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The map label for this gene is ampC [H]

Identifier: 54295253

GI number: 54295253

Start: 2664785

End: 2665864

Strand: Direct

Name: ampC [H]

Synonym: lpl2336

Alternate gene names: 54295253

Gene position: 2664785-2665864 (Clockwise)

Preceding gene: 54295251

Following gene: 54295254

Centisome position: 79.65

GC content: 37.22

Gene sequence:

>1080_bases
ATGAAATCAAAATACATTAACTTATGCTTTTTTTCACTCATTTTATGGTTTGGCAGTCCAATTCTTTTGGCACAACCATC
CAGGCTGGATAATCTAATTAATCAACTGGTTCAACCATTTATTTATGCACATCAGACTCCCGGGTTAGCCATTGCCATTT
ATTATAATGGAAAGGATTATTATTATAATTTTGGATTTGCTGACCGGAAAAGTAAGAAGCCAGTGACTAAAAATACTATT
TTTGAATTGGCATCGATTACCAAAATATTCATTAGCACTCTTATAGCACTGGAAGTTCAGAAAGGAAAATTGAATGTAAC
AGATTATGCCGTTCAATATACACCTGAACTTTCAAAAACCAATGGACTACCAATTGACAGGGTTCAAATTGTACATCTGG
CGACTCACACAGCAAGCTTTCCCAAACAAATGGAGCAATTTGGTGTTAATAAAGGCAATATACAGGCTTTCTTTGCCCAT
CTTAAAACATGGCGTCCTCCAGTAAAAACAGGAACTCATTATAAATATTCCAATATTGGTTTTGGGTATTTGGGATACAT
ATTGGAAAACGCCTCAAACGAGACTTTACCTAATCTGTTAAAATCGAATATTACCAAGCCATTGGGAATGTCCCATACTT
TTTTTAATGTACCAGAAAGTCTGGCTAACTATGAAGCTCAAGGTTATCGACCTAAAAACAAGCCAGCACCTTATTATAGA
CCTGCCAATTTTCTAGGTGGAGGTGCTTTGCGATCTTCTGCAGCTGACATGCTGGTATTTTTAAAAGCAAATTTAGGAAT
TCAACCTGGCACCACATCACCAACATTGCTTTCTGCAATGCAGTATGCCCAACAACCATTTTTTGAAGTCAACCCAAATT
TTGTTATGGGATTAGGTTGGCAAAGAGTGAAAAGAGGGAGGCAGATTGTGATCACTAAAAATGGAGCAAATCAGGGATTT
AGCACCTTTATTGGTTTTTCACCTGCAAAAAAACTGGGAGTCGTCGTATTAATCAATCAGGCAAGGGGCAAGGCAACCTT
GCTGGGAAACCAAATTCTTAATAGTCTGCTTAGATTATAG

Upstream 100 bases:

>100_bases
TGGAGCTCTTACATAGCCAGGATAGAATCACTGCAACATGACCTGATGATGCAAAATAAAGAAAAGATAATTATTATATT
TTTCCAAAAAGACATTAATC

Downstream 100 bases:

>100_bases
CTTAAAGGACTATTTTTAAGCGTAGACTCATGGGCATTGACAATCAAAATGTCGTGCAACATGATTATCCTTGACCCTAT
TCTCTGTGCGTCTTGACTTA

Product: beta-lactamase

Products: NA

Alternate protein names: Cephalosporinase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKSKYINLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLIALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAH
LKTWRPPVKTGTHYKYSNIGFGYLGYILENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYR
PANFLGGGALRSSAADMLVFLKANLGIQPGTTSPTLLSAMQYAQQPFFEVNPNFVMGLGWQRVKRGRQIVITKNGANQGF
STFIGFSPAKKLGVVVLINQARGKATLLGNQILNSLLRL

Sequences:

>Translated_359_residues
MKSKYINLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLIALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAH
LKTWRPPVKTGTHYKYSNIGFGYLGYILENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYR
PANFLGGGALRSSAADMLVFLKANLGIQPGTTSPTLLSAMQYAQQPFFEVNPNFVMGLGWQRVKRGRQIVITKNGANQGF
STFIGFSPAKKLGVVVLINQARGKATLLGNQILNSLLRL
>Mature_359_residues
MKSKYINLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDYYYNFGFADRKSKKPVTKNTI
FELASITKIFISTLIALEVQKGKLNVTDYAVQYTPELSKTNGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAH
LKTWRPPVKTGTHYKYSNIGFGYLGYILENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYR
PANFLGGGALRSSAADMLVFLKANLGIQPGTTSPTLLSAMQYAQQPFFEVNPNFVMGLGWQRVKRGRQIVITKNGANQGF
STFIGFSPAKKLGVVVLINQARGKATLLGNQILNSLLRL

Specific function: This protein is a serine beta-lactamase with a substrate specificity for cephalosporins [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-C beta-lactamase family [H]

Homologues:

Organism=Escherichia coli, GI1790593, Length=375, Percent_Identity=27.7333333333333, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1786574, Length=356, Percent_Identity=22.752808988764, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001586
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 40048; Mature: 40048

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSKYINLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDY
CCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
YYNFGFADRKSKKPVTKNTIFELASITKIFISTLIALEVQKGKLNVTDYAVQYTPELSKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEEEEECCCCCCC
NGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAHLKTWRPPVKTGTHYKYSNIG
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCC
FGYLGYILENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYR
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCC
PANFLGGGALRSSAADMLVFLKANLGIQPGTTSPTLLSAMQYAQQPFFEVNPNFVMGLGW
CCCCCCCHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEECCH
QRVKRGRQIVITKNGANQGFSTFIGFSPAKKLGVVVLINQARGKATLLGNQILNSLLRL
HHHHCCCEEEEEECCCCCCCHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSKYINLCFFSLILWFGSPILLAQPSRLDNLINQLVQPFIYAHQTPGLAIAIYYNGKDY
CCCCHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEE
YYNFGFADRKSKKPVTKNTIFELASITKIFISTLIALEVQKGKLNVTDYAVQYTPELSKT
EEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEEEEEEEECCCCCCC
NGLPIDRVQIVHLATHTASFPKQMEQFGVNKGNIQAFFAHLKTWRPPVKTGTHYKYSNIG
CCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCC
FGYLGYILENASNETLPNLLKSNITKPLGMSHTFFNVPESLANYEAQGYRPKNKPAPYYR
HHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHCCCHHHHCCCCCCCCCCCCCCCCCC
PANFLGGGALRSSAADMLVFLKANLGIQPGTTSPTLLSAMQYAQQPFFEVNPNFVMGLGW
CCCCCCCHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEECCCCEEEECCH
QRVKRGRQIVITKNGANQGFSTFIGFSPAKKLGVVVLINQARGKATLLGNQILNSLLRL
HHHHCCCEEEEEECCCCCCCHHHHCCCCHHHCCEEEEEECCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9066104 [H]