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The map label for this gene is nusG

Identifier: 55980217

GI number: 55980217

Start: 238005

End: 238559

Strand: Reverse

Name: nusG

Synonym: TTHA0248

Alternate gene names: 55980217

Gene position: 238559-238005 (Counterclockwise)

Preceding gene: 55980218

Following gene: 55980216

Centisome position: 12.9

GC content: 65.95

Gene sequence:

>555_bases
ATGAGCATAGAGTGGTACGCGGTCCACACCCTGGTGGGGCAGGAGGAGAAGGCCAAGGCCAACCTGGAGAAGCGCATCAA
GGCCTTCGGCCTTCAGGACAAGATCTTTCAGGTCCTGATCCCCACCGAGGAGGTGGTGGAGCTCCGCGAGGGGGGCAAGA
AGGAGGTGGTCCGGAAGAAGCTCTTCCCGGGCTACCTCTTCATCCAGATGGACCTGGGGGACGAGGAGGAGCCCAACGAG
GCCTGGGAGGTGGTGCGCGGCACGCCCGGCATCACGGGCTTCGTCGGGGCGGGGATGCGTCCCGTTCCCCTTTCTCCCGA
CGAGGTGCGGCACATCCTCGAGGTCTCCGGGCTTCTCGGGAAGAAGGAGGCCCCCAAGGCCCAGGTGGCCTTCCGCGAGG
GGGACCAGGTCCGGGTTGTCTCCGGCCCCTTCGCCGACTTCACGGGCACCGTGACCGAGATCAACCCCGAGCGGGGCAAG
GTCAAGGTCATGGTCACCATCTTCGGGCGCGAGACCCCTGTGGAGCTGGACTTCTCCCAGGTGGTCAAGGCCTAG

Upstream 100 bases:

>100_bases
TCGTGGAGGGCACGCAGGCCATCCTCCTCTTCACCTTGGCCTTCATGGTGATCCTCGGGCTTTACGACACGGTCTTCCGC
TTCCTGATAGGGCTTCTGCG

Downstream 100 bases:

>100_bases
AGGCGTTTGCACCCCTAACTTGGGGGGAGCCTAGGAGGGAAAAATGAAGAAAGTTGTTGCGGTGGTCAAACTTCAGCTGC
CCGCGGGCAAGGCCACGCCC

Product: transcription antitermination protein NusG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MSIEWYAVHTLVGQEEKAKANLEKRIKAFGLQDKIFQVLIPTEEVVELREGGKKEVVRKKLFPGYLFIQMDLGDEEEPNE
AWEVVRGTPGITGFVGAGMRPVPLSPDEVRHILEVSGLLGKKEAPKAQVAFREGDQVRVVSGPFADFTGTVTEINPERGK
VKVMVTIFGRETPVELDFSQVVKA

Sequences:

>Translated_184_residues
MSIEWYAVHTLVGQEEKAKANLEKRIKAFGLQDKIFQVLIPTEEVVELREGGKKEVVRKKLFPGYLFIQMDLGDEEEPNE
AWEVVRGTPGITGFVGAGMRPVPLSPDEVRHILEVSGLLGKKEAPKAQVAFREGDQVRVVSGPFADFTGTVTEINPERGK
VKVMVTIFGRETPVELDFSQVVKA
>Mature_183_residues
SIEWYAVHTLVGQEEKAKANLEKRIKAFGLQDKIFQVLIPTEEVVELREGGKKEVVRKKLFPGYLFIQMDLGDEEEPNEA
WEVVRGTPGITGFVGAGMRPVPLSPDEVRHILEVSGLLGKKEAPKAQVAFREGDQVRVVSGPFADFTGTVTEINPERGKV
KVMVTIFGRETPVELDFSQVVKA

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain

Homologues:

Organism=Escherichia coli, GI1790414, Length=181, Percent_Identity=43.646408839779, Blast_Score=146, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUSG_THET8 (P35872)

Other databases:

- EMBL:   L10348
- EMBL:   AP008226
- RefSeq:   YP_143514.1
- PDB:   1NZ8
- PDB:   1NZ9
- PDBsum:   1NZ8
- PDBsum:   1NZ9
- ProteinModelPortal:   P35872
- SMR:   P35872
- STRING:   P35872
- GeneID:   3168047
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA0248
- eggNOG:   COG0250
- HOGENOM:   HBG751162
- OMA:   VASGCEK
- ProtClustDB:   CLSK445381
- BioCyc:   TTHE300852:TTHA0248-MONOMER
- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.30.30.30
- Gene3D:   G3DSA:3.30.70.940
- PRINTS:   PR00338
- SMART:   SM00739
- SMART:   SM00738
- TIGRFAMs:   TIGR00922

Pfam domain/function: PF00467 KOW; PF02357 NusG; SSF82679 Transcrpt_antiterm_NusG_N; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20449; Mature: 20318

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIEWYAVHTLVGQEEKAKANLEKRIKAFGLQDKIFQVLIPTEEVVELREGGKKEVVRKK
CCEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHEEECCHHHHHHHHHCCHHHHHHHH
LFPGYLFIQMDLGDEEEPNEAWEVVRGTPGITGFVGAGMRPVPLSPDEVRHILEVSGLLG
CCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCC
KKEAPKAQVAFREGDQVRVVSGPFADFTGTVTEINPERGKVKVMVTIFGRETPVELDFSQ
CCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEECHHH
VVKA
HHCC
>Mature Secondary Structure 
SIEWYAVHTLVGQEEKAKANLEKRIKAFGLQDKIFQVLIPTEEVVELREGGKKEVVRKK
CEEEEEEEEECCCCHHHHHHHHHHHHHCCCHHHHHEEECCHHHHHHHHHCCHHHHHHHH
LFPGYLFIQMDLGDEEEPNEAWEVVRGTPGITGFVGAGMRPVPLSPDEVRHILEVSGLLG
CCCCEEEEEEECCCCCCCHHHHHHHCCCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHCC
KKEAPKAQVAFREGDQVRVVSGPFADFTGTVTEINPERGKVKVMVTIFGRETPVELDFSQ
CCCCCCEEEEECCCCEEEEEECCCCCCCCEEEEECCCCCEEEEEEEEECCCCCCEECHHH
VVKA
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1447157