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The map label for this gene is alr [H]

Identifier: 55980031

GI number: 55980031

Start: 58555

End: 59637

Strand: Reverse

Name: alr [H]

Synonym: TTHA0062

Alternate gene names: 55980031

Gene position: 59637-58555 (Counterclockwise)

Preceding gene: 55980032

Following gene: 55980030

Centisome position: 3.22

GC content: 73.78

Gene sequence:

>1083_bases
GTGCGCCCGGGCGGGTATCCTAAAGGGGTGCAGGCCCGGGCCTGGGTGGAGGTGGACCTCGCCGCCCTCTGGGCGAACTA
CCGGCTTCTCGCCGGGCGGGCGGGAGGGGAGGTGATCCCCGTGCTCAAGGCGGACGCCTACGGCCACGGGGCCCTTCCCC
TCGCCCGCTTCCTGGAGGGAAAGGGCGTGGGGCGCTTCGCCGTGGCCACCCTGGAGGAGGGGAGGCGCCTCCGGGAAGGG
GGCATCAAGGGGGAGGTCCTCCTTCTCGGAAGCCTCCACCCCCTGGAGGCGGAGGAGGCCTTGAGGCTTGGCCTCGTGCC
CACCCTCTCCAACCTGGAGGCGGCGGAGGCCCTTTCCCAGAGGGCCCGCGCCCTGGGCCTTGTGCCCCGGGCCCACCTCA
AGGTGGATACGGGCATGAACCGGGTGGGCTTTCCCTCGGAGGAGGCGGTCTCGGCCCTGCGGGCGGTGGAGGCCCTGGGG
GTGAGGGTGGAGGGCGTCTACACCCACCTCGCCACCGCCGGGGAGGACGCGGCCTTCGTGGAGACGCAGCGGCGCCGCTT
CCAGGAGGTGCGCCGCGCCTTGGGGGAGGGGTACTTCTACCACCTGGAGAACTCCCTGGGCCTCCTCCGCCACGGGGCCA
CGGCGGGGGTGCGGGTGGGGCTCGCCCTCTACGGCCTCGTCCCCGGCTTTGGCCTCAGGCCCATCCTCCGGATCCTCGCC
CGGCCCACCCTGGTGAAGCGCCTGAAGGCGGGGGACCGGGTGGGGTACGGGGGGGTCTATGTGGCCCGGGGCGGGGAGTG
GCTCGCCACCCTGCCCGTGGGGTACGCCGACGGGCTTCCCTGGGGGGCGGTGCGGTTCGTGAAGGGGCCGGACGGGCGCC
TTCTGGAGGTGGCGGGCCGGATCTCCATGGACCAGACCACCGTCCTCCTCCCCGGCCCCGTGGGCCTCGAGGCCGTGTTT
GAGGTGCTCTCGGCCGACTTCGGCCCCACGGGCCTCCTCGCCTGGGCCGAGGCCCGGGGCACCCTCCCTTATGAGGTGGC
CGTCCACCTTTCCCGGAGGCTTCCCCGCCGCTACCTGGAGTAG

Upstream 100 bases:

>100_bases
TCGCCCGCCTCCTCGGCCTCCTGGACCGGCGGCAGTTCAGGCTGGACCCCGACCCCTTCCACTTCGTGGGGCTTTTGGAG
GACTGAGCGCCCCCAAGGGC

Downstream 100 bases:

>100_bases
GCTTAGGGCGTGCAGGCCGTCCGCCTCTTCCAGGGTTACCTCTGGCACCCCCGGGCCCTCGCCCTGGACCTAAAGGCCCT
CCTCCCCGGCGAGGTGGCCG

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRPGGYPKGVQARAWVEVDLAALWANYRLLAGRAGGEVIPVLKADAYGHGALPLARFLEGKGVGRFAVATLEEGRRLREG
GIKGEVLLLGSLHPLEAEEALRLGLVPTLSNLEAAEALSQRARALGLVPRAHLKVDTGMNRVGFPSEEAVSALRAVEALG
VRVEGVYTHLATAGEDAAFVETQRRRFQEVRRALGEGYFYHLENSLGLLRHGATAGVRVGLALYGLVPGFGLRPILRILA
RPTLVKRLKAGDRVGYGGVYVARGGEWLATLPVGYADGLPWGAVRFVKGPDGRLLEVAGRISMDQTTVLLPGPVGLEAVF
EVLSADFGPTGLLAWAEARGTLPYEVAVHLSRRLPRRYLE

Sequences:

>Translated_360_residues
MRPGGYPKGVQARAWVEVDLAALWANYRLLAGRAGGEVIPVLKADAYGHGALPLARFLEGKGVGRFAVATLEEGRRLREG
GIKGEVLLLGSLHPLEAEEALRLGLVPTLSNLEAAEALSQRARALGLVPRAHLKVDTGMNRVGFPSEEAVSALRAVEALG
VRVEGVYTHLATAGEDAAFVETQRRRFQEVRRALGEGYFYHLENSLGLLRHGATAGVRVGLALYGLVPGFGLRPILRILA
RPTLVKRLKAGDRVGYGGVYVARGGEWLATLPVGYADGLPWGAVRFVKGPDGRLLEVAGRISMDQTTVLLPGPVGLEAVF
EVLSADFGPTGLLAWAEARGTLPYEVAVHLSRRLPRRYLE
>Mature_360_residues
MRPGGYPKGVQARAWVEVDLAALWANYRLLAGRAGGEVIPVLKADAYGHGALPLARFLEGKGVGRFAVATLEEGRRLREG
GIKGEVLLLGSLHPLEAEEALRLGLVPTLSNLEAAEALSQRARALGLVPRAHLKVDTGMNRVGFPSEEAVSALRAVEALG
VRVEGVYTHLATAGEDAAFVETQRRRFQEVRRALGEGYFYHLENSLGLLRHGATAGVRVGLALYGLVPGFGLRPILRILA
RPTLVKRLKAGDRVGYGGVYVARGGEWLATLPVGYADGLPWGAVRFVKGPDGRLLEVAGRISMDQTTVLLPGPVGLEAVF
EVLSADFGPTGLLAWAEARGTLPYEVAVHLSRRLPRRYLE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=364, Percent_Identity=32.4175824175824, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790487, Length=348, Percent_Identity=29.5977011494253, Blast_Score=92, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38652; Mature: 38652

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPGGYPKGVQARAWVEVDLAALWANYRLLAGRAGGEVIPVLKADAYGHGALPLARFLEG
CCCCCCCCCCCEEEEEEHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHCC
KGVGRFAVATLEEGRRLREGGIKGEVLLLGSLHPLEAEEALRLGLVPTLSNLEAAEALSQ
CCCCCEEEHHHHHCHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
RARALGLVPRAHLKVDTGMNRVGFPSEEAVSALRAVEALGVRVEGVYTHLATAGEDAAFV
HHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCHHHH
ETQRRRFQEVRRALGEGYFYHLENSLGLLRHGATAGVRVGLALYGLVPGFGLRPILRILA
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
RPTLVKRLKAGDRVGYGGVYVARGGEWLATLPVGYADGLPWGAVRFVKGPDGRLLEVAGR
CHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEEECC
ISMDQTTVLLPGPVGLEAVFEVLSADFGPTGLLAWAEARGTLPYEVAVHLSRRLPRRYLE
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPGGYPKGVQARAWVEVDLAALWANYRLLAGRAGGEVIPVLKADAYGHGALPLARFLEG
CCCCCCCCCCCEEEEEEHHHHHHHHCCEEEEECCCCCEEEEEEECCCCCCCHHHHHHHCC
KGVGRFAVATLEEGRRLREGGIKGEVLLLGSLHPLEAEEALRLGLVPTLSNLEAAEALSQ
CCCCCEEEHHHHHCHHHHHCCCCCEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
RARALGLVPRAHLKVDTGMNRVGFPSEEAVSALRAVEALGVRVEGVYTHLATAGEDAAFV
HHHHHCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCEEEHHHHHHHHCCCCHHHH
ETQRRRFQEVRRALGEGYFYHLENSLGLLRHGATAGVRVGLALYGLVPGFGLRPILRILA
HHHHHHHHHHHHHHCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHH
RPTLVKRLKAGDRVGYGGVYVARGGEWLATLPVGYADGLPWGAVRFVKGPDGRLLEVAGR
CHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEEECC
ISMDQTTVLLPGPVGLEAVFEVLSADFGPTGLLAWAEARGTLPYEVAVHLSRRLPRRYLE
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA