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The map label for this gene is murA [H]

Identifier: 55980109

GI number: 55980109

Start: 136879

End: 138156

Strand: Direct

Name: murA [H]

Synonym: TTHA0140

Alternate gene names: 55980109

Gene position: 136879-138156 (Clockwise)

Preceding gene: 55980104

Following gene: 55980111

Centisome position: 7.4

GC content: 72.3

Gene sequence:

>1278_bases
GTGGGCGTGAGCCGGGTGCTGCACGTGGAAGGCGGCACCCCCTTGAAGGGGGAGCTTAGGGTCTACCCGGCCAAGAACGC
CGCCCTGCCCATCCTCGCCGCGAGCCTCCTCACCCCCGAGCCCATCACCCTGGTGGAGGTGCCGAGGCTTAGGGACGTGG
AGGTGATGCTGGAGCTCCTCGCCCACCTGGGCACCCAGTACGCCTGGGAGGGCCGGACCCTCCACCTCCAGACCCCGGAG
ATCAAAAGCACCCACGCCCCCTACGAGCTCGTGGGCCAGATGCGGGCGAGCTTCATCGTCTGGGGAGCCCTCCTCGCTCG
GGCCGGGGAGGGGCACGTCTCCATGCCGGGGGGATGCGCCTTCGGCTTCCGCCCCGTGGACCAACACATCAAGGCCCTCG
AGGCCCTGGGGGCGGAGGTCTGGGAGGAGGACGGCACCTTCCACGCCCGCAGGACCCGCCCCCTCTCGGGGCGGGTGGTC
TTTGACCTGCCCACCGTGGGGGGCACGGAGCAGGCCATGCTGGCCGTGGCCCTGGGCGGGGAGGCCACCCTGGTCCAGGC
GGCGGTGGAGCCCGAGGTGGTGGACCTGGGCCACTTCCTCGCCCTCCTCGGGGCCGAGGTGGAGGGGCTGGGAAGCCCCA
TCGTCCGCATCAAGGGGGCGCCCCGGCTAAAGGGCGGCACCTACCGCATCATCCCCGACCGCATAGAGGCCGGGACCTAC
CTCCTGGCGGCGGCCGCCACCCGGGGAAGCCTCACCCTGGAAGGCGTGCGCCCCGACCACCTGGACGCCCTTTTGGACAA
GCTTTGGCGCTCGGGGCACCGGCTCGAGGTGGGGGAAGACTGGATCCGCTTCCGGGCCACCCCGGACCCCGCCCCCTTCC
ACGTGGAGGCCCGGGAGTACCCGGGCTTTCCCACGGACCTCCAGCCCATCGCCACCGCCTACCTGGCCACCGTCCCCGGC
CAGAGCACGGTGGTGGACCGCATCTACCCCGACCGCTTCACCCACGTGGGGGAGCTGGCCCGCATGGGGGCGGAGCTCTA
CCTGCGGGACCGGATCCTCACCGTCCAGGGCAGGCGGCTCCACGGCGCCCAGGTCAAGGCCCTGGACATCCGGGCGGGAG
GGGCCTTGGTGGTGGCGGCCCTGAGCGCCGAAGGCGCCTCGGAGATTGAGGGCGTCTACTTCCTGGAGCGGGGCTACGAG
CACCTCACGGAAAGGCTCCAGGCCCTGGGGGCCCGGGTGCACCTCCGGGAAAGCCCCGTGGCCCTGGCTGCCGACTGA

Upstream 100 bases:

>100_bases
CCTAGTGTAGCAAAAGCCCCCTTTGCTTGACAATGCCGCACCTCCACCCTATGCTCAACTTGAGTATGATGCGCAAGGGG
CGCGTGAGGGGGCGGAAAGC

Downstream 100 bases:

>100_bases
GGCCCCGGCGGGGCGGGGCGCTCACCCCAGGAGGCGGAGGGCCTCCGGGAAGCGGAAGAAGAGGCGGTCCCGGGCGAGCT
CAGGGCTGTAGGCCCGCTCC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGVSRVLHVEGGTPLKGELRVYPAKNAALPILAASLLTPEPITLVEVPRLRDVEVMLELLAHLGTQYAWEGRTLHLQTPE
IKSTHAPYELVGQMRASFIVWGALLARAGEGHVSMPGGCAFGFRPVDQHIKALEALGAEVWEEDGTFHARRTRPLSGRVV
FDLPTVGGTEQAMLAVALGGEATLVQAAVEPEVVDLGHFLALLGAEVEGLGSPIVRIKGAPRLKGGTYRIIPDRIEAGTY
LLAAAATRGSLTLEGVRPDHLDALLDKLWRSGHRLEVGEDWIRFRATPDPAPFHVEAREYPGFPTDLQPIATAYLATVPG
QSTVVDRIYPDRFTHVGELARMGAELYLRDRILTVQGRRLHGAQVKALDIRAGGALVVAALSAEGASEIEGVYFLERGYE
HLTERLQALGARVHLRESPVALAAD

Sequences:

>Translated_425_residues
MGVSRVLHVEGGTPLKGELRVYPAKNAALPILAASLLTPEPITLVEVPRLRDVEVMLELLAHLGTQYAWEGRTLHLQTPE
IKSTHAPYELVGQMRASFIVWGALLARAGEGHVSMPGGCAFGFRPVDQHIKALEALGAEVWEEDGTFHARRTRPLSGRVV
FDLPTVGGTEQAMLAVALGGEATLVQAAVEPEVVDLGHFLALLGAEVEGLGSPIVRIKGAPRLKGGTYRIIPDRIEAGTY
LLAAAATRGSLTLEGVRPDHLDALLDKLWRSGHRLEVGEDWIRFRATPDPAPFHVEAREYPGFPTDLQPIATAYLATVPG
QSTVVDRIYPDRFTHVGELARMGAELYLRDRILTVQGRRLHGAQVKALDIRAGGALVVAALSAEGASEIEGVYFLERGYE
HLTERLQALGARVHLRESPVALAAD
>Mature_424_residues
GVSRVLHVEGGTPLKGELRVYPAKNAALPILAASLLTPEPITLVEVPRLRDVEVMLELLAHLGTQYAWEGRTLHLQTPEI
KSTHAPYELVGQMRASFIVWGALLARAGEGHVSMPGGCAFGFRPVDQHIKALEALGAEVWEEDGTFHARRTRPLSGRVVF
DLPTVGGTEQAMLAVALGGEATLVQAAVEPEVVDLGHFLALLGAEVEGLGSPIVRIKGAPRLKGGTYRIIPDRIEAGTYL
LAAAATRGSLTLEGVRPDHLDALLDKLWRSGHRLEVGEDWIRFRATPDPAPFHVEAREYPGFPTDLQPIATAYLATVPGQ
STVVDRIYPDRFTHVGELARMGAELYLRDRILTVQGRRLHGAQVKALDIRAGGALVVAALSAEGASEIEGVYFLERGYEH
LTERLQALGARVHLRESPVALAAD

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=412, Percent_Identity=42.4757281553398, Blast_Score=321, Evalue=6e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45978; Mature: 45847

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVSRVLHVEGGTPLKGELRVYPAKNAALPILAASLLTPEPITLVEVPRLRDVEVMLELL
CCCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AHLGTQYAWEGRTLHLQTPEIKSTHAPYELVGQMRASFIVWGALLARAGEGHVSMPGGCA
HHCCCCEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
FGFRPVDQHIKALEALGAEVWEEDGTFHARRTRPLSGRVVFDLPTVGGTEQAMLAVALGG
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEEEEECC
EATLVQAAVEPEVVDLGHFLALLGAEVEGLGSPIVRIKGAPRLKGGTYRIIPDRIEAGTY
CCEEEEECCCCCHHHHHHHHHHHCCCHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCEE
LLAAAATRGSLTLEGVRPDHLDALLDKLWRSGHRLEVGEDWIRFRATPDPAPFHVEAREY
EEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEHHCC
PGFPTDLQPIATAYLATVPGQSTVVDRIYPDRFTHVGELARMGAELYLRDRILTVQGRRL
CCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHCCHHEEEEEEEEEEECCEE
HGAQVKALDIRAGGALVVAALSAEGASEIEGVYFLERGYEHLTERLQALGARVHLRESPV
CCCEEEEEEEECCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCE
ALAAD
EEECC
>Mature Secondary Structure 
GVSRVLHVEGGTPLKGELRVYPAKNAALPILAASLLTPEPITLVEVPRLRDVEVMLELL
CCCEEEEECCCCCCCCCEEEEECCCCCHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHH
AHLGTQYAWEGRTLHLQTPEIKSTHAPYELVGQMRASFIVWGALLARAGEGHVSMPGGCA
HHCCCCEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCC
FGFRPVDQHIKALEALGAEVWEEDGTFHARRTRPLSGRVVFDLPTVGGTEQAMLAVALGG
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEEEEECC
EATLVQAAVEPEVVDLGHFLALLGAEVEGLGSPIVRIKGAPRLKGGTYRIIPDRIEAGTY
CCEEEEECCCCCHHHHHHHHHHHCCCHHCCCCCEEEECCCCCCCCCEEEEECCCCCCCEE
LLAAAATRGSLTLEGVRPDHLDALLDKLWRSGHRLEVGEDWIRFRATPDPAPFHVEAREY
EEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEHHCC
PGFPTDLQPIATAYLATVPGQSTVVDRIYPDRFTHVGELARMGAELYLRDRILTVQGRRL
CCCCCCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHCCHHEEEEEEEEEEECCEE
HGAQVKALDIRAGGALVVAALSAEGASEIEGVYFLERGYEHLTERLQALGARVHLRESPV
CCCEEEEEEEECCCEEEEEEECCCCCHHCCHHHHHHHHHHHHHHHHHHCCCEEEEECCCE
ALAAD
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA