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The map label for this gene is fabG [H]

Identifier: 54295077

GI number: 54295077

Start: 2465307

End: 2466059

Strand: Direct

Name: fabG [H]

Synonym: lpl2157

Alternate gene names: 54295077

Gene position: 2465307-2466059 (Clockwise)

Preceding gene: 54295076

Following gene: 54295078

Centisome position: 73.69

GC content: 40.64

Gene sequence:

>753_bases
ATGAATATCCTGATTACTGGCGGCTCCTCTGATATTGCCCAAGCCATAGCGAAACGACGCAGTGAATCAGGCGATAAGAT
CATCATTACCTGCTCTAACGACGACAGTCTTAATGAAACACTTGCAATATACCGCCAACAAAACATTGACGTGACGGGTT
TCATTTATAACTTTTCAGATCCTCAATCTTGTGAAAACGATTTGGAACTGATTTTAAGAGAACCACTTGATGGCATCATA
TTAAATGCGTTCACTCGGGTCACCCAACTGCGTAAATTACATGCATTGCCATATCACGCTGTTCGTACTTACCTGGATAA
CAATCTCAATGGCAACATTTGGCTTATTCATCGTTTATTACCTGCCTTGCTAAAAAATAAATTCGGGCGACTAGTCCTCA
TTTCAAGTCTTTCAGCAACAGCGGGCACCAGTCGATACCCTGTTTATTGTACGGCAAAAGCTGCTCTGGAAGGATTATTT
TTAAATTTGGCTGTTGATTATAGTGCTAACAATATCTTGTCTAACATAGTACGCGTAGGATTAATTAAAACCTCCAGAAC
AGAGCAATTCTGGAAAAATCCAGCCTATCAAGAAAAAGTAATACAAATTATTCCACAGGGCACTATGGGTGAACCAAGTC
AAGTTGCGGAAGCCATTGATCCACTTTTGTCAAAAACCTCGTTTATGACGGGATCAGTTGTAACAGTCAGTGGTGGTCTG
CCTTTAATGCGTTCAGAAGGATTGTTGTCATGA

Upstream 100 bases:

>100_bases
AACGTGAATTTGAAATTAAAATCCCTGTCATTCCACTGGAGAAAGAGCATTACGAATCGATCAATACTATTGAACAATAC
CTCATTGAGCTGGGGGCAAA

Downstream 100 bases:

>100_bases
ATTTTTTCCGTTGTGAAAAACCCATTTATATAAAAGGCCCTTTTGTTGCGCTTCCCGAGAGAGTCATGAGCAACCAAGAT
GTTCTCAATTGGATGAACAG

Product: hypothetical protein

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDDSLNETLAIYRQQNIDVTGFIYNFSDPQSCENDLELILREPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLF
LNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPSQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS

Sequences:

>Translated_250_residues
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDDSLNETLAIYRQQNIDVTGFIYNFSDPQSCENDLELILREPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLF
LNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPSQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS
>Mature_250_residues
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDDSLNETLAIYRQQNIDVTGFIYNFSDPQSCENDLELILREPLDGII
LNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLLPALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLF
LNLAVDYSANNILSNIVRVGLIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPSQVAEAIDPLLSKTSFMTGSVVTVSGGL
PLMRSEGLLS

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=241, Percent_Identity=24.896265560166, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=23.6734693877551, Blast_Score=71, Evalue=9e-13,
Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=28.2786885245902, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17560676, Length=251, Percent_Identity=25.0996015936255, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=25.3061224489796, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17559104, Length=264, Percent_Identity=27.2727272727273, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355319, Length=242, Percent_Identity=24.7933884297521, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24643142, Length=238, Percent_Identity=25.6302521008403, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 27514; Mature: 27514

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDDSLNETLAIYRQQNIDVTGFIYNFSD
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCC
PQSCENDLELILREPLDGIILNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEHHHHH
PALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLFLNLAVDYSANNILSNIVRVG
HHHHHHCCCCEEEEECCCCCCCCCCCCEEEEHHHHHCEEEEEEEEECCHHHHHHHHHHHH
LIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPSQVAEAIDPLLSKTSFMTGSVVTVSGGL
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PLMRSEGLLS
CCCCCCCCCC
>Mature Secondary Structure
MNILITGGSSDIAQAIAKRRSESGDKIIITCSNDDSLNETLAIYRQQNIDVTGFIYNFSD
CEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEEEEEECCC
PQSCENDLELILREPLDGIILNAFTRVTQLRKLHALPYHAVRTYLDNNLNGNIWLIHRLL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEEHHHHH
PALLKNKFGRLVLISSLSATAGTSRYPVYCTAKAALEGLFLNLAVDYSANNILSNIVRVG
HHHHHHCCCCEEEEECCCCCCCCCCCCEEEEHHHHHCEEEEEEEEECCHHHHHHHHHHHH
LIKTSRTEQFWKNPAYQEKVIQIIPQGTMGEPSQVAEAIDPLLSKTSFMTGSVVTVSGGL
HHCCCCHHHHHCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCC
PLMRSEGLLS
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]