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The map label for this gene is pqqL [C]

Identifier: 54295511

GI number: 54295511

Start: 2964893

End: 2966218

Strand: Direct

Name: pqqL [C]

Synonym: lpl2598

Alternate gene names: 54295511

Gene position: 2964893-2966218 (Clockwise)

Preceding gene: 54295506

Following gene: 54295512

Centisome position: 88.62

GC content: 40.72

Gene sequence:

>1326_bases
GTGCACAAATTACTCATTTCTCTTATGATGCTACTCTCATTTCAGGCTTTTAGCCAAGTCCAGGAGTATACGTTAAACAA
TGGTTTAAAAGTACTGGTAAAAGAAGATCATCGAGCTCCAGTCGTAGTATCCATGATTTGGTATAACGTGGGTTCAGCAG
ATGAGCCTGTAGGCATCACAGGTGTTTCTCATGCCATAGAACACATGATGTTTAAAGGAACTTCCAAATACCCGGTAGGG
GTATTTTCCAAAACAATTGCTGCATTGGGAGGTCAGGAAAATGCTTTTACAAACAATGATTATACCGCCTATTATGAAAA
ATTAGATGCTGATCATCTGGCTACAAGCTTCGAATTGGAAGCCGATCGCATGAATAATTTACAGCTTAATAGTGAAGAAT
TCGCTAAAGAAATTAAAGTCATTCAAGAGGAAAGACGTTTACGTACTGACAATAACCCGCAGGCACTTGCTTTCGAACGT
TTTCTGGCCACAGCGCATCTTACAGCACCATACAATCACCCGGTGATAGGATGGATGAATGATTTGAAACAAATGAAAGT
AGAGGATTTAAAAAAATGGTACGAAAGTTATTACGCACCAAATAATGCCACCTTGGTAGTAGTAGGCGATGTGAATCCTG
AGAAAGTACATGCCTTGGCTGAACGTTATTTCGGTTCAATAGCCAAACGTCCCATAGCGTCTCGGAAACCCCAGCAAGAA
CCCTCAGCGCTTGGGAAAAAAATGGTTTACATTAACGCGCCAGCGAAATTGCCATTACTGTTAATTGGCTATACTGTACC
TAGTGTAAAAACTGCTAAAAATAACTGGGAACCTTACGCCTTGGAAATTATCGCCGGGATACTTGATGCCGGGGAAAGTG
CGCGCTTTGCCAAACACCTGGTGCGAGGCAATCAAGTAGCCACTGGTGCAGAAGCCTATTATAACCTCTATTCAAGGTAC
CAAAGCCAATTTATTGTCTATGGGGCGCCTAGCCAAGATCATCAAATAAAAGATCTGGAAAAGGCATTAATTACGGAATT
GGAAGCCTTAAAAAAAGCGCCTGTTAGCAATCAGGAATTACAAAGGGTTAAAAATCAAATCATAGCACAAAAAACTTTTG
AAAAAGATTCTATTTTTGGTCAGGCCATGGAGCTGGGATTGTTACAAACAATAGGTCTGGGTTGGAAAAATACGGAAACA
TACACCAAAGCCATCAATGAAATAACCCCCGAGCAAATTCAGCAAGTTGCGCAACGATATTTTCAAGAAAATAACATGAC
TGTTGCAGAATTAAAGCCAATCAGGCAAGAAGAGGTAAGACCATGA

Upstream 100 bases:

>100_bases
GGTTCGGAATTTTGATTTCGTTTAAACCATTTAATCATTTTAGTGTACAATTCCTTAAAAATATGAAATTCTATCATCTT
TTTAGCTTTGAGGTGACATT

Downstream 100 bases:

>100_bases
GTGTTTTAAGAGCTTTTATCATTTCGTTTAGTGTAATTTTTTCTCACAATCTATTCGCCAATTCATTCAAAACTGAAAAA
TGGCAGACTAAAAATGGGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MHKLLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGITGVSHAIEHMMFKGTSKYPVG
VFSKTIAALGGQENAFTNNDYTAYYEKLDADHLATSFELEADRMNNLQLNSEEFAKEIKVIQEERRLRTDNNPQALAFER
FLATAHLTAPYNHPVIGWMNDLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAERYFGSIAKRPIASRKPQQE
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHLVRGNQVATGAEAYYNLYSRY
QSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQELQRVKNQIIAQKTFEKDSIFGQAMELGLLQTIGLGWKNTET
YTKAINEITPEQIQQVAQRYFQENNMTVAELKPIRQEEVRP

Sequences:

>Translated_441_residues
MHKLLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGITGVSHAIEHMMFKGTSKYPVG
VFSKTIAALGGQENAFTNNDYTAYYEKLDADHLATSFELEADRMNNLQLNSEEFAKEIKVIQEERRLRTDNNPQALAFER
FLATAHLTAPYNHPVIGWMNDLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAERYFGSIAKRPIASRKPQQE
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHLVRGNQVATGAEAYYNLYSRY
QSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQELQRVKNQIIAQKTFEKDSIFGQAMELGLLQTIGLGWKNTET
YTKAINEITPEQIQQVAQRYFQENNMTVAELKPIRQEEVRP
>Mature_441_residues
MHKLLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGITGVSHAIEHMMFKGTSKYPVG
VFSKTIAALGGQENAFTNNDYTAYYEKLDADHLATSFELEADRMNNLQLNSEEFAKEIKVIQEERRLRTDNNPQALAFER
FLATAHLTAPYNHPVIGWMNDLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAERYFGSIAKRPIASRKPQQE
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHLVRGNQVATGAEAYYNLYSRY
QSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQELQRVKNQIIAQKTFEKDSIFGQAMELGLLQTIGLGWKNTET
YTKAINEITPEQIQQVAQRYFQENNMTVAELKPIRQEEVRP

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI46593007, Length=215, Percent_Identity=27.906976744186, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI94538354, Length=222, Percent_Identity=28.8288288288288, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI155969707, Length=214, Percent_Identity=25.2336448598131, Blast_Score=71, Evalue=3e-12,
Organism=Escherichia coli, GI1787770, Length=424, Percent_Identity=24.0566037735849, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI2367164, Length=224, Percent_Identity=26.3392857142857, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17553678, Length=232, Percent_Identity=26.2931034482759, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71999683, Length=204, Percent_Identity=25.4901960784314, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71994338, Length=244, Percent_Identity=24.5901639344262, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146566, Length=244, Percent_Identity=24.5901639344262, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25146563, Length=244, Percent_Identity=24.5901639344262, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI32566665, Length=244, Percent_Identity=24.5901639344262, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI72001443, Length=244, Percent_Identity=24.5901639344262, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=421, Percent_Identity=22.3277909738717, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6323421, Length=303, Percent_Identity=21.7821782178218, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI21357875, Length=423, Percent_Identity=24.5862884160757, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24646943, Length=423, Percent_Identity=24.5862884160757, Blast_Score=96, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24667786, Length=222, Percent_Identity=27.027027027027, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 49864; Mature: 49864

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKLLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGIT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHCCCCCCCCCCCCC
GVSHAIEHMMFKGTSKYPVGVFSKTIAALGGQENAFTNNDYTAYYEKLDADHLATSFELE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHEEEC
ADRMNNLQLNSEEFAKEIKVIQEERRLRTDNNPQALAFERFLATAHLTAPYNHPVIGWMN
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
DLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAERYFGSIAKRPIASRKPQQE
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHL
HHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VRGNQVATGAEAYYNLYSRYQSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQEL
HCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
QRVKNQIIAQKTFEKDSIFGQAMELGLLQTIGLGWKNTETYTKAINEITPEQIQQVAQRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
FQENNMTVAELKPIRQEEVRP
HHHCCCCHHHHCCCHHHCCCC
>Mature Secondary Structure
MHKLLISLMMLLSFQAFSQVQEYTLNNGLKVLVKEDHRAPVVVSMIWYNVGSADEPVGIT
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHCCCCCCCCCCCCC
GVSHAIEHMMFKGTSKYPVGVFSKTIAALGGQENAFTNNDYTAYYEKLDADHLATSFELE
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHEEEC
ADRMNNLQLNSEEFAKEIKVIQEERRLRTDNNPQALAFERFLATAHLTAPYNHPVIGWMN
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHH
DLKQMKVEDLKKWYESYYAPNNATLVVVGDVNPEKVHALAERYFGSIAKRPIASRKPQQE
HHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSALGKKMVYINAPAKLPLLLIGYTVPSVKTAKNNWEPYALEIIAGILDAGESARFAKHL
HHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHH
VRGNQVATGAEAYYNLYSRYQSQFIVYGAPSQDHQIKDLEKALITELEALKKAPVSNQEL
HCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHH
QRVKNQIIAQKTFEKDSIFGQAMELGLLQTIGLGWKNTETYTKAINEITPEQIQQVAQRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHH
FQENNMTVAELKPIRQEEVRP
HHHCCCCHHHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]