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The map label for this gene is slyD [H]

Identifier: 55980315

GI number: 55980315

Start: 327520

End: 327969

Strand: Reverse

Name: slyD [H]

Synonym: TTHA0346

Alternate gene names: 55980315

Gene position: 327969-327520 (Counterclockwise)

Preceding gene: 55980318

Following gene: 55980314

Centisome position: 17.73

GC content: 68.44

Gene sequence:

>450_bases
ATGAAGGTTGGACAGGACAAGGTTGTGACCATCCGCTACACCCTCCAGGTGGAGGGTGAGGTTCTGGACCAGGGGGAGCT
TTCCTACCTCCACGGCCACCGCAACCTCATCCCGGGCCTCGAGGAGGCCCTGGAGGGCCGGGAGGAGGGGGAGGCTTTCC
AGGCCCACGTCCCCGCCGAGAAGGCCTACGGCCCCCACGACCCCGAGGGGGTCCAGGTGGTGCCCCTCTCCGCCTTCCCC
GAGGACGCCGAGGTGGTTCCCGGGGCCCAGTTCTACGCCCAGGACATGGAGGGGAACCCCATGCCCCTCACCGTGGTGGC
GGTGGAAGGGGAGGAGGTGACCGTGGACTTCAACCACCCCCTGGCGGGCAAGGACCTGGACTTCCAGGTGGAGGTGGTGA
AGGTCCGCGAGGCCACCCCCGAGGAACTCCTGCACGGCCACGCCCACTAA

Upstream 100 bases:

>100_bases
TATAGCCCTTGGGAAGGGGTTCGGAGGGGTGGGGGTTCCCTCTTGGGCCGAGGTCTGCTACCCTAGGAGGAGCAAGCAAG
GCTTGCGAAAGGAACGTGCA

Downstream 100 bases:

>100_bases
GGGCGCAGAAAGGGCAGGGCCCCGGCCTTCGCCGGGGCTTTTGTAGTATGGGGTGGTATGCGCGTCGTCGTGGTGGGAAC
CCGGGGGAGCGCCCTGGCCC

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MKVGQDKVVTIRYTLQVEGEVLDQGELSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAEKAYGPHDPEGVQVVPLSAFP
EDAEVVPGAQFYAQDMEGNPMPLTVVAVEGEEVTVDFNHPLAGKDLDFQVEVVKVREATPEELLHGHAH

Sequences:

>Translated_149_residues
MKVGQDKVVTIRYTLQVEGEVLDQGELSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAEKAYGPHDPEGVQVVPLSAFP
EDAEVVPGAQFYAQDMEGNPMPLTVVAVEGEEVTVDFNHPLAGKDLDFQVEVVKVREATPEELLHGHAH
>Mature_149_residues
MKVGQDKVVTIRYTLQVEGEVLDQGELSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAEKAYGPHDPEGVQVVPLSAFP
EDAEVVPGAQFYAQDMEGNPMPLTVVAVEGEEVTVDFNHPLAGKDLDFQVEVVKVREATPEELLHGHAH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=148, Percent_Identity=47.2972972972973, Blast_Score=113, Evalue=5e-27,
Organism=Escherichia coli, GI1786211, Length=143, Percent_Identity=27.972027972028, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16313; Mature: 16313

Theoretical pI: Translated: 4.21; Mature: 4.21

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVGQDKVVTIRYTLQVEGEVLDQGELSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAE
CCCCCCCEEEEEEEEEECCEEECCCCEEEECCCCCCCCCHHHHHCCCCCCCEEEEECCHH
KAYGPHDPEGVQVVPLSAFPEDAEVVPGAQFYAQDMEGNPMPLTVVAVEGEEVTVDFNHP
HCCCCCCCCCEEEEECCCCCCCCCCCCCHHHEEECCCCCCCCEEEEEECCCEEEEECCCC
LAGKDLDFQVEVVKVREATPEELLHGHAH
CCCCCCCEEEEEEEECCCCHHHHHCCCCC
>Mature Secondary Structure
MKVGQDKVVTIRYTLQVEGEVLDQGELSYLHGHRNLIPGLEEALEGREEGEAFQAHVPAE
CCCCCCCEEEEEEEEEECCEEECCCCEEEECCCCCCCCCHHHHHCCCCCCCEEEEECCHH
KAYGPHDPEGVQVVPLSAFPEDAEVVPGAQFYAQDMEGNPMPLTVVAVEGEEVTVDFNHP
HCCCCCCCCCEEEEECCCCCCCCCCCCCHHHEEECCCCCCCCEEEEEECCCEEEEECCCC
LAGKDLDFQVEVVKVREATPEELLHGHAH
CCCCCCCEEEEEEEECCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]