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The map label for this gene is yoaE [H]

Identifier: 55980169

GI number: 55980169

Start: 195523

End: 197535

Strand: Direct

Name: yoaE [H]

Synonym: TTHA0200

Alternate gene names: 55980169

Gene position: 195523-197535 (Clockwise)

Preceding gene: 55980168

Following gene: 55980171

Centisome position: 10.57

GC content: 68.6

Gene sequence:

>2013_bases
ATGAGGGCCCGCGCCACCTGTCCCCTGGACTGCCCCGACGCCTGCAGCCTCCTCCTCACCCTGGAGGAAGGGCGCCTCCT
CCGGGTGGAGGGGGACCCCCGCCACCCCATCACCCAAGGCTTCGCCTGCGCCAAGACCTATCGCTACCCGGAGAGGGTAA
GGGAAAGGCTTCTTTACCCCTTGCGCCGGGTGGGGAGAAAGGGCGAGGGGAAGTTCGTGCGGGTCTCCTGGGAAGAGGCC
CTGGACGAGATCGCCAAGCGCCTCATGGAGGTCCTGGACCGGGAGGGGGGCGAGGCCGTCCTCCCCTACCACTACGCCGG
GACCACGGGCCTTGTGGAGAACCAGCACCCCCTGGCCTTCTTCCGGGCCATCGGGGCCTCGGAGCTCTTGGAGACCATCT
GCGCCACGGCGGGGAGCGCCGCCTGGGAGATGACCTACGGCCCCCGCCTCGGCCCCGATCCCGAGGACATCCCCGAAAAC
GCCCGCTATATCCTCCTCTGGGGGATCAATAGCCTCTCCACGAATAGCCACCTCACCCCCTTCCTCAAGGAGGCAAGGAG
GCGGGGGGCCAAGGTGGTCCACATAGACCCCTACGAAAACCTCACCTCCCGCTTCGCCGACCTCCACCTCAAGCTCCGCC
CCGGCACCGACGCCGCCCTGGCCTACGCCTTGGCCCACGTCCTCTTCCGGGAGGGCCTTTTGGACTGGGAGTACCTGGGG
AAGGCGGCGGTGGGCCTGGAGGAGTTCCAGAAGGAAGCGGAAAAGTGGACCCCAAAGCGGGCGAGCGCCCTCACCGGCGT
GCCCGAAGAGGCCATCCTCCGCCTCGCCCGGGAGATGGGGGAGGCGAAGCGGGTCTTCCTGCGGGTGGGCTACGGCATGA
CCCGCCACCCGGGAGGGGGAAACGCCCTCCGCGCCGTGGTCCTCCTCCCCGCCCTCCTCGGGGCCTGGCGCTACCCGGGG
TGCGGGGCCATGCTCTCCACGAGCGGGGCCTTTCCCTTAAACAAGCGCTTCCTCGGGGGGCGGCACCTCCTGGAGGGGGG
ACATCCCCACCAAGGCTACTTCCGGCCGAACCCCAAGGCGCGGGCCGTCAACATGAACCAGCTCGGCACCGCCCTCACGG
AGCTAGACCCTCCCATCCGGGTCCTCTTCGTCTTCAACACGAACCCCCTGGTGGTGGCCCCCAATACGGGGAAGGTGAAG
GCGGGGCTTGCACGGGAGGACCTCTTCACCGTGGTCCTGGAGCAGGTGATGACGGAGACCGCCCGCTTCGCCGACTACCT
CCTCCCCGCCACCCTCTTCTACGAGCACCCCGACCTCTACACGAGCTACGGGCATTACTACCTCTCCTGGAACGAGCCCT
TAAGCCCTCCCGCGGGGGAGGCCCGGCCCAACACCTGGGTCTTCCGGGAGCTGGCGAAGCGGCTCGGCCTGAAGGAGCCC
ACCCTCTACTGGACGGCCGAGGAGGTGGCGGAAAGCCTCCTCGCCTCGGACCACCCTTACCTAGAGGGGATCACCCTGGA
AAGGCTCAAGCGGGAAGGCTTCGTGAAGCTCAACCTTCCCAGGCCCTTCCTCCCCTTCGCCGAAGGGCAGGTGCGCTTCA
GCCCCCCGCCCGAGGTGATCCCCACCGAGCCCCTTCCCGAATACCCCCTGATCCTCCTCACCCCCCCGGCCCACCGCTTC
CTCAACACCACCTACGGGGACGTGAAGGCCCTGGTGGAGGCGGAAGGCGGGGAGCCTAGGCTCCTCATCCACCCCGAGGA
CGCCGAGGCGCGAGGGATTCGGGACGGGATGCTCGTCCACATCCGTTCCCCTTGGGGGAGGATCACGAGGAAGGCCCACG
TCACCGAGGCCCCCATCCCGGGGACGGTGGTCCTCGAGGGCACCTGGTGGGAGAAGTGGGCCCCAGACGGCAAGGGCGTG
AACCACCTCACCTCGGAAAGGCTCACCGACCTGGGCGGGGGAAGCACCTTCCACTCCACCCCCGTGGAGGTGGAGCCCTT
GCGCCTCGCCTAG

Upstream 100 bases:

>100_bases
GAGGGCCTCCTCCTGCGGCTGGACGTCCCCCTGGGGCTTCTGCCGGACCTTTACGAGGAACGGTGCGGCGCCCTCGAGGT
CCTTGGGCTACTCTAAGGGC

Downstream 100 bases:

>100_bases
AGGGCCCTGCGGTAGGCCAGGGCCTCGGCCACGTGGGCCTCCCCCACCCTCTCCTCGCCCAGGAGGTCGGCGACGGTGCG
GGCCACCCGGAGGACGCGGT

Product: molybdopterin oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 670

Protein sequence:

>670_residues
MRARATCPLDCPDACSLLLTLEEGRLLRVEGDPRHPITQGFACAKTYRYPERVRERLLYPLRRVGRKGEGKFVRVSWEEA
LDEIAKRLMEVLDREGGEAVLPYHYAGTTGLVENQHPLAFFRAIGASELLETICATAGSAAWEMTYGPRLGPDPEDIPEN
ARYILLWGINSLSTNSHLTPFLKEARRRGAKVVHIDPYENLTSRFADLHLKLRPGTDAALAYALAHVLFREGLLDWEYLG
KAAVGLEEFQKEAEKWTPKRASALTGVPEEAILRLAREMGEAKRVFLRVGYGMTRHPGGGNALRAVVLLPALLGAWRYPG
CGAMLSTSGAFPLNKRFLGGRHLLEGGHPHQGYFRPNPKARAVNMNQLGTALTELDPPIRVLFVFNTNPLVVAPNTGKVK
AGLAREDLFTVVLEQVMTETARFADYLLPATLFYEHPDLYTSYGHYYLSWNEPLSPPAGEARPNTWVFRELAKRLGLKEP
TLYWTAEEVAESLLASDHPYLEGITLERLKREGFVKLNLPRPFLPFAEGQVRFSPPPEVIPTEPLPEYPLILLTPPAHRF
LNTTYGDVKALVEAEGGEPRLLIHPEDAEARGIRDGMLVHIRSPWGRITRKAHVTEAPIPGTVVLEGTWWEKWAPDGKGV
NHLTSERLTDLGGGSTFHSTPVEVEPLRLA

Sequences:

>Translated_670_residues
MRARATCPLDCPDACSLLLTLEEGRLLRVEGDPRHPITQGFACAKTYRYPERVRERLLYPLRRVGRKGEGKFVRVSWEEA
LDEIAKRLMEVLDREGGEAVLPYHYAGTTGLVENQHPLAFFRAIGASELLETICATAGSAAWEMTYGPRLGPDPEDIPEN
ARYILLWGINSLSTNSHLTPFLKEARRRGAKVVHIDPYENLTSRFADLHLKLRPGTDAALAYALAHVLFREGLLDWEYLG
KAAVGLEEFQKEAEKWTPKRASALTGVPEEAILRLAREMGEAKRVFLRVGYGMTRHPGGGNALRAVVLLPALLGAWRYPG
CGAMLSTSGAFPLNKRFLGGRHLLEGGHPHQGYFRPNPKARAVNMNQLGTALTELDPPIRVLFVFNTNPLVVAPNTGKVK
AGLAREDLFTVVLEQVMTETARFADYLLPATLFYEHPDLYTSYGHYYLSWNEPLSPPAGEARPNTWVFRELAKRLGLKEP
TLYWTAEEVAESLLASDHPYLEGITLERLKREGFVKLNLPRPFLPFAEGQVRFSPPPEVIPTEPLPEYPLILLTPPAHRF
LNTTYGDVKALVEAEGGEPRLLIHPEDAEARGIRDGMLVHIRSPWGRITRKAHVTEAPIPGTVVLEGTWWEKWAPDGKGV
NHLTSERLTDLGGGSTFHSTPVEVEPLRLA
>Mature_670_residues
MRARATCPLDCPDACSLLLTLEEGRLLRVEGDPRHPITQGFACAKTYRYPERVRERLLYPLRRVGRKGEGKFVRVSWEEA
LDEIAKRLMEVLDREGGEAVLPYHYAGTTGLVENQHPLAFFRAIGASELLETICATAGSAAWEMTYGPRLGPDPEDIPEN
ARYILLWGINSLSTNSHLTPFLKEARRRGAKVVHIDPYENLTSRFADLHLKLRPGTDAALAYALAHVLFREGLLDWEYLG
KAAVGLEEFQKEAEKWTPKRASALTGVPEEAILRLAREMGEAKRVFLRVGYGMTRHPGGGNALRAVVLLPALLGAWRYPG
CGAMLSTSGAFPLNKRFLGGRHLLEGGHPHQGYFRPNPKARAVNMNQLGTALTELDPPIRVLFVFNTNPLVVAPNTGKVK
AGLAREDLFTVVLEQVMTETARFADYLLPATLFYEHPDLYTSYGHYYLSWNEPLSPPAGEARPNTWVFRELAKRLGLKEP
TLYWTAEEVAESLLASDHPYLEGITLERLKREGFVKLNLPRPFLPFAEGQVRFSPPPEVIPTEPLPEYPLILLTPPAHRF
LNTTYGDVKALVEAEGGEPRLLIHPEDAEARGIRDGMLVHIRSPWGRITRKAHVTEAPIPGTVVLEGTWWEKWAPDGKGV
NHLTSERLTDLGGGSTFHSTPVEVEPLRLA

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=765, Percent_Identity=28.8888888888889, Blast_Score=211, Evalue=9e-56,
Organism=Escherichia coli, GI171474008, Length=768, Percent_Identity=28.515625, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI87081797, Length=768, Percent_Identity=28.515625, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI3868721, Length=706, Percent_Identity=25.2124645892351, Blast_Score=191, Evalue=2e-49,
Organism=Escherichia coli, GI1787231, Length=743, Percent_Identity=24.2261103633917, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI145693196, Length=666, Percent_Identity=25.5255255255255, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI87081994, Length=676, Percent_Identity=25, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788534, Length=564, Percent_Identity=22.3404255319149, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1787477, Length=176, Percent_Identity=28.9772727272727, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787741, Length=174, Percent_Identity=27.5862068965517, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 74736; Mature: 74736

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRARATCPLDCPDACSLLLTLEEGRLLRVEGDPRHPITQGFACAKTYRYPERVRERLLYP
CCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHCHHHHHHHCCHHHHHHHHHHH
LRRVGRKGEGKFVRVSWEEALDEIAKRLMEVLDREGGEAVLPYHYAGTTGLVENQHPLAF
HHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHH
FRAIGASELLETICATAGSAAWEMTYGPRLGPDPEDIPENARYILLWGINSLSTNSHLTP
HHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCCH
FLKEARRRGAKVVHIDPYENLTSRFADLHLKLRPGTDAALAYALAHVLFREGLLDWEYLG
HHHHHHHCCCEEEEECCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHH
KAAVGLEEFQKEAEKWTPKRASALTGVPEEAILRLAREMGEAKRVFLRVGYGMTRHPGGG
HHHHCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCHHHEEEEEECCCCCCCCCCC
NALRAVVLLPALLGAWRYPGCGAMLSTSGAFPLNKRFLGGRHLLEGGHPHQGYFRPNPKA
HHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCC
RAVNMNQLGTALTELDPPIRVLFVFNTNPLVVAPNTGKVKAGLAREDLFTVVLEQVMTET
EEECHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEECCCHHHHHHHHHHHHHHHHH
ARFADYLLPATLFYEHPDLYTSYGHYYLSWNEPLSPPAGEARPNTWVFRELAKRLGLKEP
HHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
TLYWTAEEVAESLLASDHPYLEGITLERLKREGFVKLNLPRPFLPFAEGQVRFSPPPEVI
EEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCCCC
PTEPLPEYPLILLTPPAHRFLNTTYGDVKALVEAEGGEPRLLIHPEDAEARGIRDGMLVH
CCCCCCCCCEEEECCCHHHHHCCCHHHHHEEEECCCCCCEEEECCCCCCCCCCCCCEEEE
IRSPWGRITRKAHVTEAPIPGTVVLEGTWWEKWAPDGKGVNHLTSERLTDLGGGSTFHST
EECCHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCC
PVEVEPLRLA
CCCCCCCCCC
>Mature Secondary Structure
MRARATCPLDCPDACSLLLTLEEGRLLRVEGDPRHPITQGFACAKTYRYPERVRERLLYP
CCCCCCCCCCCCCCCEEEEEECCCCEEEECCCCCCCHHHCHHHHHHHCCHHHHHHHHHHH
LRRVGRKGEGKFVRVSWEEALDEIAKRLMEVLDREGGEAVLPYHYAGTTGLVENQHPLAF
HHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCHHH
FRAIGASELLETICATAGSAAWEMTYGPRLGPDPEDIPENARYILLWGINSLSTNSHLTP
HHHCCHHHHHHHHHHCCCCCEEEEECCCCCCCCHHCCCCCCCEEEEECCCCCCCCCCCCH
FLKEARRRGAKVVHIDPYENLTSRFADLHLKLRPGTDAALAYALAHVLFREGLLDWEYLG
HHHHHHHCCCEEEEECCHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHCCCCHHHHH
KAAVGLEEFQKEAEKWTPKRASALTGVPEEAILRLAREMGEAKRVFLRVGYGMTRHPGGG
HHHHCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHCHHHEEEEEECCCCCCCCCCC
NALRAVVLLPALLGAWRYPGCGAMLSTSGAFPLNKRFLGGRHLLEGGHPHQGYFRPNPKA
HHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCC
RAVNMNQLGTALTELDPPIRVLFVFNTNPLVVAPNTGKVKAGLAREDLFTVVLEQVMTET
EEECHHHHHHHHHHCCCCEEEEEEECCCCEEECCCCCCEECCCHHHHHHHHHHHHHHHHH
ARFADYLLPATLFYEHPDLYTSYGHYYLSWNEPLSPPAGEARPNTWVFRELAKRLGLKEP
HHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
TLYWTAEEVAESLLASDHPYLEGITLERLKREGFVKLNLPRPFLPFAEGQVRFSPPPEVI
EEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHCCEEEECCCCCCCCCCCCEEEECCCCCCC
PTEPLPEYPLILLTPPAHRFLNTTYGDVKALVEAEGGEPRLLIHPEDAEARGIRDGMLVH
CCCCCCCCCEEEECCCHHHHHCCCHHHHHEEEECCCCCCEEEECCCCCCCCCCCCCEEEE
IRSPWGRITRKAHVTEAPIPGTVVLEGTWWEKWAPDGKGVNHLTSERLTDLGGGSTFHST
EECCHHHHHHHCCCCCCCCCCEEEEECCCHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCC
PVEVEPLRLA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]