| Definition | Thermus thermophilus HB8 chromosome, complete genome. |
|---|---|
| Accession | NC_006461 |
| Length | 1,849,742 |
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The map label for this gene is acyII [H]
Identifier: 55979993
GI number: 55979993
Start: 25272
End: 27593
Strand: Reverse
Name: acyII [H]
Synonym: TTHA0024
Alternate gene names: 55979993
Gene position: 27593-25272 (Counterclockwise)
Preceding gene: 55980010
Following gene: 55979991
Centisome position: 1.49
GC content: 68.09
Gene sequence:
>2322_bases ATGCTTTTTCCAACCATGAAGCGCTTCTTGCGGGGGCTGGCCCGGCTTTTGGGCCTTTTCCTCTTCCTTGCCCTTCTCCT CGGCTTCTCGGGGTACCTCTACCTCAGGGCCTCCCTGCCCCAAGGGGAAGGCCGCATCGCCCTGGAGGGGCTTTCCGCCC CGGTGGAGGTGGTCCGGGACGGCAAGGGGGTGGTGCGCATCCGGGCGGCGACGCTTAAGGACCTCTTCTTCGCCCAGGGT TTCGTCCACGCCCAGGAGCGGCTTTGGCAGATGGAGTTCCAGCGCCGGGTGGGCCAGGGGCGCTTGAGCGAGATCCTGGG GGAGGCCACGCTTCCCCAGGACCGGTTCCTCCGCACCTGGGGCTTTTACCGGGCGGCCCGGGCGGCCTACGGGAGGCTCT ACCCCGAGGAGAAGGAGGCGGTGGACGCCTACGCCGCCGGGGTGAACGCCTTCTTGGCCTCTGGGGCCCCTCTGCCCCCC GAGTTTAGGCTCCTCGGCTTCCGCCCCGAGCCCTGGACGGGCCCCGACGTCCTGGTCTGGGCCAAGATGATGAGCTACGA CCTCTCGGGGAACTGGGAGGAGGAGCTAAAACGCCACCGCCTCCTCGCCCGGGGGGTAAGCCCAAAGCGGCTCCTTGAGC TCATGCCCCCTTACCCCGAGGACGCCCCCACCATCCTTTCCGCTGAGGACCTTAAGCTTCCCCTCAAGCGGGAAGAGGCC CCAAGCGCCCTCCTCCGGATGGCCCCGCCCCGCTTCATGGAGGCCAGCAACAACTGGGTGGTCTCGGGAAGCCGCACCAC CACGGGCAAGCCCTTCCTCGCCAACGACCCCCACCTCGCCCTCCAGGCCCCGAGCCTCTGGTTCCTCATGGCCCTCGAGG CCCCAGGGCTTAGGGCCATCGGGGCCACCTTGCCCGGCCTGCCCGGTGTCGTCATCGGGCGGAACGAGCGCATCGCCTGG GGGGTGACGAACGTGGGGGCGGACGTGGAGGACCTCTACCTCCTGGAGGAGGTGGAAGGAAGAGGCTACCGCTACAAGGG CCGGGTCGTCCCCTACGGGGTGCGGGAGGAGGTGATCCGGGTCAAGGGGGGAAGGGAAGAGGTGCTGAAGGTGCGGGAGA CGGTCTACGGGCCCGTCATCACCGATGCCCTGCAAGCCCCCCCCAAGACCCCCATGGCCCTCCGCTGGGTGAGCCTGGAC GAGGAGGACCACATCCTCATGGCCTTCCTGGAGGTGAACCGGGCGGGGAACTGGGAGGAGTTTAAAAAGGCCCTTTTGCC CTACTCCGCCCCGAGCCAGAACTTCGTCTACGCCGACGTGGAGGGCAACATCGGCTACATCGCCCCGGGGAAGTTTCCCG TCCGCAAGGAGGGGCACACGGGGATGGTGCCGGTGCCGGGAAACGGGGAGTGGGACTGGCTGGGCTACCGGAGGCCCGAG GAGTGGCCCCAGGCCTTCAACCCCGCCAGGGGCTACCTCGTCACCGCCAACCACAAGGTGACCCCTAAGGGCTTTCCCTA CGCCCTCACCTACGACTGGGCCGAGCCCTACCGGGCGGAGCGCATAGAGGAGCTCCTCCTCGCCAAGGAGAAGCTTTCCC TGGAGGACATGAAGGCCATCCAGCAGGACCAGAAGAGCCTCCTCTACCGGGACTTCCGCCCCGTTTTGGAGCTCCTTACC CCCCTTTCCGAGGGGGCCCGGGCCTGGCGGGATAGGCTTCTCGCCTGGGACGGGACCATGGCCCCAGGCTCCGAGGAGGC CCTGGTCTTCGCCCTCTGGTACACCGAGCTCACCCGGCTTCCCCAAAGGGAGGTGGGGGAGGCCTACTGGGACGAGCCCC GCTACCTCCTTAAGGCCCTGAAGGAGGGGGACAAGAACTGCGACCAGCCGGAGACCGAGTACCGGGAGTCCTGCCTGGAC TATGCCGCCCTCGCCCTGGAACGGGCCCTGGACCGGAAGGAGGCCCTAGGGGCCAGGGCCTGGGGGGAGGTCCACCGGGC GCGCTTTCCCCACGCCGTCCTCACCCACACCCCCCTAAAACGCCTCTCCGACCGGGAGGTGGCCTTTGGCGGGGACCGGT ACACGGTGAACGTGGGGCCCTTTGACCCCGAGACCCTCGCCATGGGCCACGGGCCGAGCTACCGCCAGATCGTGGACCTT TCGGACATGGAGGGCTCCCTCTTCGTCCACCCTATGGGCCAGTCGGGCCACTTCCTCTCCCGCCACTACGCCGACCTCCT CTCCTTTTGGCGGCGCGGCGATTACCTCCCCATGCGCTTCGCGGGGGAGGGAAGGGCGCTTCTTTTGGAGCCCGGGCGCT AA
Upstream 100 bases:
>100_bases GCCCCCACCACGGCCCCGCCCGGAAGGCCCAGGCGGTGGAAGAGGAGTCCGAGGAAAACCCCGCTTAAGGAAGCGCGCAG GAGGTCCATGGGGTTATGGT
Downstream 100 bases:
>100_bases GGGGCTGCGCGTTGATTTCGCACCACGGGTTGCCCGCAATAAAGCTTGGAAAGCTTCCTTTTGGGGCCCCCACCGCGGCG AAAGCCGCGGTGGGGTGCTT
Product: penicillin acylase II
Products: NA
Alternate protein names: Cephalosporin acylase II; Penicillin acylase II; Penicillin amidase II; Penicillin acylase II small subunit; Penicillin acylase II large subunit [H]
Number of amino acids: Translated: 773; Mature: 773
Protein sequence:
>773_residues MLFPTMKRFLRGLARLLGLFLFLALLLGFSGYLYLRASLPQGEGRIALEGLSAPVEVVRDGKGVVRIRAATLKDLFFAQG FVHAQERLWQMEFQRRVGQGRLSEILGEATLPQDRFLRTWGFYRAARAAYGRLYPEEKEAVDAYAAGVNAFLASGAPLPP EFRLLGFRPEPWTGPDVLVWAKMMSYDLSGNWEEELKRHRLLARGVSPKRLLELMPPYPEDAPTILSAEDLKLPLKREEA PSALLRMAPPRFMEASNNWVVSGSRTTTGKPFLANDPHLALQAPSLWFLMALEAPGLRAIGATLPGLPGVVIGRNERIAW GVTNVGADVEDLYLLEEVEGRGYRYKGRVVPYGVREEVIRVKGGREEVLKVRETVYGPVITDALQAPPKTPMALRWVSLD EEDHILMAFLEVNRAGNWEEFKKALLPYSAPSQNFVYADVEGNIGYIAPGKFPVRKEGHTGMVPVPGNGEWDWLGYRRPE EWPQAFNPARGYLVTANHKVTPKGFPYALTYDWAEPYRAERIEELLLAKEKLSLEDMKAIQQDQKSLLYRDFRPVLELLT PLSEGARAWRDRLLAWDGTMAPGSEEALVFALWYTELTRLPQREVGEAYWDEPRYLLKALKEGDKNCDQPETEYRESCLD YAALALERALDRKEALGARAWGEVHRARFPHAVLTHTPLKRLSDREVAFGGDRYTVNVGPFDPETLAMGHGPSYRQIVDL SDMEGSLFVHPMGQSGHFLSRHYADLLSFWRRGDYLPMRFAGEGRALLLEPGR
Sequences:
>Translated_773_residues MLFPTMKRFLRGLARLLGLFLFLALLLGFSGYLYLRASLPQGEGRIALEGLSAPVEVVRDGKGVVRIRAATLKDLFFAQG FVHAQERLWQMEFQRRVGQGRLSEILGEATLPQDRFLRTWGFYRAARAAYGRLYPEEKEAVDAYAAGVNAFLASGAPLPP EFRLLGFRPEPWTGPDVLVWAKMMSYDLSGNWEEELKRHRLLARGVSPKRLLELMPPYPEDAPTILSAEDLKLPLKREEA PSALLRMAPPRFMEASNNWVVSGSRTTTGKPFLANDPHLALQAPSLWFLMALEAPGLRAIGATLPGLPGVVIGRNERIAW GVTNVGADVEDLYLLEEVEGRGYRYKGRVVPYGVREEVIRVKGGREEVLKVRETVYGPVITDALQAPPKTPMALRWVSLD EEDHILMAFLEVNRAGNWEEFKKALLPYSAPSQNFVYADVEGNIGYIAPGKFPVRKEGHTGMVPVPGNGEWDWLGYRRPE EWPQAFNPARGYLVTANHKVTPKGFPYALTYDWAEPYRAERIEELLLAKEKLSLEDMKAIQQDQKSLLYRDFRPVLELLT PLSEGARAWRDRLLAWDGTMAPGSEEALVFALWYTELTRLPQREVGEAYWDEPRYLLKALKEGDKNCDQPETEYRESCLD YAALALERALDRKEALGARAWGEVHRARFPHAVLTHTPLKRLSDREVAFGGDRYTVNVGPFDPETLAMGHGPSYRQIVDL SDMEGSLFVHPMGQSGHFLSRHYADLLSFWRRGDYLPMRFAGEGRALLLEPGR >Mature_773_residues MLFPTMKRFLRGLARLLGLFLFLALLLGFSGYLYLRASLPQGEGRIALEGLSAPVEVVRDGKGVVRIRAATLKDLFFAQG FVHAQERLWQMEFQRRVGQGRLSEILGEATLPQDRFLRTWGFYRAARAAYGRLYPEEKEAVDAYAAGVNAFLASGAPLPP EFRLLGFRPEPWTGPDVLVWAKMMSYDLSGNWEEELKRHRLLARGVSPKRLLELMPPYPEDAPTILSAEDLKLPLKREEA PSALLRMAPPRFMEASNNWVVSGSRTTTGKPFLANDPHLALQAPSLWFLMALEAPGLRAIGATLPGLPGVVIGRNERIAW GVTNVGADVEDLYLLEEVEGRGYRYKGRVVPYGVREEVIRVKGGREEVLKVRETVYGPVITDALQAPPKTPMALRWVSLD EEDHILMAFLEVNRAGNWEEFKKALLPYSAPSQNFVYADVEGNIGYIAPGKFPVRKEGHTGMVPVPGNGEWDWLGYRRPE EWPQAFNPARGYLVTANHKVTPKGFPYALTYDWAEPYRAERIEELLLAKEKLSLEDMKAIQQDQKSLLYRDFRPVLELLT PLSEGARAWRDRLLAWDGTMAPGSEEALVFALWYTELTRLPQREVGEAYWDEPRYLLKALKEGDKNCDQPETEYRESCLD YAALALERALDRKEALGARAWGEVHRARFPHAVLTHTPLKRLSDREVAFGGDRYTVNVGPFDPETLAMGHGPSYRQIVDL SDMEGSLFVHPMGQSGHFLSRHYADLLSFWRRGDYLPMRFAGEGRALLLEPGR
Specific function: Unknown
COG id: COG2366
COG function: function code R; Protein related to penicillin acylase
Gene ontology:
Cell location: Cytoplasmic
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the peptidase S45 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR014395 - InterPro: IPR002692 [H]
Pfam domain/function: PF01804 Penicil_amidase [H]
EC number: =3.5.1.11 [H]
Molecular weight: Translated: 87378; Mature: 87378
Theoretical pI: Translated: 6.86; Mature: 6.86
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.6 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 2.6 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLFPTMKRFLRGLARLLGLFLFLALLLGFSGYLYLRASLPQGEGRIALEGLSAPVEVVRD CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHC GKGVVRIRAATLKDLFFAQGFVHAQERLWQMEFQRRVGQGRLSEILGEATLPQDRFLRTW CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHH GFYRAARAAYGRLYPEEKEAVDAYAAGVNAFLASGAPLPPEFRLLGFRPEPWTGPDVLVW HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHH AKMMSYDLSGNWEEELKRHRLLARGVSPKRLLELMPPYPEDAPTILSAEDLKLPLKREEA HHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCC PSALLRMAPPRFMEASNNWVVSGSRTTTGKPFLANDPHLALQAPSLWFLMALEAPGLRAI HHHHHHCCCCHHHCCCCCEEEECCCCCCCCCEECCCCCEEEECCCEEEEEEECCCCCHHH GATLPGLPGVVIGRNERIAWGVTNVGADVEDLYLLEEVEGRGYRYKGRVVPYGVREEVIR HCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCEECCCHHHHHHH VKGGREEVLKVRETVYGPVITDALQAPPKTPMALRWVSLDEEDHILMAFLEVNRAGNWEE HCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHH FKKALLPYSAPSQNFVYADVEGNIGYIAPGKFPVRKEGHTGMVPVPGNGEWDWLGYRRPE HHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCH EWPQAFNPARGYLVTANHKVTPKGFPYALTYDWAEPYRAERIEELLLAKEKLSLEDMKAI HHHHHCCCCCCEEEECCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHH QQDQKSLLYRDFRPVLELLTPLSEGARAWRDRLLAWDGTMAPGSEEALVFALWYTELTRL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEEHHHHHHC PQREVGEAYWDEPRYLLKALKEGDKNCDQPETEYRESCLDYAALALERALDRKEALGARA CHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH WGEVHRARFPHAVLTHTPLKRLSDREVAFGGDRYTVNVGPFDPETLAMGHGPSYRQIVDL HHHHHHHCCCCHHHHCCHHHHCCCCCEEECCCEEEEEECCCCCCCEEECCCCCCCEEEEC SDMEGSLFVHPMGQSGHFLSRHYADLLSFWRRGDYLPMRFAGEGRALLLEPGR CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCC >Mature Secondary Structure MLFPTMKRFLRGLARLLGLFLFLALLLGFSGYLYLRASLPQGEGRIALEGLSAPVEVVRD CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCCCHHHHHC GKGVVRIRAATLKDLFFAQGFVHAQERLWQMEFQRRVGQGRLSEILGEATLPQDRFLRTW CCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHH GFYRAARAAYGRLYPEEKEAVDAYAAGVNAFLASGAPLPPEFRLLGFRPEPWTGPDVLVW HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHH AKMMSYDLSGNWEEELKRHRLLARGVSPKRLLELMPPYPEDAPTILSAEDLKLPLKREEA HHHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEECCCCCCCCCCCCCC PSALLRMAPPRFMEASNNWVVSGSRTTTGKPFLANDPHLALQAPSLWFLMALEAPGLRAI HHHHHHCCCCHHHCCCCCEEEECCCCCCCCCEECCCCCEEEECCCEEEEEEECCCCCHHH GATLPGLPGVVIGRNERIAWGVTNVGADVEDLYLLEEVEGRGYRYKGRVVPYGVREEVIR HCCCCCCCEEEEECCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEECCEECCCHHHHHHH VKGGREEVLKVRETVYGPVITDALQAPPKTPMALRWVSLDEEDHILMAFLEVNRAGNWEE HCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCHHH FKKALLPYSAPSQNFVYADVEGNIGYIAPGKFPVRKEGHTGMVPVPGNGEWDWLGYRRPE HHHHHCCCCCCCCCEEEEEECCCEEEECCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCH EWPQAFNPARGYLVTANHKVTPKGFPYALTYDWAEPYRAERIEELLLAKEKLSLEDMKAI HHHHHCCCCCCEEEECCCEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHHH QQDQKSLLYRDFRPVLELLTPLSEGARAWRDRLLAWDGTMAPGSEEALVFALWYTELTRL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEEHHHHHHC PQREVGEAYWDEPRYLLKALKEGDKNCDQPETEYRESCLDYAALALERALDRKEALGARA CHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH WGEVHRARFPHAVLTHTPLKRLSDREVAFGGDRYTVNVGPFDPETLAMGHGPSYRQIVDL HHHHHHHCCCCHHHHCCHHHHCCCCCEEECCCEEEEEECCCCCCCEEECCCCCCCEEEEC SDMEGSLFVHPMGQSGHFLSRHYADLLSFWRRGDYLPMRFAGEGRALLLEPGR CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEEECCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 3680178 [H]