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The map label for this gene is comF [H]

Identifier: 54295172

GI number: 54295172

Start: 2570995

End: 2571699

Strand: Direct

Name: comF [H]

Synonym: lpl2252

Alternate gene names: 54295172

Gene position: 2570995-2571699 (Clockwise)

Preceding gene: 54295170

Following gene: 54295175

Centisome position: 76.85

GC content: 38.3

Gene sequence:

>705_bases
GTGCTCCAAAAATTCTTAAGTATAACACAGAACTTACGTTTACCTTCAATATGCACTCTTTGCAACCAGTTCCACAAAAG
CCAACTTGCAGTTTGCTCTAATTGCATGGAGTTTATGAAACAACTTGGATCATGCTGTCAGTACTGTGCCTACCCCCTTT
CTGATGATACGTATCTGGTTTGTGGTCAATGCGTTAGAAAAAGGCCCTCCTTTGATAGTGCTTATATAGCGTATCGTTTT
GAAGAGCCTCTGCGTAGTTTAATACATCAGTTTAAATACCATAATGGCCTTTATCTGGCCTCGTTTCTAAAGCAATTACT
TCTTAATGCCTTACCCAAAAGCGCATTGAAACCAGATTGTCTAATTCCCGTTCCCATGCATCCCAAACGATTAAAACGAA
GGGGATTTAACCAGGCTGCTGTATTAACCAGATTATTAGCTCGTCAATTAAACATCCCTTATGATTTATATTATTGTCAA
AAAATAATCAATACCGCTTCACAAGCTAACCTTGATGGAGAGCAACGAAGAAAAAATTTACGTCATGCTTTTTATGTACC
ACATGTAACTTATGAACACGTCATGATTGTTGATGACTTATTAACCACAGGCAGCACAGCCAATGAAATGGCACATACAT
TAAAAAATGCCGGAGTTAAGAGAGTAGATATATGTTGTTGTGCGCGGGCTGTAACTAAGAACTAA

Upstream 100 bases:

>100_bases
CTCATAGTCATCGGCATGCTTGCTAAATGCCTTGCTTATTTCATTGTTGACCGTCATTATAAAGACCAGGGAAAAATTAA
ATGCTGGAAATCCAACTATC

Downstream 100 bases:

>100_bases
GTCAGCCCGTTCCTATGAGTCCACTGTCAATGGTGTAAATATCGATTCAAATCATTCATTAATAAATGCACCAACAAAAC
ACAAAATAGAATAATCATCA

Product: hypothetical protein

Products: NA

Alternate protein names: DNA transformation protein ComF; Protein COM101A [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLQKFLSITQNLRLPSICTLCNQFHKSQLAVCSNCMEFMKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDSAYIAYRF
EEPLRSLIHQFKYHNGLYLASFLKQLLLNALPKSALKPDCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLNIPYDLYYCQ
KIINTASQANLDGEQRRKNLRHAFYVPHVTYEHVMIVDDLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN

Sequences:

>Translated_234_residues
MLQKFLSITQNLRLPSICTLCNQFHKSQLAVCSNCMEFMKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDSAYIAYRF
EEPLRSLIHQFKYHNGLYLASFLKQLLLNALPKSALKPDCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLNIPYDLYYCQ
KIINTASQANLDGEQRRKNLRHAFYVPHVTYEHVMIVDDLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN
>Mature_234_residues
MLQKFLSITQNLRLPSICTLCNQFHKSQLAVCSNCMEFMKQLGSCCQYCAYPLSDDTYLVCGQCVRKRPSFDSAYIAYRF
EEPLRSLIHQFKYHNGLYLASFLKQLLLNALPKSALKPDCLIPVPMHPKRLKRRGFNQAAVLTRLLARQLNIPYDLYYCQ
KIINTASQANLDGEQRRKNLRHAFYVPHVTYEHVMIVDDLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN

Specific function: Involved in transformation (competence for DNA uptake) [H]

COG id: COG1040

COG function: function code R; Predicted amidophosphoribosyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ComF/GntX family [H]

Homologues:

Organism=Escherichia coli, GI87082263, Length=227, Percent_Identity=33.0396475770925, Blast_Score=106, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005222
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: NA

Molecular weight: Translated: 26803; Mature: 26803

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

6.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
8.5 %Cys+Met (Translated Protein)
6.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
8.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKFLSITQNLRLPSICTLCNQFHKSQLAVCSNCMEFMKQLGSCCQYCAYPLSDDTYLV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEH
CGQCVRKRPSFDSAYIAYRFEEPLRSLIHQFKYHNGLYLASFLKQLLLNALPKSALKPDC
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCC
LIPVPMHPKRLKRRGFNQAAVLTRLLARQLNIPYDLYYCQKIINTASQANLDGEQRRKNL
EECCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
RHAFYVPHVTYEHVMIVDDLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN
HHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MLQKFLSITQNLRLPSICTLCNQFHKSQLAVCSNCMEFMKQLGSCCQYCAYPLSDDTYLV
CHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEH
CGQCVRKRPSFDSAYIAYRFEEPLRSLIHQFKYHNGLYLASFLKQLLLNALPKSALKPDC
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHCCCCC
LIPVPMHPKRLKRRGFNQAAVLTRLLARQLNIPYDLYYCQKIINTASQANLDGEQRRKNL
EECCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
RHAFYVPHVTYEHVMIVDDLLTTGSTANEMAHTLKNAGVKRVDICCCARAVTKN
HHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1916268; 1856167; 7542800 [H]