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The map label for this gene is ribA [H]

Identifier: 54295086

GI number: 54295086

Start: 2476861

End: 2478129

Strand: Direct

Name: ribA [H]

Synonym: lpl2166

Alternate gene names: 54295086

Gene position: 2476861-2478129 (Clockwise)

Preceding gene: 54295085

Following gene: 54295087

Centisome position: 74.03

GC content: 44.92

Gene sequence:

>1269_bases
ATGTCACCAGATGATTCAAAGAAAAAATCAAAAGGACACATTGTCTTGTCTTCACACCCGGCAAGCCATACACAAGCTCC
ATTAAAAATCAAATGGGGTGAAAAAAACCCTAAAGAGAGGGGGCCTGTTATTGCTTCTCTCACCAATATCAAAAATCGAA
ATGCCGTTGGAACTCACTCAGGGTCTTACTCTGTTTACAGGGCCTTGGCAGTAGCAGCTGGTCTGCTGGATCCCGAACAC
GTTCCTGATCTGACCGACACCCTGCCTCCTGTTGACATAGGGCCTCATAAGCAATGGGGAGAAGCAGGCAAAATTGTCTC
CCTCGATCCCTGGGGGCATCTAGTGGCTTCTGTTTTCTCAGAGGAAATAAAAGCCGGCTATGACATCAGACCAACCATTG
CCGTCACAAGGGCACATATTAATATCCCGGAATTGCATATTGCCATGCAAAAAGGCAGATTAAAACCTGATGGAAAAATT
TTAAGTGAAACAGGGGATGTCGTGGTGACTAAGGCCGCGATTGAACCAGTATGGTACTTGCCTGGAATTGCGGAGCGCTT
CCAGGTTTCAGAAGCATTGCTCAGACGCACTCTTTTTGAACAAACAGCTGGAATGTTCCCTGAACTGGTGACCCGTAGCG
ACTTGGATGTCTTTTTGCCACCCATTGGGGGATTAACTGCTTATTTCTTTGGTGATGTGACTACCATCCATAATCCGGAA
ATCGAATTAACTTGCCGTATTCATGATGAATGTAATGGCTCCGATGTCTTTGGTTCTGACATATGCACTTGCAGGCCATA
TTTGGTTCATGGAATCGAATTATCCATCGAATCCGCACAAAAAGGAGGCGCAGGCCTTATCGTTTATAATCGCAAAGAAG
GAAGAGCTCTTGGGGAGGTGACTAAATTTCTGGTTTATAACGCCAGAAAAAGACAGAAAGGTGGTGACACTGCAGCCAAG
TACTTTGAAAGAACGGAATGCGTAGCCGGTGTTCAGGATATGCGTTTCCAGGAATTAATGTCCGATATTCTTCATTGGCT
GGGGATCACTAAAATTCATCGCTTCGTTTCAATGTCCAATATGAAATACGATGCCTTGCTCAAATCCGGAATCAATGTTA
TTGAACGGGTAAAAATACCGGATGAGTTGATTCCTCCAGATGCCCGGGTAGAAATAGATGCCAAGCGTGCAGCAGGATAT
TACTCACCCGAAGGAATTATTGATATCAACGAATTGGCTAAACCGAAAGGACGTGCCCTTCATGAATAA

Upstream 100 bases:

>100_bases
TAGACAGTTTATAACAATAGTGTGCACCTGCTTATAAAGGGATAAAAGGTAAAACAACCGATTTATTTGAGCACCGTTGA
AACAAAAGGAATTAAGTATC

Downstream 100 bases:

>100_bases
TCAAGAGCAGCAAATACAAAATGTTTTGAATATGCTTCGTGATCCTCGCACCATAAGAACCCGGTCGCATCGTATTTTAA
ACTTGGCAAAACAGAATCGG

Product: hypothetical protein

Products: NA

Alternate protein names: GTP cyclohydrolase II [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHSGSYSVYRALAVAAGLLDPEH
VPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKGRLKPDGKI
LSETGDVVVTKAAIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGDVTTIHNPE
IELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEVTKFLVYNARKRQKGGDTAAK
YFERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEIDAKRAAGY
YSPEGIIDINELAKPKGRALHE

Sequences:

>Translated_422_residues
MSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHSGSYSVYRALAVAAGLLDPEH
VPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKGRLKPDGKI
LSETGDVVVTKAAIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGDVTTIHNPE
IELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEVTKFLVYNARKRQKGGDTAAK
YFERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEIDAKRAAGY
YSPEGIIDINELAKPKGRALHE
>Mature_421_residues
SPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHSGSYSVYRALAVAAGLLDPEHV
PDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFSEEIKAGYDIRPTIAVTRAHINIPELHIAMQKGRLKPDGKIL
SETGDVVVTKAAIEPVWYLPGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGDVTTIHNPEI
ELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEVTKFLVYNARKRQKGGDTAAKY
FERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSNMKYDALLKSGINVIERVKIPDELIPPDARVEIDAKRAAGYY
SPEGIIDINELAKPKGRALHE

Specific function: Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate [H]

COG id: COG0807

COG function: function code H; GTP cyclohydrolase II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase II family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000926 [H]

Pfam domain/function: PF00925 GTP_cyclohydro2 [H]

EC number: =3.5.4.25 [H]

Molecular weight: Translated: 46524; Mature: 46393

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHS
CCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHHHCCEEEEECCCCCCCCCCCCC
GSYSVYRALAVAAGLLDPEHVPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFS
CCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
EEIKAGYDIRPTIAVTRAHINIPELHIAMQKGRLKPDGKILSETGDVVVTKAAIEPVWYL
HHHHCCCCCCCEEEEEEEECCCCHHEEEHHCCCCCCCCCEECCCCCEEEEEHHHCCEEEC
PGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGDVTTIHNPE
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCHHHHHHCCEEEEECCC
IELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEV
EEEEEEECCCCCCCCCCCCCCCCCCHHHHEEEEEEEECCCCCCCEEEEEECCCCCHHHHH
TKFLVYNARKRQKGGDTAAKYFERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSN
HHHHHHCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MKYDALLKSGINVIERVKIPDELIPPDARVEIDAKRAAGYYSPEGIIDINELAKPKGRAL
CHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEHHHCCCCCCCCCCEEHHHHCCCCCCCC
HE
CC
>Mature Secondary Structure 
SPDDSKKKSKGHIVLSSHPASHTQAPLKIKWGEKNPKERGPVIASLTNIKNRNAVGTHS
CCCCCCCCCCCCEEEECCCCCCCCCCEEEECCCCCCHHHCCEEEEECCCCCCCCCCCCC
GSYSVYRALAVAAGLLDPEHVPDLTDTLPPVDIGPHKQWGEAGKIVSLDPWGHLVASVFS
CCHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHH
EEIKAGYDIRPTIAVTRAHINIPELHIAMQKGRLKPDGKILSETGDVVVTKAAIEPVWYL
HHHHCCCCCCCEEEEEEEECCCCHHEEEHHCCCCCCCCCEECCCCCEEEEEHHHCCEEEC
PGIAERFQVSEALLRRTLFEQTAGMFPELVTRSDLDVFLPPIGGLTAYFFGDVTTIHNPE
CCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCEEECCCCCHHHHHHCCEEEEECCC
IELTCRIHDECNGSDVFGSDICTCRPYLVHGIELSIESAQKGGAGLIVYNRKEGRALGEV
EEEEEEECCCCCCCCCCCCCCCCCCHHHHEEEEEEEECCCCCCCEEEEEECCCCCHHHHH
TKFLVYNARKRQKGGDTAAKYFERTECVAGVQDMRFQELMSDILHWLGITKIHRFVSMSN
HHHHHHCCHHHCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
MKYDALLKSGINVIERVKIPDELIPPDARVEIDAKRAAGYYSPEGIIDINELAKPKGRAL
CHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEEEHHHCCCCCCCCCCEEHHHHCCCCCCCC
HE
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA