCTTCCGCC
TCCAGGGCCCCCGCTTCCTCACGGTGCCCGCCGGGGAGGAGGGCCCGGACCTGGACGCCCTGGAAGAGGTCCTCAAAAGG
GAGCGCCCCCGCTTCCTCTACCTCATCCCCTCTTTCCAGAACCCCACGGGGGGCCTCACGCCCCTTCCCGCCCGGAAGCG
GCTCTTGCAGATGGTGATGGAGCGGGGCCTCGTGGTGGTGGAGGACGACGCCTACCGGGAGCTCTACTTCGGGGAGGCGC
GCCTCCCGAGCCTCTTTGAGCTCGCCCGGGAGGCGGGCTACCCCGGGGTCATCTACCTGGGAAGCTTCTCCAAGGTCCTC
TCCCCCGGGCTTCGCGTGGCCTTCGCCGTGGCCCACCCGGAGGCCCTGCAGAAGCTCGTCCAGGCCAAACAGGGGGCCGA
CCTCCACACCCCCATGCTCAACCAGATGCTGGTCCACGAGCTCTTAAAGGAGGGCTTCTCCGAGCGCTTGGAACGGGTCC
GCAGGGTCTACCGGGAAAAGGCCCAGGCCATGCTCCATGCCCTGGACCGGGAGGTGCCCAAGGAGGTGCGCTACACAAGG
CCCAAGGGCGGGATGTTCGTCTGGATGGAGCTCCCCAAGGGCCTCTCCGCCGAGGGCCTCTTCCGGAGGGCCCTCGAGGA
GAACGTGGCCTTCGTGCCGGGAGGTCCTTTCTTCGCCAACGGGGGCGGGGAGAACACCCTGAGGCTCTCCTACGCCACCC
TGGACCGGGAGGGGATCGCGGAGGGCGTGCGGCGGCTGGGGCGGGCGCTAAAGGGGCTTTTGGCCTTGGTCTAG

Upstream 100 bases:

>100_bases
CCTAAGGGCCCGCACCCCCCGCCAAGGCCGTGGGCAGGCGCTTTCGGAGCTCCGGGAGCGCGTTCCGGCGGGAGGAAGGG
AAGCGGGGTAGACTATAGGG

Downstream 100 bases:

>100_bases
GAAGAGGAGGGGCTCTCTCCTTCTCAGCTCCCTCACCAGGGCGTCTAAAAAGGCTTCACCCTCCGCCACCGCCTCCTCGG
GCCTCAGCAAAAGGGGTGCC

Product: alpha-aminoadipate aminotransferase

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 397; Mature: 397

Protein sequence:

>397_residues
MKPLSWSEAFGKSAGRIQASTIRELLKLTQRPGILSFAGGLPAPELFPKEEAAEAAARILREKGEVALQYSPTEGYAPLR
AFVAEWIGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSYMGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKR
ERPRFLYLIPSFQNPTGGLTPLPARKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFSKVL
SPGLRVAFAVAHPEALQKLVQAKQGADLHTPMLNQMLVHELLKEGFSERLERVRRVYREKAQAMLHALDREVPKEVRYTR
PKGGMFVWMELPKGLSAEGLFRRALEENVAFVPGGPFFANGGGENTLRLSYATLDREGIAEGVRRLGRALKGLLALV

Sequences:

>Translated_397_residues
MKPLSWSEAFGKSAGRIQASTIRELLKLTQRPGILSFAGGLPAPELFPKEEAAEAAARILREKGEVALQYSPTEGYAPLR
AFVAEWIGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSYMGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKR
ERPRFLYLIPSFQNPTGGLTPLPARKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFSKVL
SPGLRVAFAVAHPEALQKLVQAKQGADLHTPMLNQMLVHELLKEGFSERLERVRRVYREKAQAMLHALDREVPKEVRYTR
PKGGMFVWMELPKGLSAEGLFRRALEENVAFVPGGPFFANGGGENTLRLSYATLDREGIAEGVRRLGRALKGLLALV
>Mature_397_residues
MKPLSWSEAFGKSAGRIQASTIRELLKLTQRPGILSFAGGLPAPELFPKEEAAEAAARILREKGEVALQYSPTEGYAPLR
AFVAEWIGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLLEAPSYMGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKR
ERPRFLYLIPSFQNPTGGLTPLPARKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFSKVL
SPGLRVAFAVAHPEALQKLVQAKQGADLHTPMLNQMLVHELLKEGFSERLERVRRVYREKAQAMLHALDREVPKEVRYTR
PKGGMFVWMELPKGLSAEGLFRRALEENVAFVPGGPFFANGGGENTLRLSYATLDREGIAEGVRRLGRALKGLLALV

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=422, Percent_Identity=27.9620853080569, Blast_Score=165, Evalue=8e-41,
Organism=Homo sapiens, GI33469970, Length=422, Percent_Identity=27.9620853080569, Blast_Score=165, Evalue=8e-41,
Organism=Escherichia coli, GI1787710, Length=382, Percent_Identity=30.3664921465969, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1790797, Length=383, Percent_Identity=25.8485639686684, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1788722, Length=340, Percent_Identity=23.8235294117647, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788332, Length=234, Percent_Identity=27.7777777777778, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6321000, Length=430, Percent_Identity=24.6511627906977, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321929, Length=469, Percent_Identity=23.6673773987207, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21356535, Length=399, Percent_Identity=27.3182957393484, Blast_Score=139, Evalue=4e-33,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 43876; Mature: 43876

Theoretical pI: Translated: 9.07; Mature: 9.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLSWSEAFGKSAGRIQASTIRELLKLTQRPGILSFAGGLPAPELFPKEEAAEAAARIL
CCCCCHHHHHCCCCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
REKGEVALQYSPTEGYAPLRAFVAEWIGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLL
HHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
EAPSYMGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKRERPRFLYLIPSFQNPTGGLT
ECCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
PLPARKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFSKVL
CCHHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCHHHH
SPGLRVAFAVAHPEALQKLVQAKQGADLHTPMLNQMLVHELLKEGFSERLERVRRVYREK
CCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAMLHALDREVPKEVRYTRPKGGMFVWMELPKGLSAEGLFRRALEENVAFVPGGPFFAN
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCCEEEC
GGGENTLRLSYATLDREGIAEGVRRLGRALKGLLALV
CCCCCEEEEEEEHHCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKPLSWSEAFGKSAGRIQASTIRELLKLTQRPGILSFAGGLPAPELFPKEEAAEAAARIL
CCCCCHHHHHCCCCCCEEHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCHHHHHHHHHHH
REKGEVALQYSPTEGYAPLRAFVAEWIGVRPEEVLITTGSQQALDLVGKVFLDEGSPVLL
HHCCCEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEE
EAPSYMGAIQAFRLQGPRFLTVPAGEEGPDLDALEEVLKRERPRFLYLIPSFQNPTGGLT
ECCHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCC
PLPARKRLLQMVMERGLVVVEDDAYRELYFGEARLPSLFELAREAGYPGVIYLGSFSKVL
CCHHHHHHHHHHHHCCCEEEECCCHHHHHCCCCCCCHHHHHHHHCCCCCEEEECCCHHHH
SPGLRVAFAVAHPEALQKLVQAKQGADLHTPMLNQMLVHELLKEGFSERLERVRRVYREK
CCCCEEEEEECCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQAMLHALDREVPKEVRYTRPKGGMFVWMELPKGLSAEGLFRRALEENVAFVPGGPFFAN
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCEECCCCCEEEC
GGGENTLRLSYATLDREGIAEGVRRLGRALKGLLALV
CCCCCEEEEEEEHHCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA