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The map label for this gene is yfhR [C]

Identifier: 54295441

GI number: 54295441

Start: 2882982

End: 2883779

Strand: Direct

Name: yfhR [C]

Synonym: lpl2527

Alternate gene names: 54295441

Gene position: 2882982-2883779 (Clockwise)

Preceding gene: 54295440

Following gene: 54295458

Centisome position: 86.17

GC content: 38.85

Gene sequence:

>798_bases
ATGCTGAAACAAATTGTGCTAACCGGCCTAGTTATTATAGGGATTGTCATTACGCTAATGTACTTATTTCAGCGTCACCT
CATTTATTTCCCTAATAGACATACCCCAAAGTTGGAAGATTACAATGCATCGGATATGAAAGTAGTTTCCTTACGTACAA
AAGATAATTTACATTTAAAATCCTGGTATAAACCTGCAAGCGAGCATCGCCCTACAATACTCTATTTGCATGGGAATGCA
GGCCATATTGGTTACAGAATGCCATTGGTTCGTGAATTTATTGACGCTGGTTTAGGAGTATTTTTATTAGAATATCGTGG
TTATGGAGGCAATCCGGGCAAACCTGGCGAGAAAGGTCTTTATGAAGATGGAGAAACAGCCATTGAATTTTTAATTCAAC
ATGGTGTGCCATCAAAGCGCGTGATTCTATATGGGGAATCCATAGGTACTGGCGTAGCAACTCACCTTGCCACAAAATAC
CTGGTTTGTGCGGTTATACTTCAATCACCCTTTACATCACTAACCAGGCTTGCCCAGTATCACTACCCATTGAACTTCCT
TAAACCCTGGGATCAATATAATTCACTTGCCCGTATGAAAAAAATTAATGCCCCCATTCTGGTTTTGCATGGAAAGTTGG
ATCAGATAGTACCGTATCAAGAGGGCTTAAATGTTTTTAATGAAGCCAACGAACCTAAAAAAATGATTTCTTTTGACGAC
AAAGAACATAATGATTTGTGGAGCGCTGATAATTTTTCGAGGGAAATTATTCAATTTGCTTTAAACCAGTGTTCCTAG

Upstream 100 bases:

>100_bases
TTTTGAGGCAATTCGCCCATCATCGATATTGGCTTCCAATCGATTAAGGTGCATTATAATCAAATTAATACAATATATTT
AAATCCTTCTTAAGGTGATC

Downstream 100 bases:

>100_bases
CTTTTGTGGATAGTTCATTATTAACGCATTTTCATCATCGGCGTTATTATTAAACTCAATCTTCCATTTCCGCAAAGGCC
ATTGAAAATCTCCTTTCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLKSWYKPASEHRPTILYLHGNA
GHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGLYEDGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKY
LVCAVILQSPFTSLTRLAQYHYPLNFLKPWDQYNSLARMKKINAPILVLHGKLDQIVPYQEGLNVFNEANEPKKMISFDD
KEHNDLWSADNFSREIIQFALNQCS

Sequences:

>Translated_265_residues
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLKSWYKPASEHRPTILYLHGNA
GHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGLYEDGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKY
LVCAVILQSPFTSLTRLAQYHYPLNFLKPWDQYNSLARMKKINAPILVLHGKLDQIVPYQEGLNVFNEANEPKKMISFDD
KEHNDLWSADNFSREIIQFALNQCS
>Mature_265_residues
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLKSWYKPASEHRPTILYLHGNA
GHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGLYEDGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKY
LVCAVILQSPFTSLTRLAQYHYPLNFLKPWDQYNSLARMKKINAPILVLHGKLDQIVPYQEGLNVFNEANEPKKMISFDD
KEHNDLWSADNFSREIIQFALNQCS

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI49355781, Length=266, Percent_Identity=29.3233082706767, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI71051602, Length=180, Percent_Identity=33.8888888888889, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI71051600, Length=193, Percent_Identity=32.6424870466321, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI151301175, Length=215, Percent_Identity=31.1627906976744, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI194306564, Length=182, Percent_Identity=31.3186813186813, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI194306562, Length=182, Percent_Identity=31.3186813186813, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI32451492, Length=210, Percent_Identity=33.3333333333333, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI109689718, Length=202, Percent_Identity=31.6831683168317, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI32528310, Length=215, Percent_Identity=33.4883720930233, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI24308097, Length=202, Percent_Identity=31.6831683168317, Blast_Score=90, Evalue=2e-18,
Organism=Escherichia coli, GI226510965, Length=272, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71988362, Length=184, Percent_Identity=33.1521739130435, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25143554, Length=157, Percent_Identity=31.2101910828025, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17566318, Length=189, Percent_Identity=29.1005291005291, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17532877, Length=203, Percent_Identity=26.6009852216749, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71985392, Length=203, Percent_Identity=25.615763546798, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71985387, Length=220, Percent_Identity=24.0909090909091, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324009, Length=280, Percent_Identity=30.7142857142857, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17137566, Length=277, Percent_Identity=29.6028880866426, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI281362521, Length=231, Percent_Identity=28.1385281385281, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281362519, Length=231, Percent_Identity=28.1385281385281, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI28571878, Length=231, Percent_Identity=28.1385281385281, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24655464, Length=190, Percent_Identity=27.8947368421053, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24655467, Length=190, Percent_Identity=27.8947368421053, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 30219; Mature: 30219

Theoretical pI: Translated: 8.86; Mature: 8.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCCCCHH
SWYKPASEHRPTILYLHGNAGHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGL
HHCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCC
YEDGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKYLVCAVILQSPFTSLTRLAQY
CCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
HYPLNFLKPWDQYNSLARMKKINAPILVLHGKLDQIVPYQEGLNVFNEANEPKKMISFDD
HCCCHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHCCCCCHHHHCCCC
KEHNDLWSADNFSREIIQFALNQCS
CCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKQIVLTGLVIIGIVITLMYLFQRHLIYFPNRHTPKLEDYNASDMKVVSLRTKDNLHLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCEEEEEEECCCCCCHH
SWYKPASEHRPTILYLHGNAGHIGYRMPLVREFIDAGLGVFLLEYRGYGGNPGKPGEKGL
HHCCCHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCHHEEEEEECCCCCCCCCCCCCCC
YEDGETAIEFLIQHGVPSKRVILYGESIGTGVATHLATKYLVCAVILQSPFTSLTRLAQY
CCCHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
HYPLNFLKPWDQYNSLARMKKINAPILVLHGKLDQIVPYQEGLNVFNEANEPKKMISFDD
HCCCHHCCCHHHHHHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHCCCCCHHHHCCCC
KEHNDLWSADNFSREIIQFALNQCS
CCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]