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The map label for this gene is nqo7

Identifier: 55980053

GI number: 55980053

Start: 83765

End: 84124

Strand: Direct

Name: nqo7

Synonym: TTHA0084

Alternate gene names: 55980053

Gene position: 83765-84124 (Clockwise)

Preceding gene: 55980052

Following gene: 55980054

Centisome position: 4.53

GC content: 65.56

Gene sequence:

>360_bases
TTGGCGCCGATCCAAGAGTACGTGGGCACGCTGATCTACGTGGGGGTGGCCCTCTTTATTGGGGTGGCGGCCCTTTTGGT
GGGGGCCCTCCTCGGCCCCAAGAAGCCGGGGCGGGCCAAGCTCATGCCCTACGAGTCGGGGAACGACCCCGCCGGGGAGG
TGAAGCGCTTTCCCGTCCACTTCTACGTGGTGGCCATGCTCTTCATCCTCTTTGACGTGGAGGTGGCCTTCCTCTGGCCC
TACGCCGTGAGCGCGGGCGGGCTTGGCCTCTATGGCTTCCTCGGGGTCCTCGCCTTCACCCTCCTCCTCTTCGTGGGCTT
CCTCTACGAGTGGTGGAAGGGGGTGATGCGGTGGCACTGA

Upstream 100 bases:

>100_bases
GCGCCCCACCCCGGGGTGATAAGATGGGCGGGAAATGAGGCCGGCCCCTTTGGGGCTTTGGGGACCGGCTTCGTGAAGAA
AGGCACGAAAGGAGGGGACC

Downstream 100 bases:

>100_bases
AGGACCTTTTTGAGCGGGACGTCCAGGAGCTGGAACGGGAGGGGATCCTCTTCACCACCTTGGAGAAGCTCGTGGCCTGG
GGGCGGAGCAACTCCCTGTG

Product: NADH-quinone oxidoreductase subunit 7

Products: NA

Alternate protein names: NADH dehydrogenase I chain 7; NDH-1 subunit 7

Number of amino acids: Translated: 119; Mature: 118

Protein sequence:

>119_residues
MAPIQEYVGTLIYVGVALFIGVAALLVGALLGPKKPGRAKLMPYESGNDPAGEVKRFPVHFYVVAMLFILFDVEVAFLWP
YAVSAGGLGLYGFLGVLAFTLLLFVGFLYEWWKGVMRWH

Sequences:

>Translated_119_residues
MAPIQEYVGTLIYVGVALFIGVAALLVGALLGPKKPGRAKLMPYESGNDPAGEVKRFPVHFYVVAMLFILFDVEVAFLWP
YAVSAGGLGLYGFLGVLAFTLLLFVGFLYEWWKGVMRWH
>Mature_118_residues
APIQEYVGTLIYVGVALFIGVAALLVGALLGPKKPGRAKLMPYESGNDPAGEVKRFPVHFYVVAMLFILFDVEVAFLWPY
AVSAGGLGLYGFLGVLAFTLLLFVGFLYEWWKGVMRWH

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every

COG id: COG0838

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 3 (chain A)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 3 family

Homologues:

Organism=Escherichia coli, GI1788625, Length=108, Percent_Identity=34.2592592592593, Blast_Score=61, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQO7_THET8 (Q56217)

Other databases:

- EMBL:   U52917
- EMBL:   AP008226
- PIR:   T11898
- RefSeq:   YP_143350.1
- ProteinModelPortal:   Q56217
- STRING:   Q56217
- GeneID:   3168352
- GenomeReviews:   AP008226_GR
- KEGG:   ttj:TTHA0084
- eggNOG:   COG0838
- HOGENOM:   HBG605540
- OMA:   GRFPIKY
- ProtClustDB:   CLSK738967
- BioCyc:   TTHE300852:TTHA0084-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_01394
- InterPro:   IPR023043
- InterPro:   IPR000440
- PANTHER:   PTHR11058

Pfam domain/function: PF00507 Oxidored_q4

EC number: =1.6.99.5

Molecular weight: Translated: 13145; Mature: 13014

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x10bc77b4)-; HASH(0x1234b9ec)-; HASH(0x12322f18)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPIQEYVGTLIYVGVALFIGVAALLVGALLGPKKPGRAKLMPYESGNDPAGEVKRFPVH
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHH
FYVVAMLFILFDVEVAFLWPYAVSAGGLGLYGFLGVLAFTLLLFVGFLYEWWKGVMRWH
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
>Mature Secondary Structure 
APIQEYVGTLIYVGVALFIGVAALLVGALLGPKKPGRAKLMPYESGNDPAGEVKRFPVH
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCHHHHHHHHHH
FYVVAMLFILFDVEVAFLWPYAVSAGGLGLYGFLGVLAFTLLLFVGFLYEWWKGVMRWH
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020134