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The map label for this gene is ctaC [H]

Identifier: 55980280

GI number: 55980280

Start: 298729

End: 299742

Strand: Direct

Name: ctaC [H]

Synonym: TTHA0311

Alternate gene names: 55980280

Gene position: 298729-299742 (Clockwise)

Preceding gene: 55980279

Following gene: 55980281

Centisome position: 16.15

GC content: 67.06

Gene sequence:

>1014_bases
ATGCAGAGAAGCTTCGCGGCGCTAGGTCTTTGGGGTCTGTCCCTGGCCCAGGAGGCCCACCGGGTGGCCATCACCCACCC
GGGCGGCTCCTTCAACCAGGAGGTGGCCTTCCTCTTCCCTTGGGTCTACTTCTTCTCCTTCCTGATCTTCCTGGTGGTGG
CCGGGTCCTTGGCGTACGTCACCTGGAAGTTCCGGGCAAGGCCCGAGGACCAGGAGGAACCTCCCCAGATCCACGGGAAC
GACCGCCTCGAGGTGGTCTGGACCCTGATCCCCCTGGCCATCGTCTTCGTCCTCTTCGGCCTCACGGCCAAGGCCCTCAT
CCAGGTGAACCGGCCCATCCCTGGGGCCATGAAGGTGGAGGTCACCGGGTATCAGTTCTGGTGGGACTTCCACTACCCCG
AGCTCGGCCTGCGCAACTCCAACGAGCTCGTCCTCCCCGCCGGGGTACCCGTGGAGCTGGAGATCACCTCCAAGGACGTG
ATCCACTCCTTCTGGGTGCCGGGCCTCGCCGGGAAGCGGGACGCCATTCCGGGACAAACGACCCGGATCTCCTTTGAACC
CAAGGAGCCCGGCCTCTACTACGGCTTCTGCGCCGAGCTCTGCGGGGCGAGCCACGCCCGCATGCTCTTCCGCGTCGTGG
TCCTCCCCAAGGAGGAGTTTGACCGCTTCGTGGAGGCGGCCAAAGCCTCCCCGGCCCCCGTGGCCGATGAGCGGGGCCAG
CAGGTCTTCCAGCAGAACTGCGCCGCCTGCCACGGCGTGGCCCGGAGCATGCCCCCCGCGGTCATCGGGCCCGAGCTTGG
GCTTTGGGGCAACCGCACGAGCCTGGGGGCGGGCATCGTGGAGAACACCCCGGAAAACCTCAAGGCCTGGATCCGCGACC
CCGCGGGGATGAAGCCCGGGGTGAAGATGCCCGGCTTCCCCCAGCTCTCCGAGGAGGACCTGGACGCTCTGGTGCGCTAC
CTGGAGGGGCTCAAGGTGGAGGGGTTTGACTTCGGGGCCCTGCCCAAGTTCTAA

Upstream 100 bases:

>100_bases
GGAGAACCGCGGTTTCCCTGTATAAATACTCCATGCTCTACCTGGCCCTGCTCTTCGCGGCCATGGCGGTAGACCGGGCA
GTGTAAAGGGAGGTAACGGG

Downstream 100 bases:

>100_bases
GGGAGGTGCGGGATGGCGATCACGGCAAAGCCGAAAGCGGGCGTTTGGGCGGTCCTTTGGGACCTGCTCACTACGGTGGA
CCACAAGAAGATCGGCCTCA

Product: cytochrome Caa3 oxidase subunit IIC

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MQRSFAALGLWGLSLAQEAHRVAITHPGGSFNQEVAFLFPWVYFFSFLIFLVVAGSLAYVTWKFRARPEDQEEPPQIHGN
DRLEVVWTLIPLAIVFVLFGLTAKALIQVNRPIPGAMKVEVTGYQFWWDFHYPELGLRNSNELVLPAGVPVELEITSKDV
IHSFWVPGLAGKRDAIPGQTTRISFEPKEPGLYYGFCAELCGASHARMLFRVVVLPKEEFDRFVEAAKASPAPVADERGQ
QVFQQNCAACHGVARSMPPAVIGPELGLWGNRTSLGAGIVENTPENLKAWIRDPAGMKPGVKMPGFPQLSEEDLDALVRY
LEGLKVEGFDFGALPKF

Sequences:

>Translated_337_residues
MQRSFAALGLWGLSLAQEAHRVAITHPGGSFNQEVAFLFPWVYFFSFLIFLVVAGSLAYVTWKFRARPEDQEEPPQIHGN
DRLEVVWTLIPLAIVFVLFGLTAKALIQVNRPIPGAMKVEVTGYQFWWDFHYPELGLRNSNELVLPAGVPVELEITSKDV
IHSFWVPGLAGKRDAIPGQTTRISFEPKEPGLYYGFCAELCGASHARMLFRVVVLPKEEFDRFVEAAKASPAPVADERGQ
QVFQQNCAACHGVARSMPPAVIGPELGLWGNRTSLGAGIVENTPENLKAWIRDPAGMKPGVKMPGFPQLSEEDLDALVRY
LEGLKVEGFDFGALPKF
>Mature_337_residues
MQRSFAALGLWGLSLAQEAHRVAITHPGGSFNQEVAFLFPWVYFFSFLIFLVVAGSLAYVTWKFRARPEDQEEPPQIHGN
DRLEVVWTLIPLAIVFVLFGLTAKALIQVNRPIPGAMKVEVTGYQFWWDFHYPELGLRNSNELVLPAGVPVELEITSKDV
IHSFWVPGLAGKRDAIPGQTTRISFEPKEPGLYYGFCAELCGASHARMLFRVVVLPKEEFDRFVEAAKASPAPVADERGQ
QVFQQNCAACHGVARSMPPAVIGPELGLWGNRTSLGAGIVENTPENLKAWIRDPAGMKPGVKMPGFPQLSEEDLDALVRY
LEGLKVEGFDFGALPKF

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=170, Percent_Identity=32.9411764705882, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786635, Length=244, Percent_Identity=30.7377049180328, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6226540, Length=215, Percent_Identity=26.5116279069767, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM; PF00034 Cytochrom_C [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 37351; Mature: 37351

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSFAALGLWGLSLAQEAHRVAITHPGGSFNQEVAFLFPWVYFFSFLIFLVVAGSLAYV
CCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
TWKFRARPEDQEEPPQIHGNDRLEVVWTLIPLAIVFVLFGLTAKALIQVNRPIPGAMKVE
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEE
VTGYQFWWDFHYPELGLRNSNELVLPAGVPVELEITSKDVIHSFWVPGLAGKRDAIPGQT
EEEEEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCC
TRISFEPKEPGLYYGFCAELCGASHARMLFRVVVLPKEEFDRFVEAAKASPAPVADERGQ
EEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCHHHHH
QVFQQNCAACHGVARSMPPAVIGPELGLWGNRTSLGAGIVENTPENLKAWIRDPAGMKPG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHCCCCCCCCC
VKMPGFPQLSEEDLDALVRYLEGLKVEGFDFGALPKF
CCCCCCCCCCHHHHHHHHHHHHCCEECCCCCCCCCCC
>Mature Secondary Structure
MQRSFAALGLWGLSLAQEAHRVAITHPGGSFNQEVAFLFPWVYFFSFLIFLVVAGSLAYV
CCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEE
TWKFRARPEDQEEPPQIHGNDRLEVVWTLIPLAIVFVLFGLTAKALIQVNRPIPGAMKVE
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCEEEE
VTGYQFWWDFHYPELGLRNSNELVLPAGVPVELEITSKDVIHSFWVPGLAGKRDAIPGQT
EEEEEEEEEECCCCCCCCCCCCEEEECCCCEEEEECCHHHHHHHCCCCCCCCCCCCCCCC
TRISFEPKEPGLYYGFCAELCGASHARMLFRVVVLPKEEFDRFVEAAKASPAPVADERGQ
EEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHEECCHHHHHHHHHHHCCCCCCCCHHHHH
QVFQQNCAACHGVARSMPPAVIGPELGLWGNRTSLGAGIVENTPENLKAWIRDPAGMKPG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHHHHCCCCCCCCC
VKMPGFPQLSEEDLDALVRYLEGLKVEGFDFGALPKF
CCCCCCCCCCHHHHHHHHHHHHCCEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7678007 [H]