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The map label for this gene is asnC [H]

Identifier: 54295128

GI number: 54295128

Start: 2521990

End: 2523393

Strand: Direct

Name: asnC [H]

Synonym: lpl2208

Alternate gene names: 54295128

Gene position: 2521990-2523393 (Clockwise)

Preceding gene: 54295126

Following gene: 54295135

Centisome position: 75.38

GC content: 43.02

Gene sequence:

>1404_bases
ATGACAGAAGTCTTTACTATAAAACAATGTCTCGACGGCGAAATCAGTATTGATGAAACCGTTACGGTAAGAGGATGGGT
GAAAACCCGAAGAGATTCAAAAGCTGGCTTGTCTTTCATCAGCCTTCATGATGGCTCCTGCTTTTCTCCCATACAAATCG
TCGCTACCGATCAGTTATCCAACTACCAAAAAGAGGTTACAAAATTAACTGCTGGCTGTTCAATGATAGCGACTGGAAAA
TTGGTGGCATCGCAAGGAAAAGGGCAATTTTTTGAAATCCAGGCCGAATCCATTGAAGTGGTGGGATGGGTTGAAAATCC
AGATACGTACCCTATCCAAGCCAAGCGCCATACTCTTGAATTTTTAAGAGAAGTGGCTCACTTGCGCCCCAGAACCAATA
CCATAAGCGCTGTCACCAGAGTGCGCCATTCATTGGCACAAGCCATTCACCGTTTTTATCATGAACAAGGCTTTTTTTGG
GTTCATACACCTATCATTACTGCCAGCGACTGTGAAGGGGCAGGAGAAATGTTCAGGGTATCTACTCTGGATTTATTAAA
TATACCTAAAAATGATAAAGGACAAATTGATTTCAGTAAGGATTTTTTTGGCAGAGAAACATTCTTAACTGTTTCTGGCC
AATTAAATGTGGAAGCCTATTGTATGGCAATGTCCAAAGTATACACATTTGGACCAACATTTCGAGCTGAAAACTCCAAT
ACAAGCCGACATTTGGCAGAATTCTGGATGATCGAACCAGAAATCGCTTTTGCAAATCTCGAAGACATTTGTAAACTCAG
CCAAAATATGCTGCGTTATCTCTGTAAAACTGTTCTTGAAGAGCGTTCAGATGATATGGACTTTTTCAACCAGTTTGTTG
CTCCAGGATGCATAGAGCGCATGGAACATATTGCGGATTCTGAATTTGAAATTATGACCTATACCGATGCAATCAAAGCA
CTTGAGGCGAGTGAGCAAAAGTTTGAATTTCCAGTGAGCTGGGGGCTGGATCTGCAATCAGAGCATGAACGTTACCTGGC
TGAAGTGCTTTGCAAAAAGCCTGTCATTGTGACAAATTACCCGCAAGAAATTAAAGGCTTTTACATGCGCCTTAATGACG
ATGGAAAAACGGTAGCCGCTATGGATGTTTTAGCTCCAGGCATTGGAGAGATTATCGGCGGCAGCCAACGCGAAGAGCGA
TTGGAAATACTGGATAGACGCATGGACGAGTGCAACCTAAATAAAGAACATTACCAATGGTATAGAGACTTGCGTCGTTA
TGGCACTGTGCCTCATGCCGGATTTGGCTTGGGCTTTGAGCGCTTGATCAGCTATGTTACAGGGGTATCAAATGTGCGAG
ATGTAATACCATTCCCTCGCACACCAGGCCATGCGGATTATTAA

Upstream 100 bases:

>100_bases
AGGGTTTAGGAAATACTACAAACGAGAGAAAATCAATCCCTCGAAGGATTGGAATATTTCCTAAACCCTGAATCAATCGT
TTTCGATTTTGGAGTATATA

Downstream 100 bases:

>100_bases
ATCGATAAGGCGCTTAAAGAATCTTCCTCAACTTCAGCTGTTTGTTGTTGAGGTTGATTCCCCTCAGACAGCAATCGCCG
TCTATTTCTTGGCGAAAATA

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MTEVFTIKQCLDGEISIDETVTVRGWVKTRRDSKAGLSFISLHDGSCFSPIQIVATDQLSNYQKEVTKLTAGCSMIATGK
LVASQGKGQFFEIQAESIEVVGWVENPDTYPIQAKRHTLEFLREVAHLRPRTNTISAVTRVRHSLAQAIHRFYHEQGFFW
VHTPIITASDCEGAGEMFRVSTLDLLNIPKNDKGQIDFSKDFFGRETFLTVSGQLNVEAYCMAMSKVYTFGPTFRAENSN
TSRHLAEFWMIEPEIAFANLEDICKLSQNMLRYLCKTVLEERSDDMDFFNQFVAPGCIERMEHIADSEFEIMTYTDAIKA
LEASEQKFEFPVSWGLDLQSEHERYLAEVLCKKPVIVTNYPQEIKGFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREER
LEILDRRMDECNLNKEHYQWYRDLRRYGTVPHAGFGLGFERLISYVTGVSNVRDVIPFPRTPGHADY

Sequences:

>Translated_467_residues
MTEVFTIKQCLDGEISIDETVTVRGWVKTRRDSKAGLSFISLHDGSCFSPIQIVATDQLSNYQKEVTKLTAGCSMIATGK
LVASQGKGQFFEIQAESIEVVGWVENPDTYPIQAKRHTLEFLREVAHLRPRTNTISAVTRVRHSLAQAIHRFYHEQGFFW
VHTPIITASDCEGAGEMFRVSTLDLLNIPKNDKGQIDFSKDFFGRETFLTVSGQLNVEAYCMAMSKVYTFGPTFRAENSN
TSRHLAEFWMIEPEIAFANLEDICKLSQNMLRYLCKTVLEERSDDMDFFNQFVAPGCIERMEHIADSEFEIMTYTDAIKA
LEASEQKFEFPVSWGLDLQSEHERYLAEVLCKKPVIVTNYPQEIKGFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREER
LEILDRRMDECNLNKEHYQWYRDLRRYGTVPHAGFGLGFERLISYVTGVSNVRDVIPFPRTPGHADY
>Mature_466_residues
TEVFTIKQCLDGEISIDETVTVRGWVKTRRDSKAGLSFISLHDGSCFSPIQIVATDQLSNYQKEVTKLTAGCSMIATGKL
VASQGKGQFFEIQAESIEVVGWVENPDTYPIQAKRHTLEFLREVAHLRPRTNTISAVTRVRHSLAQAIHRFYHEQGFFWV
HTPIITASDCEGAGEMFRVSTLDLLNIPKNDKGQIDFSKDFFGRETFLTVSGQLNVEAYCMAMSKVYTFGPTFRAENSNT
SRHLAEFWMIEPEIAFANLEDICKLSQNMLRYLCKTVLEERSDDMDFFNQFVAPGCIERMEHIADSEFEIMTYTDAIKAL
EASEQKFEFPVSWGLDLQSEHERYLAEVLCKKPVIVTNYPQEIKGFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERL
EILDRRMDECNLNKEHYQWYRDLRRYGTVPHAGFGLGFERLISYVTGVSNVRDVIPFPRTPGHADY

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=462, Percent_Identity=42.6406926406926, Blast_Score=391, Evalue=1e-109,
Organism=Homo sapiens, GI4758762, Length=454, Percent_Identity=27.3127753303965, Blast_Score=172, Evalue=6e-43,
Organism=Homo sapiens, GI45439306, Length=349, Percent_Identity=28.6532951289398, Blast_Score=109, Evalue=7e-24,
Organism=Escherichia coli, GI1787161, Length=464, Percent_Identity=68.9655172413793, Blast_Score=700, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=470, Percent_Identity=24.0425531914894, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789256, Length=467, Percent_Identity=23.5546038543897, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17556372, Length=435, Percent_Identity=32.4137931034483, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI71984122, Length=453, Percent_Identity=29.5805739514349, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI17551876, Length=347, Percent_Identity=27.3775216138329, Blast_Score=105, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6319872, Length=476, Percent_Identity=34.6638655462185, Blast_Score=282, Evalue=7e-77,
Organism=Saccharomyces cerevisiae, GI6321807, Length=464, Percent_Identity=29.7413793103448, Blast_Score=185, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6323011, Length=344, Percent_Identity=26.7441860465116, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI19922416, Length=457, Percent_Identity=36.980306345733, Blast_Score=285, Evalue=6e-77,
Organism=Drosophila melanogaster, GI19921528, Length=467, Percent_Identity=28.6937901498929, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI17136276, Length=341, Percent_Identity=26.9794721407625, Blast_Score=105, Evalue=6e-23,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 53257; Mature: 53126

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVFTIKQCLDGEISIDETVTVRGWVKTRRDSKAGLSFISLHDGSCFSPIQIVATDQLS
CCCEEEHHHHCCCCCCCCCEEEEEHHHHHCCCCHHCCEEEEECCCCCCCCEEEEEEHHHH
NYQKEVTKLTAGCSMIATGKLVASQGKGQFFEIQAESIEVVGWVENPDTYPIQAKRHTLE
HHHHHHHHHHHCCCEEECCCEEECCCCCCEEEEEECCEEEEEEECCCCCCCCCHHHHHHH
FLREVAHLRPRTNTISAVTRVRHSLAQAIHRFYHEQGFFWVHTPIITASDCEGAGEMFRV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEE
STLDLLNIPKNDKGQIDFSKDFFGRETFLTVSGQLNVEAYCMAMSKVYTFGPTFRAENSN
EEEHEEECCCCCCCCEEECHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCC
TSRHLAEFWMIEPEIAFANLEDICKLSQNMLRYLCKTVLEERSDDMDFFNQFVAPGCIER
CHHHHHHHHEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
MEHIADSEFEIMTYTDAIKALEASEQKFEFPVSWGLDLQSEHERYLAEVLCKKPVIVTNY
HHHHCCCCEEEEEHHHHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECC
PQEIKGFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEILDRRMDECNLNKEHYQW
CHHHCEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
YRDLRRYGTVPHAGFGLGFERLISYVTGVSNVRDVIPFPRTPGHADY
HHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TEVFTIKQCLDGEISIDETVTVRGWVKTRRDSKAGLSFISLHDGSCFSPIQIVATDQLS
CCEEEHHHHCCCCCCCCCEEEEEHHHHHCCCCHHCCEEEEECCCCCCCCEEEEEEHHHH
NYQKEVTKLTAGCSMIATGKLVASQGKGQFFEIQAESIEVVGWVENPDTYPIQAKRHTLE
HHHHHHHHHHHCCCEEECCCEEECCCCCCEEEEEECCEEEEEEECCCCCCCCCHHHHHHH
FLREVAHLRPRTNTISAVTRVRHSLAQAIHRFYHEQGFFWVHTPIITASDCEGAGEMFRV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCEEEECCCCCCCCEEEE
STLDLLNIPKNDKGQIDFSKDFFGRETFLTVSGQLNVEAYCMAMSKVYTFGPTFRAENSN
EEEHEEECCCCCCCCEEECHHHCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEECCCCC
TSRHLAEFWMIEPEIAFANLEDICKLSQNMLRYLCKTVLEERSDDMDFFNQFVAPGCIER
CHHHHHHHHEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHH
MEHIADSEFEIMTYTDAIKALEASEQKFEFPVSWGLDLQSEHERYLAEVLCKKPVIVTNY
HHHHCCCCEEEEEHHHHHHHHHCCCHHEECCCCCCCCCCHHHHHHHHHHHHCCCEEEECC
PQEIKGFYMRLNDDGKTVAAMDVLAPGIGEIIGGSQREERLEILDRRMDECNLNKEHYQW
CHHHCEEEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHH
YRDLRRYGTVPHAGFGLGFERLISYVTGVSNVRDVIPFPRTPGHADY
HHHHHHHCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA