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The map label for this gene is oxyR [H]

Identifier: 55980092

GI number: 55980092

Start: 123473

End: 124426

Strand: Direct

Name: oxyR [H]

Synonym: TTHA0123

Alternate gene names: 55980092

Gene position: 123473-124426 (Clockwise)

Preceding gene: 55980090

Following gene: 55980093

Centisome position: 6.68

GC content: 69.18

Gene sequence:

>954_bases
ATGAAGCTGACCCTAGACCAGCTGCGCTACCTCGTGGCCTTGGCCGAGGAAGGAAGCTTCACCCGGGCCGCGGAACGGGT
CTACCTCACCCAGCCCGCCCTCTCCGTCCAGATCCGCAAGCTGGAGGAAGCCCTGGGGACAAGGCTCTTTGACCGGAGGA
AGGGCACGCTCACGGAGGCGGGCCGGGTGGCGGTGGCCCAGGCCCGGAGGGTCCTCGAGGAAGTGGAAAGGCTCAGGCTT
TTGGTGCAGGGGGAAGAGGCCTGCTTCCAAGGCCCCTTCCGGCTCGGGGTCATCCCCACCCTTGCCCCCTACCTCCTTCC
CCGGCTCCTTCCGGAGCTGAAGGCGCGTTACCCCCGGCTTTCCCTCTCGGTGCGGGAGGAGCTCACCCCGGGGATCGTAC
GGGGGTTAGAGGAAGGAAGCCTGGACGCAGGGCTTGTGGGCACGGAGGAGCGGCACCCAGGCCTCGGGGCCGAGCCCCTC
TTCGCCGAGGCCTTCTGGGCCTATGTGGCCCCGGGCCACCCCCTCTTTGAGCGGGAGGCGGTCCATCCTCTGGAGATTCC
CCTCGAGGACACCTGGGTCCTCGCCGAGGGACACTGCTTCCGGGACCAGGTCCTCTCCGTGTGCCGTCCGAGCCTCGGCG
GGCGGTCCGTGGAGTTCCAAAGCGGAGACCTGGAGACCCTCGTCCGCTTGGTGGACGCCGTGGGGGGGCTCACCCTCCTC
CCCGAGGTGGCCCTCTGGACCCTCTCTCCGGCCCAAAGGACCCGGTTGCGCCCCCTAAGCCCCCCCGGGGCCGGGCGCAC
CGTCTACCTCCTTTTCCGGGAGGGAAGCCTCAAGGCTCCCTTGCTCCGGGCCCTGGCCGAGGAAGCGCGGCGAGCCTTCG
CCCTGTTGCGCTCCAACGCAAGGGCGCAAGAAAGCGCTATGATGGGGGCGGAGGTTCGCCATGACCAAGGCTGA

Upstream 100 bases:

>100_bases
CCTTTCGCCCTGGGCTTGGCCCCAGGGACGCCCTCACCCTAAAAGGGGGAGTGCCCATAAGTCAAATAGATCTTGCTTGG
CGCTAGAATAAGCCAGGATT

Downstream 100 bases:

>100_bases
GGCCAAGGGCGGCGACGTGCAGATCAAGGCCGGGCTCATCTGGATGAACGGGGCCTTTGTCCCCCAGGAGGAGGCCAAGA
CCAGCGTCCTAAGCCACGCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKLTLDQLRYLVALAEEGSFTRAAERVYLTQPALSVQIRKLEEALGTRLFDRRKGTLTEAGRVAVAQARRVLEEVERLRL
LVQGEEACFQGPFRLGVIPTLAPYLLPRLLPELKARYPRLSLSVREELTPGIVRGLEEGSLDAGLVGTEERHPGLGAEPL
FAEAFWAYVAPGHPLFEREAVHPLEIPLEDTWVLAEGHCFRDQVLSVCRPSLGGRSVEFQSGDLETLVRLVDAVGGLTLL
PEVALWTLSPAQRTRLRPLSPPGAGRTVYLLFREGSLKAPLLRALAEEARRAFALLRSNARAQESAMMGAEVRHDQG

Sequences:

>Translated_317_residues
MKLTLDQLRYLVALAEEGSFTRAAERVYLTQPALSVQIRKLEEALGTRLFDRRKGTLTEAGRVAVAQARRVLEEVERLRL
LVQGEEACFQGPFRLGVIPTLAPYLLPRLLPELKARYPRLSLSVREELTPGIVRGLEEGSLDAGLVGTEERHPGLGAEPL
FAEAFWAYVAPGHPLFEREAVHPLEIPLEDTWVLAEGHCFRDQVLSVCRPSLGGRSVEFQSGDLETLVRLVDAVGGLTLL
PEVALWTLSPAQRTRLRPLSPPGAGRTVYLLFREGSLKAPLLRALAEEARRAFALLRSNARAQESAMMGAEVRHDQG
>Mature_317_residues
MKLTLDQLRYLVALAEEGSFTRAAERVYLTQPALSVQIRKLEEALGTRLFDRRKGTLTEAGRVAVAQARRVLEEVERLRL
LVQGEEACFQGPFRLGVIPTLAPYLLPRLLPELKARYPRLSLSVREELTPGIVRGLEEGSLDAGLVGTEERHPGLGAEPL
FAEAFWAYVAPGHPLFEREAVHPLEIPLEDTWVLAEGHCFRDQVLSVCRPSLGGRSVEFQSGDLETLVRLVDAVGGLTLL
PEVALWTLSPAQRTRLRPLSPPGAGRTVYLLFREGSLKAPLLRALAEEARRAFALLRSNARAQESAMMGAEVRHDQG

Specific function: Required for the induction of a regulon of hydrogen peroxide inducible genes such as catalase and glutathione- reductase [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=280, Percent_Identity=36.7857142857143, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI157672245, Length=297, Percent_Identity=32.6599326599327, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693105, Length=312, Percent_Identity=28.525641025641, Blast_Score=95, Evalue=7e-21,
Organism=Escherichia coli, GI1787879, Length=294, Percent_Identity=29.9319727891156, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081904, Length=182, Percent_Identity=33.5164835164835, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788887, Length=179, Percent_Identity=34.0782122905028, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787601, Length=304, Percent_Identity=25.3289473684211, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787806, Length=281, Percent_Identity=24.5551601423488, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787530, Length=185, Percent_Identity=29.7297297297297, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788748, Length=175, Percent_Identity=28, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789204, Length=216, Percent_Identity=28.2407407407407, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786713, Length=181, Percent_Identity=34.2541436464088, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=269, Percent_Identity=24.907063197026, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=250, Percent_Identity=30, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788626, Length=284, Percent_Identity=29.9295774647887, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=177, Percent_Identity=25.4237288135593, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789173, Length=172, Percent_Identity=29.6511627906977, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790262, Length=299, Percent_Identity=26.7558528428094, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1790208, Length=259, Percent_Identity=27.4131274131274, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35065; Mature: 35065

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTLDQLRYLVALAEEGSFTRAAERVYLTQPALSVQIRKLEEALGTRLFDRRKGTLTEA
CCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GRVAVAQARRVLEEVERLRLLVQGEEACFQGPFRLGVIPTLAPYLLPRLLPELKARYPRL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
SLSVREELTPGIVRGLEEGSLDAGLVGTEERHPGLGAEPLFAEAFWAYVAPGHPLFEREA
CCHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCC
VHPLEIPLEDTWVLAEGHCFRDQVLSVCRPSLGGRSVEFQSGDLETLVRLVDAVGGLTLL
CCCEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHH
PEVALWTLSPAQRTRLRPLSPPGAGRTVYLLFREGSLKAPLLRALAEEARRAFALLRSNA
HHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
RAQESAMMGAEVRHDQG
HHHHHHHHCCHHCCCCC
>Mature Secondary Structure
MKLTLDQLRYLVALAEEGSFTRAAERVYLTQPALSVQIRKLEEALGTRLFDRRKGTLTEA
CCCCHHHHHHHHHHHCCCCHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHHCCCCHHHH
GRVAVAQARRVLEEVERLRLLVQGEEACFQGPFRLGVIPTLAPYLLPRLLPELKARYPRL
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
SLSVREELTPGIVRGLEEGSLDAGLVGTEERHPGLGAEPLFAEAFWAYVAPGHPLFEREA
CCHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHCC
VHPLEIPLEDTWVLAEGHCFRDQVLSVCRPSLGGRSVEFQSGDLETLVRLVDAVGGLTLL
CCCEECCCCCCEEEECCCCHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHCCHHHH
PEVALWTLSPAQRTRLRPLSPPGAGRTVYLLFREGSLKAPLLRALAEEARRAFALLRSNA
HHHHHHCCCHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCC
RAQESAMMGAEVRHDQG
HHHHHHHHCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA