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The map label for this gene is hisK [H]

Identifier: 55980300

GI number: 55980300

Start: 316844

End: 317647

Strand: Direct

Name: hisK [H]

Synonym: TTHA0331

Alternate gene names: 55980300

Gene position: 316844-317647 (Clockwise)

Preceding gene: 55980299

Following gene: 55980305

Centisome position: 17.13

GC content: 69.78

Gene sequence:

>804_bases
ATGGTGGATAGCCACGTCCACACTCCCCTCTGCGGCCACGCGGAGGGCCACCCCGAGGCCTACCTGGAGGAGGCGCGGGC
CAAGGGGCTTAAAGGCGTGGTCTTCACCGACCACAGCCCCATGCCCCCCTGGTACGACCCGGAAAGCCGGATGCGCCTCG
AGGCCCTCCCCTTCTACCTCCTCGCCCTGGAAAGGGTGCGGGAACGGGCCCAGGACCTCTACGTGGGCATCGGCCTCGAG
GCGGACTTCCACCCCGGCACCGAGGGCTTCTTGGCCCAGCTCTTGCGCCGCTACCCCTTTGACTACGTCATCGGGAGCGT
CCACTACCTGGGGGCCTGGCCCCTGGACCACCCGGACCACCAGGAGGAGTACGCCTGGCGCGACCTCAAGGAGGTCTTCC
GGGCCTACTTTCAGGAGGTGGAGAAGGCGGCCCGAAGCGGCCTCTTCCACGCCATCGGCCACCTGGACCTCCCCAAGAAG
TTCGGCCACCGCCTCCCCGAGGAGGCCCTTTTGGAGCTCGCCGAGCCCGCCCTAAGGGCCGTCGCCGAGGCGGGGCTCTT
CCTGGACGTGAACACCGCCGGCCTGAGGAGGCCGGCGAAGGAGGTCTACCCCGCCCCCGCCCTCCTCAGGAGGGCCCGGG
AGCTCGGCATCGGGCTCGTCCTCGGCTCCGACGCCCACCGCCCGGAGGAGGTGGGCTTCGCCTTCCCCGAGGTCCAAGCC
CTCCTCGCCGGGCTCGGTTTTCGGGAAGCCTACTACTTCGTGGAAGGAAGCCCCGTGGCCTACCCCTTGTCCAGGGCCTC
GTAG

Upstream 100 bases:

>100_bases
GCGGAGGACCCCTTCCTCTCCCTGGACCTCTCCCGGGCCCTGGGACGGGAGGTGGTGGCCTACGCCTGGGCGGGGAAGCT
CGTGCGGGTAGAATCCCCCC

Downstream 100 bases:

>100_bases
ACCCGTTTCCGCTCCCGGCCCAGGTCCAGGTCCTCCCGGCTTCCCCCCGCCGCCTCGTAGGCCCGCACCGCCTCCACGAG
GCGCAGGAAGGCCTCGGCGC

Product: histidinol-phosphatase

Products: NA

Alternate protein names: HolPase [H]

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MVDSHVHTPLCGHAEGHPEAYLEEARAKGLKGVVFTDHSPMPPWYDPESRMRLEALPFYLLALERVRERAQDLYVGIGLE
ADFHPGTEGFLAQLLRRYPFDYVIGSVHYLGAWPLDHPDHQEEYAWRDLKEVFRAYFQEVEKAARSGLFHAIGHLDLPKK
FGHRLPEEALLELAEPALRAVAEAGLFLDVNTAGLRRPAKEVYPAPALLRRARELGIGLVLGSDAHRPEEVGFAFPEVQA
LLAGLGFREAYYFVEGSPVAYPLSRAS

Sequences:

>Translated_267_residues
MVDSHVHTPLCGHAEGHPEAYLEEARAKGLKGVVFTDHSPMPPWYDPESRMRLEALPFYLLALERVRERAQDLYVGIGLE
ADFHPGTEGFLAQLLRRYPFDYVIGSVHYLGAWPLDHPDHQEEYAWRDLKEVFRAYFQEVEKAARSGLFHAIGHLDLPKK
FGHRLPEEALLELAEPALRAVAEAGLFLDVNTAGLRRPAKEVYPAPALLRRARELGIGLVLGSDAHRPEEVGFAFPEVQA
LLAGLGFREAYYFVEGSPVAYPLSRAS
>Mature_267_residues
MVDSHVHTPLCGHAEGHPEAYLEEARAKGLKGVVFTDHSPMPPWYDPESRMRLEALPFYLLALERVRERAQDLYVGIGLE
ADFHPGTEGFLAQLLRRYPFDYVIGSVHYLGAWPLDHPDHQEEYAWRDLKEVFRAYFQEVEKAARSGLFHAIGHLDLPKK
FGHRLPEEALLELAEPALRAVAEAGLFLDVNTAGLRRPAKEVYPAPALLRRARELGIGLVLGSDAHRPEEVGFAFPEVQA
LLAGLGFREAYYFVEGSPVAYPLSRAS

Specific function: Unknown

COG id: COG1387

COG function: function code ER; Histidinol phosphatase and related hydrolases of the PHP family

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PHP hydrolase family. HisK subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010140
- InterPro:   IPR004013
- InterPro:   IPR016195 [H]

Pfam domain/function: PF02811 PHP [H]

EC number: =3.1.3.15 [H]

Molecular weight: Translated: 29976; Mature: 29976

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDSHVHTPLCGHAEGHPEAYLEEARAKGLKGVVFTDHSPMPPWYDPESRMRLEALPFYL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LALERVRERAQDLYVGIGLEADFHPGTEGFLAQLLRRYPFDYVIGSVHYLGAWPLDHPDH
HHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCC
QEEYAWRDLKEVFRAYFQEVEKAARSGLFHAIGHLDLPKKFGHRLPEEALLELAEPALRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHH
VAEAGLFLDVNTAGLRRPAKEVYPAPALLRRARELGIGLVLGSDAHRPEEVGFAFPEVQA
HHHCCCEEEECHHHHCCCHHHHCCCHHHHHHHHHCCEEEEECCCCCCHHHHCCCCHHHHH
LLAGLGFREAYYFVEGSPVAYPLSRAS
HHHHCCHHHEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MVDSHVHTPLCGHAEGHPEAYLEEARAKGLKGVVFTDHSPMPPWYDPESRMRLEALPFYL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
LALERVRERAQDLYVGIGLEADFHPGTEGFLAQLLRRYPFDYVIGSVHYLGAWPLDHPDH
HHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHEECCCCCCCCC
QEEYAWRDLKEVFRAYFQEVEKAARSGLFHAIGHLDLPKKFGHRLPEEALLELAEPALRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHH
VAEAGLFLDVNTAGLRRPAKEVYPAPALLRRARELGIGLVLGSDAHRPEEVGFAFPEVQA
HHHCCCEEEECHHHHCCCHHHHCCCHHHHHHHHHCCEEEEECCCCCCHHHHCCCCHHHHH
LLAGLGFREAYYFVEGSPVAYPLSRAS
HHHHCCHHHEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]