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The map label for this gene is yybE [H]

Identifier: 54294971

GI number: 54294971

Start: 2298372

End: 2299277

Strand: Direct

Name: yybE [H]

Synonym: lpl2050

Alternate gene names: 54294971

Gene position: 2298372-2299277 (Clockwise)

Preceding gene: 54294970

Following gene: 54294976

Centisome position: 68.7

GC content: 35.87

Gene sequence:

>906_bases
ATGCACATGTCAGATATCAAGTCTTTCCTTGCGGTTGTTGAATTCCATTCCATATCATTAGCGTCTAAGAAAATGCACAT
ATCCCAACCTACTATGACGAGAAGAATTCAAAAAATTGAACAGGAATTAGGAACTCCCTTGTTTTTTTCTTCCGGAATAA
GGACTGAGCTTACAGCGAAAGGAAAGGAGCTTTTACCCTACTTTCGTCAGATGCTTGATATTTATCAGCAAATGTACATT
AATGTAGGTAATAAAACGAAAAACCCATTAAAGCTTATTAATGTAGGAACGTCGGTCTATGTTGCTAACTCCATTATTCA
AGATTTCATGCACAGCGCAGAAATTTCTTCCTCCAACTATTTTTTTAATATTAAATTACTAGCAGAACCTCATATAATAG
ATAGCTTAAACAGTGGAGAATATGACTTAATTATAGCCCCACCAGTGTATGATTGTTCCTCATCCGTTATATCTATCCCC
TTATGGAAAGAAAAAATTTTAGCTGTGGTTGGAGCAAGCCATCCTCTGGCGAGAAATAAAAAAGCCATTTCAATCACCGA
GCTAATGTCTCATGATGTTGCCCTGATGGAAAAAGGTTTTACCCTTCGCAAAAAATTAGATTTCTTATCGGAGAAGCTTC
ATACTCCTCTAAAAGCCATTTTCGAGTCAAACAGCATTTATAATAACATCGCATTGATTGAAAAAGGGGTTGGGTGGTGT
CTAATTCATGAACGCCTGCTCAATCCTAACTTAATTCCTGTTGAGTTATCCGATTGCAACATGGAAATTGAATTTCATTG
CTCATTTTTAAAAAGAAGAGAAGATGAACGTTTAATTTGGCAATTTCTAGAACAGATTCGCAAATGGATTTTGGCAGATT
ATTTAAAACAATATGCATGCCCATGA

Upstream 100 bases:

>100_bases
GAATCGAACATGGTTTATTGATATTTTTATGATATGGCACAATACTTAGGTTAGACAATGAATGCGAGCAGACTCTCAAA
GATATGAGGTAAACATAAAT

Downstream 100 bases:

>100_bases
ACATTATGGATGCATTCTAACCGTTAAATTTTATTTTAGGAAACGTCCCATGACCCGGTTTTATAGTAGGCCATGGGATA
AAATCATATCAGACAAAATT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MHMSDIKSFLAVVEFHSISLASKKMHISQPTMTRRIQKIEQELGTPLFFSSGIRTELTAKGKELLPYFRQMLDIYQQMYI
NVGNKTKNPLKLINVGTSVYVANSIIQDFMHSAEISSSNYFFNIKLLAEPHIIDSLNSGEYDLIIAPPVYDCSSSVISIP
LWKEKILAVVGASHPLARNKKAISITELMSHDVALMEKGFTLRKKLDFLSEKLHTPLKAIFESNSIYNNIALIEKGVGWC
LIHERLLNPNLIPVELSDCNMEIEFHCSFLKRREDERLIWQFLEQIRKWILADYLKQYACP

Sequences:

>Translated_301_residues
MHMSDIKSFLAVVEFHSISLASKKMHISQPTMTRRIQKIEQELGTPLFFSSGIRTELTAKGKELLPYFRQMLDIYQQMYI
NVGNKTKNPLKLINVGTSVYVANSIIQDFMHSAEISSSNYFFNIKLLAEPHIIDSLNSGEYDLIIAPPVYDCSSSVISIP
LWKEKILAVVGASHPLARNKKAISITELMSHDVALMEKGFTLRKKLDFLSEKLHTPLKAIFESNSIYNNIALIEKGVGWC
LIHERLLNPNLIPVELSDCNMEIEFHCSFLKRREDERLIWQFLEQIRKWILADYLKQYACP
>Mature_301_residues
MHMSDIKSFLAVVEFHSISLASKKMHISQPTMTRRIQKIEQELGTPLFFSSGIRTELTAKGKELLPYFRQMLDIYQQMYI
NVGNKTKNPLKLINVGTSVYVANSIIQDFMHSAEISSSNYFFNIKLLAEPHIIDSLNSGEYDLIIAPPVYDCSSSVISIP
LWKEKILAVVGASHPLARNKKAISITELMSHDVALMEKGFTLRKKLDFLSEKLHTPLKAIFESNSIYNNIALIEKGVGWC
LIHERLLNPNLIPVELSDCNMEIEFHCSFLKRREDERLIWQFLEQIRKWILADYLKQYACP

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=235, Percent_Identity=28.5106382978723, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790399, Length=210, Percent_Identity=26.1904761904762, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787530, Length=268, Percent_Identity=23.5074626865672, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=24.0816326530612, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34581; Mature: 34581

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHMSDIKSFLAVVEFHSISLASKKMHISQPTMTRRIQKIEQELGTPLFFSSGIRTELTAK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEHHCC
GKELLPYFRQMLDIYQQMYINVGNKTKNPLKLINVGTSVYVANSIIQDFMHSAEISSSNY
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCE
FFNIKLLAEPHIIDSLNSGEYDLIIAPPVYDCSSSVISIPLWKEKILAVVGASHPLARNK
EEEEEEEECCHHHHCCCCCCEEEEECCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCC
KAISITELMSHDVALMEKGFTLRKKLDFLSEKLHTPLKAIFESNSIYNNIALIEKGVGWC
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCCCE
LIHERLLNPNLIPVELSDCNMEIEFHCSFLKRREDERLIWQFLEQIRKWILADYLKQYAC
EHHHHHCCCCEEEEEECCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
P
C
>Mature Secondary Structure
MHMSDIKSFLAVVEFHSISLASKKMHISQPTMTRRIQKIEQELGTPLFFSSGIRTELTAK
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCEEHHCC
GKELLPYFRQMLDIYQQMYINVGNKTKNPLKLINVGTSVYVANSIIQDFMHSAEISSSNY
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCCE
FFNIKLLAEPHIIDSLNSGEYDLIIAPPVYDCSSSVISIPLWKEKILAVVGASHPLARNK
EEEEEEEECCHHHHCCCCCCEEEEECCCCCCCCCCEEECCCHHHHHHHHHCCCCCCCCCC
KAISITELMSHDVALMEKGFTLRKKLDFLSEKLHTPLKAIFESNSIYNNIALIEKGVGWC
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHCCCCCE
LIHERLLNPNLIPVELSDCNMEIEFHCSFLKRREDERLIWQFLEQIRKWILADYLKQYAC
EHHHHHCCCCEEEEEECCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]